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Editable PPT - Science Prof Online
Editable PPT - Science Prof Online

... to the latent, recurring infections typical of this group. ...
STROKE PPG VIRAL/GENE TRANSFER CORE: Request for a new
STROKE PPG VIRAL/GENE TRANSFER CORE: Request for a new

... What type of cells do you want gene of interest expressed in? Level and duration of expression desired? How important is cell-type specificity? Is toxicity of the gene of interest a concern? Special requests (inducible expression, siRNA, dominant negative) What services do you want the viral core to ...
Unit 9 Tax Microbes
Unit 9 Tax Microbes

... *destroys/inhibit T cell production ...
Place Invaders: Invasive Diseases
Place Invaders: Invasive Diseases

... plants are infected with viruses little can be done. There is not effective treatment. The best control is prevention. Scientists are working on creating vaccines but they are in the early stages of research. ...
Virus
Virus

... In bacterial viruses, the cycle of viral infection, replication, and cell destruction is called the __________ cycle. A substance that can inhibit the growth of or kill some microorganisms is called a __________. A virus that infects a bacteria is a __________. An __________ is a substance that stim ...
Transcript
Transcript

... new ones, and viral pathogenesis—how viruses cause disease and escape from the immune system. 2) One of the things you want to remember when we talk about viruses is the molecular biology dogma, and that dogma is DNA -> RNA -> Protein. DNA in eukaryotic cells is in the nucleus; it gets transcribed t ...
In general, viruses have very small genomes which means they can
In general, viruses have very small genomes which means they can

... In general, viruses have very small genomes which means they can encode a very limited number of their own proteins. For this reason, most viruses must use the proteins provided by their host in order to reproduce (make more viruses). In a way, viruses are parasitic, they bring very little with them ...
Virus/Bacteria Quiz
Virus/Bacteria Quiz

... b. Viruses can reproduce only using a host cell. c. Viruses can reproduce on their own at any time. d. Viruses contain DNA, so they are alive. 3. Prokaryotic cells differ from eukaryotic cells in that a. prokaryotic cells are living and eukaryotic cells are nonliving. b. prokaryotic cells lack a tru ...
18.1 Studying Viruses and Prokaryotes
18.1 Studying Viruses and Prokaryotes

... • Viruses can reproduce only by using the structures of a living cell called the host cell • Viruses are pathogens = can cause an infectious disease ...
Ebola strain variation in outbreaks
Ebola strain variation in outbreaks

... The Ebola virus (EBOV) is one the most lethal pathogens with a structure similar to a filovirus. Its length varies from 800-1000 nm long and roughly 288 amino acids long. The amount of attenuations is what makes this particular virus so interesting, and deadly. Virons are generally tubular and can a ...
Titan Tutoring for Biology
Titan Tutoring for Biology

...  A genetically inherited disease that distorts the red blood cells and prevents hemoglobin from functioning (properly).  Having the sickle cell trait _____________________________.  Malaria is caused by the parasitic protist ______________________. It is transmitted through a mosquito vector wher ...
Medical Virology - Med Study Group
Medical Virology - Med Study Group

... • Prions are rather ill-defined infectious agents believed to consist of a single type of protein molecule with no nucleic acid component. Confusion arises from the fact that the prion protein & the gene which encodes it are also found in normal 'uninfected' cells. These agents are associated with d ...
HOW HIV INFECTS CELLS
HOW HIV INFECTS CELLS

... In general, viruses have very small genomes, which means they can encode a very limited number of their own proteins. For this reason, most viruses must use the proteins provided by their host in order to reproduce (make more viruses). In a way, viruses are parasitic, they bring very little with the ...
how hiv infects cells - hrsbstaff.ednet.ns.ca
how hiv infects cells - hrsbstaff.ednet.ns.ca

... DNA - reverse transcriptase, an enzyme that is unique to viruses. Color the reverse transcriptase yellow. Because the HIV virus uses the reverse transcriptase and RNA method, it is known as a retrovirus. The Flu is another example of a retrovirus. Because it is single stranded genetic material, it d ...
Zika Virus in a Patient With Cancer: How Much Do
Zika Virus in a Patient With Cancer: How Much Do

... some serologic tests. Dengue virus immunoassays were negative, but indirect immunofluorescence assays for Zika virus demonstrated both immunoglobulin M (IgM) and IgG high titers. The patient is now recovered and had no neurologic symptoms. This case illustrates some difficulties in diagnosing Zika v ...
transcript - American Chemical Society
transcript - American Chemical Society

... containing a powerful anti-inflammatory drug that at its normal dose would be too toxic to use with patients suffering from acute liver failure, for example. However, when Dr. Murthy and his collaborators loaded this drug into their polyketal microparticles and injected this formulation into mice su ...
10.4 Don`t Bug Me - Texarkana Independent School District
10.4 Don`t Bug Me - Texarkana Independent School District

... 1. Why do viruses not have a scientific name? They are not technically alive, so they cannot be classified by living classification systems. 2. What are the parts of a virus? Genetic material carried in a shell called a viral coat or capsid which is made up of proteins. Some have an additional layer ...
Odds for Controls
Odds for Controls

... insect vector. • When an insect vector is involved, the disease is also known as an arboviral disease. • However, not all arboviral diseases are zoonosis: where the transmission cycle takes place exclusively between insect vector and human e.g. dengue and urban yellow fever. • Examples of viral zoon ...
Module 1 - Ivy Tech
Module 1 - Ivy Tech

... 2. difference between how they reproduce 3. how they interact with cells differently 4. how virus cause infectious diseases 5. international travel how does that open up more of a risk to us ...
Viral Infectious Diseases – Hinh Ly
Viral Infectious Diseases – Hinh Ly

... Goal: develop an understanding of immune responses in emergence of viral variants in the swine popula on and develop new approaches for protec on against influenza Drs. Maxim Cheeran, Srinand Sreevatsan, Montsera Torremorel and Tom Molitor Viral behavior in the host ...
Two relevant eukaryotic viruses
Two relevant eukaryotic viruses

... 1. Make contact with host cell—usually specific 2. Bind to a receptor on the cell surface 3. Enter the cell via endocytosis or fusion of membranes 4. Uncoat the virus to reveal the nucleic acids RNA virus –cytoplasm DNA and retroviruses must enter nucleus first 5. Translate mRNA or + stranded RNA th ...
Viruses, Bacteria, Protists and Fungi
Viruses, Bacteria, Protists and Fungi

... virus. The 2014 Ebola epidemic is the largest in history, affecting multiple countries in West Africa. The risk of an Ebola outbreak affecting multiple people in the U.S. is very low. ...
Chapter 12: The Viruses and Virus
Chapter 12: The Viruses and Virus

... • This prevents the release of new virions into the body • Interferon Puts Cells in an Antiviral State • Interferon (IFN) is a group of naturally-produced proteins that alert cells to a viral infection • Some IFNs have anti-cancer properties • Cells in an antiviral state can inhibit viral replicatio ...
Bacteria & Viruses Chapters 24 & 25
Bacteria & Viruses Chapters 24 & 25

... DNA viruses enter a host cell, begin directing the cell to make more viruses RNA viruses (retroviruses) enter host cell, and using reverse transcriptase, use their RNA to make a template for DNA and the new DNA directs cell to make more viruses Page 489 chart on viruses affecting ...
TAKS Review - Bowie Academic Chemistry Resources
TAKS Review - Bowie Academic Chemistry Resources

... Enzymes allow viruses to insert their genetic material into the host cell’s DNA. The virus benefits from this action by — A acquiring the traits of the host cell B causing the host cell to produce viruses C introducing random deadly mutations into the host cell D turning the host cell into a virus ...
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Oncolytic virus

An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by lysis, they release new infectious virus particles to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune responses.The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research efforts did not begin until the 1960s. A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been clinically tested as oncolytic agents. Most current oncolytic viruses are engineered for tumour selectivity, although there are naturally occurring examples such as reovirus and the SVV-001 Seneca Valley virus, resulting in clinical trials.As of 2011, only limited human trials had been performed.Nevertheless, the drug talimogene laherparepvec (OncoVex, T-VEC) recently (Jan 2012) reported the first positive interim Phase III clinical trial results for an oncolytic virus, making it likely that it will also be the first one approved for use (for the treatment of advanced melanoma). However, skeptics have questioned the clinical relevance of this interim data citing that the awaited overall survival data will be the final judgement and that it is likely that patient benefit will be maximised in combination with other therapies, which this trial did not test. 2015 update: In a combined decision, members of the FDA’s Oncologic Drugs Advisory Committee (ODAC) and Cellular, Tissue and Gene Therapies Advisory Committee (CTGTAC) voted 22-1 to recommend approval of the oncolytic immunotherapy talimogene laherparepvec (T-VEC) as a treatment for patients with advanced melanoma. A final approval decision from the FDA is scheduled by October 27, 2015. Approved in Latvia oncolytic virus RIGVIR was registered in Georgia in February 2015. Melanoma Research published new data on RIGVIR efficacy, showing that early stage melanoma patients treated with oncolytic virus RIGVIR had 4.39–6.57-fold lower mortality than those, who according to melanoma treatment guidelines did not receive virotherapy and were only observed.
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