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UNIT 5: Introduction to Virology
UNIT 5: Introduction to Virology

...  Maturation: after the assemble the virion mature and exit from cell after the lysis of cell to infect new cells. ...
Old Exam#3
Old Exam#3

... B. Input and output particles were similar, therefore there was no infection C. One would expect new viral types (for example H2N8) if the particles had been collected much later, because antigenic drift requires time scales longer than 30 days D. Only H1N2 and H4N2 came out, therefore no mixing of ...
Viruses, viroids, prions
Viruses, viroids, prions

... • Lysogeny = incorporation into host DNA – Latent period in animal cells • Trigger stimulates cell to enter lytic cycle • 3 important results – 1. Lysogenic cells are immune to infection by same virus – 2. Host cell may exhibit new properties • C. diphtheriae requires presence of temperate virus to ...
Genetics of Viruses and Bacteria-ap
Genetics of Viruses and Bacteria-ap

... A hypothesis of how infectious protein particles, or prions, cause ...
The immunology of virus infection in asthma
The immunology of virus infection in asthma

... Viral URI are a major cause of wheezing in infants and adult patients with asthma Molecular biological techniques such as PCR or RT-PCR for the detection of viral infection in the asthma exacerbations Indirect evidence from the population studies seasonal variation in wheezing episodes in young chi ...
Antiviral Agents – Dr.Roshna
Antiviral Agents – Dr.Roshna

... acutely infected with HAV should avoid alcohol and other hepatotoxic medications until they have fully recovered. ...
Plant Viruses - rci.rutgers.edu
Plant Viruses - rci.rutgers.edu

... Infectious – must be transmissible horizontally Intracellular – require living cells RNA or DNA genome, not both* Most all have protein coat* May of may not have lipid envelope May have broad or narrow host range Replication involves eclipse (breaking apart of virus particles) and reassembly • Use h ...
respiratory viral infections 2015 updated2016-02-07
respiratory viral infections 2015 updated2016-02-07

...  Lab diagnosis: routine testing by Direct detection of Influenza A or B virus from sputum, nasopharyngeal swab, aspirate (NPA) or respiratory secretion by direct immunoflourecent assay (IFA).  Other detection methods: tissue culture, PCR.  Treatment: 1: Amantadine is effective against influenza A ...
Paracytology and virology 2nd stage Germs: Viruses, Bacteria, and
Paracytology and virology 2nd stage Germs: Viruses, Bacteria, and

... The term 'germ' actually refers to any microorganism, especially those microorganisms that cause disease. Included in this category are certain viruses, bacteria, and fungi. What is the difference between these three types of microbes? Which ones cause which diseases, and should they be treated diff ...
L1- Mechanism of aut..
L1- Mechanism of aut..

... – About 90% of autoimmune diseases occur in women – cause not known – In animal models estrogen can induce B cells to enhance formation of antiDNA antibodies – SLE either appears or exacerbates during pregnancy ...
Chapter 36: Picornaviruses (Enterovirus & Rhinovirus Groups)
Chapter 36: Picornaviruses (Enterovirus & Rhinovirus Groups)

... secretory IgA antibodies in the intestine, which then becomes resistant to reinfection.  Both killed-virus and live-virus vaccines induce antibodies and protect the central nervous system from subsequent invasion by wild virus. ...
TOPIC 6.3
TOPIC 6.3

... are used to detect the presence or absence of a particular protein • For example, people recently infected with HIV will initially produce antibodies against HIV. These antibodies can be detected by ELISA to determine if a patient is HIV positive or negative ...
Virus Structure Lecture PowerPoint
Virus Structure Lecture PowerPoint

... • The SPO Virtual Classrooms offer many educational resources, including practice test questions, review questions, lecture PowerPoints, video tutorials, sample assignments and course syllabi. New materials are continually being developed, so check back frequently, or follow us on Facebook (Science ...
pathogen
pathogen

... S Infective agents can be transmitted from one host to another by: S Direct contact S Droplets in air breathed or sneezed out by an infected person S Sexual contact S Contaminated food or water S A carrying vector, eg. rats carrying fleas S An injecting vector, eg. mosquitoes carrying malarial paras ...
The immune system
The immune system

... fungistatic, etc.), which means they stop further growth, but don't kill existing cells. ...
Text S3: Probability of extinction Our results show that long
Text S3: Probability of extinction Our results show that long

... Figure S2). The virological efficacy is not quite perfect however, because of a small fraction of patients who shed resistant virus (proportion of subject shedding resistant virus and proportion of virus shed that is resistant <2.5%, see Figure S3). Taken together we conclude that any symptomatic in ...
Viruses and Bacteria
Viruses and Bacteria

... They cannot reproduce without a host cell. The virus will inject a material into the host cell to take over all it's functions. The cell will eventually reproduce, but reproduces the virus not its original reproductions. ...
Viruses
Viruses

... • Viruses are obligate intracellular pathogens that can infect all types of living organisms. • Viruses that infect bacteria are called: Bacteriophages. • Many human diseases are caused by viruses. • Some viruses “oncogenic viruses” can even cause cancers e.g. leukemia, lymphoma.. • Virus particles ...
Bacteria and Viruses
Bacteria and Viruses

... produce DNA copies of their RNA genes. • Retroviruses have their genetic information copied backwards. RNA  DNA • One Ex of a retrovirus is HIV. Others cause cancer in animals and humans. • The theory is that viruses were not the first living things. They are dependent on living things to survive. ...
AP Biology 12 Viruses
AP Biology 12 Viruses

...  Bacteriophages were grown in a medium containing radioactive sulfur (35S) and radioactive phosphorous (32P), which are incorporated into proteins and DNA, respectively. If these phages were used to infect a bacterial culture, which isotope would be detected within the infected bacteria? A. 35S B. ...
case study
case study

... £70 billion so a measure with the potential to limit the spread of viral infection is worthy of including in an infection control strategy. The evidence described here suggests the application of BioCote® antiviral technology has the potential to complement strategies aimed at inhibiting the spread ...
Slide 1
Slide 1

... genomes than do cells • May be DNA or RNA; never both • Primary way scientists categorize and classify viruses • Can be dsDNA, ssDNA, dsRNA, ssRNA • May be linear and composed of several segments or single and circular • Much smaller than genomes of cells ...
1- الوضع الوبائى لحمى الوادي المتصدع في مصر والمملكة العربية
1- الوضع الوبائى لحمى الوادي المتصدع في مصر والمملكة العربية

... Objective: The present study aimed to investigate the clinical and clinicopathological findings of .arthritic camel calf associated with mycoplasma infection in district areas of Saudi Arabia Metho ‫ حقائق وبائية‬:‫ مرض فيروس زيكا‬-5 Zika virus disease is a disease caused by Zika virus leads to symp ...
Viral virulence genes
Viral virulence genes

... • Viral  inhibiNon  of  host  protein  and  RNA  synthesis,  leads   to  loss  of  membrane  integrity,  leakage  of  enzymes  from   lysosomes,  cytoplasmic  degradaNon   • SyncyNum  formaNon  by  enveloped  viruses   (parainfluenza,  HIV)   • ...
Name: Date: Period: 1.22 Virus Reading Are viruses Alive? Anyone
Name: Date: Period: 1.22 Virus Reading Are viruses Alive? Anyone

... its protein coat; therefore it does not grow. 17. Why doesn’t a virus grow? Plants and animals react to the environment. All living things have ways of sensing the world around them and can respond to changes in their environment. Do viruses react? Viruses cannot move themselves and cannot react by ...
< 1 ... 16 17 18 19 20 21 22 23 24 ... 32 >

Oncolytic virus

An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by lysis, they release new infectious virus particles to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune responses.The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research efforts did not begin until the 1960s. A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been clinically tested as oncolytic agents. Most current oncolytic viruses are engineered for tumour selectivity, although there are naturally occurring examples such as reovirus and the SVV-001 Seneca Valley virus, resulting in clinical trials.As of 2011, only limited human trials had been performed.Nevertheless, the drug talimogene laherparepvec (OncoVex, T-VEC) recently (Jan 2012) reported the first positive interim Phase III clinical trial results for an oncolytic virus, making it likely that it will also be the first one approved for use (for the treatment of advanced melanoma). However, skeptics have questioned the clinical relevance of this interim data citing that the awaited overall survival data will be the final judgement and that it is likely that patient benefit will be maximised in combination with other therapies, which this trial did not test. 2015 update: In a combined decision, members of the FDA’s Oncologic Drugs Advisory Committee (ODAC) and Cellular, Tissue and Gene Therapies Advisory Committee (CTGTAC) voted 22-1 to recommend approval of the oncolytic immunotherapy talimogene laherparepvec (T-VEC) as a treatment for patients with advanced melanoma. A final approval decision from the FDA is scheduled by October 27, 2015. Approved in Latvia oncolytic virus RIGVIR was registered in Georgia in February 2015. Melanoma Research published new data on RIGVIR efficacy, showing that early stage melanoma patients treated with oncolytic virus RIGVIR had 4.39–6.57-fold lower mortality than those, who according to melanoma treatment guidelines did not receive virotherapy and were only observed.
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