Motor proteins of the kinesin superfamily
... positioning and chemistry in the active site, imply that kinesins and myosins have evolved from an ancestral motor protein. An evolutionary connection to G-proteins is more tenuous; however, the shared structural, functional and chemical features of motors and these GTPases hint that an ancestral nu ...
... positioning and chemistry in the active site, imply that kinesins and myosins have evolved from an ancestral motor protein. An evolutionary connection to G-proteins is more tenuous; however, the shared structural, functional and chemical features of motors and these GTPases hint that an ancestral nu ...
View/Open - Minerva Access
... Aurein was able to translocate from either lipid environment, indicating a weaker binding to lipid membranes, and a different molecular mechanism for lysis of lipid bilayers. Competitive lipid environments could be used to assess other critical parameters that modulate the activity of membrane pepti ...
... Aurein was able to translocate from either lipid environment, indicating a weaker binding to lipid membranes, and a different molecular mechanism for lysis of lipid bilayers. Competitive lipid environments could be used to assess other critical parameters that modulate the activity of membrane pepti ...
schoeneich_oxidants
... SCN- levels, have larger numbers of lipid-laden macrophages than non-smokers [20]. Unlike HOCl, which has been shown to react with a wide range of biological targets (though primarily proteins) [21-23], HOSCN reacts with great specificity with thiols (both glutathione (GSH) and protein cysteine (Cys ...
... SCN- levels, have larger numbers of lipid-laden macrophages than non-smokers [20]. Unlike HOCl, which has been shown to react with a wide range of biological targets (though primarily proteins) [21-23], HOSCN reacts with great specificity with thiols (both glutathione (GSH) and protein cysteine (Cys ...
Retinoblastoma Protein Contains a C-terminal - Bio
... Examination of the primary sequence of the pRB C terminus showed that this region contained several candidate cyclincdk2 binding motifs between residues 829 and 928. Site-directed mutagenesis identified one such motif, beginning at residue 870, that was necessary for efficient phosphorylation of pRB ...
... Examination of the primary sequence of the pRB C terminus showed that this region contained several candidate cyclincdk2 binding motifs between residues 829 and 928. Site-directed mutagenesis identified one such motif, beginning at residue 870, that was necessary for efficient phosphorylation of pRB ...
A Receptor-Like Kinase Mediates Ammonium
... Ling Bai,1 Xiaonan Ma,1 Guozeng Zhang,1 Shufei Song, Yun Zhou, Lijie Gao, Yuchen Miao, and Chun-Peng Song2 Institute of Plant Stress Biology, State Key Laboratory of Cotton Biology, Department of Biology, Henan University, Kaifeng 475001, China ...
... Ling Bai,1 Xiaonan Ma,1 Guozeng Zhang,1 Shufei Song, Yun Zhou, Lijie Gao, Yuchen Miao, and Chun-Peng Song2 Institute of Plant Stress Biology, State Key Laboratory of Cotton Biology, Department of Biology, Henan University, Kaifeng 475001, China ...
- Gastroenterology
... trypsin in the initiating events of pancreatitis can be assumed because trypsin mutations are the most common autosomal-dominant changes associated with pancreatitis.1–3 In the absence of enterokinase in the pancreas, other mechanisms must be operative through which a premature and intrapancreatic a ...
... trypsin in the initiating events of pancreatitis can be assumed because trypsin mutations are the most common autosomal-dominant changes associated with pancreatitis.1–3 In the absence of enterokinase in the pancreas, other mechanisms must be operative through which a premature and intrapancreatic a ...
Induction of floor plate differentiation by contact
... 1992), suggesting that the floor plate also contributes to the normal patterning of ventral cell types. In vivo studies have emphasized the role of the notochord and the floor plate in the control of early neural pattern, but do not permit analysis of the nature or mechanism of action of inducing si ...
... 1992), suggesting that the floor plate also contributes to the normal patterning of ventral cell types. In vivo studies have emphasized the role of the notochord and the floor plate in the control of early neural pattern, but do not permit analysis of the nature or mechanism of action of inducing si ...
The role of c-di-GMP signaling in an Aeromonas veronii biovar
... Published by Blackwell Publishing Ltd. All rights reserved ...
... Published by Blackwell Publishing Ltd. All rights reserved ...
The Plant Membrane-Associated REMORIN1.3 Accumulates in
... The online version of this article contains Web-only data. www.plantphysiol.org/cgi/doi/10.1104/pp.114.235804 ...
... The online version of this article contains Web-only data. www.plantphysiol.org/cgi/doi/10.1104/pp.114.235804 ...
1 Sister chromatids are often incompletely cohesed
... 0.001) from the random ratio of 2:1 (random separation involving one homologue should be twice as frequent as separation involving both homologues). The larger-than-expected proportion of nuclei with four signals might suggest a tendency for simultaneous separation of sister chromatids of both homol ...
... 0.001) from the random ratio of 2:1 (random separation involving one homologue should be twice as frequent as separation involving both homologues). The larger-than-expected proportion of nuclei with four signals might suggest a tendency for simultaneous separation of sister chromatids of both homol ...
ABSTRACT Title of Document:
... progenitors enter the thymus in three waves during embryonic life (e6.5, e12 and e18). T cell progenitors from each wave undergo a period of extensive proliferation within the thymic cortex that lasts up to three weeks (e7 - day7 posthatch, e12 - d12, and e18- d18) (Cooper et al., 1991). These waves ...
... progenitors enter the thymus in three waves during embryonic life (e6.5, e12 and e18). T cell progenitors from each wave undergo a period of extensive proliferation within the thymic cortex that lasts up to three weeks (e7 - day7 posthatch, e12 - d12, and e18- d18) (Cooper et al., 1991). These waves ...
REVIEWS - Unisciel
... overlapped by thick filaments is termed the light, isotropic I-band. A very dense, narrow Z-line bisects the I-band. A central, less dense region of the A-band is known as the H-band, and this, in turn, is bisected by a dark M-line. The assembly of thick and thin filaments into bundles in register i ...
... overlapped by thick filaments is termed the light, isotropic I-band. A very dense, narrow Z-line bisects the I-band. A central, less dense region of the A-band is known as the H-band, and this, in turn, is bisected by a dark M-line. The assembly of thick and thin filaments into bundles in register i ...
The head organizer in Hydra
... The head organizer in Hydra plays no role in the head organizer as animals in which all the cells of the interstitial cell lineage have been removed behave normally when hand-fed in that their shape and size as well as epithelial cell division and the resulting tissue movements as well as bud forma ...
... The head organizer in Hydra plays no role in the head organizer as animals in which all the cells of the interstitial cell lineage have been removed behave normally when hand-fed in that their shape and size as well as epithelial cell division and the resulting tissue movements as well as bud forma ...
Plasma Gelsolin
... D. Gelsolin Interacts with Plasma ATP in a Ca2+-Dependent Manner Despite the low physiological concentration of ATP in plasma (~550 nM) compared to its intracellular concentration of 3-10 mM [55], plasma ATP exerts important effects through binding to its plasma membrane purinergic receptors. Most c ...
... D. Gelsolin Interacts with Plasma ATP in a Ca2+-Dependent Manner Despite the low physiological concentration of ATP in plasma (~550 nM) compared to its intracellular concentration of 3-10 mM [55], plasma ATP exerts important effects through binding to its plasma membrane purinergic receptors. Most c ...
Mitochondrial fusion dynamics is robust in the heart and depends on
... microscopy has shown that acute exercise results in increased structural interactions among mitochondria (29). In addition, elevated Mfn1 and Mfn2 mRNA levels (30), as well as increased mitochondrial continuity (20), have been observed after exercise. Finally, slow-twitch/oxidative fibers that are p ...
... microscopy has shown that acute exercise results in increased structural interactions among mitochondria (29). In addition, elevated Mfn1 and Mfn2 mRNA levels (30), as well as increased mitochondrial continuity (20), have been observed after exercise. Finally, slow-twitch/oxidative fibers that are p ...
Cenp-A Presence in Drosophila - Institute of Molecular Life Sciences
... Author Summary Genetic information in eukaryotic cells is parceled into chromosomes. These information strings are precisely transmitted to daughter cells during mitotic and meiotic cell divisions, but only if the centromere, a specialized chromosomal region, is functional. The centromere region wit ...
... Author Summary Genetic information in eukaryotic cells is parceled into chromosomes. These information strings are precisely transmitted to daughter cells during mitotic and meiotic cell divisions, but only if the centromere, a specialized chromosomal region, is functional. The centromere region wit ...
Exogenous Free Ubiquitin Enhances Lily Pollen
... applied on both reducing (Fig. 6A, left) and nonreducing (Fig. 6A, right) SDS-PAGE gels. This was done because Sulfo-SBED contains a disulfide bridge. Biotin was clearly detected in the nonreducing gel at 10-kD size, which corresponds to the unlabeled SCA, as shown in Figure 6A (right). This implies ...
... applied on both reducing (Fig. 6A, left) and nonreducing (Fig. 6A, right) SDS-PAGE gels. This was done because Sulfo-SBED contains a disulfide bridge. Biotin was clearly detected in the nonreducing gel at 10-kD size, which corresponds to the unlabeled SCA, as shown in Figure 6A (right). This implies ...
Active Transport of the Survival Motor Neuron Protein and
... SMN is localized to both the nucleus and cytoplasm, and considerable attention has focused on concentration of SMN in nuclear dot-like structures termed gems (Liu and Dreyfuss, 1996) and coiled (Cajal) bodies (Carvalho et al., 1999; Young et al., 2000). There have been extensive studies, in various ...
... SMN is localized to both the nucleus and cytoplasm, and considerable attention has focused on concentration of SMN in nuclear dot-like structures termed gems (Liu and Dreyfuss, 1996) and coiled (Cajal) bodies (Carvalho et al., 1999; Young et al., 2000). There have been extensive studies, in various ...
Altered morphology produced by ftsZ expression in
... Homologous overexpression of FtsZ has been also studied in Neisseria gonorrhoeae (Salimnia et al., 2000), Halobacterium salinarum (Margolin et al., 1996) and Mycobacterium tuberculosis (Dziadek et al., 2002), among others. In N. gonorrhoeae, the expression of FtsZ resulted in abnormal cell division ...
... Homologous overexpression of FtsZ has been also studied in Neisseria gonorrhoeae (Salimnia et al., 2000), Halobacterium salinarum (Margolin et al., 1996) and Mycobacterium tuberculosis (Dziadek et al., 2002), among others. In N. gonorrhoeae, the expression of FtsZ resulted in abnormal cell division ...
By I\ 0. BOWER, M.A., Camb., Assistant to the Professor of Botany in
... retain their cell nature, and play an active part in the further development (cf. below). At the periphery of the section lies a layer of cork derived from a phellogen layer, as already described. Since the same is the case in sections from older roots, the fact will not be again mentioned. It may b ...
... retain their cell nature, and play an active part in the further development (cf. below). At the periphery of the section lies a layer of cork derived from a phellogen layer, as already described. Since the same is the case in sections from older roots, the fact will not be again mentioned. It may b ...
C-terminal processing of yeast Spt7 occurs in the absence of
... TAFs and other SAGA-specific components [19]. The additional Spt proteins, Spt3 and Spt8 are involved in direct interactions with TBP [3,22-25]. Tra1, a 437 kDa, phosphatidylinositol-3-kinase related protein [26,27] is found at the periphery of the complex and interacts with DNAbinding transcription ...
... TAFs and other SAGA-specific components [19]. The additional Spt proteins, Spt3 and Spt8 are involved in direct interactions with TBP [3,22-25]. Tra1, a 437 kDa, phosphatidylinositol-3-kinase related protein [26,27] is found at the periphery of the complex and interacts with DNAbinding transcription ...
Polycystin-1 maturation requires polycystin-2 in a dose
... block the severing (10, 11). Rapidly progressive PKD develops when cleavage is blocked (12), underscoring the importance of this region for PC1 function. Several subcellular localizations have been suggested for the polycystins, including cilia, plasma membrane (PM), exosomelike vesicles (ELVs), and ...
... block the severing (10, 11). Rapidly progressive PKD develops when cleavage is blocked (12), underscoring the importance of this region for PC1 function. Several subcellular localizations have been suggested for the polycystins, including cilia, plasma membrane (PM), exosomelike vesicles (ELVs), and ...
as Hotspot Ca 2+ Signaling Units
... membrane (OMM and IMM respectively). Despite the surprisingly low affinity of the mitochondrial uptake systems (Kd around 10–20 mM) and the submicromolar global [Ca2+]c (which rarely exceed 2–3 mM) evoked by IP3-mediated Ca2+ release, mitochondrial Ca2+ concentration ([Ca2+]m) can undergo rapid chan ...
... membrane (OMM and IMM respectively). Despite the surprisingly low affinity of the mitochondrial uptake systems (Kd around 10–20 mM) and the submicromolar global [Ca2+]c (which rarely exceed 2–3 mM) evoked by IP3-mediated Ca2+ release, mitochondrial Ca2+ concentration ([Ca2+]m) can undergo rapid chan ...
Characterization of Vincristine Transport by the Mr 190,000
... Inhibition of [3H]VCR Transport by MRP-specific MAbs. Sev eral MRP-specific MAbs have been shown to inhibit MRP-mediated transport of LTC4, 17ß-estradiol 17-(ß-D-glucuronide), and aflatoxin B,-GSH (17, 26, 28). In the present study, we tested whether or not they would also inhibit GSH-stimulated V ...
... Inhibition of [3H]VCR Transport by MRP-specific MAbs. Sev eral MRP-specific MAbs have been shown to inhibit MRP-mediated transport of LTC4, 17ß-estradiol 17-(ß-D-glucuronide), and aflatoxin B,-GSH (17, 26, 28). In the present study, we tested whether or not they would also inhibit GSH-stimulated V ...
Co-translational Targeting and Translocation of the Amino Terminus
... of both cytosolic and ER-lumenal ATPase chaperones (14, 16, 17). The lumenal chaperone BiP (also known as Kar2 and Grp78) plays a critical role in yeast translocation. Both temperature-sensitive mutations in BiP and decreased expression of BiP cause translocation defects in vivo (18, 19). Proteolipo ...
... of both cytosolic and ER-lumenal ATPase chaperones (14, 16, 17). The lumenal chaperone BiP (also known as Kar2 and Grp78) plays a critical role in yeast translocation. Both temperature-sensitive mutations in BiP and decreased expression of BiP cause translocation defects in vivo (18, 19). Proteolipo ...
Cytokinesis
Cytokinesis (cyto- + kinesis) is the process during cell division in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the early stages of mitosis, and sometimes meiosis, splitting a mitotic cell in two, to ensure that chromosome number is maintained from one generation to the next. After cytokinesis two (daughter) cells will be formed that are exact copies of the (parent) original cell. After cytokinesis, each daughter cell is in the interphase portion of the cell cycle. In animal cells, one notable exception to the normal process of cytokinesis is oogenesis (the creation of an ovum in the ovarian follicle of the ovary), where the ovum takes almost all the cytoplasm and organelles, leaving very little for the resulting polar bodies, which then die. Another form of mitosis without cytokinesis occurs in the liver, yielding multinucleate cells. In plant cells, a dividing structure known as the cell plate forms within the centre of the cytoplasm and a new cell wall forms between the two daughter cells.Cytokinesis is distinguished from the prokaryotic process of binary fission.