hTERT Inhibition Triggers Epstein–Barr Virus Lytic Cycle and
... chemotherapeutic drugs are known to trigger EBV replication, including 5-fluorouracil, methotrexate, doxorubicin, and several histone deacetylase inhibitors (9–12). EBVcarrying tumor cells may also be killed by prodrugs, such as ganciclovir or radiolabeled nucleoside analogs, which are activated by ...
... chemotherapeutic drugs are known to trigger EBV replication, including 5-fluorouracil, methotrexate, doxorubicin, and several histone deacetylase inhibitors (9–12). EBVcarrying tumor cells may also be killed by prodrugs, such as ganciclovir or radiolabeled nucleoside analogs, which are activated by ...
Regulated adhesion as a driving force of gastrulation movements
... often used to measure relative ‘adhesiveness’ between cells, because cells with higher affinity end up in the centre of reaggregates, surrounded by cells with lower affinity (Steinberg, 2007). Several variants of the assay exist, for instance, incubating cells in ‘hanging drops’ or re-transplanting ...
... often used to measure relative ‘adhesiveness’ between cells, because cells with higher affinity end up in the centre of reaggregates, surrounded by cells with lower affinity (Steinberg, 2007). Several variants of the assay exist, for instance, incubating cells in ‘hanging drops’ or re-transplanting ...
Bacteria - Edmonds
... in Gram neg. bacteria. Help the bacteria stick to surfaces. Also forms conjugation bridge Chromosome – a single loop of DNA that is folded on itself, controls the cell’s function Nucleoid – the region of the cytoplasm where the DNA is found Plasmid – an accessory loop of DNA – small contains only a ...
... in Gram neg. bacteria. Help the bacteria stick to surfaces. Also forms conjugation bridge Chromosome – a single loop of DNA that is folded on itself, controls the cell’s function Nucleoid – the region of the cytoplasm where the DNA is found Plasmid – an accessory loop of DNA – small contains only a ...
Second Harmonic Imaging of Plant Polysaccharides
... Plants depend on polysaccharides for structural functions that in animal cells are carried out by proteins. The plant cell wall consists of a matrix of more or less amorphous polysaccharides reinforced by microfibrils of highly crystalline cellulose, a β 1:4 linked glucan. In some tissues (typically ...
... Plants depend on polysaccharides for structural functions that in animal cells are carried out by proteins. The plant cell wall consists of a matrix of more or less amorphous polysaccharides reinforced by microfibrils of highly crystalline cellulose, a β 1:4 linked glucan. In some tissues (typically ...
Chapter 3.05
... 6-O-sulfation of the second Gal residue, inhibit the transfer of a GlcA residue by GlcAT-I.24 Thus, the sulfation of specific positions of the two Gal residues may regulate the expression level of GAGs by affecting the activity of GlcAT-I, although further experiments including the cloning of sulfot ...
... 6-O-sulfation of the second Gal residue, inhibit the transfer of a GlcA residue by GlcAT-I.24 Thus, the sulfation of specific positions of the two Gal residues may regulate the expression level of GAGs by affecting the activity of GlcAT-I, although further experiments including the cloning of sulfot ...
Cell surface monoamine oxidases: enzymes in search of a function
... reduced cofactor recycles back to its oxidized TPQ form. During this process hydrogen peroxide and ammonia are released. It is generally agreed that SSAOs only accept primary amines as substrates, although there may be exceptions to this rule (Yu and Davis, 1990). Nevertheless, there appears to be w ...
... reduced cofactor recycles back to its oxidized TPQ form. During this process hydrogen peroxide and ammonia are released. It is generally agreed that SSAOs only accept primary amines as substrates, although there may be exceptions to this rule (Yu and Davis, 1990). Nevertheless, there appears to be w ...
9700/04 - StudyGuide.PK
... (a) Describe the importance of ATP in cells, giving two examples of processes in which it is used. ...
... (a) Describe the importance of ATP in cells, giving two examples of processes in which it is used. ...
THP-1 - Cancer Research
... membrane-related processes, studying these changes in mem brane properties during the differentiation and functional matura tion of macrophages is important. Tissue TGase, an intracellular enzyme that catalyzes the covalent cross-linking of proteins via f-(7-glutaminyl)lysine isopeptide bonds (5), a ...
... membrane-related processes, studying these changes in mem brane properties during the differentiation and functional matura tion of macrophages is important. Tissue TGase, an intracellular enzyme that catalyzes the covalent cross-linking of proteins via f-(7-glutaminyl)lysine isopeptide bonds (5), a ...
Nuclear Factor of Activated T Cells - JEM
... phospho-CREB–binding site and CBP4 includes the E1Abinding site (Fig. 3 A). Equivalent amounts of each GST fusion protein were used in the binding assay as seen by Ponceau red staining (data not shown). Binding between CBP and NFAT was specific because no immunoreactive band was seen with GST alone ...
... phospho-CREB–binding site and CBP4 includes the E1Abinding site (Fig. 3 A). Equivalent amounts of each GST fusion protein were used in the binding assay as seen by Ponceau red staining (data not shown). Binding between CBP and NFAT was specific because no immunoreactive band was seen with GST alone ...
Distinct gene expression signatures in human embryonic stem cells
... populations are needed. Individual cells in a seemingly homogenous cultures or tissues are in many aspects unique in their expression of transcripts and proteins [36]. This implies that cell population data cannot be used to accurately describe individual cells. Immunocytochemistry provides an oppor ...
... populations are needed. Individual cells in a seemingly homogenous cultures or tissues are in many aspects unique in their expression of transcripts and proteins [36]. This implies that cell population data cannot be used to accurately describe individual cells. Immunocytochemistry provides an oppor ...
1 A generalized quantitative antibody homeostasis model
... shown to be required for B-cell development 17. A simple – and by Occam’s razor most likely - possibility to provide a feedback to newly forming IgM producing precursor cells is to display antigenic target molecules on the cells themselves. We suggest that pre-BI and pre-BII cells present antigens b ...
... shown to be required for B-cell development 17. A simple – and by Occam’s razor most likely - possibility to provide a feedback to newly forming IgM producing precursor cells is to display antigenic target molecules on the cells themselves. We suggest that pre-BI and pre-BII cells present antigens b ...
Nonredox 5-Lipoxygenase Inhibitors Require Glutathione
... in Dulbecco’s PBS. When intact cells were assayed, the cells (2– 103106) were finally resuspended in 1 ml PBS (with 1 mM Ca21, 1 g/liter glucose) and preincubated for 5–10 min with the test compounds at room temperature. Then, the reaction was started by addition of arachidonic acid and ionophore A2 ...
... in Dulbecco’s PBS. When intact cells were assayed, the cells (2– 103106) were finally resuspended in 1 ml PBS (with 1 mM Ca21, 1 g/liter glucose) and preincubated for 5–10 min with the test compounds at room temperature. Then, the reaction was started by addition of arachidonic acid and ionophore A2 ...
receptive field properties in the cat`s lateral geniculate nucleus in the
... found over a 4-hr period following injection. stored information regarding response variability in the Other evidence suggests that nonspecific damage did form of standard deviations, computed separately for the not occur. First, in most experiments we recorded from number of spikes fired during the ...
... found over a 4-hr period following injection. stored information regarding response variability in the Other evidence suggests that nonspecific damage did form of standard deviations, computed separately for the not occur. First, in most experiments we recorded from number of spikes fired during the ...
The measurement of exocytosis in plant cells
... plasma membrane growth and for its differentiation during the life of the cell is incorporated from the secretory vesicle membrane during exocytosis. For each of these processes (polysaccharide, protein and phospholipid delivery) there may be alternative routes, but the available evidence suggests t ...
... plasma membrane growth and for its differentiation during the life of the cell is incorporated from the secretory vesicle membrane during exocytosis. For each of these processes (polysaccharide, protein and phospholipid delivery) there may be alternative routes, but the available evidence suggests t ...
Penetration and Establishment of Phakopsora pachyrhizi in
... went through papillar material and traversed the host epidermal cell to reach the lower epidermal cell wall (Fig. 2C). The penetration pore in the upper epidermal cell wall had the edge of the host cuticle pushed part way into the pore (Fig. 2C). However, there appeared to be little, if any, indicat ...
... went through papillar material and traversed the host epidermal cell to reach the lower epidermal cell wall (Fig. 2C). The penetration pore in the upper epidermal cell wall had the edge of the host cuticle pushed part way into the pore (Fig. 2C). However, there appeared to be little, if any, indicat ...
Bellairs pm6.5 - The International Journal of Developmental Biology
... These were also found to exhibit ruffled membranes and contact inhibition of locomotion. Such findings would be of limited interest if they applied only to cells in culture but Abercrombie’s aim was to explain how cells moved in vivo and how they ceased to migrate once they reached their destination ...
... These were also found to exhibit ruffled membranes and contact inhibition of locomotion. Such findings would be of limited interest if they applied only to cells in culture but Abercrombie’s aim was to explain how cells moved in vivo and how they ceased to migrate once they reached their destination ...
ANTIBACTERIAL ACTIVITY OF HUMAN NATURAL KILLER CELLS
... contained >95% of the NK activity based on cytotoxicity of K562 targets, and comprised N5-10% of the starting MDC . Fraction 1 and 2 contained 79-80% LGL by morphology in Wright-Giemsa stained cytopreparations, and the percentage of monocytes was <0 .1% by staining with nonspecific esterase and dire ...
... contained >95% of the NK activity based on cytotoxicity of K562 targets, and comprised N5-10% of the starting MDC . Fraction 1 and 2 contained 79-80% LGL by morphology in Wright-Giemsa stained cytopreparations, and the percentage of monocytes was <0 .1% by staining with nonspecific esterase and dire ...
The Bacterial Nucleoid
... replication ; OM, outer membrane; PG, peptidoglycan; CM, cytoplasmicmembrane. ...
... replication ; OM, outer membrane; PG, peptidoglycan; CM, cytoplasmicmembrane. ...
Moss Systems Biology en Route
... in plant evolution (Paponov et al., 2005). This places the Physcomitrella PIN genes close to the root of the plant-specific gene tree. Initial results of targeted knockout approaches for either PpPIN1 or PpPIN2 demonstrated only minor phenotypic aberrations in leaflet morphology compared to the wild ...
... in plant evolution (Paponov et al., 2005). This places the Physcomitrella PIN genes close to the root of the plant-specific gene tree. Initial results of targeted knockout approaches for either PpPIN1 or PpPIN2 demonstrated only minor phenotypic aberrations in leaflet morphology compared to the wild ...
Relating the mechanics of the primary plant cell
... expansion per se is driven by turgor pressure, the spatiotemporal control of the process relies on the mechanics of the cell wall (Geitmann and Ortega, 2009). The cell wall not only confines the growth behavior of the individual cell but also regulates the development of the entire tissue, since nei ...
... expansion per se is driven by turgor pressure, the spatiotemporal control of the process relies on the mechanics of the cell wall (Geitmann and Ortega, 2009). The cell wall not only confines the growth behavior of the individual cell but also regulates the development of the entire tissue, since nei ...
Regulation of Vascular Development - Size
... differentiate in appropriate numbers and spatial relationships that give a functional whole. Developing vascular tissues must be able to carry out their functions in expanding organs; this is particularly challenging in grasses and other groups of plants where leaves and stems grow from the base, an ...
... differentiate in appropriate numbers and spatial relationships that give a functional whole. Developing vascular tissues must be able to carry out their functions in expanding organs; this is particularly challenging in grasses and other groups of plants where leaves and stems grow from the base, an ...
Activation of Src Kinases p53/56@ and p59hckby @ in Myeloid Cells`
... To establish a model system for the study of signaling events induced by p2l0@i@@@t, the murine, myeboid, IL-3-dependent cell line 32D was transfected with the plasmid pGD21O as described in “Materialsand Methods.―The resulting cell line 32Dp2l0 stably expressed the kinase; it could be grown wit ...
... To establish a model system for the study of signaling events induced by p2l0@i@@@t, the murine, myeboid, IL-3-dependent cell line 32D was transfected with the plasmid pGD21O as described in “Materialsand Methods.―The resulting cell line 32Dp2l0 stably expressed the kinase; it could be grown wit ...
Lab Part 1: Culturing and Isolating Bacteria
... d. convert ammonia in the soil into nitrogen gas. Cell organelles that Escherichia coli and other bacteria have in common with eukaryotes are a. chloroplasts. c. nuclei. b. mitochondria. d. ribosomes. Bacterial cells such as Escherichia coli transfer pieces of genetic material in a process called a. ...
... d. convert ammonia in the soil into nitrogen gas. Cell organelles that Escherichia coli and other bacteria have in common with eukaryotes are a. chloroplasts. c. nuclei. b. mitochondria. d. ribosomes. Bacterial cells such as Escherichia coli transfer pieces of genetic material in a process called a. ...
Mitosis
Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.