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(zolpidem CR) Fact Sheet - The Main Line Center for the Family
(zolpidem CR) Fact Sheet - The Main Line Center for the Family

... • Most common: drowsiness and dizziness. • Does not alter normal sleep stages. • Anecdotal: uncommonly, can cause black outs (loss of memory of activities) soon after ingested if the patient does not go right to sleep. • Classified as a Schedule IV drug, but abuse potential is likely somewhat less t ...
Mendelian Genetics Test Review Sheet
Mendelian Genetics Test Review Sheet

... The ABO blood groups, discovered by Dr. Karl Landsteiner, are based on the presence or absence of specific _______________ on the surface of red blood cells. ...
The Economics of Commercial Success in Pharmaceutical Patent
The Economics of Commercial Success in Pharmaceutical Patent

... clinical trials and publish their findings. Thus, over time new information may become available about a drug’s therapeutic properties. A study of anti-ulcer drugs found that sales respond to new scientific evidence in the form of published clinical trial results.13 Other studies have found that FDA ...
The Use of Therapeutic Interchange for Biologic Therapies
The Use of Therapeutic Interchange for Biologic Therapies

... drug that will reduce overall treatment costs (AMCP 2003). Therapeutic interchange programs are guided by evidence-based prescribing guidelines and by clinical trial data that suggest a class of drugs might be appropriate for interchange, having demonstrated similar patient outcomes while reducing p ...
Medication Interactions
Medication Interactions

... Drugs and their metabolites are excreted primarily through: a. sweat. b. saliva. ...
Name_________________ Pd___________________ Socratic
Name_________________ Pd___________________ Socratic

... Even among those who are already suffering memory loss, Alzheimer's is far from the only source. An estimated four million Americans have it, but millions more suffer from other disorders that can lead to dementia, including Parkinson's disease, multiple sclerosis, stroke, head trauma and schizophre ...
BIO II: Mendelian/Human Genetics Test Review Sheet A couple who
BIO II: Mendelian/Human Genetics Test Review Sheet A couple who

... The ABO blood groups, discovered by Dr. Karl Landsteiner, are based on the presence or absence of specific _______________ on the surface of red blood cells. ...
Notion about Psychological Disorders. Physiological Basis
Notion about Psychological Disorders. Physiological Basis

... mimicking, or influencing a particular neurotransmitter’s effects. The biological effects of a given drug vary somewhat from one person to another. • The person’s weight, gender, and age may influence the intensity of the drug’s effects. Whether the drug is taken on a full or empty stomach or in com ...
Drug Induced Liver Injury (DILI) - The University of North Carolina at
Drug Induced Liver Injury (DILI) - The University of North Carolina at

... reversibility of ALT elevations 1). ALT elevations that reverse on treatment have no relationship to those that can progress to liver failure. ...


... and that it is reasonable to project similar plasma levels, whether this total daily dose is given as 60 mg every 4 to 6 hours or as 60 mg Additionally, every 6 hours. there is insufficient evidence in these data to show that an increase in adverse reactions occurs from administration of the drug at ...
Introduction to Genetics
Introduction to Genetics

... Punnett Squares- used to predict and compare the genetic variations that will result from a cross. ...
Introduction to Genetics
Introduction to Genetics

... Punnett Squares- used to predict and compare the genetic variations that will result from a cross. ...
Itraconazole
Itraconazole

... Absorption is impaired when gastric acidity is reduced. In patients receiving acid neutralizing medicines (e.g. aluminium hydroxide), these should be administered at least 2 hours after the intake of Itraconazole. The drug should be administered after a full meal. Rarely, cases of hepatitis and jaun ...
Sympathomimetics
Sympathomimetics

... While they produce similar pharmacological actions, there are differences in effect on individuals depending on the relative stimulation of the various neurotransmitter systems (e.g. increased serotonin causes increased hallucinogenic effect). ...


...  No known interaction with Cytochrome P450 (CYP3A)  No known interaction with disease to avoid toxic reactions  Efficacy for all nasal symptoms including nasal obstruction  Improvement of eye symptoms  Improvement of asthma symptoms(short term studies)  Reduction of asthma exacerbations(long t ...
OPIOID ANALGESICS
OPIOID ANALGESICS

... an obstructed cystic duct, which of the following agents would be the drug of choice for the treatment of this patient’s pain? ...
Drugs to thin your blood
Drugs to thin your blood

... If your INR is above the target range, there is an increased risk of bleeding. You should monitor for the related signs and symptoms and seek immediate medical care should they occur. • Signs of bleeding: Please refer to the section on “What are the possible side effects” If you have history of dru ...
Gregor Mendel`s Discoveries- Mendel, a monk, discovered the basic
Gregor Mendel`s Discoveries- Mendel, a monk, discovered the basic

... and degeneration of motor and mental performance in infants soon after birth. - Usually children with Tay-Sachs disease do not live more than a few years - The disease is most common in Ashkenazic Jews than in any other population c. Sickle-Cell Disease - Sickle Cell disease affects 1/400 African Am ...
Genetics Unit
Genetics Unit

... Augustinian monk and botanist whose experiments in breeding garden peas led to his eventual recognition as founder of the science of genetics (1822-1884) ...
ONS Congress 2016
ONS Congress 2016

... • Courses are designed to provide interaction between learners with varying levels of expertise • Opportunity to interact with course facilitators • Facilitators review information posted by learners and may ask for additional detail and/or correct information that may be incorrect • Learners have t ...
Hx - Palliative Care
Hx - Palliative Care

... The most common side effects associated with methylphenidate include headache, nausea, vomiting, anorexia, dizziness, and insomnia. ...
ACTI-VIR ® 200 mg Tablets Dear patient, Please read
ACTI-VIR ® 200 mg Tablets Dear patient, Please read

... - Inform your doctor before using this medication in case of pregnancy or lactation. Limited data are available on the use of acyclovir during pregnancy. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Associations with other medicat ...
Abuse and Diversion of Controlled Substances
Abuse and Diversion of Controlled Substances

... morphine, oxycodone, meperidine, hydromorphone and codeine preparations), sedatives/hypnotics (e.g. benzodiazepines) and stimulants (e.g. amphetamines, methylphenidate). Anecdotal evidence from family practitioners in Canada indicates that the drugs most commonly requested by name in the office sett ...
Magellan Health Services – Southeast Care
Magellan Health Services – Southeast Care

... Administer a substance use screening tool, such as the Alcohol Use Disorders Identification Test (AUDIT)1 or the CAGE-AID.2 The first three questions of the AUDIT can be used alone to detect up to 80 percent of patients with mild to moderate alcohol use problems. The CAGE-AID is more appropriate to ...
Drugs for RA
Drugs for RA

... provides cardiovascular protection. Prolonged decrease in PGI2 produces these adverse cardiovascular effects DI: CYP2C9 inhibition, so you don’t metabolize fluconazole (A trizole) and fluvastatin ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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