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File - Siegel Science
File - Siegel Science

... Codominance=more than one allele is dominant, both are expressed equally Ex. blood types in humans There are actually 3 alleles for the blood type trait in humans (A, B, and O) ...
Penny Lab
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... 18. PTC Taster 19. Tongue Rolling 20. Hitchhiker’s Thumb ...
NSAID
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... least five receptor subtypes have been identified. In addition to the triptans, other drugs acting at serotonergic receptors include the popular antianxiety agents fluoxetine (Prozac) and buspirone (BuSpar). Pharmacotherapy of migraine termination generally begins with acetaminophen or NSAIDs. If OT ...
1) The Smallest Unit of Evolution
1) The Smallest Unit of Evolution

... 14) Calculating allele frequency in a population: • For diploid organisms, the total number of alleles at a locus is the total number of individuals x 2 • The total number of dominant alleles at a locus is 2 alleles for each homozygous dominant individual plus 1 allele for each heterozygous individ ...
Preparing a Business Case for a New Medicine
Preparing a Business Case for a New Medicine

... e. For medicines that have an unusually wide usage (and a significant cost pressure) may need to take a more corporate approach. Seek advice of MRG committee members for guidance e.g. fidaxomicin antibiotic for C.Difficile f. Where a medicine is low cost, a “must do” e.g. as per NICE and trust wide ...
anticonvulsant medications for
anticonvulsant medications for

... Common dose related adverse effects Initiation of anticonvulsants is associated with a number of very common dose related adverse effects including: ▪▪ Sedation, tiredness, dizziness, ataxia, tremor, ...
Topic D HL past paper questions 2011 (M10 – TZ2) Drugs can be
Topic D HL past paper questions 2011 (M10 – TZ2) Drugs can be

... 27. (M08) Some medicines prescribed by doctors are classified as depressants. These depress the central nervous system. One depressant not prescribed by doctors but widely used in some societies is ethanol. (a) Describe two long-term effects of consuming large quantities of ethanol on the human body ...
nicotinic receptors
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Chapter 9: Patterns of Inheritance
Chapter 9: Patterns of Inheritance

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Genetics pt 1 1314
Genetics pt 1 1314

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Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington

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Alcohol and Drug Policy - Central European University
Alcohol and Drug Policy - Central European University

... Central European University prohibits the irresponsible or unlawful possession, use, or distribution of alcohol and drugs by students, faculty, and staff on university premises or as part of any of its activities. In accordance with U.S. federal law, this policy applies to (1) any enrolled student r ...
ICD电风暴药物优化治疗新疆医科大学一附院心脏中心汤宝鹏ICD电
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... From May 2003, bumetanide (Burinex) was removed from the Schedule of Pharmaceutical Benefits; while the product continues to be available privately in Australia, companies often review the commercial viability of ongoing supply in such cases and future availability cannot be guaranteed. Consequently ...
Herbal Herbal Highs
Herbal Herbal Highs

... While BZP-based drugs are marketed as providing a natural euphoric rush and high, they are not without their dangers. BZP has been reported to produce myriad harmful side-effects and can cause unpredictable and serious toxicity. Just as with the illicit drug "ecstasy," immediate adverse effects may ...
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MENDEL AND THE GENE IDEA

... Hydrangea flowers vary in shade and intensity of color depending on acidity and aluminum content of the soil. ...
Alcohol and Drug Policy - Central European University
Alcohol and Drug Policy - Central European University

... Central European University prohibits the irresponsible or unlawful possession, use, or distribution of alcohol and drugs by students, faculty, and staff on university premises or as part of any of its activities. In accordance with U.S. federal law, this policy applies to (1) any enrolled student r ...
Ch 14 Lecture
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... 1. Phenotypic information is gathered from as many members of a family across generations. 2. The information can then be mapped onto a family tree. ...
Narcotic analgesics
Narcotic analgesics

... The enteric neurons contain both µ and delta receptors and if either of this receptor is activated , peristalsis of the GIT is inhibition. The characteristic constriction of pupil is also produced through µ and delta receptors . the physical dependence of morphine and the euphoric effect is also med ...
Pharmacologic Treatment of Acute Major Depression and Dysthymia
Pharmacologic Treatment of Acute Major Depression and Dysthymia

... decisions, or feelings of hopelessness. This guideline is based on an evidence report on pharmacotherapies for depression from the San Antonio Evidence-based Practice Center that was commissioned by the Agency for Healthcare Research and Quality (1). It answers the following questions: What is the e ...
PRESCRIBING GUIDELINES FOR BENZODIAZEPINES In ADULTS
PRESCRIBING GUIDELINES FOR BENZODIAZEPINES In ADULTS

... gradually after long-term use. Guidance on managing withdrawal can be found http://cks.nice.org.uk/benzodiazepine-and-zdrug-withdrawal#azTab. Information on prescribing, including switching to diazepam can also be found at www.bnf.org Patients should be referred to a specialist in the following circ ...
Genetic Inheritance Example
Genetic Inheritance Example

... Genetic Counseling and Prediction •  Take phenotype with known loci and observed phenotype and genotype data for individuals –  to infer genotype and phenotype for another person (planned child) ...
Slides_2
Slides_2

... Adverse Reactions generally mild and transient, include headache, malaise, anorexia, weakness, nausea, vomiting, and dizziness. Adverse effects also occur as a result of the release of proteins from dying microfilariae or adult worms. Reactions include fever, malaise, papular rash, headache, gastro ...
RETINITIS PIGMENTOSA - Foundation Fighting Blindness
RETINITIS PIGMENTOSA - Foundation Fighting Blindness

... individuals are participating in FFBfunded Phase I clinical trials of the treatment at The Children’s Hospital of Philadelphia (CHOP) and Moorfields Eye Hospital in London, as well as a study at the Universities of Pennsylvania and Florida. One nine-year-old boy has put away his white cane and can n ...
Technical Information Sheet
Technical Information Sheet

... Methods of Evaluation: Pantothenic acid concentration can be assessed in blood and urine. Structural and Functional Role: As a Coenzyme A precursor, pantothenic acid plays an essential role in the synthesis of fatty acids and modifications of cellular proteins with acetyl or fatty acyl groups includ ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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