• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
club drugs: an approach to review the hazard in indian scenario
club drugs: an approach to review the hazard in indian scenario

... Indian data on club drugs are very limited with little efforts being made to gather systematic data regarding the same. The first nationwide survey to obtain information on extent, pattern and magnitude of substance abuse in the country indicated new emerging trend of substance use in India with amp ...
alleles in gene pair are identical
alleles in gene pair are identical

... (Yellow) ...
Quantitative Genetic Perspectives on Loss of Diversity in
Quantitative Genetic Perspectives on Loss of Diversity in

... Implications for Elite x Exotic Crosses • Genetic variance within a single population is due mostly to genes of large effect • Linkage disequilibrium within the cross may reduce genetic variance • Any new alleles from the exotic parent are preferentially lost if: – Linked to negative alleles at phy ...
Targeting the Noncoding Genome with CRISPR
Targeting the Noncoding Genome with CRISPR

... enable us to discover the rules that govern these important parts of the genome.” Of the noncoding regulatory elements the team identified, what surprised Sanjana was that most of these would not have been found with traditional techniques used to identify open chromatin regions. Separately, Harvard ...
lfs internet
lfs internet

... recovering from breast cancer surgery and chemotherapy, seems very fragile as well as distraught that her son has a tumor-like growth. If Lee did, in fact, inherit a faulty gene from her that will predispose him to cancer, you are worried about how Grace will handle the news. She seems at great risk ...
Prescribing patterns of analgesic used in postoperative pain
Prescribing patterns of analgesic used in postoperative pain

... routinely or taken on an as-needed basis. If two drugs have been identified as having high potential to interact and cause harm, the pharmacist can contact the patient’s physician to obtain an order for another medication that will not cause the troublesome interaction. Pharmacist provide patient co ...
Title Page Option 1 (Title Case 38 Points) Presentation subtitle in
Title Page Option 1 (Title Case 38 Points) Presentation subtitle in

... • A person who is misusing prescription painkillers might take larger doses to achieve a euphoric effect and reduce withdrawal symptoms; larger doses can cause breathing to slow down so much that breathing stops, resulting in a fatal overdose ...
Why Opioids Are Addictive : Bio Energy Patch
Why Opioids Are Addictive : Bio Energy Patch

... and when, as well as how to stop taking them to lessen the chances of withdrawal symptoms. Eventually, the cells will work normally again, but that takes time. Someone who is addicted to opioids has other problems as well. For example, they keep taking the drug even though it may be having harmful e ...
Role of Alternative Medicine in Pandemic H1N1 Influenza
Role of Alternative Medicine in Pandemic H1N1 Influenza

... There are concerns that oseltamivir may cause dangerous psychological, neuropsychiatric side effects, including self harm harm in some users. These dangerous side effects occur more commonly in children than in adults. This stems from cases in Japan, where the drug is most heavily prescribed, consum ...
Genetics Terms You`ve Gotta Know
Genetics Terms You`ve Gotta Know

... gene are the same (AA or aa)  Heterozygous: When a person’s two alleles for a gene are different (Aa)  You get one allele from your mom and one from your dad.  If you get the same alleles from your mom and dad, you are homozygous for that trait.  If your mom gave you a different allele than your ...
Training
Training

... the mode of transmission of single gene traits • To construct a pedigree, the pattern of transmission of a phenotypic trait among individuals in a family is used to determine whether the mode of inheritance is dominant or recessive • Pedigree analysis is used to study single gene disorders, such as ...
Resource Presentation Pwpt - CIA-Biology-2011-2012
Resource Presentation Pwpt - CIA-Biology-2011-2012

...  D1.1 analyse, on the basis of research, some of the social and ethical implications of research in genetics and genomics (e.g., genetic screening, gene therapy, in vitro fertilization) [IP, PR, AI, C]  D1.2 evaluate, on the basis of research, the importance of some recent contributions to knowled ...
cancer - ichapps.com
cancer - ichapps.com

... Because of its reactivity, scarcely any drug is excreted. Adverse effects: The adverse effects caused by mechlorethamine include severe nausea, bone marrow depression, vomiting and Latent viral infections. Cyclophosphamide and ifosfamide: These drugs are very closely related mustard agents that shar ...
Epilepsy - Back to Medical School
Epilepsy - Back to Medical School

... reduce AEs  Rash common, sometimes severe and associated with StevenJohnson’s syndrome  Blood dyscrasias ...
7-Sedative Hypnotic
7-Sedative Hypnotic

... by thiopental as the last approach ...
Genetics and Heredity
Genetics and Heredity

... European descent but is much rarer in other groups. One out of 25 whites (4% ) is a carrier. The normal allele for this gene codes for a membrane protein that functions in chloride ion transport between certain cells and the extracellular fluid. These chloride channels are defective or absent. The r ...
Risk Reduction Strategies for High
Risk Reduction Strategies for High

... meningitis and dosed on actual body weight rather than adjusted body weight resulted in dose 20% higher than recommended. ...
genetics problems answers
genetics problems answers

... 7) All the offspring of a cross between a black-eyed mendelien and an orange-eyed mendelien have black eyes. What is the expected phenotypic ratio of a cross between two orange-eyed mendeliens? ...
Behavioral Health - PGXL Laboratories
Behavioral Health - PGXL Laboratories

... • New section on CYP2C19 sequencing and novel variants. This includes the novel *4B misclassification issue PGXL addresses in our recent abstract accepted to AMP 2013. • New section on novel candidate genes. • New section on who could be considered for CYP2C19 genotyping. Re-focus recommendations on ...
1. Explain what is meant by the “modern synthesis”.
1. Explain what is meant by the “modern synthesis”.

... deficiency which does not allow the body to process the amino acid phenylalanine. What percent of the population are carriers for this recessive disease? 1 in 10, 000 ; recessive = q2 ; q2 = .0001 ; q = .01 p = 1 – q ; p = 1 - .01 ; p = .99 p2 + 2pq + q2 = 1 ; 2pq = 2(.99)(.01) = .0198 therefore: 2% ...
PRAMIPEXOLE for Parkinson`s Disease
PRAMIPEXOLE for Parkinson`s Disease

... retina (seen in albino rats given high doses, but not reported in humans). If patients have visual problems or history of retinal disease baseline testing is recommended by an ophthalmologist. At review by consultant patients will be asked about any night vision problems and checked for visual field ...
FULL PRESCRIBING INFORMATION: CONTENTS* WARNING
FULL PRESCRIBING INFORMATION: CONTENTS* WARNING

... 8.4 Pediatric Use TRULANCE is contraindicated in pediatric patients less than 6 years of age. Avoid use of TRULANCE in patients 6 years to less than 18 years of age [see Contraindications (4), Warnings and Precautions (5.1)]. The safety and effectiveness of TRULANCE in patients less than 18 years of ...
Click here to download
Click here to download

... More emphasis on diet and exercise Less emphasis on meds for most people For fasting triglyceride levels of 150 to 199 mg/dL, focus on diet and exercise first. For fasting triglyceride levels of 200 to 499 mg/dL, diet and exercise should still be considered first. However, this is the point at ...
Document
Document

... • Drugs are used on a daily basis and are intended to prevent or decrease allergic reactions • Several weeks are usually required for the full therapeutic effect ...
here
here

... methods of drug delivery are limited to specific challenges that scientists are attempting to address. For example, many drugs’ potencies and therapeutic effects are limited or otherwise reduced because of the partial degradation that occurs before they reach their desired target in the body. The b ...
< 1 ... 842 843 844 845 846 847 848 849 850 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report