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Cxcl12/Cxcr4 signaling controls the migration and
Cxcl12/Cxcr4 signaling controls the migration and

... axon wiring. However, it is not known whether it regulates the development of A9-A10 tyrosine hydroxylase positive (TH+) midbrain dopaminergic (mDA) neurons. We report here that Cxcl12 is expressed in the meninges surrounding the ventral midbrain (VM), whereas CXCR4 is present in NURR1+ mDA precurso ...
Frontiers in Zoology - Deep Metazoan Phylogeny
Frontiers in Zoology - Deep Metazoan Phylogeny

... to illustrate the competing hypotheses on the position of Phylogram of the Bilateria based exclusively on molecular studies to illustrate the competing hypotheses on the position of Chaetognatha ("Chaetognatha 1–7") as suggested by molecular studies. The sources of the hypotheses 1 to 7 are indicate ...
Feedforward and feedback inhibition in neostriatal GABAergic spiny
Feedforward and feedback inhibition in neostriatal GABAergic spiny

... from rodent to primate (Kemp and Powell, 1971; Luk and Sadikot, 2001; Wilson, 2004 but see also Graveland and DiFiglia, 1985) are medium-sized spiny projection neurons that are also the only source of output from the nucleus. The remaining cell types comprise large aspiny cholinergic interneurons, a ...
Enhanced Modulation of Neuronal Activity during
Enhanced Modulation of Neuronal Activity during

... The present study used 3 saccade tasks (Fig. 1). In both the antisaccade task and the prosaccade task, a gray fixation point (10.7 cd/m2) initially appeared at the center of the screen. After 800 ms, color of the fixation point was changed either to green or red in order to instruct monkeys of the tri ...
Introduction
Introduction

... important role in neuronal injury and disease. Aberrant apoptosis can result in too little cell loss as seen in cancer progression, as well as too much cell loss such as following stroke, spinal cord injury and in many neurodegenerative diseases.1 A crucial event of apoptosis is the activation of ca ...
Brainstem (II)
Brainstem (II)

... Corticospinal axons continue into the pyramids of the medulla. At the spinomedullary junction, most corticospinal fiber decussate ...
A precocious adult visual center in the larva defines the unique optic
A precocious adult visual center in the larva defines the unique optic

... medulla and lobula are columnar neuropils sequentially linked by optic chiasmata, whereas the planar lobula plate receives uncrossed axons from the medulla and lobula and is characterized by wide-field tangential neurons [1]. Studies on dipterous insects have shown that these neurons, often having v ...
Multiple dynamic representations in the motor cortex
Multiple dynamic representations in the motor cortex

... L2/3 cells in vM1 receive strong input from vS1. To investigate which behaviours are represented by L2/3 cells during active somatosensation, we quantified how well specific behavioural variables could be decoded from neural activity37. We used random forests38, a generalized form of regression (Met ...
Pathways for emotions and memory
Pathways for emotions and memory

... Accepted 25 May 2002 ...
Dopamine is produced in the rat spinal cord and regulates
Dopamine is produced in the rat spinal cord and regulates

... Dopamine (DA) neurons in the mammalian central nervous system are thought to be restricted to the brain. DA-mediated regulation of urinary activity is considered to occur through an interaction between midbrain DA neurons and the pontine micturition center. Here we show that DA is produced in the ra ...
MECHANISMS OF CENTRAL TRANSMISSION OF RESPIRATORY
MECHANISMS OF CENTRAL TRANSMISSION OF RESPIRATORY

... Abstract. Several types of respiratory reflex actions can be discerned according to the reactions of typical respiratory neurons in the efferent part of the central rhythmogenic structure. Whereas respiration runs closely parallel with inspiratory neuron activity the behaviour of expiratory neurons ...
Soghomonian J.J., Sethares C., and Peters, A
Soghomonian J.J., Sethares C., and Peters, A

... Much of the cognitive decline shown by aging primates can be attributed to dysfunction of prefrontal cortex and, as shown previously, about 30% of asymmetric (excitatory) and symmetric (inhibitory) axodendritic synapses are lost from the neuropil of layer 2/3 in prefrontal area 46 with age (Peters e ...
Segundo trabajo
Segundo trabajo

... which activates several well-defined signaling cascades (Airaksinen and Saarma, 2002; Huang and Reichardt, 2003; Segal, 2003). The receptor tyrosine kinase Ret (Jing et al., 1996; Treanor et al., 1996; Trupp et al., 1996) is an important component in the signaling cascade activated by members of the ...
BMC Neuroscience Serial pathways from primate prefrontal cortex to autonomic areas
BMC Neuroscience Serial pathways from primate prefrontal cortex to autonomic areas

... (LA), anterior hypothalamic area, and posterior hypothalamic area. In the same experiment we found that prefrontal area 12 received projections from the basolateral (BL) and lateral (L) nuclei of the amygdala (Fig. 1F, red dots). We then used a different approach to obtain an overview of the origin ...
Function of Peripheral Olfactory Organs
Function of Peripheral Olfactory Organs

... Properties of Peripheral Olfactory Receptor Neurons 74 ...
A Circuit for Detection of Interaural Time Differences in the Brain
A Circuit for Detection of Interaural Time Differences in the Brain

... vessels as a guide to the approximate mediolateral position and best frequency of the underlying nucleus laminaris. The dorsal surface of the nucleus magnocellularis was visible at the caudal portion of the hole. Because the size of the cerebellar opening was limited, we were not able to penetrate t ...
Glutamate Inhibits GABA Excitatory Activity in
Glutamate Inhibits GABA Excitatory Activity in

... suggest that GABAergic activity develops early and that glutamate activity occurs soon after. This raises the question as to the possible interaction between the two primary transmitters of the brain during early development. If both GABA and glutamate are excitatory, what prevents the neurons in th ...
Organization of Cortical and Thalamic Input to Pyramidal Neurons in
Organization of Cortical and Thalamic Input to Pyramidal Neurons in

... that are critical for repolarizing the axon. Under these conditions, short laser pulses (1–2 ms) depolarized ChR2-expressing axons in the vicinity of the laser beam and triggered the local release of glutamate. NMDA receptors were blocked (CPP) to sharpen excitatory postsynaptic responses and to pre ...
Mapping Function Onto Neuronal Morphology
Mapping Function Onto Neuronal Morphology

... INTRODUCTION ...
Negatively-Correlated Firing - Department of Computer Science
Negatively-Correlated Firing - Department of Computer Science

... interneurons are very common in the neocortex, and lateral inhibition has been shown to play an important role in sharpening the distinctions between similar inputs, where such inputs would otherwise invoke nearly the same response in neurons with only slightly different response properties. However ...
Electrical stimulation of neural tissue to evoke behavioral responses
Electrical stimulation of neural tissue to evoke behavioral responses

... estimate how far from the electrode tip current activates neural tissue mediating behaviors such as eating (Olds, 1958), self-stimulation (Wise, 1972; Fouriezos and Wise, 1984; Milner and Laferriere, 1986), and circling behavior (Yeomans et al., 1984, 1986). The method used by Fouriezos and Wise (19 ...
The basis of the stress reaction
The basis of the stress reaction

... signals enter the CNS via circumventricular organs3,14. These pathways do not work as ‘soloists’, but the stress projection is in accord with neuronal activation. The humoral signals can affect the CNS in multiple pathways: (i) when the molecule is lipophilic, it can pass freely through the blood–br ...
Topical Review
Topical Review

... specific molecular elements of a growth program to elaborate a growth cone, extend an axon and form new synapses. Nervous system injury also induces glial and meningeal growth-inhibitory proteins that block axonal sprouting.23 The unequivocal demonstration of poststroke axonal sprouting has required ...
Weber et al. - 2000
Weber et al. - 2000

... M-pathway is thought to be concerned primarily with stimulus movement and form, whereas the P-pathway plays a role in the analysis of detail and color vision.2–5 ...
The Neurons of the Medial Geniculate Body in the Mustached Bat
The Neurons of the Medial Geniculate Body in the Mustached Bat

... mustached bats (Pteronotus parnellii). Their somatic and dendritic configurations were compared with those of cells in other, nonecholocating mammals. A second goal was to use the thalamic nuclear subdivisions derived from Golgi material to integrate the findings in parallel studies of cytoarchitect ...
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Axon guidance

Axon guidance (also called axon pathfinding) is a subfield of neural development concerning the process by which neurons send out axons to reach the correct targets. Axons often follow very precise paths in the nervous system, and how they manage to find their way so accurately is being researched.
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