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Volitional enhancement of firing synchrony and oscillation
... occurred in a broad range (approximately 500 μm), and depth of entrained modulation decreased as a function of distance from the operant conditioning sites of electrodes. The study also confirmed that the enhancement of oscillatory activity was not associated with any observed movements or increases ...
... occurred in a broad range (approximately 500 μm), and depth of entrained modulation decreased as a function of distance from the operant conditioning sites of electrodes. The study also confirmed that the enhancement of oscillatory activity was not associated with any observed movements or increases ...
An Integrate-and-fire Model of Prefrontal Cortex Neuronal Activity during Performance of Goal-directed
... The orbitofrontal cortex plays an important role in goaldirected behavior (Wallis et al., 2001). Lesions of the orbitofrontal cortex impair the ability of animals to learn which stimuli are associated with reward (Bechara et al., 1994, 1997; Frey and Petrides, 1997; Miller and Cohen, 2001; Pears et ...
... The orbitofrontal cortex plays an important role in goaldirected behavior (Wallis et al., 2001). Lesions of the orbitofrontal cortex impair the ability of animals to learn which stimuli are associated with reward (Bechara et al., 1994, 1997; Frey and Petrides, 1997; Miller and Cohen, 2001; Pears et ...
CORTICAL PLASTICITY: From Synapses to Maps
... was described in hippocampal CA1 neurons. When presynaptic input from CA3 axons was paired with postsynaptic depolarization, the amplitude of the EPSPs was enhanced. This enhancement was long-lasting and is referred to as LTP (Kelso et al 1986, Malinow & Miller 1986, Sastry et al 1986, Wigström et ...
... was described in hippocampal CA1 neurons. When presynaptic input from CA3 axons was paired with postsynaptic depolarization, the amplitude of the EPSPs was enhanced. This enhancement was long-lasting and is referred to as LTP (Kelso et al 1986, Malinow & Miller 1986, Sastry et al 1986, Wigström et ...
the phase-space dynamics of systems of spiking neurons
... 19th century. Between 1810 and 1819 Franz Joseph Gall published Anatomie et physiologie du systême nerveux en général wherein he propounded the Phrenological Doctrine.1 Functional localization gained empirical support with Paul Broca’s identification of the seat of the faculty of articular speech ...
... 19th century. Between 1810 and 1819 Franz Joseph Gall published Anatomie et physiologie du systême nerveux en général wherein he propounded the Phrenological Doctrine.1 Functional localization gained empirical support with Paul Broca’s identification of the seat of the faculty of articular speech ...
Lateral Connectivity and Contextual Interactions in Macaque
... intrinsic connections but with a peak-to-peak spacing of 0.5 mm (Figure 8E). The other three fully reconstructed V2 injections, two in CO pale stripes and all targeted to highly orientation-specific domains, do not exhibit this degree of clustering (Figure 9B). The 0.5 mm periodicity of the feedback ...
... intrinsic connections but with a peak-to-peak spacing of 0.5 mm (Figure 8E). The other three fully reconstructed V2 injections, two in CO pale stripes and all targeted to highly orientation-specific domains, do not exhibit this degree of clustering (Figure 9B). The 0.5 mm periodicity of the feedback ...
THE PEDUNCULOPONTINE NUCLEUS: Towards a Functional
... neurons. By tracing the projections from the PPN and labelling the cholinergic cells, Semba and colleagues (1990) observed that some of the projection cells, which were negative for ChAT, were located dorsal to the population that were positive for ChAT. In other words, classical targets of the PPN ...
... neurons. By tracing the projections from the PPN and labelling the cholinergic cells, Semba and colleagues (1990) observed that some of the projection cells, which were negative for ChAT, were located dorsal to the population that were positive for ChAT. In other words, classical targets of the PPN ...
Jesús Pujol Martí Neural map organization and development in the lateral-line system
... In particular, I am attempting to understand the mechanisms that govern the communication between sensory organs and the brain. In most sensory systems, neurons project from the sensory receptors to the brain in a spatially ordered manner forming neural maps that encode stimuli attributes, such as i ...
... In particular, I am attempting to understand the mechanisms that govern the communication between sensory organs and the brain. In most sensory systems, neurons project from the sensory receptors to the brain in a spatially ordered manner forming neural maps that encode stimuli attributes, such as i ...
BMC Neuroscience Serial pathways from primate prefrontal cortex to autonomic areas
... which participate in autonomic control (for reviews see [17,18]). In addition, the amygdala issued projections to the same hypothalamic site, revealed by labeled projection neurons in its basal complex, and in the medial, central, and cortical nuclei (Fig. 2F). We confirmed these findings in another ...
... which participate in autonomic control (for reviews see [17,18]). In addition, the amygdala issued projections to the same hypothalamic site, revealed by labeled projection neurons in its basal complex, and in the medial, central, and cortical nuclei (Fig. 2F). We confirmed these findings in another ...
Intracellular and extracellular signatures of action potentials
... work is dedicated to the study of action potential generation, its impact on extracellular field and local network establishment. We considered three questions: Firstly, (i) we asked why mammalian neurons often have characteristically sharp onset in the somatic recordings of action potentials. Until ...
... work is dedicated to the study of action potential generation, its impact on extracellular field and local network establishment. We considered three questions: Firstly, (i) we asked why mammalian neurons often have characteristically sharp onset in the somatic recordings of action potentials. Until ...
Laminar Selectivity of the Cholinergic Suppression of Synaptic
... synaptic transmissionat excitatory intrinsic synapses between pyramidal cells, while having little effect on synaptic transmission at afferent fibers arising from the olfactory bulb (Hasseimoand Bower, 1992).In modelsofpiriform cortex (Hasselmo et al., 1992; Barkai and Hasselmo, 1994a,b; Hasselmo, 1 ...
... synaptic transmissionat excitatory intrinsic synapses between pyramidal cells, while having little effect on synaptic transmission at afferent fibers arising from the olfactory bulb (Hasseimoand Bower, 1992).In modelsofpiriform cortex (Hasselmo et al., 1992; Barkai and Hasselmo, 1994a,b; Hasselmo, 1 ...
mTOR pathway – novel modulator of astrocyte activity.
... synthetase (iNOS) can be induced in different cell types and tissues by exposure to immunological and inflammatory stimuli (KLEINERT et al. 2004). In vitro study confirmed that primary astrocyte cultures express iNOS in response to cytokines such as IL-1â (CHASTRE et al. 2010), interferon ã (IFNã), ...
... synthetase (iNOS) can be induced in different cell types and tissues by exposure to immunological and inflammatory stimuli (KLEINERT et al. 2004). In vitro study confirmed that primary astrocyte cultures express iNOS in response to cytokines such as IL-1â (CHASTRE et al. 2010), interferon ã (IFNã), ...
Hypothalamus
... However, the parvocellular neurons release their secretory products into fenestrated capillaries that drain into the long portal vessels that drain into the anterior lobe. The magnocellular neurons secrete either vasopressin or oxytocin, and are largely concentrated in the supraoptic (SON) and parav ...
... However, the parvocellular neurons release their secretory products into fenestrated capillaries that drain into the long portal vessels that drain into the anterior lobe. The magnocellular neurons secrete either vasopressin or oxytocin, and are largely concentrated in the supraoptic (SON) and parav ...
Different levels of Ih determine distinct temporal integration in
... behaviour. Although this classification into two neuronal classes is well described, it is unknown how these two classes of neurons contribute to the integration of input to the subiculum. Here, we report that bursting neurons posses a hyperpolarization-activated cation current (I h ) that is two-fo ...
... behaviour. Although this classification into two neuronal classes is well described, it is unknown how these two classes of neurons contribute to the integration of input to the subiculum. Here, we report that bursting neurons posses a hyperpolarization-activated cation current (I h ) that is two-fo ...
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia
... adenosine A2A receptor (22). Furthermore, an interaction between NECAB2 and metabotropic glutamate receptor 5 (mGluR5) was demonstrated in rat hippocampal pyramidal cells, possibly regulating mGluR5’s coupling to its signaling machinery (26). Significance Calcium-binding proteins (CaBPs) are key det ...
... adenosine A2A receptor (22). Furthermore, an interaction between NECAB2 and metabotropic glutamate receptor 5 (mGluR5) was demonstrated in rat hippocampal pyramidal cells, possibly regulating mGluR5’s coupling to its signaling machinery (26). Significance Calcium-binding proteins (CaBPs) are key det ...
Nerve Growth Factor: Cellular localization and regulation of synthesis
... I Max-Planck.Instilute Cor Psychialry, Oeparlmeol of Neu rochemi$uy, 0-8033 Marti nsricd, FRQ. 2To whom oorrespondence should be addressed. ...
... I Max-Planck.Instilute Cor Psychialry, Oeparlmeol of Neu rochemi$uy, 0-8033 Marti nsricd, FRQ. 2To whom oorrespondence should be addressed. ...
Thyroid Hormone Controls the Onset of Androgen Sensitivity in the
... randomly assigned to one of three experimental groups: 0.01% 6n-propyl-2-thiouracil (PTU, Sigma), 0.01% PTU and 0.025 mg/liter dihydrotestosterone (5a-androstan-17b-ol-3-one; DHT, Sigma), or were reared as untreated controls. DHT was solubilized in ethanol (50 ml per liter of tank water); to control ...
... randomly assigned to one of three experimental groups: 0.01% 6n-propyl-2-thiouracil (PTU, Sigma), 0.01% PTU and 0.025 mg/liter dihydrotestosterone (5a-androstan-17b-ol-3-one; DHT, Sigma), or were reared as untreated controls. DHT was solubilized in ethanol (50 ml per liter of tank water); to control ...
Neurons in red nucleus and primary motor cortex exhibit similar
... Primary motor cortex (M1) and red nucleus (RN) are brain regions involved in limb motor control. Both structures are highly interconnected with the cerebellum and project directly to the spinal cord, although the contribution of RN is smaller than M1. It remains uncertain whether RN and M1 serve sim ...
... Primary motor cortex (M1) and red nucleus (RN) are brain regions involved in limb motor control. Both structures are highly interconnected with the cerebellum and project directly to the spinal cord, although the contribution of RN is smaller than M1. It remains uncertain whether RN and M1 serve sim ...
Oxytocin Influence on the Nucleus of the Solitary Tract
... but remained resistant to oxytocin actions. Thus, selective modulation of the NTS is achieved via variation in the oxytocin responsiveness of the second order NTS neurons and heterogeneous innervation by oxytocin-containing axons projecting from the paraventricular nucleus. The study includes a brie ...
... but remained resistant to oxytocin actions. Thus, selective modulation of the NTS is achieved via variation in the oxytocin responsiveness of the second order NTS neurons and heterogeneous innervation by oxytocin-containing axons projecting from the paraventricular nucleus. The study includes a brie ...
Critical role of extracellularly secreted neuronal pentraxin 1 in
... disabilities in surviving infants and children. Previously we reported induction of neuronal pentraxin 1 (NP1) in hypoxic-ischemic injury in neonatal brain and NP1 co-localization with the excitatory AMPA receptors GluR1 at the synaptic sites. However, how NP1 contributes to hypoxic-ischemic neurona ...
... disabilities in surviving infants and children. Previously we reported induction of neuronal pentraxin 1 (NP1) in hypoxic-ischemic injury in neonatal brain and NP1 co-localization with the excitatory AMPA receptors GluR1 at the synaptic sites. However, how NP1 contributes to hypoxic-ischemic neurona ...
electrophysiological studies of rat substantia nigra neurons in an in
... Although the precise mechanism of delayed neuronal degeneration in the SNR following MCA occlusion is not known, there is increasing evidence that the excessive excitation induced by a loss of an inhibitory GABAergic input from the neostriatum and/or the globus pallidus plays a major role. The delay ...
... Although the precise mechanism of delayed neuronal degeneration in the SNR following MCA occlusion is not known, there is increasing evidence that the excessive excitation induced by a loss of an inhibitory GABAergic input from the neostriatum and/or the globus pallidus plays a major role. The delay ...
On the Role of the Pontine Brainstem in Vocal Pattern Generation: A
... call specificity, and pre-vocal onset time. Statistical analyses were performed for the syllable pre-onset times by a univariate variance analysis (general linear model) comparing general Figure 2. Frontal sections of the squirrel monkey’s brainstem at the midbrain-pons transition (stereotaxic coord ...
... call specificity, and pre-vocal onset time. Statistical analyses were performed for the syllable pre-onset times by a univariate variance analysis (general linear model) comparing general Figure 2. Frontal sections of the squirrel monkey’s brainstem at the midbrain-pons transition (stereotaxic coord ...
Modulation of Inhibitory Synaptic Potentials in the Piriform Cortex
... (Hasselmo and Linster 1998a,b; Hasselmo et al. 1997), hippocampus (Hasselmo et al. 1995; Tsodyks et al. 1997), somatosensory cortex (Pinto et al. 1996), and visual cortex (Hansel and Sompolinsky 1998). These models leave out many of the details incorporated in compartmental biophysical simulations ( ...
... (Hasselmo and Linster 1998a,b; Hasselmo et al. 1997), hippocampus (Hasselmo et al. 1995; Tsodyks et al. 1997), somatosensory cortex (Pinto et al. 1996), and visual cortex (Hansel and Sompolinsky 1998). These models leave out many of the details incorporated in compartmental biophysical simulations ( ...
"Sleep and Memory". In: Encyclopedia of Life Sciences (ELS)
... Figure 2 Potential roles of sleep in synaptic and systems consolidation. (a) Representative changes in release of acetylcholine (ACh) and noradrenaline (NA) in the cortex (relative to waking) during REM and NREM sleep. Representative EEG traces for the two sleep states show cortical activity similar ...
... Figure 2 Potential roles of sleep in synaptic and systems consolidation. (a) Representative changes in release of acetylcholine (ACh) and noradrenaline (NA) in the cortex (relative to waking) during REM and NREM sleep. Representative EEG traces for the two sleep states show cortical activity similar ...
Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce
... activity. Slow-wave sleep consisted of high-amplitude slow waves together with a low EMG tone relative to waking. REM sleep was identified by the presence of desynchronized EEG and /or activity coupled with low EMG relative to slow-wave sleep. The amount of time spent in wakef ulness, SWS, and REM ...
... activity. Slow-wave sleep consisted of high-amplitude slow waves together with a low EMG tone relative to waking. REM sleep was identified by the presence of desynchronized EEG and /or activity coupled with low EMG relative to slow-wave sleep. The amount of time spent in wakef ulness, SWS, and REM ...