FORMULATION AND OPTIMIZATION OF OCULAR POLY-D, L-LACTIC ACID NANO DRUG
... Designing of dosage form with the minimum number of trials is very crucial for the pharmaceutical researchers. Statistical experimental designs are powerful, efficient and systematic tools in the design of pharmaceutical dosage forms, allowing a rational study of the influence of formulation and/or ...
... Designing of dosage form with the minimum number of trials is very crucial for the pharmaceutical researchers. Statistical experimental designs are powerful, efficient and systematic tools in the design of pharmaceutical dosage forms, allowing a rational study of the influence of formulation and/or ...
FORMULATION AND EVALUATION OF BILAYER BUCCAL TABLET OF SUMATRIPTAN SUCCINATE Original Article
... Buccal delivery of drug, as an alternative to the oral route of drug administration, is a subject of growing interest because of its numerous advantages such as good accessibility, robustness of epithelium, facile removal of dosage form in case of need, relatively low enzymatic activity, prevent dru ...
... Buccal delivery of drug, as an alternative to the oral route of drug administration, is a subject of growing interest because of its numerous advantages such as good accessibility, robustness of epithelium, facile removal of dosage form in case of need, relatively low enzymatic activity, prevent dru ...
local drug delivery systems in the treatment of
... mechanism controlling drug release. We distinguish three categories: (i) Solvent controlled' matrix systems based on macromolecular matrix permeability to small molecules after matrix swelling into hydrated medium; (ii) Reservoir systems' controlled by drug diffusion across a polymeric membrane; (ii ...
... mechanism controlling drug release. We distinguish three categories: (i) Solvent controlled' matrix systems based on macromolecular matrix permeability to small molecules after matrix swelling into hydrated medium; (ii) Reservoir systems' controlled by drug diffusion across a polymeric membrane; (ii ...
FORMULATION DEVELOPMENT, OPTIMIZATION AND IN-VITRO RELEAS KINETIC STUDY ON
... Oral delivery of drugs in the colon is valuable in the treatment of diseases [1] of colon like colon cancer, diarrhea, inflammation, constipation, crohn’s disease etc where by high local concentration can be achieved while minimizing side effects. The colon is attracting interest as a site where poo ...
... Oral delivery of drugs in the colon is valuable in the treatment of diseases [1] of colon like colon cancer, diarrhea, inflammation, constipation, crohn’s disease etc where by high local concentration can be achieved while minimizing side effects. The colon is attracting interest as a site where poo ...
Buccal Drug Delivery Systems: Opportunities And Challenges In Buccal,
... totalled approximately $1.3 billion in the U.S. while the total market grew to more than $1.7 billion, driven by a 11 percent increase in prescriptions. In 2014, Bunavail buccal film has received US approval which has similar bioavailability of suboxone with half of the dose of buprenorphine. Other ...
... totalled approximately $1.3 billion in the U.S. while the total market grew to more than $1.7 billion, driven by a 11 percent increase in prescriptions. In 2014, Bunavail buccal film has received US approval which has similar bioavailability of suboxone with half of the dose of buprenorphine. Other ...
International Journal Of Pharma Professional`s Research RECENT
... delivery of interferon (IFN) α, an antiviral agent that thinner skin has significant effects on the pharmacokinetics of used to treat condylomata acuminata (genital warts) is transdermal delivery for children. In some situations this may be administered by using lipid-based delivery systems an advan ...
... delivery of interferon (IFN) α, an antiviral agent that thinner skin has significant effects on the pharmacokinetics of used to treat condylomata acuminata (genital warts) is transdermal delivery for children. In some situations this may be administered by using lipid-based delivery systems an advan ...
FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF Research Article
... release formulations. The guar gum was utilized in the formulation of matrix tablets containing Flurbiprofen by wet granulation technique and evaluated for drug release characteristics. Formulation was optimized on the basis of acceptable tablet properties (hardness, friability, drug content and wei ...
... release formulations. The guar gum was utilized in the formulation of matrix tablets containing Flurbiprofen by wet granulation technique and evaluated for drug release characteristics. Formulation was optimized on the basis of acceptable tablet properties (hardness, friability, drug content and wei ...
IMPROVEMENT IN BIOAVAILABILITY OF CLASS-III DRUG: PHYTOLIPID DELIVERY SYSTEM Review Article
... Mechanism of phytophospholipid Complex formation The poor absorption of flavonoid nutrients is likely due to two main factors. First, these are multiple ring molecules not quite small enough to be absorbed from the intestine into the blood by simple diffusion, nor does the intestinal lining actively ...
... Mechanism of phytophospholipid Complex formation The poor absorption of flavonoid nutrients is likely due to two main factors. First, these are multiple ring molecules not quite small enough to be absorbed from the intestine into the blood by simple diffusion, nor does the intestinal lining actively ...
Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms
... extrudate to spheroids of uniform size; drying; sifting to achieve the desired size distribution and coating (optional). In the wet masses comprising SES (polysorbate 80 and mono-/ di-glycerides), lactose, water and MCC, the relative quantities of SES and water had a significant effect on the extrus ...
... extrudate to spheroids of uniform size; drying; sifting to achieve the desired size distribution and coating (optional). In the wet masses comprising SES (polysorbate 80 and mono-/ di-glycerides), lactose, water and MCC, the relative quantities of SES and water had a significant effect on the extrus ...
Effect of drug type on the degradation rate of PLGA
... Kiortsis et al. [18] have shown that the % release of drugs from cellulosic polymers, at a fixed time point, depends on the drug solubility in water; it seems reasonable that hydrophilic drugs with high solubility may increase the rate of water diffusion into the matrix, thereby accelerating release ...
... Kiortsis et al. [18] have shown that the % release of drugs from cellulosic polymers, at a fixed time point, depends on the drug solubility in water; it seems reasonable that hydrophilic drugs with high solubility may increase the rate of water diffusion into the matrix, thereby accelerating release ...
CHEMICAL STABILITY STUDIES OF BIOADHESIVE TOPICAL GEL Research Article LALIT KUMAR
... In–vitro drug permeation study of bntgs: The invitro drug permeation study of topical gel through the hairless goat skin membrane was performed using a Keshary‐Chien (KC) type glass diffusion cell at 37±2°C. Fresh hairless goat skin membrane was mounted between donor an ...
... In–vitro drug permeation study of bntgs: The invitro drug permeation study of topical gel through the hairless goat skin membrane was performed using a Keshary‐Chien (KC) type glass diffusion cell at 37±2°C. Fresh hairless goat skin membrane was mounted between donor an ...
TRANSDERMAL PATCHES: A RECENT APPROCH TO NEW DRUG DELIVERY SYSTEM
... transport of the parent drug in the stratum corneum. Upon reaching the viable epidermis, esterases release the parent drug by hydrolysis thereby optimising solubility in the aqueous epidermis. For example: The intrinsic poor permeability of the very polar 6mercaptopurine was increased up to 240 time ...
... transport of the parent drug in the stratum corneum. Upon reaching the viable epidermis, esterases release the parent drug by hydrolysis thereby optimising solubility in the aqueous epidermis. For example: The intrinsic poor permeability of the very polar 6mercaptopurine was increased up to 240 time ...
Put Paper Title Here
... modification to the process can have impacts on the fuel design, amount of waste generated by the process, number of cycles through the reactor, etc. In a nuclear growth scenario, the introduction of advanced thermal reactor designs will almost certainly result in changes in separations system requi ...
... modification to the process can have impacts on the fuel design, amount of waste generated by the process, number of cycles through the reactor, etc. In a nuclear growth scenario, the introduction of advanced thermal reactor designs will almost certainly result in changes in separations system requi ...
a new graduate course teaching chemical engineering in use
... oriented assignments and student presentation. The case studies are closely combined with the research work of the students. The course has been welcomed not only by the graduate students from this department but also those from other departments and colleges. Keywords; engineering education, renewa ...
... oriented assignments and student presentation. The case studies are closely combined with the research work of the students. The course has been welcomed not only by the graduate students from this department but also those from other departments and colleges. Keywords; engineering education, renewa ...
Full Article - Pharmascope.org
... been estimated 3-8 days compared to about 30 days for the skin which may change permeability characteristics frequently (Gandhi R.B et al., 1994). Theories of mucoadhesion The most widely investigated group of mucoadhesives used in buccal drug delivery systems are hydrophilic macromolecules containi ...
... been estimated 3-8 days compared to about 30 days for the skin which may change permeability characteristics frequently (Gandhi R.B et al., 1994). Theories of mucoadhesion The most widely investigated group of mucoadhesives used in buccal drug delivery systems are hydrophilic macromolecules containi ...
AS A NEWER VENTURE IN FAST DISSOLVING DOSAGE FORMS
... being slightly lower for the former than for some ...
... being slightly lower for the former than for some ...
1 Anish et al Journal of Drug Delivery & Therapeutics; 2012, 2(1)
... Light sensitive hydrogels have potential application in developing optical switches, display units, and ophthalmic drug delivery devices. Since the light stimulus can be impose instantly and delivered in specific amounts with high accuracy, light sensitive hydrogels may posses special advantage over ...
... Light sensitive hydrogels have potential application in developing optical switches, display units, and ophthalmic drug delivery devices. Since the light stimulus can be impose instantly and delivered in specific amounts with high accuracy, light sensitive hydrogels may posses special advantage over ...
Transdermal Drug Delivery Market & Clinical Pipeline Insight Brochure
... of the skin. The major underlying factor driving this method is that the human skin is the most readily accessible surface for the delivery of drugs. A transdermal patch is defined as a medicated adhesive patch which is placed on the skin for delivering a specific dose of medication through the laye ...
... of the skin. The major underlying factor driving this method is that the human skin is the most readily accessible surface for the delivery of drugs. A transdermal patch is defined as a medicated adhesive patch which is placed on the skin for delivering a specific dose of medication through the laye ...
PERCUTANEOUS DRUG DELIVERY SYSTEMS FOR IMPROVING ANTIFUNGAL THERAPY EFFECTIVENESS: A REVIEW
... only the ones related with fungi but also with Leishmania parasites that grow in skin layers. Azoles are the most commonly used antifungals in clinical treatment of superficial fungal infections, but their physicochemical properties limit their bioavailability; consequently most of the azoleloaded d ...
... only the ones related with fungi but also with Leishmania parasites that grow in skin layers. Azoles are the most commonly used antifungals in clinical treatment of superficial fungal infections, but their physicochemical properties limit their bioavailability; consequently most of the azoleloaded d ...
Transdermal Patches a successful tool in Transdermal
... of a major index of the system performance versus time). All transdermal systems consist of four essential parts, a sub-system that transmits system energy to those locations where it is required for performance, a control system that monitors and controls system functioning, the part (or parts) tha ...
... of a major index of the system performance versus time). All transdermal systems consist of four essential parts, a sub-system that transmits system energy to those locations where it is required for performance, a control system that monitors and controls system functioning, the part (or parts) tha ...
sustained release matrix type drug delivery system: a review
... pharmacokinetics and Pharmacodynamic properties of drugs in such a way that it reduce dosing frequency to an extent that once daily dose is sufficient for penetration, polymer swelling, drug dissolution, drug diffusion and matrix erosion. Highly water soluble drugs like Diltiazem; Ranitidine has bee ...
... pharmacokinetics and Pharmacodynamic properties of drugs in such a way that it reduce dosing frequency to an extent that once daily dose is sufficient for penetration, polymer swelling, drug dissolution, drug diffusion and matrix erosion. Highly water soluble drugs like Diltiazem; Ranitidine has bee ...
PHARMACEUTICAL ASPECTS OF NICORANDIL
... the drug for the predetermined time with minimal fluctuations. Nicorandil is a potential drug candidate to develop as transdermal therapeutic system after predicting its permeation across human skin based on its in vitro permeation through animal skin model26, 27. Develo ...
... the drug for the predetermined time with minimal fluctuations. Nicorandil is a potential drug candidate to develop as transdermal therapeutic system after predicting its permeation across human skin based on its in vitro permeation through animal skin model26, 27. Develo ...
10. review of literature
... kinetic models and found that the drug release follow zero order kinetics. 2.1.4. Gupta et al., 2010 have worked on osmotically controlled drug delivery system with associated drugs that can be delivered in a controlled pattern over a long period of time by the controlled or modified release drug de ...
... kinetic models and found that the drug release follow zero order kinetics. 2.1.4. Gupta et al., 2010 have worked on osmotically controlled drug delivery system with associated drugs that can be delivered in a controlled pattern over a long period of time by the controlled or modified release drug de ...
oral controlled release drug delivery system
... delivered in small intestine and is being subjected to more degradation 8-10. Molecular size and diffusivity Diffusivity depends on size and shape of the cavities of the membrane 7. The diffusion co-efficient of intermediate molecular weight drug is 100-400 Daltons; through flexible polymer range is ...
... delivered in small intestine and is being subjected to more degradation 8-10. Molecular size and diffusivity Diffusivity depends on size and shape of the cavities of the membrane 7. The diffusion co-efficient of intermediate molecular weight drug is 100-400 Daltons; through flexible polymer range is ...
Oral Extended Release Drug Delivery System: A Promising Approach
... slowly into the GIT and maintain a constant drug Extended release drug delivery system achieves a slow release of the drug over an extended period of time or the concentration in the plasma for a longer period of time.7 drug is absorbed over a longer period of time. Extended release dosage form init ...
... slowly into the GIT and maintain a constant drug Extended release drug delivery system achieves a slow release of the drug over an extended period of time or the concentration in the plasma for a longer period of time.7 drug is absorbed over a longer period of time. Extended release dosage form init ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.