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Cardiovascular Drug Delivery - Technologies, Markets and Companies Brochure
Cardiovascular Drug Delivery - Technologies, Markets and Companies Brochure

... Drugs can be introduced into the vascular system for systemic effects or targeted to an organ via the regional blood supply. In addition to the usual formulations of drugs such as controlled release, devices are used as well. This report starts with an introduction to molecular cardiology and discus ...
IN SITU OF PILOCARPINE Research Article
IN SITU OF PILOCARPINE Research Article

... Department of Pharmaceutics, JSS College of Pharmacy, JSS University, Sri Shivarathreeshwara Nagar, Mysore-570015, Karnataka, India. Email: [email protected] Received: 11 Oct 2012, Revised and Accepted: 21 Nov 2012 ABSTRACT Several ophthalmic delivery systems have been developed to prolong the ...
PHYTOSOMES: A NOVEL DOSAGE FORM FOR ENHANCEMENT OF BIOAVAILABILITY OF  BOTANICALS AND NEUTRACEUTICALS Review Article   
PHYTOSOMES: A NOVEL DOSAGE FORM FOR ENHANCEMENT OF BIOAVAILABILITY OF  BOTANICALS AND NEUTRACEUTICALS Review Article   

... The  advancement  in  the  field  of  herbal  drug  delivery  started  recently  with  the  aim  to  manage  human  diseases  efficiently.  Every  nation  is  seeking  health  care  beyond  the  traditional  boundaries  of  modern  medicine;  turning  to  self  medication  in  the  form  of  herbal  ...
DESIGN AND OPTIMISATION OF EXTENDED RELEASE METOPROLOL SUCCINATE
DESIGN AND OPTIMISATION OF EXTENDED RELEASE METOPROLOL SUCCINATE

... formulation scientist. This challenge can be attributed to key factors like high water solubility of drug leading to burst release, lack of control over polymer relaxation/disentanglement related to drug dissolution and diffusion, compensation for an increase in the diffusional path length which is ...
Sample pages 1 PDF
Sample pages 1 PDF

... century was a breakthrough with historic medical and social consequences, it is recognized that there is substantial room for improvement. Daily oral dosing can lead to incomplete compliance and effectiveness, so other routes have been studied. For example, a transdermal, patch-based contraceptive s ...
ASYMMETRIC MEMBRANE CAPSULE (AMC): AN USEFUL OSMOTIC DRUG DELIVERY SYSTEM
ASYMMETRIC MEMBRANE CAPSULE (AMC): AN USEFUL OSMOTIC DRUG DELIVERY SYSTEM

... LALIT KUMAR*1, SHIVANI1, ANKUSH KUMAR1, DEEPA PARASHAR1, SULEKHA BHADRA1 1.Department ...
Design and evaluation of edible gels of alendronate ISSN:2320-2831
Design and evaluation of edible gels of alendronate ISSN:2320-2831

... tablets, capsules, and liquids, which are used orally, are difficult to swallow in case of dysphagia patients 3,4. Patients with advanced age cannot easily take tablets or capsules. The irritation or pain resulting from the contact of the solid preparation with the oral cavity or with the larynx and ...
poly(lactic-co-glycolic acid) based drug delivery devices
poly(lactic-co-glycolic acid) based drug delivery devices

... has been approved by FDA (Food and Drug Administration). Numerous active pharmaceutical ingredients such as anticancer drugs, analgesics, antibiotics and macromolecular drugs such as proteins, peptides, genes, vaccines, antigens, human growth factors, vascular endothelial growth factors etc., are su ...
CRS Newsletter. Volume 25, Number 2. 2008
CRS Newsletter. Volume 25, Number 2. 2008

... ver the past year the CRS Board of Directors has developed a new CRS strategic plan that specifies goals and objectives, along with current priorities for achieving these objectives. I would like to highlight some of our activities and the progress that has been made on some of the strategic initiat ...
booklet internal pages
booklet internal pages

... Results: Digestion of ICG nanoparticles with cathepsin B resulted in alteration of the mean particle size and a significant increase in ICG cellular uptake. ICG-nanoparticle uptake and toxicity in the absence laser light were minimal. Treatment with laser light resulted in 9%, 37% and 47% cell toxic ...
bioavailability enhancdement of poorly soluble drugs by smedds
bioavailability enhancdement of poorly soluble drugs by smedds

... approach is that pre-dissolving the compound overcomes the initial rate limiting step of particulate dissolution in the aqueous environment within the GI tract. However, a potential problem is that the drug may precipitate out of solution when the formulation disperses in the GI tract, particularly ...
CONVENTIONAL AND NOVEL APPROACHES FOR COLON - e-JST
CONVENTIONAL AND NOVEL APPROACHES FOR COLON - e-JST

... colitis), irritable bowel syndrome and colon cancer. Other potential applications of colonic delivery include chronotherapy, prophylaxis of colon cancer and treatment of nicotine addiction1,2. The most critical challenge in such drug delivery approach is to preserve the formulation and also preserve ...
FORMULATION AND EVALUATION OF FLOATING CONTROLLED RELEASE TABLETS OF
FORMULATION AND EVALUATION OF FLOATING CONTROLLED RELEASE TABLETS OF

... shown there was no interaction between drug and polymers. The percentage of Imatinib Mesylate content from the tablets was determined by UVSpectroscopy and ranged from 98.25±1.8 to 98.91±1.5. The in-vitro percentage release of Imatinib Mesylate from the optimized tablets at the end of 12 hours was 9 ...
Formulation Design and Characterization of Kollidon SR Based
Formulation Design and Characterization of Kollidon SR Based

... short half-lives as well as to increase patient compliance. These formulations are designed to deliver drugs at a predetermined rate over a wide range of conditions and durations of therapeutic treatments. One of the most commonly used methods of developing sustained release formulations for therape ...
Photopolymerizable hydrogels for tissue engineering
Photopolymerizable hydrogels for tissue engineering

... as cell carrier materials for tissue replacement strategies. Hydrogels as barriers. Photopolymerized hydrogels have been investigated for use as barriers following tissue injury in order to improve the healing response. These applications have included the prevention of thrombosis and restenosis fol ...
FORMULATION AND EVALUATION OF GUM OLIBANUM­BASED SUSTAINED RELEASE MATRIX  TABLETS OF AMBROXOL HYDROCHLORIDE
FORMULATION AND EVALUATION OF GUM OLIBANUM­BASED SUSTAINED RELEASE MATRIX  TABLETS OF AMBROXOL HYDROCHLORIDE

... uniformity, uniform thickness and low friability. The results of in vitro dissolution studies indicated that all the formulations exhibited good drug  release  pattern.  The  data  was  fitted  to  various  kinetic  models  to  know  the  mechanism  of  drug  release.  The  optimized  Ambroxol  hydr ...
Sustained Release Drug Delivery System Potential
Sustained Release Drug Delivery System Potential

... Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimizing side effects. Oral drug delivery system represents one of the frontier areas of controlled drug delivery system. Such a dosage forms having a major adva ...
orodispersible_dosage_forms
orodispersible_dosage_forms

... low to allow for microbial growth. A major claim of the Zydis product is increased bioavailability compared to traditional tablets. Because of its dispersion and dissolution in saliva while still in the oral cavity, there can be a substantial amount of pregastric absorption from this formulation. Bu ...
Calandopharma
Calandopharma

... The study was led by Professor Mark E. Davis and a team of scientists at Caltech. It also included researchers and clinicians from UCLA and South Texas Accelerated Research Therapeutics (START), the two sites conducting Calando’s clinical trial. The trial, which is investigating the safety and effi ...
File - Sourav Sarkar
File - Sourav Sarkar

... • Bioavailability of curcumin: problems and promises. P Anand, AB Kunnumakkara, RA Newman, BB Aggarwal, Mol. Pharm, 4(6); 807, 2007 • Curcumin: the Indian solid gold. BB Aggarwal, C Sundaram, N Malani, H Ichikawa, Springer US, 2007 ...
transcutaneous drug delivery system: a comprehensive review
transcutaneous drug delivery system: a comprehensive review

... Sandhu Premjeet1,2*, Kataria Sahil1, Bilandi Ajay1 , Jain Sonam2, Rathore Devashish2 ...
Chemical Properties - Michigan State University
Chemical Properties - Michigan State University

... revamp my next lesson to clear up any misconceptions. I think if students don’t understand the science behind chemical and physical changes, they wont really understand the concept. Knowing that chemical reactions produce a chemical change is pretty important. Its also very important that the studen ...
LOCAL DRUG DELIVERY IN PERIODONTICS: A STRATEGIC INTERVENTION Review Article
LOCAL DRUG DELIVERY IN PERIODONTICS: A STRATEGIC INTERVENTION Review Article

... periodontal diseases. It can be noted that only a limited number of antimicrobial agents have been used so far in formulations of local delivery systems. There are distinct phases in a periodontal treatment plan where a dental practitioner can use a sustained release device. It can be used as an adj ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... cure was not yet discovered. Medications for treating immune responses are of main use for chronic arthritis patients but inflammat ion conditions can only be treated by NSAIDS, which g ives symptomatic relief. Though it will not cure the disease it will be a necessary adjunctive therapy for symptom ...
fast dissolving films - Asian Journal of Pharmaceutical Science and
fast dissolving films - Asian Journal of Pharmaceutical Science and

... Pandya Ketul*, K.R. Patel, M.R. Patel, N.M. Patel Department of Pharmaceutics, Shri B.M.Shah College of Pharmaceutical Education and Research, Modasa. ABSTRACT In the recent years, many of the pharmaceutical groups are focusing their research on rapid dissolving technology. This technology evolved o ...
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Nicholas A. Peppas



Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.
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