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... Transporters and efflux systems Physicochemical properties of drugs Molecular weight Lipophilicity ...
... Transporters and efflux systems Physicochemical properties of drugs Molecular weight Lipophilicity ...
Review Article TRANSDERMAL DRUG DELIVERY SYSTEM
... Should be compatible with transdermal system as remain in use while applying. ...
... Should be compatible with transdermal system as remain in use while applying. ...
Chemical Process Modeling in Modelica
... Chemical Process Modeling in Modelica Ali Baharev Arnold Neumaier Fakultät für Mathematik, Universität Wien Nordbergstraße 15, A-1090 Wien, Austria ...
... Chemical Process Modeling in Modelica Ali Baharev Arnold Neumaier Fakultät für Mathematik, Universität Wien Nordbergstraße 15, A-1090 Wien, Austria ...
OPTIMIZATION AND EVALUATION OF CIPROFLOXACIN SWELLABLE FLOATING MATRIX
... and dosage form characteristics.1,2 Most of the oral dosage forms possess several physiological limitations such as variable gastrointestinal transit, because of variable gastric emptying leading to non-uniform absorption profiles, incomplete drug release and shorter residence time of the dosage for ...
... and dosage form characteristics.1,2 Most of the oral dosage forms possess several physiological limitations such as variable gastrointestinal transit, because of variable gastric emptying leading to non-uniform absorption profiles, incomplete drug release and shorter residence time of the dosage for ...
PLGA-Alendronate Conjugate as a New Biomaterial
... as a New Biomaterial to Produce Osteotropic Drug Nanocarriers Rosario Pignatello Department of Pharmaceutical Sciences Faculty of Pharmacy, University of Catania Italy 1. Introduction Targeting bone tissue to treat specific diseases, such as primary tumour or bone metastases from peripheral malignan ...
... as a New Biomaterial to Produce Osteotropic Drug Nanocarriers Rosario Pignatello Department of Pharmaceutical Sciences Faculty of Pharmacy, University of Catania Italy 1. Introduction Targeting bone tissue to treat specific diseases, such as primary tumour or bone metastases from peripheral malignan ...
Document
... 1 University “Goce Delchev”- Stip, Faculty of medical sciences 2 Faculty of Pharmacy, Medical University of Sofia, 2 Dunav St., 1000 Sofia, Bulgaria 3 Institute of Polymers, Bulgarian Academy of Sciences, 103 Acad. Georgi Bonchev St., 1113 Sofia, Bulgaria E-mail: [email protected] ...
... 1 University “Goce Delchev”- Stip, Faculty of medical sciences 2 Faculty of Pharmacy, Medical University of Sofia, 2 Dunav St., 1000 Sofia, Bulgaria 3 Institute of Polymers, Bulgarian Academy of Sciences, 103 Acad. Georgi Bonchev St., 1113 Sofia, Bulgaria E-mail: [email protected] ...
Pobierz plik
... 80, ethanol and oleic acid. Four different formulations were prepared. Pseudoternary diagram was constructed, in which shaded area represents the microemulsion range whereas non shaded area represents unclear range. Phase diagrams were used to determine concentrations required to prepare microemulsi ...
... 80, ethanol and oleic acid. Four different formulations were prepared. Pseudoternary diagram was constructed, in which shaded area represents the microemulsion range whereas non shaded area represents unclear range. Phase diagrams were used to determine concentrations required to prepare microemulsi ...
IN SITU Research Article SANTHOSH KUMAR.J*
... and to improve the therapeutic efficacy by formulating cytarabine an subcutaneous in situ implants for at least 30 days. Cytarabine in situ implants were prepared by polymer precipitation method using two different grades of polymer PLGA with three different concentrations. This system is prepared b ...
... and to improve the therapeutic efficacy by formulating cytarabine an subcutaneous in situ implants for at least 30 days. Cytarabine in situ implants were prepared by polymer precipitation method using two different grades of polymer PLGA with three different concentrations. This system is prepared b ...
STUDIES ON FORMULATION AND EVALUATION OF OSMOTICALLY CONTROLLED DRUG Research Article
... frequency and side effects. As new innovation in oral controlled plasma drug delivery it avoids fluctuation in drug concentration and offers better drug utilization and patient compliance. So in the present study attempt has been made to control the release of Carbamazepine by two different approach ...
... frequency and side effects. As new innovation in oral controlled plasma drug delivery it avoids fluctuation in drug concentration and offers better drug utilization and patient compliance. So in the present study attempt has been made to control the release of Carbamazepine by two different approach ...
An approach to bypass the blood brain barrier
... brain.27-29 The intraneuronal pathway involves axonal transport and requires hours to days for drugs to reach different brain regions. While the extraneuronal pathway probably relies on bulk flow transport through perineural channels, which deliver drugs directly to the brain parenchymal tissue and/ ...
... brain.27-29 The intraneuronal pathway involves axonal transport and requires hours to days for drugs to reach different brain regions. While the extraneuronal pathway probably relies on bulk flow transport through perineural channels, which deliver drugs directly to the brain parenchymal tissue and/ ...
Principles of Metered-Dose Inhaler Design
... the propellant mixture, the presence of other excipients (surfactants and other inactive components of the formulation), and ambient temperature. Recently, the use of CFCs was banned under international agreement, because the release of chlorine during their degradation damages the ozone layer in th ...
... the propellant mixture, the presence of other excipients (surfactants and other inactive components of the formulation), and ambient temperature. Recently, the use of CFCs was banned under international agreement, because the release of chlorine during their degradation damages the ozone layer in th ...
Osmotic-Controlled Release Oral Delivery System
... ingredient, osmotic delivery systems can be classified as follows: 1. Osmotic delivery systems for solids a. Type I: Single compartment. In this design, the drug and the osmotic agent are located in the same compartment and are surrounded by the semipermeable membrane (SPM). Both the core components ...
... ingredient, osmotic delivery systems can be classified as follows: 1. Osmotic delivery systems for solids a. Type I: Single compartment. In this design, the drug and the osmotic agent are located in the same compartment and are surrounded by the semipermeable membrane (SPM). Both the core components ...
Fabrication and Evaluation of Curcumin-loaded
... anticancer agents and tumour delivery by EpR effect and concleded that Nanotechnology has become an enabling technology for personalised oncology in which cancer detection, diagnosis and therapy are tailored to each individual's tumour molecular profile, and also for predictive oncology in which gen ...
... anticancer agents and tumour delivery by EpR effect and concleded that Nanotechnology has become an enabling technology for personalised oncology in which cancer detection, diagnosis and therapy are tailored to each individual's tumour molecular profile, and also for predictive oncology in which gen ...
NEEDLE FREE INJECTION SYSTEM: A REVIEW Review Article
... Keywords: Needle Free, Injection, Drug delivery, Technology. ...
... Keywords: Needle Free, Injection, Drug delivery, Technology. ...
GASTRO-RETENTIVE DRUG DELIVERY SYSTEM CONTENTS
... The floating sustained release dosage forms present most of the characteristics of hydrophilic matrices and are known as ‘hydrodynamically balanced systems’ (‘HBS’) since they are able to maintain their low apparent density, while the polymer hydrates and builds a gelled barrier at the outer surface ...
... The floating sustained release dosage forms present most of the characteristics of hydrophilic matrices and are known as ‘hydrodynamically balanced systems’ (‘HBS’) since they are able to maintain their low apparent density, while the polymer hydrates and builds a gelled barrier at the outer surface ...
Controlling drug delivery
... specialised sites for absorption. There are many mucosal membranes that can be used for The US Food and Drug Administration drug administration. Of the highest importance (FDA) has compiled an extensive list of are the mucosal membranes of the different dosage forms and different gastrointestinal tr ...
... specialised sites for absorption. There are many mucosal membranes that can be used for The US Food and Drug Administration drug administration. Of the highest importance (FDA) has compiled an extensive list of are the mucosal membranes of the different dosage forms and different gastrointestinal tr ...
Nanoparticles as `smart` pharmaceutical delivery
... Zhao et al. (26), they used gelatin nanoparticles with insulin used for diabetes treatment through pulmonary administration. These findings reflect the better bioavailability, speedy and stable hypoglycemic outcome. Several reports on the applications of gelatin nanoparticle based drug delivery syst ...
... Zhao et al. (26), they used gelatin nanoparticles with insulin used for diabetes treatment through pulmonary administration. These findings reflect the better bioavailability, speedy and stable hypoglycemic outcome. Several reports on the applications of gelatin nanoparticle based drug delivery syst ...
Catalysis for a Sustainable World
... Naonobu Katada received the MS degree in Nagoya University under the supervision of Professor Yuichi Murakami in 1990. After a period of researching for Nippon Shokubai Co. Ltd. in 1990 - 1992, he was appointed a research associate in Tottori University in 1992. He received the PhD degree from Nagoy ...
... Naonobu Katada received the MS degree in Nagoya University under the supervision of Professor Yuichi Murakami in 1990. After a period of researching for Nippon Shokubai Co. Ltd. in 1990 - 1992, he was appointed a research associate in Tottori University in 1992. He received the PhD degree from Nagoy ...
Controlling drug delivery chapter 1 Over view
... sites for absorption. There are many mucosal membranes that can be used for drug administration. Of the highest importance are the mucosal membranes of the gastrointestinal tract, allowing oral drug delivery. The suitability and convenience of this route of delivery make oral dosage forms the most c ...
... sites for absorption. There are many mucosal membranes that can be used for drug administration. Of the highest importance are the mucosal membranes of the gastrointestinal tract, allowing oral drug delivery. The suitability and convenience of this route of delivery make oral dosage forms the most c ...
design and evaluation of fast dissolving oral films of
... Brief Resume of the intended work: 6.1 Need of the study: Among the various routes of administration, the oral route is the most acceptable for the patients. Many pharmaceutical companies have directed their research activity in reformulating existing drugs into new dosage forms. One such relatively ...
... Brief Resume of the intended work: 6.1 Need of the study: Among the various routes of administration, the oral route is the most acceptable for the patients. Many pharmaceutical companies have directed their research activity in reformulating existing drugs into new dosage forms. One such relatively ...
Development of Room Temperature Stable Formulation of
... Gelation temperatures obtained using two different methods (visual inspection and rheological method) did not vary more than ±10. The gelation temperature lowering effect of bioadhesive polymer might have caused in part by the increased viscosity after dissolution of mucosadhesive polymer. The pH va ...
... Gelation temperatures obtained using two different methods (visual inspection and rheological method) did not vary more than ±10. The gelation temperature lowering effect of bioadhesive polymer might have caused in part by the increased viscosity after dissolution of mucosadhesive polymer. The pH va ...
Here - Dipartimento di Scienze Chimiche e Farmaceutiche
... solutions to critical issues in tissue repair and drug delivery applications. Laser-assisted tissue repair or laser welding has been proposed to close chronic accidental and surgical wounds. Typically, laser light is delivered 1) to a wound site to be repaired which has been stained with an exogenou ...
... solutions to critical issues in tissue repair and drug delivery applications. Laser-assisted tissue repair or laser welding has been proposed to close chronic accidental and surgical wounds. Typically, laser light is delivered 1) to a wound site to be repaired which has been stained with an exogenou ...
FORMULATION AND EVALUATION OF OXICONAZOLE NITRATE
... Objective: The aim of the present study was to formulate and evaluate nanoemulsion-based gel of oxiconazole nitrate (OXZ) for the treatment of vaginal infection. Methods: The solubility of Oxiconazole nitrate in various oils, surfactant and co-surfactant, were done to identify the components of the ...
... Objective: The aim of the present study was to formulate and evaluate nanoemulsion-based gel of oxiconazole nitrate (OXZ) for the treatment of vaginal infection. Methods: The solubility of Oxiconazole nitrate in various oils, surfactant and co-surfactant, were done to identify the components of the ...
In Vitro and In Vivo Evaluation of Microparticulate Drug
... biodegradable peptide spacers exhibited a high antitumor effect as compared with DOX itself, and improved the toxic side effects [19-22]. These were achieved by drug targeting based on the EPR effect and adequate drug release patterns at the tumor site. Recently, macromolecular prodrugs of camptothe ...
... biodegradable peptide spacers exhibited a high antitumor effect as compared with DOX itself, and improved the toxic side effects [19-22]. These were achieved by drug targeting based on the EPR effect and adequate drug release patterns at the tumor site. Recently, macromolecular prodrugs of camptothe ...
formulation and in vitro evaluation of microspheres of metoprolol
... polycarbophil were prepared. In this technique cross linking of sodium alginate with calcium chloride was done which retarded the release of drug from the mucoadhesive polymer. The preliminary mucoadhesive strength studies performed for various polymers using rotating cylindrical method showed that ...
... polycarbophil were prepared. In this technique cross linking of sodium alginate with calcium chloride was done which retarded the release of drug from the mucoadhesive polymer. The preliminary mucoadhesive strength studies performed for various polymers using rotating cylindrical method showed that ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.