IN TRIHYDRATE Research Article
... swallowing intact or chewing to deliver a precise dosage of medication to patients. The pills, which include tablets and capsules, are able to retain their shapes under moderate pressure. However, some patients, particularly pediatric, geriatric, bedridden, psychiatry and traveling patients have dif ...
... swallowing intact or chewing to deliver a precise dosage of medication to patients. The pills, which include tablets and capsules, are able to retain their shapes under moderate pressure. However, some patients, particularly pediatric, geriatric, bedridden, psychiatry and traveling patients have dif ...
Phospholipid Complex Technique for Superior Bioavailability of
... phospholipid-complex-technique can enable researchers to deliver the phytoconstituents into systemic circulation by using certain conventional dosage forms like tablets and capsules. This review highlights the unique property of phospholipids in drug delivery, their role as adjuvant in health benefi ...
... phospholipid-complex-technique can enable researchers to deliver the phytoconstituents into systemic circulation by using certain conventional dosage forms like tablets and capsules. This review highlights the unique property of phospholipids in drug delivery, their role as adjuvant in health benefi ...
INVITRO TARTRATE Research Article
... absorbed from oral route but undergoes first pass metabolism, which results in only 38% oral bioavailability. The half life of metoprolol tartrate is approximately 3‐4 hours. Metoprolol tartrate was selected as model drug to avoid first pass hepatic metabolism ...
... absorbed from oral route but undergoes first pass metabolism, which results in only 38% oral bioavailability. The half life of metoprolol tartrate is approximately 3‐4 hours. Metoprolol tartrate was selected as model drug to avoid first pass hepatic metabolism ...
STUDYING THE RELEASE OF DICLOFENAC SODIUM FROM GLYCERIDES Research Article MADY OMAR
... Tablet matrix system containing hydrophobic lipid based materials have been widely used in formulations for controlled drug delivery applications because of their chemical inertness [1], cost effectiveness, regulatory acceptance and above all flexibility to achieve the desired drug release profile [ ...
... Tablet matrix system containing hydrophobic lipid based materials have been widely used in formulations for controlled drug delivery applications because of their chemical inertness [1], cost effectiveness, regulatory acceptance and above all flexibility to achieve the desired drug release profile [ ...
based Micro and Nanoparticles for the Controlled Drug Delivery of
... prepared through the combination of biodegradable and biocompatible materials make a major focus area in the engineering of medical devices [10]. Micro- and nanospheres fabricated from a biodegradable polymer for drug delivery systems have become increasingly important owing to the fact that such sy ...
... prepared through the combination of biodegradable and biocompatible materials make a major focus area in the engineering of medical devices [10]. Micro- and nanospheres fabricated from a biodegradable polymer for drug delivery systems have become increasingly important owing to the fact that such sy ...
Methylergonovine Maleate Injection, USP (0.2 mg/ml)
... grapefruit juice, fluoxetine, fluvoxamine, zileuton, and clotrimazole. These lists are not exhaustive, and the prescriber should consider the effects on CYP 3A4 of other agents being considered for concomitant use with methylergonovine. No pharmacokinetic interactions involving other cytochrome P450 ...
... grapefruit juice, fluoxetine, fluvoxamine, zileuton, and clotrimazole. These lists are not exhaustive, and the prescriber should consider the effects on CYP 3A4 of other agents being considered for concomitant use with methylergonovine. No pharmacokinetic interactions involving other cytochrome P450 ...
Orally disintegrating tablets - Journal of Applied Pharmaceutical
... and are, therefore, less expensive to manufacture (Fasano et al, 2005). A vast variety of pharmaceutical research is directed at developing new dosage forms for oral administration. Most of these efforts have focused on either formulating novel drug delivery systems or increasing the patient complia ...
... and are, therefore, less expensive to manufacture (Fasano et al, 2005). A vast variety of pharmaceutical research is directed at developing new dosage forms for oral administration. Most of these efforts have focused on either formulating novel drug delivery systems or increasing the patient complia ...
PDF - Journal of Nanobiotechnology
... transmembrane permeability [15,16]. Nanocrystals are a fast-release system that has similar effects to those of solid dispersion and cyclodextrin inclusion [6], whereas nanoparticles can alter the permeability of the intestinal membrane by uptake of intact nanoparticles, facilitating adhesion and re ...
... transmembrane permeability [15,16]. Nanocrystals are a fast-release system that has similar effects to those of solid dispersion and cyclodextrin inclusion [6], whereas nanoparticles can alter the permeability of the intestinal membrane by uptake of intact nanoparticles, facilitating adhesion and re ...
EFFECT OF TWO DIFFERENT DILUENTS ON RELEASE PROFILE OF ACECLOFENAC FROM SUSTAINED RELEASE MATRIX TABLETS USING GUM DAMAR AS RELEASE RETARDANT
... In the present work the effect of two different diluents namely dicalcium phosphate (DCP) and maize starch (MS) on the release of aceclofenac from sustained release matrix tablets has been studied. Gum damar (GD), a hydrophobic polymer with significant binding property was used as a release retard ...
... In the present work the effect of two different diluents namely dicalcium phosphate (DCP) and maize starch (MS) on the release of aceclofenac from sustained release matrix tablets has been studied. Gum damar (GD), a hydrophobic polymer with significant binding property was used as a release retard ...
HIGH-MOLECULAR WEIGHT OF BIOPOLYMER
... which the system of ascorbate and metal cation as copper (II) ions enduces hydrogen peroxide (H2O2) to turn into OH- radicals by a Fenton-like reaction and this system is called Weissberger’s oxidative system. They observed a decrease of the dynamic viscosity value of the HA solution, and this indic ...
... which the system of ascorbate and metal cation as copper (II) ions enduces hydrogen peroxide (H2O2) to turn into OH- radicals by a Fenton-like reaction and this system is called Weissberger’s oxidative system. They observed a decrease of the dynamic viscosity value of the HA solution, and this indic ...
APPLICATION OF NOVEL CONCEPT OF MIXED SOLVENCY IN THE DESIGN... DEVELOPMENT OF FLOATING MICROSPHERS OF FUROSEMIDE
... Oral drug delivery is the most desirable method of administering therapeutic agents mainly because of patient acceptance, convenience in administration, and cost-effective manufacturing process. For many drug substances, conventional immediate-release formulations provide clinically effective therap ...
... Oral drug delivery is the most desirable method of administering therapeutic agents mainly because of patient acceptance, convenience in administration, and cost-effective manufacturing process. For many drug substances, conventional immediate-release formulations provide clinically effective therap ...
develpoment and evaluation of sustained release formulations of
... solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such as HPMC, Eudragit RS100, and Ethyl cellulose as releases retardants. All the precompressional parameters were found to be within the standard l ...
... solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such as HPMC, Eudragit RS100, and Ethyl cellulose as releases retardants. All the precompressional parameters were found to be within the standard l ...
IN VITRO NATURAL GUM AND IT’S SOLID CHARACTERIZATION
... imidazole with a biological half life of 2-2.5h [2,3]. Its adult dose is 25mg, 50 mg and 100 mg once daily based on the requirement as prophylactic, for treatment and in severe conditions. Oral timed–release tablets (TRT) are dosage forms used for chronotherapeutic drug delivery [4]. These systems c ...
... imidazole with a biological half life of 2-2.5h [2,3]. Its adult dose is 25mg, 50 mg and 100 mg once daily based on the requirement as prophylactic, for treatment and in severe conditions. Oral timed–release tablets (TRT) are dosage forms used for chronotherapeutic drug delivery [4]. These systems c ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
... of drug administration. The advances in the formulation technology of modified release dosage form with extended release oral dosage form has been widely accepted approach as compared to conventional immediate release formulations of the same drug, over which it provides a prolong release of the dru ...
... of drug administration. The advances in the formulation technology of modified release dosage form with extended release oral dosage form has been widely accepted approach as compared to conventional immediate release formulations of the same drug, over which it provides a prolong release of the dru ...
Poloxamer: A Novel Functional Molecule For Drug Delivery And
... Poloxamer: A Novel Functional Molecule For Drug Delivery And Gene Therapy D. Ramya Devi,* P. Sandhya, B.N. Vedha Hari Department of Pharmaceutical Technology, School of Chemical and Biotechnology, SASTRA University, Thanjavur – 613 401 Abstract: Aim: Poloxamer a block copolymer is well known for its ...
... Poloxamer: A Novel Functional Molecule For Drug Delivery And Gene Therapy D. Ramya Devi,* P. Sandhya, B.N. Vedha Hari Department of Pharmaceutical Technology, School of Chemical and Biotechnology, SASTRA University, Thanjavur – 613 401 Abstract: Aim: Poloxamer a block copolymer is well known for its ...
In vitro Nanoparticles Sareh Arjmand, Elham Bidram, Abbas
... (day 1 to 3) with 60% of the AAT released. The second phase was an intermediate one (day 4 to 9) with a low and continuous release including approximately a 36% of release and finally a third phase (till day 36) was detected with a moderate burst (Fig. 2). ...
... (day 1 to 3) with 60% of the AAT released. The second phase was an intermediate one (day 4 to 9) with a low and continuous release including approximately a 36% of release and finally a third phase (till day 36) was detected with a moderate burst (Fig. 2). ...
bioreactors chemostats
... The 170A/B series is a two semester sequence intended to introduce chemical engineers to the basic concepts of biochemical engineering. The course focuses on the use of chemical engineering skills and principles in the analysis and design of biologically‐based processes. The emphases of 170A will ...
... The 170A/B series is a two semester sequence intended to introduce chemical engineers to the basic concepts of biochemical engineering. The course focuses on the use of chemical engineering skills and principles in the analysis and design of biologically‐based processes. The emphases of 170A will ...
Development and in-vitro characterization of sustained release
... on X- axis against percent cumulative drug release on Y-axis.The results were tabulated in Table.8 and Figure.7. Drug release kinetics of the selected formulation [12]: The release kinetics and curve fitting was studied using an MS- Excel based software program. STABILITY STUDIES [13, 14]: Stability ...
... on X- axis against percent cumulative drug release on Y-axis.The results were tabulated in Table.8 and Figure.7. Drug release kinetics of the selected formulation [12]: The release kinetics and curve fitting was studied using an MS- Excel based software program. STABILITY STUDIES [13, 14]: Stability ...
Pelagia Research Library Hydroxypropyl methylcellulose
... or loss of function. These all will instigate for searching new useful therapy. Hydrogels based materials are investigated to develop new improved ocular delivery. Hydrogel systems are ...
... or loss of function. These all will instigate for searching new useful therapy. Hydrogels based materials are investigated to develop new improved ocular delivery. Hydrogel systems are ...
Wet-lab drug discovery process
... between the ligand and the side chains of the amino acids in the active site. (electrostatic interactions, hydrogen bonds, hydrophobic contacts...) ...
... between the ligand and the side chains of the amino acids in the active site. (electrostatic interactions, hydrogen bonds, hydrophobic contacts...) ...
Reassessing Bioavailability of Silymarin
... of silymarin have revealed poor absorption, rapid metabolism, and ultimately poor oral bioavailability. For optimum silymarin bioavailability, issues of solubility, permeability, metabolism, and excretion must be addressed. An array of methods have been described in recent years that can improve its ...
... of silymarin have revealed poor absorption, rapid metabolism, and ultimately poor oral bioavailability. For optimum silymarin bioavailability, issues of solubility, permeability, metabolism, and excretion must be addressed. An array of methods have been described in recent years that can improve its ...
Formulation and Evaluation of Itopride Hydrochloride Floating
... systems. It is evident from the recent scientific and patient literature that an increased interest in novel dosage forms that are retained in stomach for a prolonged and predictable period of time exists today in academic and industrial research groups. One of the most feasible approaches for achie ...
... systems. It is evident from the recent scientific and patient literature that an increased interest in novel dosage forms that are retained in stomach for a prolonged and predictable period of time exists today in academic and industrial research groups. One of the most feasible approaches for achie ...
4 2. LITERATURE REVIEW: Ariyana, et al (2014), developed
... Raghavendra N, et al (2012), reported formulation, in vitro characterization and clinical evaluation of ofloxacin medicated dental gels for periodontal infections. The ofloxacin dental gels were prepared with different hydrophilic polymers methyl cellulose, hydroxy propyl methyl cellulose, hydroxy ...
... Raghavendra N, et al (2012), reported formulation, in vitro characterization and clinical evaluation of ofloxacin medicated dental gels for periodontal infections. The ofloxacin dental gels were prepared with different hydrophilic polymers methyl cellulose, hydroxy propyl methyl cellulose, hydroxy ...
Document
... One of our greatest prevention challenges in the next decade will not be that we lack options, but prioritizing to advance the best prevention options The prevention field is positioned to not only optimally deliver prevention strategies, but to also provide a range of delivery choices to men and wo ...
... One of our greatest prevention challenges in the next decade will not be that we lack options, but prioritizing to advance the best prevention options The prevention field is positioned to not only optimally deliver prevention strategies, but to also provide a range of delivery choices to men and wo ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.