Synthesis and Characterization of Amorphous and Hybrid Materials
... processes as well. Those problems can be overcome by using local drug delivery methods to confine pharmaceuticals such as antibiotics, anti-inflammatory, anti-carcinogens, etc. (Arcos et. al., 2001; Ragel & Vallet-Regì, 2000; Vallet-Regì et al., 2000). The possibility of introducing certain drugs in ...
... processes as well. Those problems can be overcome by using local drug delivery methods to confine pharmaceuticals such as antibiotics, anti-inflammatory, anti-carcinogens, etc. (Arcos et. al., 2001; Ragel & Vallet-Regì, 2000; Vallet-Regì et al., 2000). The possibility of introducing certain drugs in ...
FORMULATION AND EVALUATION OF ORODISPERSIBLE FILM OF SILDENAFILCITRATE Research Article
... forms have presented viable dosage alternatives from oralroute for pediatrics, geriatric, bedridden, nauseous or noncompliant patients ...
... forms have presented viable dosage alternatives from oralroute for pediatrics, geriatric, bedridden, nauseous or noncompliant patients ...
tablet (ODT) - Rajiv Gandhi University of Health Sciences
... uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult. This paper summarizes the formulation methods and drug formulation ...
... uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult. This paper summarizes the formulation methods and drug formulation ...
Syllabi of Master of Pharmaceutical Sciences in SEMESTER-I (M
... model like Hixson-Crowell, Higuchi’s Model. Drug release modeling through polymer matrix & laminates. Concept of membrane controlled delivery & its importance in dosage form design. MICRO ENCAPSULATION: Theory, methods, applications, kinetics of release of drugs from microcapsules, formulations and ...
... model like Hixson-Crowell, Higuchi’s Model. Drug release modeling through polymer matrix & laminates. Concept of membrane controlled delivery & its importance in dosage form design. MICRO ENCAPSULATION: Theory, methods, applications, kinetics of release of drugs from microcapsules, formulations and ...
formulation and invitro evaluation of sustained release matrix
... Since there is increasing cost and complication involved in the development and marketing of new drug entities, this has forced most of the pharmaceutical industries to focus their attention on the development of sustained/controlled/ prolonged system. This sustained release dosage forms are becomin ...
... Since there is increasing cost and complication involved in the development and marketing of new drug entities, this has forced most of the pharmaceutical industries to focus their attention on the development of sustained/controlled/ prolonged system. This sustained release dosage forms are becomin ...
... The dissolution rate of selected prepared formulations F2 and F8 were compared with that of marketed conventional tablet. The F8 formulation shown prolonged release (86%) up to 12 hrs, but the marketed tablet released 97% of drug within 2.5 hrs. Further, to confirm the mechanism of drug release, F2 ...
Gastroretentive Drug Delivery Systems As A Potential Tool For
... optimum formula loaded with barium sulfate, in six healthy human volunteers was 5.50 ± 0.77 h. Bomma et al.24 developed floating matrix tablets of norfloxacin by the wet granulation technique, using three different polumers, namely; hydroxypropyl methylcellulose (HPMC K4M, HPMC K100M) and xanthan gu ...
... optimum formula loaded with barium sulfate, in six healthy human volunteers was 5.50 ± 0.77 h. Bomma et al.24 developed floating matrix tablets of norfloxacin by the wet granulation technique, using three different polumers, namely; hydroxypropyl methylcellulose (HPMC K4M, HPMC K100M) and xanthan gu ...
Contained Chemistry - SafeBridge Consultants, Inc.
... "Because the quantities are smaller, a lot of companies think this is easier to do," Van Tilburg says about high-potency manufacturing. "But it's a completely different ballgame—you need different people, different expertise, different equipment, and different motivation." For these reasons, compani ...
... "Because the quantities are smaller, a lot of companies think this is easier to do," Van Tilburg says about high-potency manufacturing. "But it's a completely different ballgame—you need different people, different expertise, different equipment, and different motivation." For these reasons, compani ...
FORMULATION AND EVALUATION OF PULSATILE TABLET IN CAPSULE DEVICE Research Article
... System for Colonic Drug Delivery, Drug Development and Industrial Pharmacy, 2003 (29), 661–667. Zou H, Jiang X., Design and gamma-scintigraphic evaluation of a floating and pulsatile drug delivery system based on an impermeable cylinder. Chem. Pharm. Bull. 2007; 55:580–585. Pradeep K. S., Pratibha D ...
... System for Colonic Drug Delivery, Drug Development and Industrial Pharmacy, 2003 (29), 661–667. Zou H, Jiang X., Design and gamma-scintigraphic evaluation of a floating and pulsatile drug delivery system based on an impermeable cylinder. Chem. Pharm. Bull. 2007; 55:580–585. Pradeep K. S., Pratibha D ...
here - CPhI North America
... to attractive interactions (Derjaguin-Landau-VerweyOverbeek theory). The primary objective of a robust formulation development is to reduce the rate of change of both physical and chemical degradation of a protein by optimizing conformational and colloidal stabilities. Uncluttered experimental strat ...
... to attractive interactions (Derjaguin-Landau-VerweyOverbeek theory). The primary objective of a robust formulation development is to reduce the rate of change of both physical and chemical degradation of a protein by optimizing conformational and colloidal stabilities. Uncluttered experimental strat ...
INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND BIO
... 14. Sanju D, Bikash M, Sunny C. Formulation and evaluation of diltiazem Hydrochloride Gels for the Treatment of Anal Fissures. Scientia Pharmaceutica 2009;77: 465–82. 15. Lalit K, Ruchi V. In vitro evaluation of topical gel prepared using natural polymer. International journal of drug delivery 2010; ...
... 14. Sanju D, Bikash M, Sunny C. Formulation and evaluation of diltiazem Hydrochloride Gels for the Treatment of Anal Fissures. Scientia Pharmaceutica 2009;77: 465–82. 15. Lalit K, Ruchi V. In vitro evaluation of topical gel prepared using natural polymer. International journal of drug delivery 2010; ...
CONTROLLED RELEASE OF A WATER SOLUBLE DRUG, METOPROLOL SUCCINATE, BY... LACTALBUMIN MICROPARTICLES
... efficacy. To this effect, extensive investigations are being carried out to unravel new and potential drug carriers. The design of such stable drug carriers, logistically, is followed by engineering the carriers to achieve targeted delivery. Concentration of the drugs delivered / released also has g ...
... efficacy. To this effect, extensive investigations are being carried out to unravel new and potential drug carriers. The design of such stable drug carriers, logistically, is followed by engineering the carriers to achieve targeted delivery. Concentration of the drugs delivered / released also has g ...
Self-Emulsifying Drug Delivery Systems: Strategy for Improving Oral De-
... A convenient and reliable model for evaluating cytotoxicity is the use of a human epithelial Caco-2 cell line. Palamakula et al. have developed a suitable method for evaluating the cytotoxicity of oils used in SEDDS using Coenzyme Q10 (Co Q10) as a model compound [16]. Three methods of sample prepar ...
... A convenient and reliable model for evaluating cytotoxicity is the use of a human epithelial Caco-2 cell line. Palamakula et al. have developed a suitable method for evaluating the cytotoxicity of oils used in SEDDS using Coenzyme Q10 (Co Q10) as a model compound [16]. Three methods of sample prepar ...
FORMULATION AND EVALUATION OF DICLOFANAC POTASSIUM ETHOSOMES Research Article VIJAYAKUMAR M.R., ABDUL HASAN SATHALI A , ARUN K.
... The structure of stratum corneum is often compared with a brick wall, with the corneocytes as the bricks surrounded by the mortar of the intercellular lipid lamellae. Many techniques have been aimed to disrupt and weaken the highly organized intercellular lipids in an attempt ...
... The structure of stratum corneum is often compared with a brick wall, with the corneocytes as the bricks surrounded by the mortar of the intercellular lipid lamellae. Many techniques have been aimed to disrupt and weaken the highly organized intercellular lipids in an attempt ...
Chapter-7 Summary
... followed by literature review in chapter 2. The Drug and polymer profile was discussed in chapter 3. The objectives of the study were briefed in chapter 4 and elaborate methodology in chapter 5. Results and discussion was made in chapter 6. Summary was presented in chapter 7. Conclusion was finally ...
... followed by literature review in chapter 2. The Drug and polymer profile was discussed in chapter 3. The objectives of the study were briefed in chapter 4 and elaborate methodology in chapter 5. Results and discussion was made in chapter 6. Summary was presented in chapter 7. Conclusion was finally ...
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES AND
... which results to the formation of gel. This gel formation allows to heat with addition of PBS on water bath at 60°C for 10 minute to yield niosomes. [21-22] 5) Trans membrane pH gradient drug uptake process (Remote Loading): - this method principles, that the interior of niosome has the low pH value ...
... which results to the formation of gel. This gel formation allows to heat with addition of PBS on water bath at 60°C for 10 minute to yield niosomes. [21-22] 5) Trans membrane pH gradient drug uptake process (Remote Loading): - this method principles, that the interior of niosome has the low pH value ...
Development, characterization and in vitro biological
... Continual testing was performed using a controlled shear rate procedure in the range from 0.01 to 100 s-1 and back, each stage lasting 120 s, with an interval of 10 s between the curves. The consistency index and flow index were determined from the Power law described in equation 1 for a quantitativ ...
... Continual testing was performed using a controlled shear rate procedure in the range from 0.01 to 100 s-1 and back, each stage lasting 120 s, with an interval of 10 s between the curves. The consistency index and flow index were determined from the Power law described in equation 1 for a quantitativ ...
et al. TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS): AN OVERVIEW
... R. K. Tyagi, A. Chandra, D. Singh, Md. A. Rahman* Department of Pharmacy, Institute of Bio-Medical Education and Research, Mangalayatan University , Aligarh, Uttar Pradesh, India ...
... R. K. Tyagi, A. Chandra, D. Singh, Md. A. Rahman* Department of Pharmacy, Institute of Bio-Medical Education and Research, Mangalayatan University , Aligarh, Uttar Pradesh, India ...
BAOJ Pharmaceutical Sciences
... Department of Pharmaceutics, Sahasra Institute of Pharmaceutical Sciences, Warangal, India Talla Padmavathi College of Pharmacy, Warangal, India ...
... Department of Pharmaceutics, Sahasra Institute of Pharmaceutical Sciences, Warangal, India Talla Padmavathi College of Pharmacy, Warangal, India ...
AN EVOLUTIONARY APPROACHS IN DEVELOPMENT OF NEEDLE FREE INJECTION TECHNOLOGIES Review Article
... transport enhancement mechanism. The pitfalls of needle-based injections are psychological resistances to self-injection or needlephobia, awareness of serious problems has caused physicians and their patients to either delay therapy initiation or seek out lessinvasive alternatives and even at some c ...
... transport enhancement mechanism. The pitfalls of needle-based injections are psychological resistances to self-injection or needlephobia, awareness of serious problems has caused physicians and their patients to either delay therapy initiation or seek out lessinvasive alternatives and even at some c ...
PDF - International Journal of Pharma and Bio Sciences
... prepared with modified gum karaya in 5-20% concentration. Drug release from the formulated amoxicillin trihydrate loaded buccal tablets followed Zero order kinetics resulting in regulated and controlled release for a given time from all the batches. Swelling index increased with increase in concentr ...
... prepared with modified gum karaya in 5-20% concentration. Drug release from the formulated amoxicillin trihydrate loaded buccal tablets followed Zero order kinetics resulting in regulated and controlled release for a given time from all the batches. Swelling index increased with increase in concentr ...
KINETIC STUDY OF THE IN VITRO RELEASE AND STABILITY OF... FLOATING BEADS Research Article
... 2%. Light paraffin oil (5-20% w/w) was added to the prepared polymer solution. Theophylline (200 mg) was then added. The mixture was homogenized for 15 minutes and was then extruded through 23G needle at a height of 20 cm in to 5% calcium chloride solution with gentle agitation at room temperature. ...
... 2%. Light paraffin oil (5-20% w/w) was added to the prepared polymer solution. Theophylline (200 mg) was then added. The mixture was homogenized for 15 minutes and was then extruded through 23G needle at a height of 20 cm in to 5% calcium chloride solution with gentle agitation at room temperature. ...
FORMULATION AND EVALUATION OF PH TRIGGERED IN SITU OPHTHALMIC GEL... MOXIFLOXACIN HYDROCHLORIDE Research Article
... common method of drug treatment for ocular diseases and diagnosis 1. Eye drops that are conventional ophthalmic delivery systems often result in poor bioavailability and therapeutic response since the high tear fluid turnover and dynamics cause rapid precorneal elimination of the drug 2. A high freq ...
... common method of drug treatment for ocular diseases and diagnosis 1. Eye drops that are conventional ophthalmic delivery systems often result in poor bioavailability and therapeutic response since the high tear fluid turnover and dynamics cause rapid precorneal elimination of the drug 2. A high freq ...
PAMAM Dendrimer Conjugates for Intracellular Delivery of N
... the nanodevices indicates that we successfully engineered Glutathione sensitive PAMAM dendrimer conjugates with high payload that release NAC specifically inside the cells and have higher in vitro efficacy compared to free NAC. PAMAM dendrimers are highly hyper-branched synthetic polymers with well ...
... the nanodevices indicates that we successfully engineered Glutathione sensitive PAMAM dendrimer conjugates with high payload that release NAC specifically inside the cells and have higher in vitro efficacy compared to free NAC. PAMAM dendrimers are highly hyper-branched synthetic polymers with well ...
THERMOSENSITIVE HYDROGEL FOR CONTROLLED DRUG DELIVERY OF ANTICANCER AGENTS Research Article
... interest in drug delivery and tissue engineering. These devices can overcome many of the problems associated with polymers or microspheres in that they are both injectable and produce solid biodegradable implants with a range of mechanical characteristics in terms of rigidity and load bearing making ...
... interest in drug delivery and tissue engineering. These devices can overcome many of the problems associated with polymers or microspheres in that they are both injectable and produce solid biodegradable implants with a range of mechanical characteristics in terms of rigidity and load bearing making ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.