INSITU GELLING OPHTHALMIC DRUG DELIVERY SYSTEM: AN OVERVIEW Review Article
... physicochemical evaluations. Ocular inserts prepared were smooth and passed all the evaluation tests performed. Formulation OF2 shows a maximum cumulative percentage drug release of 91.27 % at the end of 24 hours. Ocuserts formulated also passed the test for sterility. T ...
... physicochemical evaluations. Ocular inserts prepared were smooth and passed all the evaluation tests performed. Formulation OF2 shows a maximum cumulative percentage drug release of 91.27 % at the end of 24 hours. Ocuserts formulated also passed the test for sterility. T ...
Polysaccharides Based Colon Specific Drug delivery: A
... divided into various regions like stomach, small intestine and large intestine. The colon serves four major functions: viz; creation of suitable environment for the growth of colonic microorganisms, storage reservoir of faecal contents, expulsion of the contents of the colon at an appropriate time, ...
... divided into various regions like stomach, small intestine and large intestine. The colon serves four major functions: viz; creation of suitable environment for the growth of colonic microorganisms, storage reservoir of faecal contents, expulsion of the contents of the colon at an appropriate time, ...
Formulation and Evaluation of Terbutaline Sulphate Loaded
... Department of Pharmaceutics, P. Rami Reddy Memorial College of Pharmacy, Utukur, Kadapa, Andhra Pradesh, India. *Corresponding author’s E-mail: [email protected] Received: 15-10-2016; Revised: 25-12-2017; Accepted: 08-01-2017. ABSTRACT The main aim of present research work is to design Terbutalin ...
... Department of Pharmaceutics, P. Rami Reddy Memorial College of Pharmacy, Utukur, Kadapa, Andhra Pradesh, India. *Corresponding author’s E-mail: [email protected] Received: 15-10-2016; Revised: 25-12-2017; Accepted: 08-01-2017. ABSTRACT The main aim of present research work is to design Terbutalin ...
Hydrogels for protein delivery in tissue engineering ⁎ Roberta Censi
... proteolytic degradation upon oral administration. Hydrogels are frequently used to release growth factors in a controlled and effective manner and to direct the protein specifically to the wound site [10,11]. Spatiotemporal control over the delivery of these key signaling molecules not only enhances ...
... proteolytic degradation upon oral administration. Hydrogels are frequently used to release growth factors in a controlled and effective manner and to direct the protein specifically to the wound site [10,11]. Spatiotemporal control over the delivery of these key signaling molecules not only enhances ...
formulation and delivery strategies
... protein solutions are very viscous, making them hard to administer. The creation of formulations with lower viscosities will thus be extremely useful. Approaches to achieve this includes the addition of hydrophobic salts or inorganic salts189,190, or the addition of lysine or arginine191. The high v ...
... protein solutions are very viscous, making them hard to administer. The creation of formulations with lower viscosities will thus be extremely useful. Approaches to achieve this includes the addition of hydrophobic salts or inorganic salts189,190, or the addition of lysine or arginine191. The high v ...
FORMULATION AND EVALUATION OF ALCOHOL RESISTANT DOSAGE FORMS OF DICLOFENAC SODIUM
... alcohol. Drug release from the pellets was by non fickian diffusion mechanism and was comparable with that of marketed preparations. The pellets also had shown resistance to alcohol dose dumping. Keywords: Diclofenac, Pellets, Eudragits, Cellulose acetate butyrate, Alcohol resistance. ...
... alcohol. Drug release from the pellets was by non fickian diffusion mechanism and was comparable with that of marketed preparations. The pellets also had shown resistance to alcohol dose dumping. Keywords: Diclofenac, Pellets, Eudragits, Cellulose acetate butyrate, Alcohol resistance. ...
Effect of Excipients on Oxcarbazepine Release from Modified
... release (MR) matrix tablets of Oxcarbazepine (OXC) an anti-epileptic drug, based on cellulose ether polymers like Hydroxy Propyl Methyl Cellulose (HPMC K4M and LVCR 100) and Hydroxy Propyl Cellulose (HPC JF) as drug release retardants to overcome poor patient compliance and exposure to high doses as ...
... release (MR) matrix tablets of Oxcarbazepine (OXC) an anti-epileptic drug, based on cellulose ether polymers like Hydroxy Propyl Methyl Cellulose (HPMC K4M and LVCR 100) and Hydroxy Propyl Cellulose (HPC JF) as drug release retardants to overcome poor patient compliance and exposure to high doses as ...
FORMULATION AND EVALUATION OF CARBAMAZEPINE EXTENDED RELEASE TABLET BY Research Article
... The objective of the present study was to design and develop the carbamazepine extended release tablet fabricated by controlled erosion technology. The core tablets were prepared by wet granulation technique using hydroxypropyl methyl cellulose E5 as hydrophilic matrix. The prepared core matrix tabl ...
... The objective of the present study was to design and develop the carbamazepine extended release tablet fabricated by controlled erosion technology. The core tablets were prepared by wet granulation technique using hydroxypropyl methyl cellulose E5 as hydrophilic matrix. The prepared core matrix tabl ...
Sustained release drug delivery system
... Introduction of matrix tablet as sustained release (SR) has given a new breakthrough for novel drug delivery system (NDDS) in the field of Pharmaceutical technology. It excludes complex production procedures such as coating and pelletization during manufacturing and drug release rate from the dosage ...
... Introduction of matrix tablet as sustained release (SR) has given a new breakthrough for novel drug delivery system (NDDS) in the field of Pharmaceutical technology. It excludes complex production procedures such as coating and pelletization during manufacturing and drug release rate from the dosage ...
... dosage form is also convenient for patients who experience dysphasia that is difficulty in swallowing. In this case, rapidly disintegrating dosage forms are superior over conventional dosage forms in terms of patient compliance. Controlled release ODT can offer advantages of both, ODT technology and ...
1 Rede Temática em Engenharia de Materiais UFOP
... mechanical engineers. In the absence of a metallurgy department, the mechanical engineering department commonly included a metallurgist as a faculty member. Relatively few schools had ceramic engineering departments. Also, academic contacts between the engineering units and those chemists focusing o ...
... mechanical engineers. In the absence of a metallurgy department, the mechanical engineering department commonly included a metallurgist as a faculty member. Relatively few schools had ceramic engineering departments. Also, academic contacts between the engineering units and those chemists focusing o ...
pH TRIGGERED DRUG DELIVERY OF ORNIDAZOLE FROM EUDRAGIT COATED CHITOSAN MICROSPHERE:
... The drug entrapment efficiency of chitosan microspheres was found to be 65.7 to 86.5%. That showed good entrapment efficiency of drug. In-vitro drug release of Eudragit S-100 Chitosan microspheres The results of in-vitro dissolution study of Eudragit S-100 coated microspheres showed that release o ...
... The drug entrapment efficiency of chitosan microspheres was found to be 65.7 to 86.5%. That showed good entrapment efficiency of drug. In-vitro drug release of Eudragit S-100 Chitosan microspheres The results of in-vitro dissolution study of Eudragit S-100 coated microspheres showed that release o ...
Hospital brochure - LMA™ Better by design
... of healthcare professionals and is an effective alternative drug delivery method, for use with drugs approved for nasal delivery. ...
... of healthcare professionals and is an effective alternative drug delivery method, for use with drugs approved for nasal delivery. ...
Phytosomes - Journal of Chemical and Pharmaceutical Research
... extracts of Ginkgo biloba, Grape seed, Green tea, Ginseng, etc. has been profitably used. Phytosomes have been refined for therapeutic uses like cardiovascular, anti-inflammatory, immunomodulator, anticancer, antidiabetic etc. or for preventive and health reasons. In the ever-expanding pharmaceutica ...
... extracts of Ginkgo biloba, Grape seed, Green tea, Ginseng, etc. has been profitably used. Phytosomes have been refined for therapeutic uses like cardiovascular, anti-inflammatory, immunomodulator, anticancer, antidiabetic etc. or for preventive and health reasons. In the ever-expanding pharmaceutica ...
Slide 1
... covered with fine drug particles and a bioadhesive component. With this approach, it is possible to obtain rapid dissolution in combination with bioadhesive retention of the drug in the oral ...
... covered with fine drug particles and a bioadhesive component. With this approach, it is possible to obtain rapid dissolution in combination with bioadhesive retention of the drug in the oral ...
15. Recent Trends in Sustained Release Drug Delivery System
... It is defined as one for which the drug release characteristics of time course and/or location are chosen to accomplish therapeutic or convenience objectives not offered by conventional dosage forms such as solutions, ointments, tablets and capsules.1 Delayed Release These systems are those that use ...
... It is defined as one for which the drug release characteristics of time course and/or location are chosen to accomplish therapeutic or convenience objectives not offered by conventional dosage forms such as solutions, ointments, tablets and capsules.1 Delayed Release These systems are those that use ...
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF
... prostaglandin E2 (PGE2) production. Effects on cell adhesion molecular from neurophils have also been noted. In vitro data indicate inhibition of cyclooxygenase (Cox)-1 and 2 by Aceclofenac in whole blood assays, with selectivity for Cox-2 being evident. The half-life of Aceclofenac is around 4 hrs, ...
... prostaglandin E2 (PGE2) production. Effects on cell adhesion molecular from neurophils have also been noted. In vitro data indicate inhibition of cyclooxygenase (Cox)-1 and 2 by Aceclofenac in whole blood assays, with selectivity for Cox-2 being evident. The half-life of Aceclofenac is around 4 hrs, ...
innovative self-injection solutions
... provide simple, cost-effective solutions for self-injection. Experienced Over 100 years of combined experience in providing drug delivery technologies for the global pharmaceutical industry. Cost-effective Autoinjector devices, syringe filling, device assembly and packaging providing economic soluti ...
... provide simple, cost-effective solutions for self-injection. Experienced Over 100 years of combined experience in providing drug delivery technologies for the global pharmaceutical industry. Cost-effective Autoinjector devices, syringe filling, device assembly and packaging providing economic soluti ...
FORMULATION AND EVALUATION OF FLOATING MATRIX TABLET OF ATENOLOL FOR
... The purpose of this research was to develop gastro-retentive delivery system of atenolol which, after oral administration should have the ability to prolong gastric residence time with desired in vitro release profile. Atenolol was chosen as a model drug because it is poorly absorbed from the lower ...
... The purpose of this research was to develop gastro-retentive delivery system of atenolol which, after oral administration should have the ability to prolong gastric residence time with desired in vitro release profile. Atenolol was chosen as a model drug because it is poorly absorbed from the lower ...
DEVELOPMENT OF FAST DISSOLVING ORAL FILMS AND TABLETS OF CINNARIZINE:... OF SUPERDISINTEGRANTS Research Article
... disintegration/dissolution times. However, to overcome fear of taking solid tablets and the risk of choking for certain patient population, a new drug delivery system was introduced as fast dissolving oral films (FDOFs). FDOFs are the most advanced form of oral solid form due to more flexibility and ...
... disintegration/dissolution times. However, to overcome fear of taking solid tablets and the risk of choking for certain patient population, a new drug delivery system was introduced as fast dissolving oral films (FDOFs). FDOFs are the most advanced form of oral solid form due to more flexibility and ...
IN VITRO Research Article SAKTHIVEL M*
... cholesterol and surfactant were dissolved in chloroform and methanol mixture (1:1 v/v) taken in a round bottom flask. The flask was rotated in rotary flash evaporator at 100 rpm for 20 minutes in a thermostatically controlled water bath at 60°C± 2°C.The flask was rotated at 1.5 cm above the water ba ...
... cholesterol and surfactant were dissolved in chloroform and methanol mixture (1:1 v/v) taken in a round bottom flask. The flask was rotated in rotary flash evaporator at 100 rpm for 20 minutes in a thermostatically controlled water bath at 60°C± 2°C.The flask was rotated at 1.5 cm above the water ba ...
EXTENDED RELEASE ROPINIROLE TABLET FORMULATION PREPARED BY MELT GRANULATION TECHNIQUE Research Article
... with polyox WSR 301 than carbopol 71G with various proportions of cetyl alcohol. Amongst these formulations, the release rate was observed in the following order: Drug: CA (1:1) > Drug: CA (1:2) > Drug: CA (1:3) > Drug: CA (1:5), indicating decrease in release rate with increase in the lipophilicity ...
... with polyox WSR 301 than carbopol 71G with various proportions of cetyl alcohol. Amongst these formulations, the release rate was observed in the following order: Drug: CA (1:1) > Drug: CA (1:2) > Drug: CA (1:3) > Drug: CA (1:5), indicating decrease in release rate with increase in the lipophilicity ...
FORMULATION AND EVALUATION OF BIOPOLYMER BASED TRANSDERMAL DRUG DELIVERY Research Article RAJESH N
... In recent years transdermal route now ranks with oral treatment as the most successful innovative research area in drug delivery, with around 40% of the drug delivery candidate products under clinical evaluation related to transdermal or dermal system. The transdermal drug deliv ...
... In recent years transdermal route now ranks with oral treatment as the most successful innovative research area in drug delivery, with around 40% of the drug delivery candidate products under clinical evaluation related to transdermal or dermal system. The transdermal drug deliv ...
DESIGN DEVELOPMENT AND EVALUATION OF MATRIX TABLETS OF AMBROXOL Original Article
... frequent daily dosing (2 to 3 times) and therapeutic use in chronic respiratory diseases necessitates its formulation into sustained release dosage form [1]. The development of oral controlled release dosage forms has attracted much attention in the recent years and hydrophilic matrix tablets are am ...
... frequent daily dosing (2 to 3 times) and therapeutic use in chronic respiratory diseases necessitates its formulation into sustained release dosage form [1]. The development of oral controlled release dosage forms has attracted much attention in the recent years and hydrophilic matrix tablets are am ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.