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Water Soluble Polymers for Pharmaceutical Applications
Water Soluble Polymers for Pharmaceutical Applications

... PEG-drug conjugates are being studied for a variety of molecules and drugs including insulin, daunorubicin camptothecin, peptides and lipids. The main advantages of PEG-drug conjugates Are reduced protein immunogenicity, increased residence time in the body, reduced enzymatic degradation. All these ...
Hydroxyapatite/Nanodiamond Hydrogels as Potential Materials for
Hydroxyapatite/Nanodiamond Hydrogels as Potential Materials for

... albumin (0.8 mg/ml), phosphate buffer, pH 7.4 (10 mM), water to reach 2.5 ml total volume, antioxidant (such as B12, N-acetyl cysteine and corresponding chitosan/hydroxyapaitite hydrogels) tested to reach required concentration as shown in results, EDTA (0-/4.8 mM), Fe(NH4)2(SO4)2 (0-/4 mM), ascorba ...
DESIGN AND EVALUATION OF CONTROLLED RELEASE TABLETS OF LIPID LOWERING
DESIGN AND EVALUATION OF CONTROLLED RELEASE TABLETS OF LIPID LOWERING

... A method of avoiding or reducing the side effects associated with immediate release of drugs like NA is the use of CR formulations. CR formulations are designed to slowly release the active ingredient from the tablet, which allows a reduction in dosing frequency as compared to the typical dosing fre ...
Leading in
Leading in

... The 3M™ Retention Valve has been developed to provide good ‘prime’ valves and cans in-house, benefiting partner retention over seven days, resulting in low loss of dose and excellent dose companies by ensuring component compatibility uniformity for the patient. The all-metal valve system has clean E ...
Kidney-Specific Drug Delivery: Review of Opportunities
Kidney-Specific Drug Delivery: Review of Opportunities

... following to their approval for use in humans by the American Food and Drug Administration (FDA) [31]. Parenteral application of microspheres and nanoparticles for the cell selective delivery of drugs is not the only administration route since they have been studied more recently for their applicati ...
Microfluidics and Their Role in Biomedical Applications
Microfluidics and Their Role in Biomedical Applications

... dimensions on the microscale. These fluids are dealt with in nano and picoliter amounts and are subject to specific properties at this level. Microfluidic devices are very promising to biomedical applications and play a key role in the future of laboratory testing. Applications in this area can rang ...
Organogels: Properties and Applications in drug delivery
Organogels: Properties and Applications in drug delivery

... Figure 2. Thermal behavior of the organogels (a) semi-solid state of the organogel at room-temperature and (b) sol state of the organogel at 60 oC 4. Common types of Organogels 4.1. Lecithin organogels Lecithin is a phospholipid, extracted from various plants and animal tissues apart from the egg yo ...
Full Article-PDF - Pharma Research Library
Full Article-PDF - Pharma Research Library

... provide protection of drugs, especially proteins that are otherwise rapidly destroyed by the body. Controlled release systems can increase patient comfort and compliance by replacing frequent (e.g., daily) doses with infrequent (once per month or less) injection. One such method is Microspheres as c ...
View Abstract - The Journal of Phytopharmacology
View Abstract - The Journal of Phytopharmacology

... on the gastric fluid. An alternative is the incorporation of matrix containing portion of liquid, which produce gas on evaporation at the body temperature. ...
Chemical Technology - Engineers Institute of India
Chemical Technology - Engineers Institute of India

... 28-B/7, Jia Sarai, Near IIT, Hauz Khas, New Delhi-110016. Ph. 011-26514888. www.engineersinstitute.com ...
Relevance of USP Methodology in the Development of a
Relevance of USP Methodology in the Development of a

... The current USP monograph for the extended release version lists five different test methods that may be used to measure drug release from a developmental formulation to match the USP specification.1 The various tests differ in media composition and pH, dissolution apparatus, presence of sinkers, an ...
Ocular Delivery of peptides and proteins
Ocular Delivery of peptides and proteins

... • Can be delivered by the ocular route and has been reported to increase blood glucose • Mol wt. is lower than insulin; may not need absorption enhancers ...
1427967058PR Aptar Pharma Twister Sine Promod 040215LV
1427967058PR Aptar Pharma Twister Sine Promod 040215LV

... “Shanghai Sine Promod Pharmaceutical Co., Ltd is one of Aptar Pharma’s key customers in China. We are particularly proud to have supported their Budesonide DPI program through the development and commercialization of Twister®, manufactured locally in our Suzhou facility. This is a very important mil ...
comparative study of natural and synthetic
comparative study of natural and synthetic

... co-solvency technique with a trial and error approach was used to develop a 10% ibuprofen ointment in petrolatum base, with the entire drug dissolved in the base. An insertion cell was used to evaluate drug release from the formulations. Further, factorial design multiple regression (FDMRA) analysis ...
Capture and immobilisation of Iodine (I2) utilising polymer
Capture and immobilisation of Iodine (I2) utilising polymer

... Electronic Supplementary Material (ESI) for Molecular Systems Design & Engineering. This journal is © The Royal Society of Chemistry 2016 ...
Delivery of Quercetin as an Antioxidant Agent to Cancer Cells... Carbon Nanotubes  Jafar Ezzati Nazhad Dolatabadi
Delivery of Quercetin as an Antioxidant Agent to Cancer Cells... Carbon Nanotubes Jafar Ezzati Nazhad Dolatabadi

... Parasitology Laboratory, Razi Vaccine and Serum Research Institute, Northwest Branch, Marand, Iran ...
05-dhamesha prakash
05-dhamesha prakash

... detoxification as catheter and suture coatings . the reconstruction of inner ear . etc. ...
A NEW TOPICAL FLUCONAZOLE MICROSPONGE LOADED HYDROGEL: PREPARATION AND CHARACTERIZATION  Research Article
A NEW TOPICAL FLUCONAZOLE MICROSPONGE LOADED HYDROGEL: PREPARATION AND CHARACTERIZATION Research Article

... profiles with the mechanisms of drug release from the drug delivery system 18, 19. In this work, zero order 18, first order 20, Higuchi 21, and Korsmeyer-Peppas 22, 23 models were applied to analyze the release profile of FLZ from the prepared microspongic gel. RESULTS AND DISCUSSION Preparation and ...
TIDES 2015 – Intranasal Drug Delivery
TIDES 2015 – Intranasal Drug Delivery

...  Painless, no needles or injections  Easy administration by patient or caregiver  Amenable to peptides, oligos and biologics ...
PDF File
PDF File

... critical to the tissue engineering and regeneration field. The delivery of biological signals from scaffolds and matrices to control these processes is thus an active research area. Our group has developed new ÔsmartÕ polymeric carriers to more effectively deliver and broaden the available types of ...
Sample pages 1 PDF
Sample pages 1 PDF

... pharmaceutical ingredients (APIs) have successfully reached the marketplace as drugs for oral transmucosal delivery. Some of these, such as nicotine and nitroglycerine, have been used in buccal/sublingual delivery dosage forms for many years. There is, thus, a disparity between the intense research ...
PHYSICAL ENHANCEMENT techniques
PHYSICAL ENHANCEMENT techniques

... The desired cells may then be selected by antibiotic resistance or another similar method . This type of transfer may also be performed between species. Thus, large numbers of plasmids may be grown in rapidly multiplying bacterial colonies and then transferred to yeast cells by electroporation for ...
Preclinical Testing Considerations:
Preclinical Testing Considerations:

... Pre-Market Development and Testing Requirements: Bench to Bedside ...
Discover Chemical Changes - gk-12
Discover Chemical Changes - gk-12

... with before and after chemical changes so that students can make the chemical changes happen themselves or at least make observations of chemical changes that have happened at each station. I have listed above 9 possible chemical changes that can be used. Students should move from station to station ...
ONdrugDELIVERY (2014), click here .
ONdrugDELIVERY (2014), click here .

... but also various applications in the field of cosmetics that have been developed. With the emerging availability of technologies enabling successful intradermal injections without special education or in-depth training, there are undoubtedly many other application areas that will generate interest f ...
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Nicholas A. Peppas



Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.
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