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cochleates
cochleates

... appropriate dosage forms for these agents are far behind the pace of the development of the new agents. This is due to their tissue impermeability and in vivo instability, low entrapment efficiency and, so on (1). Among various drug delivery routes, oral delivery is the easiest and by far the most c ...
Nano-E™: Nanoemulsion Drug Delivery System
Nano-E™: Nanoemulsion Drug Delivery System

... Key Advantages and Properties of Nano-E™ Technology • Highly versatile drug delivery platform for insoluble or soluble compounds • Small molecule and protein friendly • pH neutral, non-irritating, non-allergenic; clinically proven significant safety improvement for veinirritating drugs • For IV, IM, ...
optimising drug and device together for novel
optimising drug and device together for novel

... can master the use of a nebuliser. Various drug compounds can be nebulised, including peptides (e.g. Colistin), proteins (e.g. alpha-1 antitrypsin), or antibiotics (e.g. tobramycin), and drugs with poor lung tissue penetration (Ciclosporin A). Compared with individual actuations from a pMDI or DPI, ...
Ab Initio Quantum Chemistry: Thermochemistry and Kinetics
Ab Initio Quantum Chemistry: Thermochemistry and Kinetics

... • Principles that underlie the useful properties of atoms, molecules, macromolecules, continuum ensembles, materials • Is it chemistry? Is it physics? Is it biology? • Biochemistry? Physical chemistry? Chemical physics? • Physical organic chemistry? Biophysical chemistry? • Quantum mechanics? Statis ...
Delivering Health – Ensuring Effective Relief ACINO SWITZERLAND
Delivering Health – Ensuring Effective Relief ACINO SWITZERLAND

... Acino – Swiss quality and product excellence for international markets Switzerland, the world’s most competitive economy*, is internationally renowned for innovation and technological leadership. Over the last two decades, the Basle region, cradle of the Swiss pharmaceutical and chemical industry an ...
Microsponges as Innovative Drug Delivery Systems
Microsponges as Innovative Drug Delivery Systems

... International Journal of Pharmaceutical Sciences and Nanotechnology Volume 5 • Issue 1 • April – June 2012 ...
Chapter 6: Mesoporous Silica: An Alternative Diffusion Controlled
Chapter 6: Mesoporous Silica: An Alternative Diffusion Controlled

... Polymeric cross-linked carrier matrices, such as hydrogels and supra-molecular polymer aggregates as well as different types of microencapsulation vehicles, are typical examples of common drug delivery devices (1-4). Controlled release systems are generally classified based on their physicochemical, ...
EVALUATION OF MORINGA OLEIFERA ROOTS AND FLOWERS
EVALUATION OF MORINGA OLEIFERA ROOTS AND FLOWERS

... hydrogels and emulgels” states that developed hydrogels as well as emugels loaded with Zidovudine(AZT) and investigated the ability of hydrogels as well as emulgels to deliver the AZT via transdermal route. All the gels were evaluated for their physical properties, drug content, viscosity, pH, sprea ...
Speed control of a DC motor - UTC Engineering Lab
Speed control of a DC motor - UTC Engineering Lab

... higher education institutions, to build upon their funded research to augment the quality undergraduate education in the fields of Mathematics, Science, Engineering and Technology (MSET) .The program aims at strengthening the hands on research experience for undergraduates and high school students i ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Tremendous effort has been devoted to the development of nanocarriers for the efficient delivery of therapeutic agents to the targeted site8. In this regard macromolecules have offered tremendous potential45, but such nanodelivery systems have to meet stringent requirements if they are to be employe ...
Temperature and pH Responsive Microfibers for Controllable and
Temperature and pH Responsive Microfibers for Controllable and

... Controllable and programmable drug delivery systems have found many applications in medical and pharmaceutical sciences.[1, 2] Controlled drug delivery systems have been successfully applied to cancer treatments and tissue engineering with a better improved efficacy.[3-5] However, there are still tw ...
hydrogels: a review - Global Research Online
hydrogels: a review - Global Research Online

... release of drugs occurs through diffusion, hydrogel swelling, reversible drug-polymer interaction, degradation of labile covalent bonds. DRUG RELEASE MECHANISMS FROM HYDROGEL DEVICES Hydrogels imbibe more water than 90% of their weight due to hydrophilicity, thus differing in their release mechanism ...
view presentation - Pacira Pharmaceuticals, Inc.
view presentation - Pacira Pharmaceuticals, Inc.

... • Create value efficiently utilizing our knowledge and understanding of the acute care market and customer partnerships to develop high value added products – Commercialize DepoBupivacaine™ in the United States ...
SECTOR OVERVIEW OCULAR DRUG DELIVERY TECHNOLOGIES
SECTOR OVERVIEW OCULAR DRUG DELIVERY TECHNOLOGIES

... hydrochloride bound to ion-exchange resin particles, with the 0.25% particle formulation found to be equivalent to a 0.5% Betoptic solution. A couple of in situ gelling systems are also available, including gellan gum based Timoptic® XE and xanthan gum based Timolol GFS®, both reducing the eyedrop a ...
SUSTAINED DRUG DELIVERY TO THE POSTERIOR SEGMENTS
SUSTAINED DRUG DELIVERY TO THE POSTERIOR SEGMENTS

... lasts a week, to one that can be designed to last 3-6 months. The company invites collaborations with drug companies to codevelop ophthalmic products utilising these delivery modalities. As a CRO, Integral BioSystems offers formulation development, process engiCopyright © 2015 Frederick Furness Publ ...
Summer Engineering Research Internship for US Students (SERIUS)  2016    Host Department: Department of Chemical & Biomolecular Engineering  
Summer Engineering Research Internship for US Students (SERIUS)  2016    Host Department: Department of Chemical & Biomolecular Engineering  

... http://cheed.nus.edu.sg/stf/chewch/index.htm  Chemical engineering background  Basic idea about anaerobic digestion and gasification  ...
Slide 1
Slide 1

... • Create value efficiently utilizing our knowledge and understanding of the acute care market and customer partnerships to develop high value added products – Commercialize DepoBupivacaine™ in the United States ...
Biotransformation Problem Statement - ACE
Biotransformation Problem Statement - ACE

... chirality, functionalization). Within GSK, attrition rates from candidate selection to commercial manufacture are in excess of 95%. Certain drugs have shown some activity but have not reached exposure levels high enough to judge whether a therapeutic effect is possible, despite extremely high doses. ...
Sustained Release Dosage Forms The Sustained
Sustained Release Dosage Forms The Sustained

... The Sustained Release Concept  Sustained release, sustained action, prolonged action, controlled release, extended action, timed release, depot, ...
Formulation, Development and Characterization of Emulgel of
Formulation, Development and Characterization of Emulgel of

... delivery hydrophobic drugs. To overcome this curb an emulsion based approach is being used so that a hydrophobic therapeutic moiety can be fruitfully incorporated and delivered through gels. When gels and emulsions are used in united form the dosage forms are referred as emulgels. Piroxicam is a non ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... bucky balls can rise from drug delivery vehicles for cancer therapy to ultra hard coating and military harmor. Bucky balls are becoming powerful antioxidants and also inhibitor of HIV. [9] Hydrogels are three-dimensional and hydrophilic polymer networks capable of swelling in water or biological flu ...
vital statistics - Protagonist Therapeutics
vital statistics - Protagonist Therapeutics

... unique therapeutic potential, but, in the traditional oral formulations, peptides have serious drawbacks in stability and pharmacokinetic properties. “Our intent is to create novel chemical entities that will capture the best of both worlds, meaning the convenience and PK (pharmacokinetics) characte ...
alkermes - Moodle Lille 2
alkermes - Moodle Lille 2

... • DUREDAS™ Technology (DUal RElease Drug Absorption System) • -Bilayer tablet which can provide immediate or sustained release of two drugs or different release rates of the same drug in one dosage form. • -initially developed for OTC controlled release analgesics. In this case one layer of the tab ...
Polyesters and polyester carbonates for controlled drug delivery
Polyesters and polyester carbonates for controlled drug delivery

... CONTROLLED DRUG DELIVERY SYSTEMS ...
MICROSPONGE DRUG DELIVERY SYSTEM
MICROSPONGE DRUG DELIVERY SYSTEM

... formulation, limited chemical stability, and microbial instability. Do the MDS have a wide range of chemical stability and are they easy to formulate? • MDS have stability over a pH range of 1 - 11. • Stable up to temperature 130 o C. • Pay load is up to 50 - 60%. • Free flowing and cost effective. ...
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Nicholas A. Peppas



Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.
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