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— A review Organogels and their use in drug delivery Review
— A review Organogels and their use in drug delivery Review

... of organogel research, hundreds, if not thousands of LMW molecules with gelling properties have been discovered, most often by chance rather than design. Several extensive reviews have been published on the topic in general [3,4], as well as on more pointed discussions: fiber formation mechanisms [1 ...
phospholipids as versatile polymer in drug delivery systems
phospholipids as versatile polymer in drug delivery systems

... variety of structures depending on the specific properties of the phospholipid. These specific properties allow phospholipids to play an important role in the formation of phospholipid bilayer. Phospholipids have attracted much attention in drug delivery development, polymer science, food and cosmet ...
International Student Guide 2014
International Student Guide 2014

... scientific research, professional and consulting activities in chemical engineering, chemistry, and related fields. Teaching and education are based on modern, problem-oriented methods and provide students with analytical methodology in solving problems, but always keeping in mind the synthetic appr ...
anhydride which can be used for quantitative estimation of
anhydride which can be used for quantitative estimation of

... vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals that supply blood vessels, which makes it an efficient antihypertensive drug. It is not official in any pharmacopeia. And no spectrophotometric methods have been reported. Therefore Investigations of some new instrumen ...
Biomaterials
Biomaterials

... Wrightington Hospital in the U.K., pioneered the first total hip replacements using PTFE as the cup bearing surface. Dr. Charnley reported massive wear of the PTFE part and early clinical failure as a result of aseptic loosening. These findings, reported widely in the open literature and in later ca ...
rajiv gandhi university of health sciences
rajiv gandhi university of health sciences

... increase the stability of docetaxel in-vivo, as compared with plain liposomes, but the improvement was not more significant than PEGylated liposomes. N-palmitoyl chitosan as a new polymeric membrane to anchor liposome was useful to stabilize liposomes containing anti-tumor drug12. A study was conduc ...
Chemical Protection: In and Out of the Lab
Chemical Protection: In and Out of the Lab

... That’s right. Chemicals such as acids, bases, solvents and more are common in labs and other controlled environments. And even if you don’t directly handle dangerous chemicals in your lab, chances are good that dangerous chemicals are present somewhere in your facility or on your campus. That’s why ...
name of institution
name of institution

... subjects were randomly assigned to use either the placebo gel (control group) or the test gel(experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, plaque index and gingival bleeding index were recorded. The results did not show significant di ...
Pelagia Research Library Vesicular System
Pelagia Research Library Vesicular System

... engineering [2]. Vesicular delivery system provides an efficient method for delivery to the site of infection, leading to reduce of drug toxicity with no adverse effects. Vesicular drug delivery reduces the cost of therapy by improved bioavailability of medication, especially in case of poorly solub ...
hollow microsphere: a review
hollow microsphere: a review

... When microspheres come in contact with gastric fluid the gel formers, polysaccharides, and polymers hydrate to form a colloidal gel barrier that controls the rate of fluid penetration into the device and consequent drug release. As the exterior surface of the dosage form dissolves, the gel layer is ...
Drug Delivery System based on MEMS Technology
Drug Delivery System based on MEMS Technology

... as a hermetic seal preventing both the drug inside of the reservoir to diffuse out, and any foreign substance to penetrate inside of the reservoir. Silicon nitride was chosen as the membrane material due to its high density and use as a diffusion-stop layer. Its mechanical properties allow limited e ...
NEWER COMBINATION OF ACETYL SALICYLIC ACID AND NICOTINIC ACID IN BILAYER  MATRIX TABLETS FOR DYSLIPIDEMIA: DESIGN AND EVALUATION THEREOFF 
NEWER COMBINATION OF ACETYL SALICYLIC ACID AND NICOTINIC ACID IN BILAYER  MATRIX TABLETS FOR DYSLIPIDEMIA: DESIGN AND EVALUATION THEREOFF 

... called  flushing.  The  combination  product  of  acetyl  salicylic  acid  (ASA)  in  immediate  release  (IR)  layer  and  NA  in  sustained  release  (SR)  layer  to  design a bilayer matrix tablets (BMTs) is conceptualized based on the fact that, in clinical practice, ASA is used as “the drug” to ...
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article

... buffer  (pH  6.8)  blank.  The  drug  content  was  calculated  from  the  standard calibration curve of drug in pH 6.8 buffer. The bioadhesive  strength of the tablet estimated  using a modified physical  balance2.  Porcine  pouch  was  used  as  model  membrane  for  measurement  of  bioadhesive  ...
Biodegradable Polymers: Chemistry, Degradation and Applications
Biodegradable Polymers: Chemistry, Degradation and Applications

... Synthetic or Natural Biodegradable Polymers Why Do We Prefer Synthetic Ones? ...
III. challenges in drug delivery
III. challenges in drug delivery

... appear on the market [5]. Essentially, these new cancer treatments are designed to halt a specific cancer-causing mechanism. The difference in applying this design strategy to drug delivery is that we are not looking for ways to disable an existing mechanism but to take advantage of it. We can use t ...
Formulation and Evaluation of Trimetazidine Dihydrochloride
Formulation and Evaluation of Trimetazidine Dihydrochloride

... weighed and passed through 40#. Drug was dispersed in molten stearic acid and congealed. The mass was then screened through 20#. This was blended in a blender with diluent and Methocel® K100M. Solution of polyvinyl pyrrolidone was prepared in isopropyl alcohol and was added to form a wet mass. The w ...
Small Is Beautiful: Issues in Nanomedicine
Small Is Beautiful: Issues in Nanomedicine

... that  incorporated  nano  in  some  fashion.  This  issue  persists.  Mind  you,  these  interviews  were  taking  place  a  few  blocks  from  the  massive,  world‐class  education  and  research  complex  comprising Albany Nanotech (now SUNY Polytechnic Institute’s Colleges of Nanoscale Science  a ...
A Quick Note
A Quick Note

... for after menopause decline in circulating estrogen->reduction in vaginal blood flow->drying of vaginal tissue, rise of pH, discomfort A very low dose is recommended  targeted drug delivery to the uterus systemic delivery of drugs, via the mucous membranes ...


... upon stimulation, produced more superoxide radical than cells from healthy control subjects. It was noted that all patients included in this study were receiving j32-agonists, anticholinergics, methylxanthines, or a combination of all three. The authors state that the literature suggests that these ...
Hydroxypropyl Methyl Cellulose (HPMC)
Hydroxypropyl Methyl Cellulose (HPMC)

... Hydroxypropyl methylcellulose Ethers are highly efficient, often yielding optimum performance at a lower concentration than that required with other water-soluble polymers.The broad range of Hydroxypropyl methylcellulose is certainly one reasonit is used successfully in so many different application ...
Pharmaceutical Applications of Ispaghula Husk
Pharmaceutical Applications of Ispaghula Husk

... Natural carbohydrates have been popularly used as a material for centuries in all kinds of pharmaceutical applications. It is the world’s most abundant renewable and biodegradable polymer. Isabgol has been popularly used as therapeutic agent for the treatment of constipation, diarrhea, irritable syn ...
mucoadhesion, floating drug delivery systems
mucoadhesion, floating drug delivery systems

... this method drug carriers achieve this selectivity by the enhanced permeation and retention (EPR) depending on ...
INFLUENCE OF BLENDING OF CHITOSAN AND PULLULAN ON THEIR DRUG... BEHAVIOR: AN IN-VITRO STUDY Research Article
INFLUENCE OF BLENDING OF CHITOSAN AND PULLULAN ON THEIR DRUG... BEHAVIOR: AN IN-VITRO STUDY Research Article

... composition CP 20:80 gave minimum release rate, this may be due to the miscibility of the two polymers which hinders the diffusion of drug particles from the polymer matrix due interaction between two polymers. It indicated that blending of the polymers gave the good release profile for the drug Met ...
6Control Drug Delivery System
6Control Drug Delivery System

... primarily hydrophilic polymers having chemical or physical cross links which provides a network structure to hydrogels. Insoluble because of network structure and provides desirable protection of liable drugs, peptides and proteins ...
generic prescribing - when not to do it!
generic prescribing - when not to do it!

... Dioralyte, Electrolade ...
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Nicholas A. Peppas



Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.
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