
Synthesis of polyphosphazenes with different side
... PPZs are normally synthesized from two main raw materials: hexachlorocyclotriphosphazene (N3P3Cl6), which is used in thermal ring-opening polymerization, and phosphoranimine (Cl3P]NSiMe3), which is used in living cationic polymerization. No matter which starting material is used, the intermediate st ...
... PPZs are normally synthesized from two main raw materials: hexachlorocyclotriphosphazene (N3P3Cl6), which is used in thermal ring-opening polymerization, and phosphoranimine (Cl3P]NSiMe3), which is used in living cationic polymerization. No matter which starting material is used, the intermediate st ...
International Journal of Biomedical and Advance Research
... Polymer matrix / Drug reservoir: Polymers are the backbone of TDDS, which control the release of the drug from the device. Polymer matrix can be prepared by dispersion of drug in liquid or solid state synthetic polymer base. Polymers used in TDDS should have biocompatibility and chemical compatibili ...
... Polymer matrix / Drug reservoir: Polymers are the backbone of TDDS, which control the release of the drug from the device. Polymer matrix can be prepared by dispersion of drug in liquid or solid state synthetic polymer base. Polymers used in TDDS should have biocompatibility and chemical compatibili ...
Enhancing Transdermal Delivery of Opioid
... may have superior physicochemical properties for drug deliv ery, compared to those of the individual drug entities them ...
... may have superior physicochemical properties for drug deliv ery, compared to those of the individual drug entities them ...
APPENDIX-A CHEMICAL COMPOUNDS
... desirable to have at least 5 stages with d50 values located within the critical range from 0.5 to 5 µm aerodynamic diameter. There is a link between the cut sizes of individual impactor stages and the likely deposition sites in the respiratory tract of the particles that are size-separated, but it i ...
... desirable to have at least 5 stages with d50 values located within the critical range from 0.5 to 5 µm aerodynamic diameter. There is a link between the cut sizes of individual impactor stages and the likely deposition sites in the respiratory tract of the particles that are size-separated, but it i ...
Transdermal drug delivery: Past, present, future trends
... Ointment, used as a treatment for syphilis when Salvarsan and other arsenicals were in use, before the discovery of penicillin. Even the composition of this ointment was remarkable; it contained 50% of elemental mercury! To make the ointment, liquid mercury was first mixed with mercuric oleate, a me ...
... Ointment, used as a treatment for syphilis when Salvarsan and other arsenicals were in use, before the discovery of penicillin. Even the composition of this ointment was remarkable; it contained 50% of elemental mercury! To make the ointment, liquid mercury was first mixed with mercuric oleate, a me ...
DESIGN AND CHARACTERIZATION OF MODIFIED RELEASE ISONIAZID AND SALBUTAMOL
... The objective of the present study was to improve the therapeutic efficacy of a formulation which contains two drugs i.e. Isoniazid and Salbutamol sulphate. The present invention is to provide a dosage form comprising of an active ingredient (Isoniazid) as modified release and another active ingredi ...
... The objective of the present study was to improve the therapeutic efficacy of a formulation which contains two drugs i.e. Isoniazid and Salbutamol sulphate. The present invention is to provide a dosage form comprising of an active ingredient (Isoniazid) as modified release and another active ingredi ...
FORMULATION AND EVALUATION OF GASTRO RETENTIVE IN
... Abstract: The present study aimed at development of Ziprasidone HCl ( anti-psychotic agent) into a prolonged release oral dosage form to reduce the frequency of administration which is very difficult for psychic patients. Ziprasidone has poor bio-availability, low solubility and absorption at intes ...
... Abstract: The present study aimed at development of Ziprasidone HCl ( anti-psychotic agent) into a prolonged release oral dosage form to reduce the frequency of administration which is very difficult for psychic patients. Ziprasidone has poor bio-availability, low solubility and absorption at intes ...
Professor Yves J. Chabal, Director of the Laboratory for Surface
... A novel mass spectrometer, A. V. Ermakov, B.J. Hinch, Dept. of Chemistry and Chemical Biology Interaction of water vapor with the ruthenium (10-10) surface, T. Graber, B.V. Yakshinskiy, T.E. Madey, Dept. of Physics and Astronomy Structure sensitivity in oxidation of CO and decomposition of NH3 over ...
... A novel mass spectrometer, A. V. Ermakov, B.J. Hinch, Dept. of Chemistry and Chemical Biology Interaction of water vapor with the ruthenium (10-10) surface, T. Graber, B.V. Yakshinskiy, T.E. Madey, Dept. of Physics and Astronomy Structure sensitivity in oxidation of CO and decomposition of NH3 over ...
Room Temperature Stable Formoterol Metered Dose
... Table 3: Table of FPD (mcg) and FPF (%) after 13 months storage at 40ºC/75%RH ...
... Table 3: Table of FPD (mcg) and FPF (%) after 13 months storage at 40ºC/75%RH ...
Corporate Overview
... International Specialty Products (ISP) is a premier specialty chemical company, operating in more than 50 locations worldwide with manufacturing facilities, research laboratories, and sales and technical service offices. ISP produces a wide variety of products that have a broad range of applications ...
... International Specialty Products (ISP) is a premier specialty chemical company, operating in more than 50 locations worldwide with manufacturing facilities, research laboratories, and sales and technical service offices. ISP produces a wide variety of products that have a broad range of applications ...
Overview on Buccal Drug Delivery Systems
... or a synthetic or natural macromolecule, to mucus or an epithelial surface. When the biological substrate is attached to a mucosal layer then this phenomenon is known as mucoadhesion. The substrate possessing bioadhesive polymer can help in drug delivery for a prolonged period of time at a specific ...
... or a synthetic or natural macromolecule, to mucus or an epithelial surface. When the biological substrate is attached to a mucosal layer then this phenomenon is known as mucoadhesion. The substrate possessing bioadhesive polymer can help in drug delivery for a prolonged period of time at a specific ...
SEMINAR ON BUCCAL DRUG DELIVERY SYSTUM
... MUCOADHESIVE HYDROGEL These are hydrophilic matrices that are capable of ...
... MUCOADHESIVE HYDROGEL These are hydrophilic matrices that are capable of ...
IOSR Journal of Dental and Medical Sciences (JDMS)
... however, strangely the dental profession has failed to capitalize on its strengths and also validate its use in the management of pain in dental procedures. Currently, there is one study[13] of use of this drug in dentistry. More work is needed especially in Oral Surgery and Pedodontics. 1.3 Phentol ...
... however, strangely the dental profession has failed to capitalize on its strengths and also validate its use in the management of pain in dental procedures. Currently, there is one study[13] of use of this drug in dentistry. More work is needed especially in Oral Surgery and Pedodontics. 1.3 Phentol ...
Rodos Biotarget moves into larger laboratory and production facility
... About Biotarget GmbH Rodos Biotarget GmbH is a biopharmaceutical company that joins the ranks of industry leadership in nanocarriers for drug delivery. Rodos has developed the versatile TargoSphere® platform technology comprising biocompatible and biodegradable nanocarriers. These are designed to ac ...
... About Biotarget GmbH Rodos Biotarget GmbH is a biopharmaceutical company that joins the ranks of industry leadership in nanocarriers for drug delivery. Rodos has developed the versatile TargoSphere® platform technology comprising biocompatible and biodegradable nanocarriers. These are designed to ac ...
incorporation of anti-cancer drug on mesoporous silica
... reaching the desired temperature, to this mixture was added 1.34 mL of tetraethoxysilane TEOS (Sigma Aldrich 98%). The mixture was left under stirring for 2 hours, maintaining the temperature of 80 °C. After this time, heating and stirring were turned off and the mixture was allowed to stand to reac ...
... reaching the desired temperature, to this mixture was added 1.34 mL of tetraethoxysilane TEOS (Sigma Aldrich 98%). The mixture was left under stirring for 2 hours, maintaining the temperature of 80 °C. After this time, heating and stirring were turned off and the mixture was allowed to stand to reac ...
For more information on accessing electronic
... Source:Advanced Drug Delivery Reviews, Volume 65, Issues 13–14 Author(s): Yi Zhao , Daria Y. Alakhova , Alexander V. Kabanov Most tumors are heterogeneous and many cancers contain small population of highly tumorigenic and intrinsically drug resistant cancer stem cells (CSCs). Like normal stem cell, ...
... Source:Advanced Drug Delivery Reviews, Volume 65, Issues 13–14 Author(s): Yi Zhao , Daria Y. Alakhova , Alexander V. Kabanov Most tumors are heterogeneous and many cancers contain small population of highly tumorigenic and intrinsically drug resistant cancer stem cells (CSCs). Like normal stem cell, ...
The Role of Molecular Imaging in Drug Delivery
... and pharmacodynamic properties of therapeutic agents. For example, paclitaxel (Taxol), a complex taxane diterpene, is a potent antitumour agent that has been commonly used in the treatment of various types of cancer.6 However, the use of paclitaxel is limited by the drug’s toxicity (i.e. acute myelo ...
... and pharmacodynamic properties of therapeutic agents. For example, paclitaxel (Taxol), a complex taxane diterpene, is a potent antitumour agent that has been commonly used in the treatment of various types of cancer.6 However, the use of paclitaxel is limited by the drug’s toxicity (i.e. acute myelo ...
FORMULATION AND EVALUATION OF THERMOSENSITIVE IN SITU GEL OF SALBUTAMOL
... This study aimed to formulate and evaluate Nasal drug delivery system containing Salbutamol Sulphate was prepared for improving the bioavailability & sustaining the drug release. Salbutamol sulphate is a selective β2 adrenoreceptor agonist and rapidly absorbed from gastro intestinal tract but it is ...
... This study aimed to formulate and evaluate Nasal drug delivery system containing Salbutamol Sulphate was prepared for improving the bioavailability & sustaining the drug release. Salbutamol sulphate is a selective β2 adrenoreceptor agonist and rapidly absorbed from gastro intestinal tract but it is ...
FORMULATION AND EVALUATION OF OLMESARTAN MEDOXOMIL FLOATING TABLETS
... Conclusion: The drug release from the tablet was sustained and non-fickian transport of drug from the tablet was confirmed. Keywords: Olmesartan Medoxomil, floating tablet, In vitro buoyancy, Gas forming agents. ...
... Conclusion: The drug release from the tablet was sustained and non-fickian transport of drug from the tablet was confirmed. Keywords: Olmesartan Medoxomil, floating tablet, In vitro buoyancy, Gas forming agents. ...
Crosslinked hydrogels—a promising class of insoluble solid
... 2211-3835 & 2014 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. Open access under CC BY-NC-ND license. http://dx.doi.org/10.1016/j.apsb.2013.12.002 ...
... 2211-3835 & 2014 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. Open access under CC BY-NC-ND license. http://dx.doi.org/10.1016/j.apsb.2013.12.002 ...
Role of nanotechnology in targeted drug delivery and imaging: T
... a recipient of the University of Illinois-Chicago Fellowship 2004-2005. T Corresponding author. Department of Biopharmaceutical Sciences (M/C 865), College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612-7231, USA. E-mail address: [email protected] (H. Onyuksel). 1549-9634/$ – see fron ...
... a recipient of the University of Illinois-Chicago Fellowship 2004-2005. T Corresponding author. Department of Biopharmaceutical Sciences (M/C 865), College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612-7231, USA. E-mail address: [email protected] (H. Onyuksel). 1549-9634/$ – see fron ...
Development of a 100 mg theophylline sustained
... alto contenido) y X3 (fracción de la totalidad de la masa de las tabletas que corresponde al granulado de bajo contenido de polímero). También se estudió la cinética de liberación in vitro de patrones de reconocido prestigio como Theo-Dur de Key Pharmaceuticals y Slo-Bid de Rhone Poulenc. En base a ...
... alto contenido) y X3 (fracción de la totalidad de la masa de las tabletas que corresponde al granulado de bajo contenido de polímero). También se estudió la cinética de liberación in vitro de patrones de reconocido prestigio como Theo-Dur de Key Pharmaceuticals y Slo-Bid de Rhone Poulenc. En base a ...
Dissolution behavior of poly vinyl alcohol in water and its effect on
... fibroin/poly(vinyl alcohol) photocrosslinked hydrogels for delivery of macromolecular drugs. Acta Biomaterialia. ...
... fibroin/poly(vinyl alcohol) photocrosslinked hydrogels for delivery of macromolecular drugs. Acta Biomaterialia. ...
MICRONEEDLES: AN INNOVATIVE APPROACH TO TRANSDERMAL DELIVERY- A REVIEW Review Article
... skin [3]. These are generally describes as the devices, enclosing drug molecules of defined surface area that delivers the predetermined amount of drug to the intact skin surface at a predetermined rate [4]. Transdermal delivery of systemically acting drugs uses the skin as an alternative route [5]. ...
... skin [3]. These are generally describes as the devices, enclosing drug molecules of defined surface area that delivers the predetermined amount of drug to the intact skin surface at a predetermined rate [4]. Transdermal delivery of systemically acting drugs uses the skin as an alternative route [5]. ...
Nicholas A. Peppas

Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.