Preparation, characterization, and in vivo evaluation of - e
... layer hydration technique for the preparation of liposomes by using cholesterol, polyethylene glycol, and 1,2-distearyl-sn-glycero-3-phosphocholine (DSPC). The prepared liposomes were characterized by determining particle size, shape, surface morphology, zeta potential, encapsulation efficiency, and ...
... layer hydration technique for the preparation of liposomes by using cholesterol, polyethylene glycol, and 1,2-distearyl-sn-glycero-3-phosphocholine (DSPC). The prepared liposomes were characterized by determining particle size, shape, surface morphology, zeta potential, encapsulation efficiency, and ...
Graphene Oxide for Biomedical Applications
... tumor cells is possible. However, there is a concern on toxicity of this nanocomposites [3]. A core-shell nanocomposite of chitosan based polyseudorotaxane shell and (Fe3O4@GO@mSiO2) core showed excellent pH dependent release. The extent of drug release can be controlled by changing the pH and the b ...
... tumor cells is possible. However, there is a concern on toxicity of this nanocomposites [3]. A core-shell nanocomposite of chitosan based polyseudorotaxane shell and (Fe3O4@GO@mSiO2) core showed excellent pH dependent release. The extent of drug release can be controlled by changing the pH and the b ...
Enhanced dissolution and oral bioavailability of coenzyme Q10 in
... to select the most suitable CyD for the drug, because the solubilization effect of CyDs is dependent on their cavity size. In a previous paper [8], we reported that 2,6-di-Omethyl-β-CyD (DM-β-CyD) significantly enhances the low solubility and oral bioavailability of CoQ10. However, ...
... to select the most suitable CyD for the drug, because the solubilization effect of CyDs is dependent on their cavity size. In a previous paper [8], we reported that 2,6-di-Omethyl-β-CyD (DM-β-CyD) significantly enhances the low solubility and oral bioavailability of CoQ10. However, ...
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF ONDANSETRON HYDROCHLORIDE Research Article
... state, which causes the molecules to be spaced further apart than in crystal. Hence the specific volume is increased and the density decreased compared to that of crystal, which leads to the absorption of vapor into their interstices. All the formulations were permeable to water vapor. In-Vitro Diss ...
... state, which causes the molecules to be spaced further apart than in crystal. Hence the specific volume is increased and the density decreased compared to that of crystal, which leads to the absorption of vapor into their interstices. All the formulations were permeable to water vapor. In-Vitro Diss ...
et al. Madhu E. Nicholas* , Shanker Panaganti , L. Prabakaran
... issues associated with premature release of drug in the upper parts of the Gastrointestinal tract, namely stomach and small intestine. Colon targeted drug delivery would ensures direct treatment at the disease site, lower dosing and less systemic side effects. In addition to restricted therapy, the ...
... issues associated with premature release of drug in the upper parts of the Gastrointestinal tract, namely stomach and small intestine. Colon targeted drug delivery would ensures direct treatment at the disease site, lower dosing and less systemic side effects. In addition to restricted therapy, the ...
Polymer in EFKA -4550
... coating (up to 50%) may be lost through overspray. However, the notified polymer will be a component of coating formulations, which will be used in highly automated facilities dedicated to high volume spray application of surface coatings. These facilities are fitted with recirculation pumps and oth ...
... coating (up to 50%) may be lost through overspray. However, the notified polymer will be a component of coating formulations, which will be used in highly automated facilities dedicated to high volume spray application of surface coatings. These facilities are fitted with recirculation pumps and oth ...
Frequently Asked Questions
... as a high molecular weight polymer of acrylic acid crosslinked with allyl ethers of polyalcohols. The United States Pharmacopeia (USP) and European Pharmacopeia (Ph. Eur.) include various carbomer monographs. 5. What is the current compendial nomenclature that applies to Carbopol® polymers? The Eur ...
... as a high molecular weight polymer of acrylic acid crosslinked with allyl ethers of polyalcohols. The United States Pharmacopeia (USP) and European Pharmacopeia (Ph. Eur.) include various carbomer monographs. 5. What is the current compendial nomenclature that applies to Carbopol® polymers? The Eur ...
SOLUBILITY AND DISSOLUTION IMPROVEMENT OF KETOPROFEN BY SOLID DISPERSION IN POLYMER AND SURFACTANT USING SOLVENT EVAPORATION METHOD
... anti‐inflammatory drug (NSAID) with good analgesic properties widely used in the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and acute gouty arthritis. However, it has poor water solubility (0.13 mg mL‐1 at 25°C) which may predispose to formu ...
... anti‐inflammatory drug (NSAID) with good analgesic properties widely used in the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and acute gouty arthritis. However, it has poor water solubility (0.13 mg mL‐1 at 25°C) which may predispose to formu ...
An Unified Approach to Thermodynamics of Power Yield in Thermal
... whose derivations and applications were originated in our previous work [9, 10]. Since diverse control variables of heat and mass transfer can accomplish the task of a sustainable energy conversion, alternative (more traditional) controls are also possible. However, the mathematical formulas are the ...
... whose derivations and applications were originated in our previous work [9, 10]. Since diverse control variables of heat and mass transfer can accomplish the task of a sustainable energy conversion, alternative (more traditional) controls are also possible. However, the mathematical formulas are the ...
Author`s personal copy
... Osmotic pumps belong to the class of rate-controlled systems providing continuous delivery and offer a set of distinct advantages. First and foremost this includes the simple principle of operation requiring no electric energy. Hence, pump designs can be kept simple resulting in increased robustness ...
... Osmotic pumps belong to the class of rate-controlled systems providing continuous delivery and offer a set of distinct advantages. First and foremost this includes the simple principle of operation requiring no electric energy. Hence, pump designs can be kept simple resulting in increased robustness ...
Provisional PDF - Nanoscale Research Letters
... To compare the pharmacokinetics of Qu-PMs with those of pure Qu after oral administration, an animal experiment was in favor of the Ethical Committee of the Sun Yat-sen University (Guangzhou, China) and performed in accordance with the National Institute of Health and Nutrition Guidelines for the Ca ...
... To compare the pharmacokinetics of Qu-PMs with those of pure Qu after oral administration, an animal experiment was in favor of the Ethical Committee of the Sun Yat-sen University (Guangzhou, China) and performed in accordance with the National Institute of Health and Nutrition Guidelines for the Ca ...
Role of Novel Drug Delivery Systems in
... directly corresponding to the surface area as particles are their small sizes, which make them a favorable material for reduced to a minute size. Hence, the saturation solubility biomedical applications. Nanoparticles have greater and dissolution rate of poorly water soluble drugs is surface area to ...
... directly corresponding to the surface area as particles are their small sizes, which make them a favorable material for reduced to a minute size. Hence, the saturation solubility biomedical applications. Nanoparticles have greater and dissolution rate of poorly water soluble drugs is surface area to ...
Nanomedicine Taxonomy
... creation of new knowledge and its translation into improved health for Canadians, more effective health services and products and a strengthened health care system. Health care is a highly visible and growing concern for governments, taxpayers and the general population. With many countries includin ...
... creation of new knowledge and its translation into improved health for Canadians, more effective health services and products and a strengthened health care system. Health care is a highly visible and growing concern for governments, taxpayers and the general population. With many countries includin ...
FORMULATION AND EVALUATION OF FLUCONAZOLE TOPICAL GEL Research Article DOAA A. HELAL
... Fluconazole is available commercially as tablets and injections only in spite of its well known adverse effects including nausea, vomiting, bloating and abdominal discomfort. In order to bypass these disadvantages, the gel formulations have been proposed as topical application. ...
... Fluconazole is available commercially as tablets and injections only in spite of its well known adverse effects including nausea, vomiting, bloating and abdominal discomfort. In order to bypass these disadvantages, the gel formulations have been proposed as topical application. ...
2014-Chapel_Hill
... Hill, NC. The history of nanoDDS goes back to January 2003, when Dr. Alexander Kabanov and Dr. Kazunori Kataoka have organized the first nanomedicine meeting in the United States – “The Nanomedicine and Drug Delivery Symposium”. Since then nanoDDS has been held annually in different locations across ...
... Hill, NC. The history of nanoDDS goes back to January 2003, when Dr. Alexander Kabanov and Dr. Kazunori Kataoka have organized the first nanomedicine meeting in the United States – “The Nanomedicine and Drug Delivery Symposium”. Since then nanoDDS has been held annually in different locations across ...
FORMULATION AND EVALUATION OF TASTE MASKED ORAL DISPERSIBLE TABLETS OF
... preferably in less than 40 seconds, forming a suspension which is easy to swallow 7. Some drugs are absorbed from the mouth, pharynx and esophagus as the saliva passes down into the stomach. In such cases bioavailability of drug is significantly greater than those observed from conventional tablet d ...
... preferably in less than 40 seconds, forming a suspension which is easy to swallow 7. Some drugs are absorbed from the mouth, pharynx and esophagus as the saliva passes down into the stomach. In such cases bioavailability of drug is significantly greater than those observed from conventional tablet d ...
IN VITRO Original Article ENKELEJDA GOCI
... Objective: The present research has been undertaken with the aim to develop a topical gel of diclofenac sodium (DS) 1%, evaluation of its physicochemical characteristics and in vitro drug release through pig skin using vertical diffusion cell. Methods: In the presented work was prepared a hydrophili ...
... Objective: The present research has been undertaken with the aim to develop a topical gel of diclofenac sodium (DS) 1%, evaluation of its physicochemical characteristics and in vitro drug release through pig skin using vertical diffusion cell. Methods: In the presented work was prepared a hydrophili ...
rajiv gandhi university of health sciences
... patient and the clinician alike. However, oral administration of drugs has disadvantages such as hepatic first pass metabolism and enzymatic degradation within the gastro intestinal (GIT), that prohibit oral administration of certain classes of drugs especially peptides and proteins. Trans mucosal r ...
... patient and the clinician alike. However, oral administration of drugs has disadvantages such as hepatic first pass metabolism and enzymatic degradation within the gastro intestinal (GIT), that prohibit oral administration of certain classes of drugs especially peptides and proteins. Trans mucosal r ...
ACCELERATED STABILITY TESTING OF BETAMETHASONE DIPROPIONATE NANOEMULSION
... Accelerated stability studies were also performed on optimized BD nanoemulsion as per international conference on harmonization (ICH) guidelines. Stability studies on optimized nanoemulsion were performed by keeping the sample at refrigerator temperature (4oC) and room temperature (25oC). These stud ...
... Accelerated stability studies were also performed on optimized BD nanoemulsion as per international conference on harmonization (ICH) guidelines. Stability studies on optimized nanoemulsion were performed by keeping the sample at refrigerator temperature (4oC) and room temperature (25oC). These stud ...
2014 - Atiner
... Athens Institute for Education and Research. In total there were 33 papers, coming from 15 different countries (Austria, Brazil, Canada, China, Denmark, Egypt, India, Kingdom of Bahrain, Malaysia, Portugal, Saudi Arabia, Singapore, Turkey, UK, USA). The conference was organized into 8 sessions that ...
... Athens Institute for Education and Research. In total there were 33 papers, coming from 15 different countries (Austria, Brazil, Canada, China, Denmark, Egypt, India, Kingdom of Bahrain, Malaysia, Portugal, Saudi Arabia, Singapore, Turkey, UK, USA). The conference was organized into 8 sessions that ...
FORMULATION AND IN-VITRO EVALUATION OF THERMOREVERSIBLE RIZATRIPTAN BENZOATE NASAL GEL Research Article
... for the treatment of chronic diseases. Therefore an alternative route of administration would be preferred. For the past few decades, the transdermal route has been explored for a number of drugs, but its use is limited due to low permeability of the skin to many drugs Nonparenteral routes for drug ...
... for the treatment of chronic diseases. Therefore an alternative route of administration would be preferred. For the past few decades, the transdermal route has been explored for a number of drugs, but its use is limited due to low permeability of the skin to many drugs Nonparenteral routes for drug ...
FORMULATION AND EVALUATION OF ERGOTAMINE TARTRATE LYOPHILIZED NASAL INSERT
... Drug Content of Inserts Each insert was dissolved in 50 ml Sorensen's phosphate buffer, (PH 7.5) the absorbance of the solution was then measured spectrophotometrically at 305 nm. The test was done on 10 individual inserts [8]. Scanning Electron Microscopy of inserts Inserts were cut with a razor bl ...
... Drug Content of Inserts Each insert was dissolved in 50 ml Sorensen's phosphate buffer, (PH 7.5) the absorbance of the solution was then measured spectrophotometrically at 305 nm. The test was done on 10 individual inserts [8]. Scanning Electron Microscopy of inserts Inserts were cut with a razor bl ...
Formulation
... In vitro dissolution studies were carried out in the absence of rat cecal content medium, the percent drug released from aceclofenac tablets coated with coat formulation CT1,CT2 and CT3 at the end of 24 h was found to be only 27.82%,30.26% and 32.52% respectively and the coat was remained intact. In ...
... In vitro dissolution studies were carried out in the absence of rat cecal content medium, the percent drug released from aceclofenac tablets coated with coat formulation CT1,CT2 and CT3 at the end of 24 h was found to be only 27.82%,30.26% and 32.52% respectively and the coat was remained intact. In ...
Association in Solution III - Engineering Conferences International
... Hydrophobic interactions, driven by the inability of water molecules to hydrogen bond in the vicinity of hydrophobic molecules and surfaces resulting in strong, long range attractive interactions between hydrophobic moieties, are ubiquitous in the self-assembly of complex structures and many physica ...
... Hydrophobic interactions, driven by the inability of water molecules to hydrogen bond in the vicinity of hydrophobic molecules and surfaces resulting in strong, long range attractive interactions between hydrophobic moieties, are ubiquitous in the self-assembly of complex structures and many physica ...
Synthesis of polyphosphazenes with different side
... PPZs are normally synthesized from two main raw materials: hexachlorocyclotriphosphazene (N3P3Cl6), which is used in thermal ring-opening polymerization, and phosphoranimine (Cl3P]NSiMe3), which is used in living cationic polymerization. No matter which starting material is used, the intermediate st ...
... PPZs are normally synthesized from two main raw materials: hexachlorocyclotriphosphazene (N3P3Cl6), which is used in thermal ring-opening polymerization, and phosphoranimine (Cl3P]NSiMe3), which is used in living cationic polymerization. No matter which starting material is used, the intermediate st ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.