Modification of Microbial Polyacids for Drug Delivery Systems U
... observed by scanning electron microscopy and their size and surface charge characterized by dynamic light scattering and ζ-potential measurement. Assays of drug encapsulation and release were also performed and cytotoxicity tests were done on cancer cell lines. Nanoparticles (100-300 nm aprox.) were ...
... observed by scanning electron microscopy and their size and surface charge characterized by dynamic light scattering and ζ-potential measurement. Assays of drug encapsulation and release were also performed and cytotoxicity tests were done on cancer cell lines. Nanoparticles (100-300 nm aprox.) were ...
Spreading of Semisolid Formulations: An Update
... their effect on the formulation contained within. In another study they evaluated the increase in tackiness that occurs in some formulations as they dry and devised an empirical test to measure the cohesive–adhesive capability of skin surface during absorption after the rub-in. Several authors have ...
... their effect on the formulation contained within. In another study they evaluated the increase in tackiness that occurs in some formulations as they dry and devised an empirical test to measure the cohesive–adhesive capability of skin surface during absorption after the rub-in. Several authors have ...
Liposomal drug delivery systems: From concept to clinical applications
... this paper to find those early references and give credit to the liposome pioneers — and put their contributions into context. It is our intent to focus on the early work in the liposome field, especially work done with small molecule therapeutics, and we apologize to our many colleagues whose more re ...
... this paper to find those early references and give credit to the liposome pioneers — and put their contributions into context. It is our intent to focus on the early work in the liposome field, especially work done with small molecule therapeutics, and we apologize to our many colleagues whose more re ...
Manal Alsaadi Research Day Poster
... is the leading cause of cancer death claiming the lives of 1.3 million patients a year worldwide [1]. Lung cancer is mainly treated by cisplatin, where it is presently administered as an intravenous infusion over 6-8 hours. This results in entire body exposure leading to undesirable and chronic side ...
... is the leading cause of cancer death claiming the lives of 1.3 million patients a year worldwide [1]. Lung cancer is mainly treated by cisplatin, where it is presently administered as an intravenous infusion over 6-8 hours. This results in entire body exposure leading to undesirable and chronic side ...
analysis of polymers by gpc/sec pharmaceutical applications
... The Quality by Design (QbD) concept was developed by J. M. Juran over the past 20 years. Juran’s approach focused on planning for quality as part of the manufacturing process, i.e. establishing processes at the outset in such a way that quality problems were designed out. In effect, product developm ...
... The Quality by Design (QbD) concept was developed by J. M. Juran over the past 20 years. Juran’s approach focused on planning for quality as part of the manufacturing process, i.e. establishing processes at the outset in such a way that quality problems were designed out. In effect, product developm ...
Supporting Information (SI) Nanomicelle formulation for topical
... Chuanlong Guo1,+, Yan Zhang2,+, Zhao Yang2, Mengshuang Li1, Fengjie Li1, Fenghua Cui1, Ting Liu1, Weiyun Shi1, and Xianggen Wu1,* ...
... Chuanlong Guo1,+, Yan Zhang2,+, Zhao Yang2, Mengshuang Li1, Fengjie Li1, Fenghua Cui1, Ting Liu1, Weiyun Shi1, and Xianggen Wu1,* ...
Cellulose, Chitosan, and Keratin Composite Materials. Controlled
... regenerative nature of wools and hairs coupled with the ability to be readily converted into biomaterials for the control of several biological processes have made KER a subject of intense study for various biomedical applications including scaffolds for tissue engineering and drug delivery.1−14 Unfo ...
... regenerative nature of wools and hairs coupled with the ability to be readily converted into biomaterials for the control of several biological processes have made KER a subject of intense study for various biomedical applications including scaffolds for tissue engineering and drug delivery.1−14 Unfo ...
Development of nanovectors for the targeted drug delivery of antimalarials Patricia Urbán
... WARNING. On having consulted this thesis you’re accepting the following use conditions: Spreading this thesis by the TDX (www.tdx.cat) service has been authorized by the titular of the intellectual property rights only for private uses placed in investigation and teaching activities. Reproduction wi ...
... WARNING. On having consulted this thesis you’re accepting the following use conditions: Spreading this thesis by the TDX (www.tdx.cat) service has been authorized by the titular of the intellectual property rights only for private uses placed in investigation and teaching activities. Reproduction wi ...
![[27] Kumar, RMNV- Eds. Handbook of Particulate Drug Delivery,2008](http://s1.studyres.com/store/data/002367987_1-7fa2f44d01cdb2370574c079aacf4d42-300x300.png)
[27] Kumar, RMNV- Eds. Handbook of Particulate Drug Delivery,2008
... The molecular basis for the essential role of cholesterol in mammalian (and other cholesterolrequiring) cells has long been the object of intense interest. Cholesterol has been found to modulate the function of membrane proteins critical to cellular function. Current literature supports two mechanis ...
... The molecular basis for the essential role of cholesterol in mammalian (and other cholesterolrequiring) cells has long been the object of intense interest. Cholesterol has been found to modulate the function of membrane proteins critical to cellular function. Current literature supports two mechanis ...
Aerosol delivery from spacers in wheezy infants: a daily life...
... dose, for all spacers is shown in figure 1. Median (range) dose delivery was 34% (3±59), 22% (1±49) and 41% (12± 55) for the Nebuchamber, the nonDC-Babyhaler, and DC-Babyhaler respectively. Median dose delivery for the Nebuchamber was significantly higher than for the nonDC-Babyhaler (p=0.03) but lo ...
... dose, for all spacers is shown in figure 1. Median (range) dose delivery was 34% (3±59), 22% (1±49) and 41% (12± 55) for the Nebuchamber, the nonDC-Babyhaler, and DC-Babyhaler respectively. Median dose delivery for the Nebuchamber was significantly higher than for the nonDC-Babyhaler (p=0.03) but lo ...
Summer 2014 Commencement Program
... Akron by the Alumni Association on Founders Day 1970, in recognition of the University’s founding 100 years earlier as Buchtel College. Since ancient times, maces have been symbols of authority for many academic and governmental bodies. The University of Akron’s Ceremonial Mace is carried by the Un ...
... Akron by the Alumni Association on Founders Day 1970, in recognition of the University’s founding 100 years earlier as Buchtel College. Since ancient times, maces have been symbols of authority for many academic and governmental bodies. The University of Akron’s Ceremonial Mace is carried by the Un ...
Effect of Acid, Base, Temperature and U.V Light on Amlodipine
... It inhibits the entrance of extracellular Ca into the peripheral smooth muscles and cardiac muscles by inhibiting HMG-CoA reductase [2]. It is used as an antihypertensive agent and very successfully for treatment of cardiovascular diseases and hypertension [3]. Other members of the class include nim ...
... It inhibits the entrance of extracellular Ca into the peripheral smooth muscles and cardiac muscles by inhibiting HMG-CoA reductase [2]. It is used as an antihypertensive agent and very successfully for treatment of cardiovascular diseases and hypertension [3]. Other members of the class include nim ...
PDF - Innovare Academic Sciences
... Successful oral delivery of drugs has always remained a challenge to the drug delivery field, since approximately 40% of the new drug candidates have poor water solubility, and thus oral delivery is frequently associated with implications of low bioavailability. Today, a large percent of the new che ...
... Successful oral delivery of drugs has always remained a challenge to the drug delivery field, since approximately 40% of the new drug candidates have poor water solubility, and thus oral delivery is frequently associated with implications of low bioavailability. Today, a large percent of the new che ...
National Conference on “Recent Advances in Herbal Drug Technology”
... Abstract: Tectona grandis Linn. (Verbenaceae) is an important medicinal plant commonly known as sagwan. The bark of this plant is acrid and useful in the treatment of bronchitis. Aim of the present study is to validate traditional asthmatic action of the bark. Dried powdered bark was extracted using ...
... Abstract: Tectona grandis Linn. (Verbenaceae) is an important medicinal plant commonly known as sagwan. The bark of this plant is acrid and useful in the treatment of bronchitis. Aim of the present study is to validate traditional asthmatic action of the bark. Dried powdered bark was extracted using ...
![Cucurbit[n]urils as excipients in pharmaceutical dosage forms](http://s1.studyres.com/store/data/005393778_1-462b4ddd8a98f7dba6c184d59041de9f-300x300.png)
Cucurbit[n]urils as excipients in pharmaceutical dosage forms
... macrocycles that are able to form host-guest complexes with a variety of molecules (1). They have a range of applications, including: waste remediation, chromatography, molecular switches and handcuffs, diagnostics, catalysis, and solid-state chemistry. One of the most studied applications of cucurb ...
... macrocycles that are able to form host-guest complexes with a variety of molecules (1). They have a range of applications, including: waste remediation, chromatography, molecular switches and handcuffs, diagnostics, catalysis, and solid-state chemistry. One of the most studied applications of cucurb ...
formulation and evaluation of ibuprofen suppositories
... Mucosal drug delivery technique has received wide interest by many researchers. The advantages of this route over other routs of administration include avoiding the first pass metabolism and minimizing gastric irritation. The rectum has a good blood supply, absence of villi and a relatively small su ...
... Mucosal drug delivery technique has received wide interest by many researchers. The advantages of this route over other routs of administration include avoiding the first pass metabolism and minimizing gastric irritation. The rectum has a good blood supply, absence of villi and a relatively small su ...
Physicochemical characterization of meloxicam–mannitol binary
... ambiguities can be moderated or even eliminated if convenient constraints can be used [18–20]. Tauler and coworkers developed a Matlab code for MCR-ALS with some constraints [24]. 3. Results and discussion 3.1. Particle size and specific surface area ...
... ambiguities can be moderated or even eliminated if convenient constraints can be used [18–20]. Tauler and coworkers developed a Matlab code for MCR-ALS with some constraints [24]. 3. Results and discussion 3.1. Particle size and specific surface area ...
Full-Text PDF
... and able to load guest molecules in their lipophilic inner cavity via non-covalent inclusion interactions. As well as other nanocarriers, the use of CD can increase drug solubility, bioavailability, safety, and stability of drug formulations [60]. Polymers provide even more versatility in nanocarrie ...
... and able to load guest molecules in their lipophilic inner cavity via non-covalent inclusion interactions. As well as other nanocarriers, the use of CD can increase drug solubility, bioavailability, safety, and stability of drug formulations [60]. Polymers provide even more versatility in nanocarrie ...
CHITOSAN LOADED MICROSPHERES AS AN OCULAR DELIVERY SYSTEM FOR ACYCLOVIR S.SELVARAJ
... The aim of the present investigation was to evaluate the potential use of chitosan microspheres for ocular delivery of acyclovir. The topical application of acyclovir as eye ointment remains a concern for effective management of various ocular viral diseases owing to poor ocular drug bioavailability ...
... The aim of the present investigation was to evaluate the potential use of chitosan microspheres for ocular delivery of acyclovir. The topical application of acyclovir as eye ointment remains a concern for effective management of various ocular viral diseases owing to poor ocular drug bioavailability ...
Dow Corning Silicones in Pharmaceutical Applications
... [6], with viscosities between 10 to 100,000 mPa.s. These have not shown toxicity during administration via typical exposure routes. Due to their high molecular weight, they are not absorbed in the G.I. tract and are excreted without modification, nor are they absorbed through the skin (12). In vitro ...
... [6], with viscosities between 10 to 100,000 mPa.s. These have not shown toxicity during administration via typical exposure routes. Due to their high molecular weight, they are not absorbed in the G.I. tract and are excreted without modification, nor are they absorbed through the skin (12). In vitro ...
Design and physicochemical characterisation of novel
... facilitated delivery of low molecular weight, high dose drugs. Ibuprofen sodium was used as the model here and was successfully formulated at approximately 50% w/w in the dry state using the copolymer poly(methylvinylether/maleic acid). These MNs were robust and effectively penetrated skin in vitro, ...
... facilitated delivery of low molecular weight, high dose drugs. Ibuprofen sodium was used as the model here and was successfully formulated at approximately 50% w/w in the dry state using the copolymer poly(methylvinylether/maleic acid). These MNs were robust and effectively penetrated skin in vitro, ...
ABSTRACT Title of Document:
... me this opportunity to pursue a research project at the NIH, which has been an invaluable experience. I also thank Dr. Michael Robinson for being a mentor and for teaching me the current needs in ocular drug delivery. Dr. Karl Csaky has contributed significantly to this project financially and also ...
... me this opportunity to pursue a research project at the NIH, which has been an invaluable experience. I also thank Dr. Michael Robinson for being a mentor and for teaching me the current needs in ocular drug delivery. Dr. Karl Csaky has contributed significantly to this project financially and also ...
Effect of inorganic salts on the inclusion complex
... CDs. This topic is recently of particular interest for formulators since there are several granted patents and published patent applications on commercially available CD derivatives with certain intrinsic ion contents (in particular chloride and phosphate), such as US patents US7635773, US8410077, U ...
... CDs. This topic is recently of particular interest for formulators since there are several granted patents and published patent applications on commercially available CD derivatives with certain intrinsic ion contents (in particular chloride and phosphate), such as US patents US7635773, US8410077, U ...
STUDY OF EFFECTS OF POSTCOMPRESSION CURING ON KOLLIDON SR BASED FLOATING TABLETS
... of Kollidon® SR. The curing duration studies concluded that a few hours at 60°C is a sufficient curing condition for such tablets.15 Thus in order to get tablets with stabilized dissolution pattern and improved physical stability, tablets were subjected to curing at 60°C for 1 ...
... of Kollidon® SR. The curing duration studies concluded that a few hours at 60°C is a sufficient curing condition for such tablets.15 Thus in order to get tablets with stabilized dissolution pattern and improved physical stability, tablets were subjected to curing at 60°C for 1 ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.