PDF - Oxford Academic - Oxford University Press
... effect of drug intake) yields the opposite effect. Thus, this work suggests a circuit scenario according to which endogenous DSI is beneficial for, whereas an exogenous drug such as marijuana is detrimental to, working memory and possibly other prefrontal functions. Keywords: continuous attractor ne ...
... effect of drug intake) yields the opposite effect. Thus, this work suggests a circuit scenario according to which endogenous DSI is beneficial for, whereas an exogenous drug such as marijuana is detrimental to, working memory and possibly other prefrontal functions. Keywords: continuous attractor ne ...
Fine-scale specificity of cortical networks depends on inhibitory cell
... neurons, differential interference contrast (DIC) optics were used to target recordings to one pyramidal neuron and one inhibitory interneuron (Fig. 1a,b). Inhibitory neurons were classified as either fast-spiking or adapting on the basis of their intrinsic firing properties in response to intracell ...
... neurons, differential interference contrast (DIC) optics were used to target recordings to one pyramidal neuron and one inhibitory interneuron (Fig. 1a,b). Inhibitory neurons were classified as either fast-spiking or adapting on the basis of their intrinsic firing properties in response to intracell ...
Metabolism of amino acids
... Amino nitrogen released from carbon sceletons of AAs can be transported in blood as a) NH4+ physiologically up to 35 µmol/l (NH3 + H + b) alanine ...
... Amino nitrogen released from carbon sceletons of AAs can be transported in blood as a) NH4+ physiologically up to 35 µmol/l (NH3 + H + b) alanine ...
Mitochondrial Functions in Mood Disorders
... tion, protein malformation, decrease of ATP production, and increase of oxygen radical generation. These processes can lead to atrophy or death of neurons [27-28]. Different stimu‐ li, such as hypoxia-ischemia, seizure and hypoglycemia, all activate this pathway. Thus, en‐ hancing mitochondrial func ...
... tion, protein malformation, decrease of ATP production, and increase of oxygen radical generation. These processes can lead to atrophy or death of neurons [27-28]. Different stimu‐ li, such as hypoxia-ischemia, seizure and hypoglycemia, all activate this pathway. Thus, en‐ hancing mitochondrial func ...
Understanding Circuit Dynamics Using the Stomatogastric Nervous
... 5. It is routinely possible to obtain simultaneous recordings of most, if not all, relevant circuit neurons, using a combination of intracellular and extracellular recordings. Routine STNS experiments include 4 simultaneous intracellular recordings and 8–12 extracellular nerve recordings. 6. The lar ...
... 5. It is routinely possible to obtain simultaneous recordings of most, if not all, relevant circuit neurons, using a combination of intracellular and extracellular recordings. Routine STNS experiments include 4 simultaneous intracellular recordings and 8–12 extracellular nerve recordings. 6. The lar ...
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... 1983-1990). The modi?ed forms of thrombin described in the reports above contain bulky or charged moieties that occupy the active site and also obscure additional regions of the surface of thrombin that bind substrate (Bode. W.. et al.. Embo J (1989) 8: 3467-3475). Some of the chemically modi?ed thr ...
... 1983-1990). The modi?ed forms of thrombin described in the reports above contain bulky or charged moieties that occupy the active site and also obscure additional regions of the surface of thrombin that bind substrate (Bode. W.. et al.. Embo J (1989) 8: 3467-3475). Some of the chemically modi?ed thr ...
1 Cholesterol synthesis, uptake, and regulation I. Structure and
... mediate cholesterol uptake. Since cholesterol in LDL is surrounded by a protein, they made radioactive LDL and looked to see if it bound to the cell surface; it did, with a saturation curve. They then asked what the LDL was binding to. They found a receptor, but to understand how it binds cholestero ...
... mediate cholesterol uptake. Since cholesterol in LDL is surrounded by a protein, they made radioactive LDL and looked to see if it bound to the cell surface; it did, with a saturation curve. They then asked what the LDL was binding to. They found a receptor, but to understand how it binds cholestero ...
Cnidarians and the evolutionary origin of the nervous system Review
... physiological complexity observed in the regionalized nervous system and eye-bearing sensory complex (Rhopalia) of cnidarians, an increasing number of examples indicating the evolutionary convergence in both nervous and sensory systems (Nishikawa 2002) make it difficult to simply compare cnidarian a ...
... physiological complexity observed in the regionalized nervous system and eye-bearing sensory complex (Rhopalia) of cnidarians, an increasing number of examples indicating the evolutionary convergence in both nervous and sensory systems (Nishikawa 2002) make it difficult to simply compare cnidarian a ...
Interactions between frontal cortex and basal ganglia in working
... 1986). The GPi and SNr circuits are functionally analogous (although they have different subcortical targets), so we consider them as one functional entity. Both the frontal cortex and the striatum also receive inputs from various areas of the posterior/sensory cortex. There are also other pathways ...
... 1986). The GPi and SNr circuits are functionally analogous (although they have different subcortical targets), so we consider them as one functional entity. Both the frontal cortex and the striatum also receive inputs from various areas of the posterior/sensory cortex. There are also other pathways ...
Neuronal Control of Mucus Secretion by Leeches: Toward a General
... frequency of the ciliary metachronal waves on each of these gills is controlled by the impulse activity of the branchial nerve, which when cut reduces ciliary activity (Aeillo, 1960) and when stimulated increases the ciliary activity (Aeillo, 1970) of ...
... frequency of the ciliary metachronal waves on each of these gills is controlled by the impulse activity of the branchial nerve, which when cut reduces ciliary activity (Aeillo, 1960) and when stimulated increases the ciliary activity (Aeillo, 1970) of ...
Pain - Viktor`s Notes for the Neurosurgery Resident
... afferent fiber (ephaptic conduction s. “artificial synapses”). 4) denervated spinal neurons become spontaneously active. 5) ↑release of SUBSTANCE P (→ increased transmission at dorsal horn “gates”) – due to: a) increased activity of presynaptic NMDA receptors. b) gene switch → some Aβ fibers (from m ...
... afferent fiber (ephaptic conduction s. “artificial synapses”). 4) denervated spinal neurons become spontaneously active. 5) ↑release of SUBSTANCE P (→ increased transmission at dorsal horn “gates”) – due to: a) increased activity of presynaptic NMDA receptors. b) gene switch → some Aβ fibers (from m ...
Localization of Protein-Protein lnteractions between Subunits of
... Comparison of the known physical properties of phytochrome with kinetic descriptions of phytochrome responses has led to a dimeric model for phytochrome action (VanDerWoude, 1985,1987). In VanDerWoude’s model, cells are thought to preceive mixed dimers in which one subunit is in the Pr form and the ...
... Comparison of the known physical properties of phytochrome with kinetic descriptions of phytochrome responses has led to a dimeric model for phytochrome action (VanDerWoude, 1985,1987). In VanDerWoude’s model, cells are thought to preceive mixed dimers in which one subunit is in the Pr form and the ...
Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
May
29
–
June
1
2011
Quebec
City
Convention
Center
... found that the kinetics of inhibitory postsynaptic currents (IPSCs) were slower in mature synapses (P26‐40) due to the synaptic incorporation of the α5 subunit of the GABAA receptor (a5‐ GABAARs). Moreover, this age‐dependent synaptic expression of a5‐GABAARs was directly associated with the emerg ...
... found that the kinetics of inhibitory postsynaptic currents (IPSCs) were slower in mature synapses (P26‐40) due to the synaptic incorporation of the α5 subunit of the GABAA receptor (a5‐ GABAARs). Moreover, this age‐dependent synaptic expression of a5‐GABAARs was directly associated with the emerg ...
NeuralNets
... highest voltage gated ion channel concentration • Happens if arriving potential > voltage gated channel threshold ...
... highest voltage gated ion channel concentration • Happens if arriving potential > voltage gated channel threshold ...
Localization of Protein-Protein lnteractions between Subunits of
... Comparison of the known physical properties of phytochrome with kinetic descriptions of phytochrome responses has led to a dimeric model for phytochrome action (VanDerWoude, 1985,1987). In VanDerWoude’s model, cells are thought to preceive mixed dimers in which one subunit is in the Pr form and the ...
... Comparison of the known physical properties of phytochrome with kinetic descriptions of phytochrome responses has led to a dimeric model for phytochrome action (VanDerWoude, 1985,1987). In VanDerWoude’s model, cells are thought to preceive mixed dimers in which one subunit is in the Pr form and the ...
cocaine 2008 - addiction education home
... Drug addicts have deficits in frontocortical function and cognition even long after the discontinuation of drug use. It is not clear, however, whether the cognitive deficits are a consequence of drug use, or are present prior to drug use, and thus are a potential predisposing factor for addiction. T ...
... Drug addicts have deficits in frontocortical function and cognition even long after the discontinuation of drug use. It is not clear, however, whether the cognitive deficits are a consequence of drug use, or are present prior to drug use, and thus are a potential predisposing factor for addiction. T ...
Enzymes II: Regulation
... determined may be called primary isoenzymes. The different primary isoenzymes catalyze the same chemical reaction but may differ in their primary structure and kinetic properties. The tissue distribution of isoenzymes imparts distinctive properties and specific patterns of metabolism to organs of th ...
... determined may be called primary isoenzymes. The different primary isoenzymes catalyze the same chemical reaction but may differ in their primary structure and kinetic properties. The tissue distribution of isoenzymes imparts distinctive properties and specific patterns of metabolism to organs of th ...
A dendritic disinhibitory circuit mechanism for pathway
... but otherwise independent of each other. The somatic and dendritic compartments have no spatial extent themselves. This choice of morphology is inspired by previous studies showing that different dendritic branches can integrate their local input independently from one another20. A prominent feature ...
... but otherwise independent of each other. The somatic and dendritic compartments have no spatial extent themselves. This choice of morphology is inspired by previous studies showing that different dendritic branches can integrate their local input independently from one another20. A prominent feature ...
Special senses PPT - Westinghouse College Prep
... such as that caused by an injection or a deep cut • Sensations reach the CNS quickly and often trigger somatic reflexes • Relayed to the primary sensory cortex and receive conscious attention Copyright © 2010 Pearson Education, Inc. ...
... such as that caused by an injection or a deep cut • Sensations reach the CNS quickly and often trigger somatic reflexes • Relayed to the primary sensory cortex and receive conscious attention Copyright © 2010 Pearson Education, Inc. ...
- Warwick WRAP
... Figure 1 Allometric relationships of the brain and body weights of vertebrate animals on a log-log plot. A. Endothermic animals included 678 mammal species [3,16,22,61] (red open circle), 600 bird species [10] (cyan triangle) and 33 insectivore species [16] (purple cross). Ectothermic animals includ ...
... Figure 1 Allometric relationships of the brain and body weights of vertebrate animals on a log-log plot. A. Endothermic animals included 678 mammal species [3,16,22,61] (red open circle), 600 bird species [10] (cyan triangle) and 33 insectivore species [16] (purple cross). Ectothermic animals includ ...
manualE6901
... polymerase gene inserted into the lacZ gene, and thus is under the control of the lac promoter. The strain is deficient in both lon and ompT proteases. ER2566 is supplied as 50% glycerol stock; these cells are not competent. Recommended long term storage (>30 days) is at –70°C. In addition, T7 Expre ...
... polymerase gene inserted into the lacZ gene, and thus is under the control of the lac promoter. The strain is deficient in both lon and ompT proteases. ER2566 is supplied as 50% glycerol stock; these cells are not competent. Recommended long term storage (>30 days) is at –70°C. In addition, T7 Expre ...
Aalborg Universitet Assessment of sensory convergence in the spinal cord
... Melzack, 1999). The difference between the concepts of nociception and the perception of pain must be appreciated. Nociception is in general thought of as the detection of actual or potential tissue damage by transducers in the periphery and the transmission of the information through the nervous sy ...
... Melzack, 1999). The difference between the concepts of nociception and the perception of pain must be appreciated. Nociception is in general thought of as the detection of actual or potential tissue damage by transducers in the periphery and the transmission of the information through the nervous sy ...
Neuropathic ocular pain: an important yet underevaluated feature of
... Dry eye has gained recognition as a public health problem given its prevalence, morbidity, and cost implications. Dry eye can have a variety of symptoms including blurred vision, irritation, and ocular pain. Within dry eyeassociated ocular pain, some patients report transient pain whereas others com ...
... Dry eye has gained recognition as a public health problem given its prevalence, morbidity, and cost implications. Dry eye can have a variety of symptoms including blurred vision, irritation, and ocular pain. Within dry eyeassociated ocular pain, some patients report transient pain whereas others com ...
slides
... measures is called acute – pain is part of the body’s defense system – pain that becomes pathological rather than beneficial is called chronic © Goodheart-Willcox Co., Inc. ...
... measures is called acute – pain is part of the body’s defense system – pain that becomes pathological rather than beneficial is called chronic © Goodheart-Willcox Co., Inc. ...
the brainstem control of saccadic eye movements
... Motor neuron commands. Torsional rotations are produced by contractions of combinations of superior/ inferior rectus and superior/inferior oblique muscle pairs. Consider the activity of motor neurons that innervate one of these muscles, the superior oblique. On the basis of its pulling direction (FI ...
... Motor neuron commands. Torsional rotations are produced by contractions of combinations of superior/ inferior rectus and superior/inferior oblique muscle pairs. Consider the activity of motor neurons that innervate one of these muscles, the superior oblique. On the basis of its pulling direction (FI ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.