Spinal Cord Neural Modeling for Clinical Applications
... research. In addition, he obtained electrophysiological (e.g., EMG) recordings from patients in the clinic, which were used for calibration and validation purposes. The author would like to acknowledge that, were it not for Dr. Arle and Dr. Shils as well as his Brandeis faculty sponsor Dr. Miller, t ...
... research. In addition, he obtained electrophysiological (e.g., EMG) recordings from patients in the clinic, which were used for calibration and validation purposes. The author would like to acknowledge that, were it not for Dr. Arle and Dr. Shils as well as his Brandeis faculty sponsor Dr. Miller, t ...
Gustatory processing is dynamic and distributed Donald B
... cross-correlations. The neuron pair analyzed here crosscorrelated strongly (and negatively) only in the presence of nicotine (orange line) and citric acid (green line). Peaked cross correlations were not found for sucrose (black), NaCl (maroon) or quinine (dark blue). When cross-correlations are tak ...
... cross-correlations. The neuron pair analyzed here crosscorrelated strongly (and negatively) only in the presence of nicotine (orange line) and citric acid (green line). Peaked cross correlations were not found for sucrose (black), NaCl (maroon) or quinine (dark blue). When cross-correlations are tak ...
NIH Public Access
... To allow specific activation of PV+ interneurons, we injected a Cre-inducible adenoassociated virus (AAV) vector containing the ChR2 gene fused in-frame with the coding sequence for enhanced yellow fluorescence protein (EYFP, Supplementary Fig. 1a)8 into V1 of a knock-in mouse line expressing Cre-re ...
... To allow specific activation of PV+ interneurons, we injected a Cre-inducible adenoassociated virus (AAV) vector containing the ChR2 gene fused in-frame with the coding sequence for enhanced yellow fluorescence protein (EYFP, Supplementary Fig. 1a)8 into V1 of a knock-in mouse line expressing Cre-re ...
Goal-Directed Navigation based on Path Integration and Decoding
... do not appear to encode any metric information, such as distances and angles (Spiers and Barry, 2015). The place cell representation by itself is thus not sufficient to be able to navigate between arbitrary locations, because it does not offer any means to calculate the direction of travel from one ...
... do not appear to encode any metric information, such as distances and angles (Spiers and Barry, 2015). The place cell representation by itself is thus not sufficient to be able to navigate between arbitrary locations, because it does not offer any means to calculate the direction of travel from one ...
Somatotopic mapping of natural upper- and lower
... Yet a limitation of the HGM approach applied in previous experimental studies is that, like ESM, it crucially relies on active patient cooperation and compliance over an extended time period. This may be difficult to achieve in infants, small children, and in cognitively impaired individuals, or if e ...
... Yet a limitation of the HGM approach applied in previous experimental studies is that, like ESM, it crucially relies on active patient cooperation and compliance over an extended time period. This may be difficult to achieve in infants, small children, and in cognitively impaired individuals, or if e ...
THE AREA POSTREMA: A POTENTIAL SITE FOR CIRCADIAN REGULATION BY
... ion substitution experiments revealed a PK2-induced Cl- current was responsible for membrane depolarization, while hyperpolarizations were the result of inhibition of an inwardly rectifying non-selective cation current. In contrast to these differential effects on membrane potential, nearly all neur ...
... ion substitution experiments revealed a PK2-induced Cl- current was responsible for membrane depolarization, while hyperpolarizations were the result of inhibition of an inwardly rectifying non-selective cation current. In contrast to these differential effects on membrane potential, nearly all neur ...
Stimulus-Dependent Synchronization of Neuronal Responses in the
... of related responses could be achieved by synchronizing the respective discharges at a time scale of milliseconds, as this would selectively and jointly enhance their saliency. This hypothesis predicts that a given set of neurons should exhibit synchronized discharges more often when responding to a ...
... of related responses could be achieved by synchronizing the respective discharges at a time scale of milliseconds, as this would selectively and jointly enhance their saliency. This hypothesis predicts that a given set of neurons should exhibit synchronized discharges more often when responding to a ...
MULTIPLY CHOICE QUESTIONS ON MEDICAL CHEMISTRY
... D. heterogeneous, two-phases E. heterogeneous, three-phases 1.9. Thermodynamic systems may be divided into following types according to the way of their interaction with the surroundings: А. physical and chemical B. one-, two- and threecomponents C. homogeneous and heterogeneous D. isolated, closed, ...
... D. heterogeneous, two-phases E. heterogeneous, three-phases 1.9. Thermodynamic systems may be divided into following types according to the way of their interaction with the surroundings: А. physical and chemical B. one-, two- and threecomponents C. homogeneous and heterogeneous D. isolated, closed, ...
Stereoscopic Mechanisms in Monkey Visual Cortex: Binocular
... The brain utilizes the signalsfrom the 2 eyes to recover the relative depth of objects.Wheatstone (1838) first demonstrated that a difference, or disparity, in the relative horizontal position of the object’s imagesin the 2 eyescan generatean impression of depth and solidity. Julesz(1960, 1971)later ...
... The brain utilizes the signalsfrom the 2 eyes to recover the relative depth of objects.Wheatstone (1838) first demonstrated that a difference, or disparity, in the relative horizontal position of the object’s imagesin the 2 eyescan generatean impression of depth and solidity. Julesz(1960, 1971)later ...
Time Constants of h Current in Layer II Stellate Cells... along the Dorsal to Ventral Axis of Medial Entorhinal Cortex
... pH adjusted to 7.3 with KOH. The intracellular solution contained 0.1% biocytin for morphological identification and staining of the cells. Cells were visualized on an upright microscope (Axioskop; Carl Zeiss) equipped with a 40⫻ water-immersion objective lenses (Carl Zeiss). With this equipment, th ...
... pH adjusted to 7.3 with KOH. The intracellular solution contained 0.1% biocytin for morphological identification and staining of the cells. Cells were visualized on an upright microscope (Axioskop; Carl Zeiss) equipped with a 40⫻ water-immersion objective lenses (Carl Zeiss). With this equipment, th ...
Neuronal correlates of decision
... Responses of S2 neurons during the comparison period Many neurons in S2 did not respond in a purely sensory manner: their response to stimulus f2 was not simply a function of f2 frequency. Two particularly clear example neurons are shown in Figs. 2 and 3. The trial blocks highlighted by thick black ...
... Responses of S2 neurons during the comparison period Many neurons in S2 did not respond in a purely sensory manner: their response to stimulus f2 was not simply a function of f2 frequency. Two particularly clear example neurons are shown in Figs. 2 and 3. The trial blocks highlighted by thick black ...
Neuronal basis of sequential foraging decisions in a
... then recorded activity of neurons in the dorsal anterior cingulate cortex (dACC) while they performed the task. dACC has been linked to reward outcome monitoring and behavioral adjustment14–16, as well as to signaling reward outcomes and predicting changes in behavior17–24. Notably, ACC dysfunction ...
... then recorded activity of neurons in the dorsal anterior cingulate cortex (dACC) while they performed the task. dACC has been linked to reward outcome monitoring and behavioral adjustment14–16, as well as to signaling reward outcomes and predicting changes in behavior17–24. Notably, ACC dysfunction ...
Circuit Architecture of VTA Dopamine Neurons Revealed by
... To restrict our analysis specifically to VTA-DA and VTA-GABA neurons, we used DAT-Cre mice, in which Cre mimics the expression pattern of the plasma membrane dopamine transporter (Bäckman et al., 2006; Lammel et al., 2015), and GAD2Cre mice, in which Cre mimics the expression of glutamic acid decar ...
... To restrict our analysis specifically to VTA-DA and VTA-GABA neurons, we used DAT-Cre mice, in which Cre mimics the expression pattern of the plasma membrane dopamine transporter (Bäckman et al., 2006; Lammel et al., 2015), and GAD2Cre mice, in which Cre mimics the expression of glutamic acid decar ...
Structural Repair and Functional Recovery Following Cerebral
... of somatostatin and related substances to for many of the regrowing tracts is proact as chemotactic or growth-promoting vided by a connective tissue sheath (capiagents in Melampus CNS regeneration, but tocerebral membrane). It covers the CNS there are many other substances, such as and fans out like ...
... of somatostatin and related substances to for many of the regrowing tracts is proact as chemotactic or growth-promoting vided by a connective tissue sheath (capiagents in Melampus CNS regeneration, but tocerebral membrane). It covers the CNS there are many other substances, such as and fans out like ...
Chapter 08: The Chemical Senses
... — ~300 in mice, 5 in humans — Structurally different from odorant receptors — Ligands are largely unknown Unusual cAMP gated channels are evolutionarily conserved : Used in the visual transduction as well Recent finding suggests both olfactory system and vomeronasal system regulate behavioral outcom ...
... — ~300 in mice, 5 in humans — Structurally different from odorant receptors — Ligands are largely unknown Unusual cAMP gated channels are evolutionarily conserved : Used in the visual transduction as well Recent finding suggests both olfactory system and vomeronasal system regulate behavioral outcom ...
Realizing Biological Spiking Network Models in a Configurable
... NE of the challenges in simulating large neural networks in a parallel, distributed manner is to ensure sufficient communication bandwidth between the computation nodes. Depending on the neural connection densites and the actual spike rates, communication can in fact constitute the major bottleneck l ...
... NE of the challenges in simulating large neural networks in a parallel, distributed manner is to ensure sufficient communication bandwidth between the computation nodes. Depending on the neural connection densites and the actual spike rates, communication can in fact constitute the major bottleneck l ...
CNS*2004 July 18-22, 2004 Baltimore, Maryland
... surrounding areas are included on the following pages along with lists of local activities and restaurants. Registration: Meeting registration will be open in the foyer of the Calvert Ballroom beginning Saturday, July 17th from 5:00-7:00 pm. From Sunday, July 18th to Wednesday, July 21st the Regisra ...
... surrounding areas are included on the following pages along with lists of local activities and restaurants. Registration: Meeting registration will be open in the foyer of the Calvert Ballroom beginning Saturday, July 17th from 5:00-7:00 pm. From Sunday, July 18th to Wednesday, July 21st the Regisra ...
Paper - Wharton Marketing
... then recorded activity of neurons in the dorsal anterior cingulate cortex (dACC) while they performed the task. dACC has been linked to reward outcome monitoring and behavioral adjustment14–16, as well as to signaling reward outcomes and predicting changes in behavior17–24. Notably, ACC dysfunction ...
... then recorded activity of neurons in the dorsal anterior cingulate cortex (dACC) while they performed the task. dACC has been linked to reward outcome monitoring and behavioral adjustment14–16, as well as to signaling reward outcomes and predicting changes in behavior17–24. Notably, ACC dysfunction ...
Heterotopic Transcallosal Projections Are Present throughout the
... the organization of transcallosal connections in different functional regions of the mouse cortex including the primary motor and somatosensory cortices. Such a systematic analysis of inter-hemispheric connectivity is important as defects in those projections—either innate or due to injury—can lead ...
... the organization of transcallosal connections in different functional regions of the mouse cortex including the primary motor and somatosensory cortices. Such a systematic analysis of inter-hemispheric connectivity is important as defects in those projections—either innate or due to injury—can lead ...
Mental Processes -- How the Mind Arises from the Brain Roger Ellman
... ability in non-humans is apparently more limited. Nevertheless, for example, a dog can recognize another dog as a dog even though the dog recognized was never before seen and is of a significantly different breed or appearance. Recognition of universals is not always accurate even though the recogni ...
... ability in non-humans is apparently more limited. Nevertheless, for example, a dog can recognize another dog as a dog even though the dog recognized was never before seen and is of a significantly different breed or appearance. Recognition of universals is not always accurate even though the recogni ...
PDF
... In this Section we consider our simple mathematical model of axon growth (Li et al., 2007; Borisyuk et al., 2008). This model has been studied in detail and has been used here for generation of the connectome model of the whole spinal cord. For the convenience of the reader we include here a brief r ...
... In this Section we consider our simple mathematical model of axon growth (Li et al., 2007; Borisyuk et al., 2008). This model has been studied in detail and has been used here for generation of the connectome model of the whole spinal cord. For the convenience of the reader we include here a brief r ...
Excitatory Cerebellar Nucleocortical Circuit Provides Internal
... MFs of these animals were found predominantly in regions negative for Zebrin II, including the trough of the lobule simplex (Figures 3A–3C). More specifically, we observed that 90.5% (±3.3%), 88.5% (±6.2%), and 93.7% (±2.8%) of the nucleocortical MF originating in the anterior IpN terminated in the ...
... MFs of these animals were found predominantly in regions negative for Zebrin II, including the trough of the lobule simplex (Figures 3A–3C). More specifically, we observed that 90.5% (±3.3%), 88.5% (±6.2%), and 93.7% (±2.8%) of the nucleocortical MF originating in the anterior IpN terminated in the ...
The role of the hypothalamic dorsomedial nucleus in the central
... PrRP immunolabeling was detected in different parts of the hypothalamus. PrRP-ir cell bodies appeared exclusively in the most caudal part of the DMH, while PrRP-ir fibers were present in the dorsal and ventral subdivisions of the DMH, as well as in the arcuate nucleus, the hypothalamic paraventricul ...
... PrRP immunolabeling was detected in different parts of the hypothalamus. PrRP-ir cell bodies appeared exclusively in the most caudal part of the DMH, while PrRP-ir fibers were present in the dorsal and ventral subdivisions of the DMH, as well as in the arcuate nucleus, the hypothalamic paraventricul ...