Separate Representations of Target and Timing Cue Locations in
... stimulus that encodes the target position and also encode the information available from the timing cue. This could pose a challenge to the oculomotor system since the representation of the timing stimulus location in one brain area might be interpreted by downstream neurons as a competing motor pla ...
... stimulus that encodes the target position and also encode the information available from the timing cue. This could pose a challenge to the oculomotor system since the representation of the timing stimulus location in one brain area might be interpreted by downstream neurons as a competing motor pla ...
Cross-modal Circuitry Between Auditory and
... phenomenon will provide insight not only into the incidence of this particular pattern of sensory convergence, but will also contribute to our understanding of the basic principles of multisensory convergence and integration in general. The anterior ectosylvian sulcus (AES) is one of but a few corti ...
... phenomenon will provide insight not only into the incidence of this particular pattern of sensory convergence, but will also contribute to our understanding of the basic principles of multisensory convergence and integration in general. The anterior ectosylvian sulcus (AES) is one of but a few corti ...
Bursting Neurons Signal Input Slope
... Adam Kepecs, Xiao-Jing Wang, and John Lisman Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454 ...
... Adam Kepecs, Xiao-Jing Wang, and John Lisman Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454 ...
Age-Related Uptake of Heavy Metals in Human Spinal Interneurons
... which inhibit the same α-motoneuron, or 1a interneurons which inhibit α-motoneurons supplying antagonist muscles [15]. Any damage to inhibitory interneurons could result in excitotoxicity to α-motoneurons, a mechanism suggested to underlie motoneuron death in ALS/ MND [9]. Neurons containing metal t ...
... which inhibit the same α-motoneuron, or 1a interneurons which inhibit α-motoneurons supplying antagonist muscles [15]. Any damage to inhibitory interneurons could result in excitotoxicity to α-motoneurons, a mechanism suggested to underlie motoneuron death in ALS/ MND [9]. Neurons containing metal t ...
The role of eyes in early face processing: A rapid adaptation study of
... According to the OSH, larger adaptation effects should be found for inverted than upright adaptors regardless of the category. Thus, in response to S2, a decreased activation should be found for inverted compared to upright adaptors, for each adaptor category tested: houses, mouths, eyes, faces, eye ...
... According to the OSH, larger adaptation effects should be found for inverted than upright adaptors regardless of the category. Thus, in response to S2, a decreased activation should be found for inverted compared to upright adaptors, for each adaptor category tested: houses, mouths, eyes, faces, eye ...
Representation of Sounds in Auditory Cortex of Awake
... The brain is the most complex computational device known to Man. Not only does it mediate our orientation in both external (physical) and internal worlds, but—even more astonishingly—the brain enables study of itself. Yet, this amazing device is composed of only a limited set of neurons and their co ...
... The brain is the most complex computational device known to Man. Not only does it mediate our orientation in both external (physical) and internal worlds, but—even more astonishingly—the brain enables study of itself. Yet, this amazing device is composed of only a limited set of neurons and their co ...
Predictions not commands: active inference in the motor system
... system, and illustrate the implicit mechanisms using the classical ‘knee-jerk’ reflex. The active inference view differs from the conventional (computational) views of motor control in conceptual and anatomical terms. Conceptually, under active inference, predictions about proprioceptive input are p ...
... system, and illustrate the implicit mechanisms using the classical ‘knee-jerk’ reflex. The active inference view differs from the conventional (computational) views of motor control in conceptual and anatomical terms. Conceptually, under active inference, predictions about proprioceptive input are p ...
Multiple signalling modalities mediated by dendritic exocytosis of
... (f ) N-methyl-D-aspartate receptors Another major source of free calcium in neurons are the Ca2þ-permeable glutamate N-methyl-D-aspartate receptors (NMDARs). NMDARs are particularly important in MCNs, in which they not only influence overall MCN excitability, but also contribute to the adoption of b ...
... (f ) N-methyl-D-aspartate receptors Another major source of free calcium in neurons are the Ca2þ-permeable glutamate N-methyl-D-aspartate receptors (NMDARs). NMDARs are particularly important in MCNs, in which they not only influence overall MCN excitability, but also contribute to the adoption of b ...
Review. Multiple signaling modalities mediated by dendritic
... (f ) N-methyl-D-aspartate receptors Another major source of free calcium in neurons are the Ca2þ-permeable glutamate N-methyl-D-aspartate receptors (NMDARs). NMDARs are particularly important in MCNs, in which they not only influence overall MCN excitability, but also contribute to the adoption of b ...
... (f ) N-methyl-D-aspartate receptors Another major source of free calcium in neurons are the Ca2þ-permeable glutamate N-methyl-D-aspartate receptors (NMDARs). NMDARs are particularly important in MCNs, in which they not only influence overall MCN excitability, but also contribute to the adoption of b ...
Tang et al - Pro Aid Autisme
... mice, we found that aberrant autophagy and mTOR hyperactivation underlies ASD-like synaptic pathology and correcting autophagy signaling could normalize developmental dendritic spine pruning defects and social behaviors. RESULTS Dendritic Spine Pruning Deficits in ASD Human Brain We measured dendrit ...
... mice, we found that aberrant autophagy and mTOR hyperactivation underlies ASD-like synaptic pathology and correcting autophagy signaling could normalize developmental dendritic spine pruning defects and social behaviors. RESULTS Dendritic Spine Pruning Deficits in ASD Human Brain We measured dendrit ...
Barrel cortex function - Brain Research Institute
... (e.g. Douglas and Martin, 2007; O’Connor et al., 2009). Such an interactive approach will provide mechanistic ideas ‘how’ the cortical machinery might work. However, in order to decide between different mechanistic hypotheses of cortical function the question of ‘what’ is achieved by cortical proces ...
... (e.g. Douglas and Martin, 2007; O’Connor et al., 2009). Such an interactive approach will provide mechanistic ideas ‘how’ the cortical machinery might work. However, in order to decide between different mechanistic hypotheses of cortical function the question of ‘what’ is achieved by cortical proces ...
General Cortical and Special Prefrontal Connections: Principles
... indicator of type for sensory and association cortices. Other architectonic parameters also help describe cortical types quantitatively (Dombrowski et al. 2001). As novel markers are introduced, investigators will be able to use several discriminant features of cortical type to assess with greater a ...
... indicator of type for sensory and association cortices. Other architectonic parameters also help describe cortical types quantitatively (Dombrowski et al. 2001). As novel markers are introduced, investigators will be able to use several discriminant features of cortical type to assess with greater a ...
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in
... which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The neurotrophin brain derived neurotrophic factor (BDNF) is an important growth factor in the CNS. Deficits in transport of this secretory protein could underlie neurodegenera ...
... which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The neurotrophin brain derived neurotrophic factor (BDNF) is an important growth factor in the CNS. Deficits in transport of this secretory protein could underlie neurodegenera ...
The physiological role of orexin/hypocretin neurons in the regulation
... Given that depletion of orexin neurons induces the sleep disorder narcolepsy, the limbic system might also provide important projections to orexin neurons. Narcolepsy patients often suffer from an attack called “cataplexy,” which is characterized by sudden weakening of postural muscle tone. Cataplex ...
... Given that depletion of orexin neurons induces the sleep disorder narcolepsy, the limbic system might also provide important projections to orexin neurons. Narcolepsy patients often suffer from an attack called “cataplexy,” which is characterized by sudden weakening of postural muscle tone. Cataplex ...
electrophysiological and synaptic properties of rat superior and
... guidance during my time in his lab and thereafter; to my committee members, Dr. Arthur J. Weber, Dr. James J. Galligan, and Dr. Hongbing Wang for their individual and collective guidance as well as their technical assistance during this project. I would also like to thank Amit H. Shah for his collab ...
... guidance during my time in his lab and thereafter; to my committee members, Dr. Arthur J. Weber, Dr. James J. Galligan, and Dr. Hongbing Wang for their individual and collective guidance as well as their technical assistance during this project. I would also like to thank Amit H. Shah for his collab ...
Chemosensory Convergence on Primary Olfactory Cortex
... Food perception and preference formation relies on the ability to combine information from both the taste and olfactory systems. Accordingly, psychophysical investigations in humans and behavioral work in animals has shown that the taste system plays an integral role in odor processing. However, the ...
... Food perception and preference formation relies on the ability to combine information from both the taste and olfactory systems. Accordingly, psychophysical investigations in humans and behavioral work in animals has shown that the taste system plays an integral role in odor processing. However, the ...
Homologous Neurons and their Locomotor Functions in Nudibranch
... during the course of evolution than the periphery (Bramble and Wake, 1985; Wainwright and Lauder, 1986; Lauder and Shaffer, 1988; Sanderson, 1988; Goslow et al., 1989; Wainwright, 1989; Wainwright et al., 1989; Kavanau, 1990; Arbas et al., 1991; Edwards and Palka, 1991; Paul, 1991; Katz and Tazaki, ...
... during the course of evolution than the periphery (Bramble and Wake, 1985; Wainwright and Lauder, 1986; Lauder and Shaffer, 1988; Sanderson, 1988; Goslow et al., 1989; Wainwright, 1989; Wainwright et al., 1989; Kavanau, 1990; Arbas et al., 1991; Edwards and Palka, 1991; Paul, 1991; Katz and Tazaki, ...
A Weighted and Directed Interareal Connectivity
... brain for a given injection. The uptake zones of each injection site correspond to a small fraction of the area injected; the volumes of the uptake zone are given in Supplementary Table 2. Injection sites were in general restricted to the cortical gray matter (see Supplementary Fig. 6). However, in ...
... brain for a given injection. The uptake zones of each injection site correspond to a small fraction of the area injected; the volumes of the uptake zone are given in Supplementary Table 2. Injection sites were in general restricted to the cortical gray matter (see Supplementary Fig. 6). However, in ...
neural projections from nucleus accumbens to globus pallidus
... electrophysiological recordings were made from single neurons in these regions to map the location of units that respond to electrical stimulation of the nucleus accumbens. Recordings also were made from neurons in dorsal parts of the GP (GPd) before the microelectrode was lowered to the GP, and the ...
... electrophysiological recordings were made from single neurons in these regions to map the location of units that respond to electrical stimulation of the nucleus accumbens. Recordings also were made from neurons in dorsal parts of the GP (GPd) before the microelectrode was lowered to the GP, and the ...
Primate amygdala neurons evaluate the progress of self
... amygdala single-neuron activity while monkeys performed self-defined choice sequences toward distant rewards. Previously, we reported prospective amygdala signaling of immediate, current-trial choices (Grabenhorst et al., 2012) and forthcoming choice sequences (Hernadi et al., 2015). Although such s ...
... amygdala single-neuron activity while monkeys performed self-defined choice sequences toward distant rewards. Previously, we reported prospective amygdala signaling of immediate, current-trial choices (Grabenhorst et al., 2012) and forthcoming choice sequences (Hernadi et al., 2015). Although such s ...