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Examination of Thyrotropin-Releasing Hormone (TRH)
Examination of Thyrotropin-Releasing Hormone (TRH)

... TH derivatives, contains a relatively large concentration of this enzyme, but D1 is also present in the anterior pituitary, intestine, placenta and thyroid gland [16, 20]. In rats, D1 is also present in the cerebral cortex with relatively low activity, but in humans, D1 is absent from the CNS [21, 2 ...
Neurophysiological involvement in hypervolemic hyponatremia
Neurophysiological involvement in hypervolemic hyponatremia

... of 2% or 5% per hour over 2 h had a biphasic effect on AVP secretion: a short suppression (<60 min) followed by a rebound ...
Development of the brain stem in the rat. V. Thymidine‐radiographic
Development of the brain stem in the rat. V. Thymidine‐radiographic

... the last authors, afferents also come from the ventral nucleus of the lateral geniculate body, the cuneiform nucleus, the periaqueductal gray, and a few other structures. The efferents of t h e parabigeminal nucleus were traced t o the superior colliculus (Kawamura et al., '77; Baleydier and Magnin, ...
Neuromorphic computing
Neuromorphic computing

... Inside a single time step, each neuron is decoupled from the others, thus the simulation of a single time step is an embarrassingly parallel problem. In fact, NEST natively supports MPI and the parallelization of the loop. Moreover, MPI is supported on High Performance Computing platforms! ...
KCNQ/M Channels Control Spike Afterdepolarization and Burst
KCNQ/M Channels Control Spike Afterdepolarization and Burst

... Action potentials were evoked by injecting the neurons with threshold-straddling, brief (4 msec) and long (180 msec) depolarizing current pulses through the recording microelectrode. Linopirdine exerted several effects on active membrane properties (Table 1). The most conspicuous effect was facilita ...
(15 pages pdf)
(15 pages pdf)

... both assays, cocaine influenced behavior in the opposite direction as the DopR mutation, and the effect of cocaine was abolished in DopR mutant flies, supporting the idea that DA inversely regulates these two forms of arousal. Genetic rescue experiments, using Gal4 drivers with restricted CNS expres ...
Axonal Localization of Integrins in the CNS Is Neuronal Type and
Axonal Localization of Integrins in the CNS Is Neuronal Type and

... blocks this growth through inactivation of integrins (Tan et al., 2011). Forced activation of integrins can allow axons to overcome this inhibition (Hu and Strittmatter, 2008; Tan et al. 2011). By increasing the pool of ␣9 integrin in DRG neurons using adeno-associated virus (AAV), a modest increase ...
Disease Modeling Using Embryonic Stem Cells
Disease Modeling Using Embryonic Stem Cells

Frontal Eye Field Sends Delay Activity Related to Movement
Frontal Eye Field Sends Delay Activity Related to Movement

Kisspeptin Signaling Is Required for the Luteinizing Introduction of Males
Kisspeptin Signaling Is Required for the Luteinizing Introduction of Males

... to be in close proximity to kisspeptin neurons [10,11] and pheromones have been shown to activate kisspeptin neurons in mice [12]. The product of the Kiss1 gene, kisspeptin, is one neuropeptide that may provide a link between the olfactory system and GnRH neurons. Kisspeptin signaling is essential f ...
PATHWAYS FOR EMOTION : INTERACTIONS OF PREFRONTAL AND THE RHESUS MONKEY
PATHWAYS FOR EMOTION : INTERACTIONS OF PREFRONTAL AND THE RHESUS MONKEY

... Olmos, 1990). Disruption of these pathways seriously a¡ects emotional expression, as exempli¢ed by the inability of patients with orbitofrontal lesions to respond autonomically in emotional situations (Damasio et al., 1990; for review see Kling and Steklis, 1976). Even though such patients have inta ...
PDF
PDF

Outputs of Radula Mechanoafferent Neurons in Aplysia are
Outputs of Radula Mechanoafferent Neurons in Aplysia are

... generate behavior. A form of sensory modulation was investigated in the Aplysia feeding system at the level of a radula mechanoafferent neuron (B21) that provides chemical synaptic input to a group of motor neurons (B8a/b, B15) that control closure and retraction movements of the radula, a food gras ...
High-frequency stimulation in Parkinson`s disease: more
High-frequency stimulation in Parkinson`s disease: more

A transcription factor network controls cell migration
A transcription factor network controls cell migration

... The relative numbers of neuronal cell types produced during pineal complex development are very consistent across embryos, suggesting the existence of a robust molecular mechanism that governs cell specification in the pineal complex. Indeed, within the pineal organ, BMP and Notch activities regulat ...
Input-specific control of reward and aversion in the ventral tegmental
Input-specific control of reward and aversion in the ventral tegmental

... differentially modulate such circuits. Here we show that, because of differences in synaptic connectivity, activation of inputs to the VTA from the laterodorsal tegmentum and the lateral habenula elicit reward and aversion in mice, respectively. Laterodorsal tegmentum neurons preferentially synapse ...
The Orbitofrontal Cortex and Reward
The Orbitofrontal Cortex and Reward

... reinforcement contingencies change. The monkeys may respond when responses are inappropriate, e.g. no longer rewarded, or may respond to a non-rewarded stimulus. For example, monkeys with orbitofrontal damage are impaired on go/no-go task performance, in that they go on the no-go trials (Iversen and ...
Postnatal Development of the Corticospinal Tract in the Reeler Mouse
Postnatal Development of the Corticospinal Tract in the Reeler Mouse

... Corticospinal tract (CST) neurons are located in layer V of the motor cortex, and send their axons to the spinal motoneurons, directly (5, 23) or indirectly (2, 35). The CST forms the longest axonal projection in the mammalian central nervous system (CNS). The development of CST axons is the latest ...
Tuning Curve Shift by Attention Modulation in Cortical Neurons: a
Tuning Curve Shift by Attention Modulation in Cortical Neurons: a

Coordinate Roles for LIM Homeobox Genes in Directing the
Coordinate Roles for LIM Homeobox Genes in Directing the

... neural tube that lie in register with the limb fields (Hamburger, 1977; Ensini et al., 1998). LMC neurons initially project their axons along a common path, but at the base of the limb, the motor nerve bifurcates to form distinct dorsal and ventral branches (Figure 1A). The decision of motor axons t ...
Altered fear learning across development in both mouse and human
Altered fear learning across development in both mouse and human

... COGNITIVE SCIENCES ...
Ectopic Expression of the Neuropeptide Pigment
Ectopic Expression of the Neuropeptide Pigment

Temporal modulation of the dynamics of neuronal networks with
Temporal modulation of the dynamics of neuronal networks with

... ring rates were not robustly associated with dierent behavioral responses, while deviations from a neuron-specic prototypical spike train predicted slower responses of the monkeys. These deviations could be due to increased or decreased spike count, as well as to jitters in spike times. Our resul ...
Article - Leslie Vosshall - The Rockefeller University
Article - Leslie Vosshall - The Rockefeller University

L8-Physiology of Sleep and EEG 2013
L8-Physiology of Sleep and EEG 2013

... Spindles are groups of waves that occur during many sleep stages but especially in stage 2.  They have frequencies in the upper levels of alpha or lower levels of beta.  Lasting for a second or less, they increase in amplitude initially and then decrease slowly. The waveform resembles a spindle.  ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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