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... type of preparation simply consisted of the isolated buccal and cerebral ganglia. This type of preparation was used in experiments in which single cycles of ingestive motor programs were elicited by stimulation of the command-like neuron cerebral buccal interneuron 2 (CBI-2) (Rosen et al., 1991; Chu ...
Dorsal Anterior Cingulate Cortex: A Bottom-Up View
Dorsal Anterior Cingulate Cortex: A Bottom-Up View

Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine
Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine

... (McFarland et al., 2003; McLaughlin and See, 2003; Sun and Rebec, 2003; Stefanik and Kalivas, 2013; Stefanik et al., 2013); however, recent evidence indicates that only subpopulations of neurons within brain structures drive drug-seeking behaviors (Bossert et al., 2011; Cruz et al., 2013, 2014; Moor ...
A role for subplate neurons in the patterning of
A role for subplate neurons in the patterning of

... were added to the kainic acid solution (at a ratio of 1:9, microspheres: kainic acid) to mark the injection site. (The microspheres form a stable nontoxic and long-lasting deposit that can be viewed weeks to months later, and they are also transported retrogradely by the LGN neurons.) For animals at ...
Implication of novel neurotransmitter systems in the regulation of
Implication of novel neurotransmitter systems in the regulation of

... which release their neurohormone content into the portal circulation of the hypophysis in a pulsatile manner. The episodic hormone release from the GnRH axon terminals results in a rhythmic discharge of the two gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), by the go ...
Distinct Roles for Somatically and Dendritically Synthesized Brain
Distinct Roles for Somatically and Dendritically Synthesized Brain

... (Harris, 1999). Dendritic spines are highly dynamic structures that undergo changes in size, shape, and number during development, as well as in response to physiological stimuli such as learning (Holtmaat and Svoboda, 2009; Yoshihara et al., 2009). Alterations in spine shape and density are associa ...
Binary neurons and networks
Binary neurons and networks

... Not compatible with biology ...
Dynamics of spontaneous activity in the cerebral cortex across brain states
Dynamics of spontaneous activity in the cerebral cortex across brain states

... TDX (www.tdx.cat) service and by the UB Digital Repository (diposit.ub.edu) has been authorized by the titular of the intellectual property rights only for private uses placed in investigation and teaching activities. Reproduction with lucrative aims is not authorized nor its spreading and availabil ...
Table of Contents
Table of Contents

... 3. GABA neurons in nematodes To identify the GABA-containing cells in C. elegans, wild-type animals were stained with antibodies against the neurotransmitter. Antibody staining revealed that 26 of the 302 neurons present in C. elegans express the neurotransmitter GABA (Figure 2A). These 26 GABA neur ...
Motif distribution, dynamical properties, and computational
Motif distribution, dynamical properties, and computational

... the computational properties of microcircuit templates we carried out computer simulations of detailed cortical microcircuit models consisting of 560 Hodgkin–Huxley type point neurons and synaptic connections with stereotypical dynamic properties (such as paired pulse depression and paired pulse fac ...
Essential Roles for GSK-3s and GSK-3
Essential Roles for GSK-3s and GSK-3

... GSK-3 activity led to a defect in axon development in hippocampal neurons. However, Wnts also reportedly stimulate the extension of postcrossing commissural axons (Lyuksyutova et al., 2003). Further, two recent studies showed that formation of multiple long axons was induced in hippocampal cultures ...
Functional Microarchitecture of Cat Primary Visual Cortex
Functional Microarchitecture of Cat Primary Visual Cortex

... more clustered than would be expected from a random distribution. However, preferred phase, direction selectivity, relative modulation (F1/DC), and spatial frequency preference and tuning width showed no such clustering. By investigating the temporal patterns of neighbouring neurons in response to m ...
University of Groningen Gustatory neural processing in the
University of Groningen Gustatory neural processing in the

... range of taste sensation 106. Moreover, molecules that elicit similar verbal reports of taste from humans or neural activity in gustatory afferent nerves often bear little chemical relation to one another. For example, many mono- and disaccharides taste sweet to humans. Not all sugars however, taste ...
After all, it`s still replication: A reply to Jacob on simulation and mirror
After all, it`s still replication: A reply to Jacob on simulation and mirror

Spike-based Winner-Take-All Computation in a Multi
Spike-based Winner-Take-All Computation in a Multi

... its performance and describing its implementation in a large-scale multi-chip vision system. The winner-take-all is a neuronal network that amplifies the strongest set of inputs and suppresses output from the others. In various neuroscience models, this function is used to make a selection out of a ...
Apparent Loss and Hypertrophy of Interneurons in a Mouse Model
Apparent Loss and Hypertrophy of Interneurons in a Mouse Model

... other tissues (Koenig, 1964; Haltia et al., 1973; Dyken, 1988; Goebel, 1995). Ultrastructurally, these electron-dense accumulations exhibit granular, curvilinear, or fingerprint-like appearances that are characteristic for each form of NCL (Santavuori, 1988; Goebel, 1995, 1997). Biochemical studies ...
the effects of microstimulation and microlesions in the ventral and
the effects of microstimulation and microlesions in the ventral and

... response to stimulation was observed in a single trial in any of the recorded signals, the response was examined more closely by using a laboratory satellite computer to determine the latency and duration of the response to individual stimulus pulses. Analog signals were converted to 12-bit digital ...
Neuropathological Characteristics of Brachial Plexus Avulsion Injury
Neuropathological Characteristics of Brachial Plexus Avulsion Injury

... N2O and 30% O2) via snout mask. Endotracheal intubation was performed using a 4.5-mm endotracheal tube and maintenance of anesthesia achieved via inhaled isofluorane (2%, 70% N2O and 30% O2). Intravenous access was obtained via cannulation of the ear vein, and normal saline (40 cc/hour) was administ ...
Structure and Function of the Brain Serotonin System
Structure and Function of the Brain Serotonin System

melanogaster
melanogaster

... the ight-induced visual boost. This work provides the rst evidence that endogenous release of octopamine is involved in state-dependent modulation of visual interneurons in ies. Further, I investigated the role of a single pair of octopamine neurons that project to the optic lobes, and found no e ...
The Relation between Dendritic Geometry
The Relation between Dendritic Geometry

... software (MicroBright-Field, Colchester, VT) using an Olympus Optical (Hamburg, Germany) BX50 microscope at a final magnification of 10003 (using a 1003, 1.25 NA objective). The reconstructions provided the basis for the quantitative morphological analysis (see below). The soma was reconstructed by dr ...
Background - Harvard University
Background - Harvard University

... of all the studies done. We focus on the activity of single neurons studied by neurophysiological techniques in behaving animals, in particular monkeys, and emphasize the formative role of behavioral theories, such as animal learning theory and microeconomic utility theory, on the understanding of t ...
Dopaminergic control of the globus pallidus and its impact
Dopaminergic control of the globus pallidus and its impact

Neural correlates of stimulus–response and response–outcome
Neural correlates of stimulus–response and response–outcome

... and movements should be represented in dorsomedial but not dorsolateral striatum, whereas associations between cues and responses, independent of reward value, should be represented in neural activity in dorsolateral but not dorsomedial striatum. Additionally, neural activity in dorsomedial striatum ...
Response Properties of Neighboring Neurons in the
Response Properties of Neighboring Neurons in the

... auditory system to characterize single-unit responses. In particular, we looked at the frequency selectivity as defined by best frequency and the width of the frequency tuning; we looked at both the pure tone threshold and level-dependency; we characterized the temporal discharge patterns elicited b ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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