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Reduced Levels of Acetylcholine Receptor Expression in Chick
Reduced Levels of Acetylcholine Receptor Expression in Chick

... sections from operated and control embryos during the labeling procedures, each slide contained three or four serial sections from both input-deprived and control ganglia. To establish the specificity of the labeling, a few slides from each experiment were processed as described above except that mA ...
Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy
Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy

... showing sensory fibers in the ventral horn (B1), the location of VGluT1+ synapses (B2), and their colocalization in the merged image (B3). (C1 and C2) Transverse section from an SMA spinal cord as in (A1) and (A2). (D1–D3) Labeled sensory fibers (D1) and VGluT1+ synapses (D2) in the ventral horn (D3 ...
Behavioral Detectability of Single-Cell Stimulation in the Ventral
Behavioral Detectability of Single-Cell Stimulation in the Ventral

Chapter 2
Chapter 2

... microscopic level nor have the local axons from IC GABAergic neurons (see Section 4.2). Although the inputs to ICC have been identified at the electron microscopic level, their synaptic role in processing auditory information remains an area of intense interest. For example, it is unclear whether th ...
Maruska & Tricas 2011
Maruska & Tricas 2011

... elevate circulating androgen levels in the green treefrog Hyla cinerea (Burmeister and Wilczynski, 2000), and acoustic stimulation with conspecific sounds triggers luteinizing hormone release in some birds (Cheng et al., 1998; Maney et al., 2007). While these studies are consistent with the hypothesi ...
Sound processing by local neural populations in the
Sound processing by local neural populations in the

... numbers of synaptically connected neurons. The combination of the computation individual neurons perform on their input with the pattern of flow of activation between the neurons create population activation patterns which underlie perception and are largely unknown. However, studies have shown that ...
The occipitoparietal pathway of the macaque monkey: comparison
The occipitoparietal pathway of the macaque monkey: comparison

... al., 1990; Sousa et al., 1991; Rosa et al., 1993). Projections that originate mainly in the supragranular layers and terminate around layer IV are referred to as ‘feedforward’, and projections that originate mainly from infragranular layers and terminate outside layer IV are referred to as ‘feedback ...
In VivoCalcium Imaging Reveals Functional Rewiring of Single
In VivoCalcium Imaging Reveals Functional Rewiring of Single

... (Stosiek et al., 2003; Garaschuk et al., 2006). Wherever possible, microinjections of OGB-1 were made into both cFL- and cHL-responsive regions, as identified by the poststroke IOS response map. Subsequent to OGB-1 AM injection, the cortex was incubated with sulforhodamine 101 (SR101; Sigma-Aldrich) ...
neurophysics.ucsd.edu
neurophysics.ucsd.edu

... used for touch [5,6]. In humans and some other mammalian species, specialized orofacial movements produce vocalizations or speech. These actions, which are central to mammalian life, must be coordinated with a high degree of precision to prevent blockages of the airway and other maladaptive interact ...
Kazumi TAKAHASHI†*, Jian-Sheng LIN† and Kazuya - HAL
Kazumi TAKAHASHI†*, Jian-Sheng LIN† and Kazuya - HAL

... The preoptic area (POA) of the anterior hypothalamus and the adjacent basal forebrain (BFB) play an important role in the regulation of homeostatic and cognitive processes, including blood pressure, thermoregulation, sexual behavior, attention, learning, and cortical activity (Boulant and Dean, 1986 ...
Wang et al 2photon calcium imaging of odor in fly brain cell 2003
Wang et al 2photon calcium imaging of odor in fly brain cell 2003

... response to odors are revealed by these initial experiments. Different odors elicit different patterns of glomerular activation and these patterns are conserved among different animals. At odor concentrations likely to be encountered in nature, the map is sparse and glomeruli are narrowly tuned. The ...
Total Wiring Length Minimization of C. elegans Neural
Total Wiring Length Minimization of C. elegans Neural

... using materials from [1] and new electron micrographs reported an updated set of data on electrical and chemical connections of the hermaphrodite worm. Although [3] was published in 2011, this updated connectivity dataset had been obtained before, and employed for example, in [4]. This refined datas ...
Saccade Target Selection in the Superior - Smith
Saccade Target Selection in the Superior - Smith

... and Wurtz (1995) and Basso and Wurtz (1998). The final category is the movement neuron, which discharges a burst of activity tightly linked to saccade execution but does not have significant visual or delay activity (Fig. 1E). ...
For Peer Review - diss.fu
For Peer Review - diss.fu

... MnR: 7.8 mm posterior to bregma, 0.8 from the midline, and 7.8 mm ventral to the dura (-6°). Hemisphere for injections into VTA was randomized prior to each experiment. The retrograde tracer Fluorogold (FG; 2-hydroxy-4,4-diamino-stilbene, 1% in 0.1 M cacodylate buffer, pH 7.4; Fluorochrome, Denver, ...
Central mechanisms of osmosensation and systemic osmoregulation
Central mechanisms of osmosensation and systemic osmoregulation

... 15 minutes56. Osmoreceptors in these areas can therefore detect the osmotic strength of ingested materials and, through afferent connections to the CNS (FIG. 3), induce anticipatory responses that might buffer the potential impact of ingestion-related osmotic perturbations61. Indeed, water intake ca ...
NK1 receptor-expressing spinoparabrachial neurons trigger diffuse
NK1 receptor-expressing spinoparabrachial neurons trigger diffuse

... feature of DNIC is that they are subserved by a loop that involves supraspinal structures that have not yet been identified. Using behavioral, in vivo extracellular electrophysiological and anatomical approaches, we studied the neuronal network underlying DNIC. Using a new behavioral model of DNIC, i ...
Simultaneous Two-Photon Calcium Imaging of Entire Cortical
Simultaneous Two-Photon Calcium Imaging of Entire Cortical

... Figure 1. Chronic functional imaging across cortical layers using a microprism. A, Illustration of laser beam path through a prism implanted into neocortex. The reflective hypotenuse of the prism converts the horizontal imaging plane into a vertical plane. B, Flowchart of surgical procedures. Surger ...
NIH Public Access
NIH Public Access

... Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is publi ...
Antennal Mechanosensory Neurons Mediate Wing Motor Reflexes
Antennal Mechanosensory Neurons Mediate Wing Motor Reflexes

... Presentations of visual stimuli. We used a previously described light emitting diode (LED) display to present visual stimuli to the flies (Reiser and Dickinson, 2008). To separate the wavelength of the light emitted by the LED from the GCaMP3 fluorescence, we used blue LEDs (470 nm peak wavelength; ...
PDF+Links
PDF+Links

... that age-related pathological brain dysfunction might be ameliorated by treatment with neurotrophic factor. Most of earlier studies usually estimated degenerative or atrophic changes in morphology of the cholinergic neurons. However, recently attention has been focused on the idea that, during norma ...
SOM
SOM

... • Neural networks for unsupervised learning attempt to discover special patterns from available data without using external help (i.e. RISK FUNCTION). – There is no information about the desired class (or output ) d of an example x. So only x is given. – Self Organising Maps (SOM) are neural network ...
Horizontal Synaptic Connections in Monkey Prefrontal Cortex: An In
Horizontal Synaptic Connections in Monkey Prefrontal Cortex: An In

... projections were well preserved in PFC slices cut in the coronal plane. Postsynaptic currents were evoked by low-intensity electrical extracellular stimulation applied successively to 20–30 discrete sites located up to 2200 µm lateral to the recorded cell. Several criteria were applied to discrimina ...
Nogo Receptor mRNA Expression in Intact and Regenerating CNS
Nogo Receptor mRNA Expression in Intact and Regenerating CNS

... and Aguayo, 1982; Vaudano et al., 1993, 1998; Chaisuksunt et al., 2000). It is not clear why CNS neurons show such variations in regenerative capacity (Anderson and Lieberman, 1999) but differential sensitivity to growthinhibitory molecules is one possible explanation. The suggestion that CNS myelin ...
Local functions for FMRP in axon growth cone motility and activity
Local functions for FMRP in axon growth cone motility and activity

... (Fig. 3A), as done by others (Prange and Murphy, 2001), since it is difficult during this stage of development in culture (2 weeks) to unequivocally distinguish spines from filopodium based solely on morphologic criteria. This is because filopodia are abundant and many spines have an ambiguous morph ...
Comparative neuronal morphology of the
Comparative neuronal morphology of the

... Although there are many representative freehand and camera lucida drawings of cerebellar cortex neurons (Ramón y Cajal, 1909, 1911; Chan-Palay and Palay, 1970, 1972; Palay and ChanPalay, 1974; Braak and Braak, 1983; Bishop, 1993; Lainé and Axelrad, 1996), very few cerebellar neurons have been digita ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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