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Full Text  - Cerebral Cortex
Full Text - Cerebral Cortex

... neurons have also been shown to respond to reward, reinforcement and error (Niki and Watanabe, 1979; Watanabe, 1989). Because the OFC is more related to motivational operations than the LPFC (Fuster, 1997), and delay-related activity changes of primate OFC neurons have not been examined sufficiently ...
The Role of Histamine H1 , H2 and H3 Receptors on Enteric
The Role of Histamine H1 , H2 and H3 Receptors on Enteric

Synchronous Oscillatory Neural Ensembles for Rules in the
Synchronous Oscillatory Neural Ensembles for Rules in the

Cortical areas are linked through pathways which originate and
Cortical areas are linked through pathways which originate and

... is the pattern of connection between eulaminate areas with different laminar organization? What is the relative distribution of projection neurons or axonal terminals in different layers when structurally distinct cortices, in general, are connected? The present study addresses these questions by fo ...
Laminar  Selectivity of  the  Cholinergic Suppression of  Synaptic
Laminar Selectivity of the Cholinergic Suppression of Synaptic

... matrix in s. rad (R,,) started with random initial connection strengths with a mean of 0.157, giving an average initial input of 6aO.157 = 0.942 for patterns in which six neurons in region CA3 had output 1 .O.Synapses of R,, could not be weaker than 0.1 or stronger than 0.5. This difference in stren ...
The habenular nuclei - Philosophical Transactions of the Royal
The habenular nuclei - Philosophical Transactions of the Royal

Query Performance Problem Determination with Knowledge Base in
Query Performance Problem Determination with Knowledge Base in

... At the enterprise level, major commercial state-of-the-art relational database systems such as IBM DB2®, Oracle®, and Microsoft® SQL Server® are deployed in environments where finding all available optimizations and performance tuning strategies becomes necessary to maintain the usability of the dat ...
Electronic Realization of Human Brain`s Neo
Electronic Realization of Human Brain`s Neo

... to get close to VLSI mimicry of the brain power efficiency. The brain consisting of 1010 neurons with 1014 neural connections is a very power efficient system that is still the most complex system to date [16]. Comparison of hardware/software implementation and software simulations shows how faraway ...
Matching tutor to student: rules and mechanisms for
Matching tutor to student: rules and mechanisms for

... We considered a model for information transfer that is composed of three sub-circuits: a conductor, a student, and a tutor (see Fig. 1B). The conductor provides input to the student in the form of temporally precise patterns. The goal of learning is for the student to convert this input to a predefi ...
Synapse formation in developing neural circuits.
Synapse formation in developing neural circuits.

... than NMJs, in closed apposition to one another and packed at very high densities. This made their visualization with the methods used during nineteenth century downright impossible and triggered the postulation of the ‘‘reticular theory’’: the idea that the nervous system lacked functional separatio ...
Mechanisms Underlying the Cardioinhibitory and Pressor
Mechanisms Underlying the Cardioinhibitory and Pressor

Citation As Published Publisher Version Accessed
Citation As Published Publisher Version Accessed

Synaptic Regulation of Action Potential Timing in
Synaptic Regulation of Action Potential Timing in

... yielding tip resistances of 5– 8 MV. Series resistance (15–30 MV) was monitored throughout the recording, and neurons exhibiting .25% change were rejected. Voltage errors attributable to series resistance and the liquid junction potential were subtracted off-line. In some instances in which the reve ...
Corticomuscular Contributions to the Control of Rhythmic Movement
Corticomuscular Contributions to the Control of Rhythmic Movement

... The inherent simplicity of human locomotion is deceiving in nature and its complexity becomes apparent when we observe children as they learn to walk or patients suffering from neuromuscular disorders. Human movement requires inputs from supraspinal and spinal centers as well as sensory afferent fee ...
D2 receptor overexpression in the striatum leads to a deficit in
D2 receptor overexpression in the striatum leads to a deficit in

... SKF-81297 on the evoked IPSC and EPSC trains in both transgenic and control mice. SKF-81297 is a highly D1-selective agonist, which has a Ki for the D1 receptor of ∼2 nM but has a Ki for the D2R of ∼1,000 nM (24). We and others recently reported that SKF-81297 at a concentration of 1 μM significantly ...
Genetic Diversity of Principal Neurons in the Hippocampus
Genetic Diversity of Principal Neurons in the Hippocampus

LINKING PROPOSITIONS*
LINKING PROPOSITIONS*

Resonance Effect for Neural Spike Time Reliability
Resonance Effect for Neural Spike Time Reliability

... relative to the intensity of the fluctuating input currents. In interpreting these results, an important consideration is the magnitude of the fluctuations in the input relative to the current necessary to cause neuronal spiking. It is not difficult to appreciate that spike timing will be reliable w ...
Measurement of variability dynamics in cortical spike trains
Measurement of variability dynamics in cortical spike trains

... performed with the help of Mathematica (Wolfram Research, Inc.). We provide documented Matlab code for some of the methods described below within the framework of the FIND toolbox (Meier et al., 2007; http://find.bccn.uni-freiburg.de). 2.1.3. Operational time and rate modulation Neurons observed in ...
Electrical stimulation of neural tissue to evoke behavioral responses
Electrical stimulation of neural tissue to evoke behavioral responses

... estimate how far from the electrode tip current activates neural tissue mediating behaviors such as eating (Olds, 1958), self-stimulation (Wise, 1972; Fouriezos and Wise, 1984; Milner and Laferriere, 1986), and circling behavior (Yeomans et al., 1984, 1986). The method used by Fouriezos and Wise (19 ...
The Fine Structure of Slow-Wave Sleep Oscillations: from Single
The Fine Structure of Slow-Wave Sleep Oscillations: from Single

The Diversity of Cortical Interneurons
The Diversity of Cortical Interneurons

... transfer of information between different areas, whereas interneurons primarily contribute to local neural assemblies to modulate the flow of information there. Pyramidal fall into over a few classes, regardless of the enormous amount of information they have to deal with. The functional repertoire ...
HB-GAM (pleiotrophin) reverses inhibition of neural
HB-GAM (pleiotrophin) reverses inhibition of neural

... HB-GAM alone, added in solution at the time of cell plating on uncoated tissue culture plastic, did not promote neurite outgrowth, but rather displayed some inhibitory effect (Fig. 1c). Conversely, when HB-GAM was added in solution with the cells on aggrecan-coated wells, a prominent neurite outgrow ...
the evolution of body and brain, and of sensory
the evolution of body and brain, and of sensory

... traits that herald human characteristics. Among these are, relative to basal mammals and prosimians, a large skull, forward looking eyes and reduced muzzle (Fig. 6-2), and long arms and fingers. These physical traits are coupled with several human-like behavioral characteristics, including increased ...
Somatosensory System Organization and Texture Sensation in Rats
Somatosensory System Organization and Texture Sensation in Rats

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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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