The neurophysiological correlates of motor tics following focal
... The cortico-basal ganglia pathway is involved in normal motor control and implicated in multiple movement disorders. Brief repetitive muscle contractions known as motor tics are a common symptom in several basal ganglia related motor disorders. We used focal micro-injections of the GABA-A antagonist ...
... The cortico-basal ganglia pathway is involved in normal motor control and implicated in multiple movement disorders. Brief repetitive muscle contractions known as motor tics are a common symptom in several basal ganglia related motor disorders. We used focal micro-injections of the GABA-A antagonist ...
stereological estimates of dopaminergic, gabaergic and
... Total estimates of the number of GABAergic and dopaminergic neurons were obtained from four brains processed for GAD in situ hybridization and TH immunohistochemistry. Estimates of glutamatergic neurons were obtained from a further four brains processed for VGluT2 in situ hybridization and TH immuno ...
... Total estimates of the number of GABAergic and dopaminergic neurons were obtained from four brains processed for GAD in situ hybridization and TH immunohistochemistry. Estimates of glutamatergic neurons were obtained from a further four brains processed for VGluT2 in situ hybridization and TH immuno ...
The Role of Voltage Gated Sodium Channels 1
... expression was demonstrated by the discovery of C fibres that are normally 'silent'. These fibres become activated by the inflammatory soup released in response to injury, and behave just as all other C fibre nociceptors, except they have a ninety percent expression of Nav 1.9 (Amir et al 2006). All ...
... expression was demonstrated by the discovery of C fibres that are normally 'silent'. These fibres become activated by the inflammatory soup released in response to injury, and behave just as all other C fibre nociceptors, except they have a ninety percent expression of Nav 1.9 (Amir et al 2006). All ...
BOOK 1: Nervous system anatomy and function
... One type of monitoring approach is to use a microelectrode -- a small, microscopic probe typically made of glass or metal -- to record the number of action potentials a dopamine neuron generates. This technique is called electrophysiology or monitoring the “electrical functioning” of the neuron. The ...
... One type of monitoring approach is to use a microelectrode -- a small, microscopic probe typically made of glass or metal -- to record the number of action potentials a dopamine neuron generates. This technique is called electrophysiology or monitoring the “electrical functioning” of the neuron. The ...
Response Properties of Neighboring Neurons in the
... the overall cell density could illuminate many questions about the processing and organization of physiological information in different systems. Recording the multi-unit activity of a small number of cells provides a reliable method for recording from multiple neurons that are relatively close toge ...
... the overall cell density could illuminate many questions about the processing and organization of physiological information in different systems. Recording the multi-unit activity of a small number of cells provides a reliable method for recording from multiple neurons that are relatively close toge ...
Read as PDF
... that receives chemical synaptic input. Previously we demonstrated that the somatic membrane potential determines spike propagation within B21. Namely, B21 must be centrally depolarized if spikes are to propagate to an output process. We now demonstrate that this will occur with central depolarizatio ...
... that receives chemical synaptic input. Previously we demonstrated that the somatic membrane potential determines spike propagation within B21. Namely, B21 must be centrally depolarized if spikes are to propagate to an output process. We now demonstrate that this will occur with central depolarizatio ...
Turtle Dorsal Cortex Pyramidal Neurons Comprise Two Distinct Cell
... hypothesis that cellular individuality represents a smaller computational role within the context of the larger network. These competing hypotheses raise the important question to what extent the computational function of a neuron is determined by its individual type or by its circuit connections. W ...
... hypothesis that cellular individuality represents a smaller computational role within the context of the larger network. These competing hypotheses raise the important question to what extent the computational function of a neuron is determined by its individual type or by its circuit connections. W ...
Document
... Membrane proteins carry out func ons such as nutrient uptake, ATP synthesis or transmembrane signal transduc on. An increasing number of reports indicate that cellular processes are underpinned by regulated interac ons between these proteins. Consequently, func onal studies of these networks at a mo ...
... Membrane proteins carry out func ons such as nutrient uptake, ATP synthesis or transmembrane signal transduc on. An increasing number of reports indicate that cellular processes are underpinned by regulated interac ons between these proteins. Consequently, func onal studies of these networks at a mo ...
Representational Capacity of Face Coding in Monkeys
... the population of coding neurons. If each stimulus is represented by the firing of a single neuron or "grandmother cell," the number of stimuli that can be represented is proportional to the number of neurons. If the information about each stimulus is distributed across the full population, the numb ...
... the population of coding neurons. If each stimulus is represented by the firing of a single neuron or "grandmother cell," the number of stimuli that can be represented is proportional to the number of neurons. If the information about each stimulus is distributed across the full population, the numb ...
ICDVRAT2006_S09_N01_Miranda
... effectively, they often do not allow as much control for those with severe physical disabilities. At present, access music tutors use gesture devices and adapted accessible technology to make this possible, which achieve excellent results; although for people with severe physical disabilities, havin ...
... effectively, they often do not allow as much control for those with severe physical disabilities. At present, access music tutors use gesture devices and adapted accessible technology to make this possible, which achieve excellent results; although for people with severe physical disabilities, havin ...
The columnar organization of the neocortex
... neocortex. Columnar defining factors in homotypical areas are generated, in part, within the cortex itself. The set of all modules composing such an entity may be fractionated into different modular subsets by different extrinsic connections. Linkages between them and subsets in other large entities ...
... neocortex. Columnar defining factors in homotypical areas are generated, in part, within the cortex itself. The set of all modules composing such an entity may be fractionated into different modular subsets by different extrinsic connections. Linkages between them and subsets in other large entities ...
Postnatal characterization of cells in the accessory olfactory bulb of
... of the layering of AOB/MOB and second, the determination of cellular phenotypes in the AOB in a time window corresponding to the early postnatal development. Moreover, since reelin (Reln) deficiency has been related to olfactory learning deficits, we analyzed reeler mice. First, we compared the laye ...
... of the layering of AOB/MOB and second, the determination of cellular phenotypes in the AOB in a time window corresponding to the early postnatal development. Moreover, since reelin (Reln) deficiency has been related to olfactory learning deficits, we analyzed reeler mice. First, we compared the laye ...
Morphology and Physiology of the Cerebellar Vestibulolateral Lobe
... All experiments that included electrical stimulation were carried out in anesthetized goldfish that received pentobarbital sodium (20 –30 mg/kg) and gallamine triethiodide (Flaxedil; 1–2 mg/kg). Goldfish were wrapped in protective cotton gauze, placed in a white acrylic aquarium (27 cm diameter) fil ...
... All experiments that included electrical stimulation were carried out in anesthetized goldfish that received pentobarbital sodium (20 –30 mg/kg) and gallamine triethiodide (Flaxedil; 1–2 mg/kg). Goldfish were wrapped in protective cotton gauze, placed in a white acrylic aquarium (27 cm diameter) fil ...
J.H. Meijer, S. Michel, M.J. Vansteensel
... extracellular recording electrodes, for instance low impedance metal electrodes. Such extracellular recordings can be performed in brain slices for extended periods of time. The electrical signals of several microvolts are amplified and counted when above a certain threshold (signal to noise level 3: ...
... extracellular recording electrodes, for instance low impedance metal electrodes. Such extracellular recordings can be performed in brain slices for extended periods of time. The electrical signals of several microvolts are amplified and counted when above a certain threshold (signal to noise level 3: ...
Computing Action Potentials by Phase Interference in
... In this paper, we solely consider conduction by action potentials and their ability to act as compound phase-ternary objects for an artificial neural network. The basic mechanisms of the action potential are covered elsewhere and both the Hodgkin Huxley [1] and APPulse [2] may be used in this model. ...
... In this paper, we solely consider conduction by action potentials and their ability to act as compound phase-ternary objects for an artificial neural network. The basic mechanisms of the action potential are covered elsewhere and both the Hodgkin Huxley [1] and APPulse [2] may be used in this model. ...
Contributions of Retinal Ganglion Cells to
... (Figure 2a). Further, the response properties of bipolar cells differ among types, and bipolar cells impart these functional properties (e.g., On versus Off, sustained versus transient) upon the RGCs with which they communicate. In this way, bipolar cell terminals establish the first anatomical lami ...
... (Figure 2a). Further, the response properties of bipolar cells differ among types, and bipolar cells impart these functional properties (e.g., On versus Off, sustained versus transient) upon the RGCs with which they communicate. In this way, bipolar cell terminals establish the first anatomical lami ...
Retrograde Signaling in the Development and Modification of
... receive both positive and negative retrograde signals before the decision on synapse formation is made. The presynaptic receptors for these muscle surface proteins and the downstream transduction mechanism involved in growth cone responses are unknown. Because elevation of Ca2/ usually results in an ...
... receive both positive and negative retrograde signals before the decision on synapse formation is made. The presynaptic receptors for these muscle surface proteins and the downstream transduction mechanism involved in growth cone responses are unknown. Because elevation of Ca2/ usually results in an ...
Subthalamic Stimulation-Induced Synaptic Responses in Substantia
... were designed to determine the sources of the excitatory and inhibitory effects. Synaptic potentials were recorded intracellularly from substantia nigra pars compacta dopaminergic neurons in parasagittal slices in response to stimulation of the STN. Synaptic potentials were analyzed for onset latenc ...
... were designed to determine the sources of the excitatory and inhibitory effects. Synaptic potentials were recorded intracellularly from substantia nigra pars compacta dopaminergic neurons in parasagittal slices in response to stimulation of the STN. Synaptic potentials were analyzed for onset latenc ...
Use of lipophilic dyes in studies of axonal pathfinding in vivo
... During the development of the nervous system, axons have to navigate through the preexisting tissue and to establish correct connections with their targets. For this purpose, the axon has a highly motile structure at its tip that acts as a sensor for guidance cues presented by the environment (Vogt ...
... During the development of the nervous system, axons have to navigate through the preexisting tissue and to establish correct connections with their targets. For this purpose, the axon has a highly motile structure at its tip that acts as a sensor for guidance cues presented by the environment (Vogt ...
Neural Coding 2016
... All posters should be posted on Aug 29 in the morning. The posters can stay there for the whole conference but should be removed not later than Thursday Sep 1, 16:00, after the last session. Lunches will be served in the Canteen (“Mensa”) of the University of Cologne, which is across Zülpicher Straß ...
... All posters should be posted on Aug 29 in the morning. The posters can stay there for the whole conference but should be removed not later than Thursday Sep 1, 16:00, after the last session. Lunches will be served in the Canteen (“Mensa”) of the University of Cologne, which is across Zülpicher Straß ...
Limitations of Neural Map Topography for Decoding Spatial
... show in the developing zebrafish that topographic decoding performs very poorly compared with methods that do not rely on topography. This suggests that, although wiring topography could provide a starting point for decoding at a very early stage in development, it may be replaced by more accurate m ...
... show in the developing zebrafish that topographic decoding performs very poorly compared with methods that do not rely on topography. This suggests that, although wiring topography could provide a starting point for decoding at a very early stage in development, it may be replaced by more accurate m ...
Huffman PowerPoint Slides
... Neurons • Neurons are cells that transmit information • Neurons are composed of: – Cell body – Dendrites: extensions that receive information – Axon: extends from cell body, carries electrical potential, sends a chemical message to adjacent neurons © 2000 John Wiley & Sons, Inc. Huffman/Vernoy/Vern ...
... Neurons • Neurons are cells that transmit information • Neurons are composed of: – Cell body – Dendrites: extensions that receive information – Axon: extends from cell body, carries electrical potential, sends a chemical message to adjacent neurons © 2000 John Wiley & Sons, Inc. Huffman/Vernoy/Vern ...
Granger causality analysis of state dependent functional connectivity
... swallowing [1]. Previous studies employing single electrode recording techniques [2], [3] have shown that majority of neurons in MIo show activity related to rhythmic chewing, preswallowing and/or swallowing. However, how functional connectivity in network of spiking neurons changes depending on dif ...
... swallowing [1]. Previous studies employing single electrode recording techniques [2], [3] have shown that majority of neurons in MIo show activity related to rhythmic chewing, preswallowing and/or swallowing. However, how functional connectivity in network of spiking neurons changes depending on dif ...
Neural degeneration mutants in the zebrafish, Danio
... divided into four broad stages: first, induction of the neuroepithelium and formation of the neural plate, a structure characteristic of vertebrates, at the end of gastrulation; second, regionalization or patterning of the neural plate; third, determination and proliferation of neural precursors wit ...
... divided into four broad stages: first, induction of the neuroepithelium and formation of the neural plate, a structure characteristic of vertebrates, at the end of gastrulation; second, regionalization or patterning of the neural plate; third, determination and proliferation of neural precursors wit ...
pdf file - Center for Theoretical Neuroscience
... silencing cortical cells with topical application of muscimol, they could record from the LGN relay cell axons terminating within the corresponding region of layer 4. Surprisingly, the receptive fields of LGN axons recorded within a given vertical penetration formed a region in visual space that was ...
... silencing cortical cells with topical application of muscimol, they could record from the LGN relay cell axons terminating within the corresponding region of layer 4. Surprisingly, the receptive fields of LGN axons recorded within a given vertical penetration formed a region in visual space that was ...
Electrophysiology
Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.