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FREE Sample Here
FREE Sample Here

... Rationale: Astrocytes form scar tissue in brain that acts to impede the regrowth of nerve cells. 2.1-37. Myelination of brain nerve axon membranes is accomplished by a. oligodendrocytes. b. microglia. c. astrocytes. d. neurocytes. e. Schwann cells. Difficulty: 1 Question ID: 2.1-37 Page Ref: 37 Topi ...
Use of a Recombinant Pseudorabies Virus to
Use of a Recombinant Pseudorabies Virus to

... To prevent experimental bias, the facial nerve status was decoded for statistical analysis after cell counts had been collected. In our experiments, five consecutive (50 lm thick) coronal sections from both hemispheres of the animals were processed for PRV immunocytochemistry. Accordingly, in both he ...
12 Touch - pantherFILE
12 Touch - pantherFILE

... electrical pulses, delivered through the skin to nerve fibers, to directly stimulate nerves in the stump that formerly enervated the limb. Spinal cord stimulation uses electrodes surgically inserted within the epidural space of the spinal cord. Deep brain or intracerebral stimulation is considered a ...
Accessory muscle in the hypothenar region: a functional approach
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... branch of the main trunk of the ulnar nerve. An anomalous muscle with similar origin has been described earlier by Netscher and Cohen (1998) with no indication of the insertion pattern. Wingerter et al. (2003) identified a variant, which inserted similarly to the muscle found here, but originated fro ...
Ionic Mechanism of the Slow Afterdepolarization Induced by
Ionic Mechanism of the Slow Afterdepolarization Induced by

... of the slow afterdepolarization induced by muscarinic receptor activation in rat prefrontal cortex. J. Neurophysiol. 80: 1197–1210, 1998. The mammalian prefrontal cortex receives a dense cholinergic innervation from subcortical regions. We previously have shown that cholinergic stimulation of layer ...
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... suggests that at least some of these modulators are tonic elements, normally producing effects over many cycles. Although there is evidence that specific components of a rhythmic cycle may be stimulated or inhibited independently (Maynard, 1966), the qualitative characteristics of the intrinsic, cyc ...
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button - TestbankEbook
button - TestbankEbook

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... fixed group of muscles or the behavioral act that withdraws the finger from the noxious stimulus? This question can be answered by having the subject turn his or her hands over after conditioning is complete, so that now the dorsal surface of the finger is in contact with the electrode. Most subject ...
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Impairment of a parabolic bursting rhythm by the ectopic expression

... bursting activity by rSK2 overexpression is unlikely to be due to reduced spike duration, and is more likely to be due to rSK2-induced slow AHP that decays with a time constant of , 150 ms [14]. It is widely held that slowly activating, voltagedependent currents play a key role in producing the burs ...
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REGENERATION OF AN IDENTIFIED CENTRAL NEURON IN THE

... cord stump at the site of lesion and stopped elongating after 1 month. At this time, supernumerary sprouts first began to emerge from the normally smooth, rounded contours of the cell body. Based on these observations, we propose that axotomized neurons produce membrane at a constant rate. This newl ...
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Trichromatic theory of color vision

... threshold is the smallest level of added or reduced stimulation required to sense that a change in stimulation has occurred. It is the minimum change in stimulation required to detect the difference between two stimuli, so it is also called the “just noticeable difference” (Nittrouer & Lowenstein, 2 ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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