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On the role of primary motor cortex in arm movement
On the role of primary motor cortex in arm movement

... adhoc assumptions about poorly understood mechanisms (see Section 2). In particular, we use linear approximations to the spinal circuitry, muscle force production mechanisms, and kinematics of the multijoint arm. The effects of other descending systems are ignored, although there is evidence (Miller ...
Ventilatory disorders - Chirurgia toracica mini invasiva
Ventilatory disorders - Chirurgia toracica mini invasiva

... play a major role in normal respiratory control during speech, locomotion, and response to stressors including the defence reaction as shown in experimental studies. These neurons are part of a central pattern generator network that controls the periodic activity of bulbar and spinal motor neurons i ...
Cortical and subcortical afferents to the nucleus reticularis tegmenti
Cortical and subcortical afferents to the nucleus reticularis tegmenti

... design of future physiological studies would benefit greatly from a better understanding of the anatomic details. What are needed are injections of tract tracers into the pons to show possible cortical and subcortical afferent sources that previously have not been apparent in “top–down”, cortico-cen ...
xiao-ying-lu-southeast-university
xiao-ying-lu-southeast-university

... 1) Application of MEA for studying brain and heart slices Spontaneous electrical signal or induced signal can be detected from actue brain and heart slices placed on the MEA through MEA system. Then further research about neural system and autonomic nervous system could be carried out. ...
Brain Facts: A Primer On The Brain And Nervous System
Brain Facts: A Primer On The Brain And Nervous System

... with nonidentical siblings of getting the same disease; however, if ...
Neural Mechanisms of Addiction
Neural Mechanisms of Addiction

... the observation that much drug taking, including late relapses, follows exposure to cues previously associated with drug use (Wikler & Pescor 1967, Tiffany 1990, O’Brien et al. 1998). Such drug-associated cues can include external sensory stimuli (e.g., persons, drug paraphernalia, places where drug ...
Basal Ganglia: Mechanisms for Action Selection
Basal Ganglia: Mechanisms for Action Selection

... Without a loop between STN and GPe, the diffuse STN output means that the total excitatory input to the SNr/GPi would grow in proportion to the number of active inputs to the basal ganglia; with a sufficient number of inputs, the excitatory input would grow large enough to overwrite all focussed inh ...
Identity-specific coding of future rewards in the human orbitofrontal
Identity-specific coding of future rewards in the human orbitofrontal

... identity information, then value-related (high vs. low value) patterns of fMRI ensemble activity corresponding to the different outcome identities (sweet vs. savory) should be reliably distinguishable. Using a multivoxel pattern-based searchlight analysis (21), we first computed the value-related re ...
NMDA receptor blockade causes selective prefrontal
NMDA receptor blockade causes selective prefrontal

... regular stimulus sequences, and has emerged as an important tool for probing brain function using noninvasive electroencephalography (EEG) recordings in human subjects. MMNs are difference waves of evoked response potentials (ERPs) to the unexpected deviant stimuli compared to repeated standard stim ...
Differential Activity-Dependent Development of Corticospinal
Differential Activity-Dependent Development of Corticospinal

... and Martin 2005; Martin and Lee 1999; Martin et al. 2004). Even though we understand that activity- and use-dependent processes are important in determining the regional distribution and morphology of CS axon terminals (Friel and Martin 2005; Li and Martin 2001, 2002; Martin et al. 2004), little is ...
Multiple Running Speed Signals in Medial Entorhinal Cortex
Multiple Running Speed Signals in Medial Entorhinal Cortex

... MEC and thus be critical for the generation of grid cells (Hasselmo and Shay, 2014). The two signals necessary for path integration computations have been experimentally demonstrated to be present in MEC. Neurons coding for head direction (HD) arise in an ascending circuit, beginning in the lateral ...
Gpr126 is essential for peripheral nerve development and
Gpr126 is essential for peripheral nerve development and

... mRNA in Gpr126+/– sciatic nerves, but not in wild-type neurons purified from E13.5 dorsal root ganglia (DRG; Fig. 1C,D). Because most mRNAs in the sciatic nerve are transcribed by Schwann cells, this result suggests that, as in zebrafish, mammalian Schwann cells express Gpr126. As expected for a del ...
Measurement of variability dynamics in cortical spike trains
Measurement of variability dynamics in cortical spike trains

... Neurons observed in a living organism typically exhibit temporal changes of their firing rates in response to sensory input, or in relation to behavior. This important feature of neuronal processing can be captured by rate modulated renewal processes, where the process intensity is no longer constan ...
16-2 The Sympathetic Division
16-2 The Sympathetic Division

... • Sympathetic Stimulation and the Release of Ach • Cholinergic (ACh) sympathetic terminals • Innervate sweat glands of skin and blood vessels of skeletal muscles and brain • Stimulate sweat gland secretion and dilate blood ...
Cerebellar control of visceral responses–possible mechanisms
Cerebellar control of visceral responses–possible mechanisms

... Hence, when the cerebellar influence on autonomic function is studied, it is of utmost importance to have full control of and insight into the level of activity in both, the various efferent autonomical pathways and the subordinated effector systems. Otherwise the results are likely to be very confu ...
48-nervous text - Everglades High School
48-nervous text - Everglades High School

... • The membrane potential of a cell can be measured APPLICATION Electrophysiologists use intracellular recording to measure the membrane potential of neurons and other cells. TECHNIQUE A microelectrode is made from a glass capillary tube filled with an electrically conductive salt solution. One end ...
Expression of ml-m4 Muscarinic Acetylcholine Receptor Proteins in
Expression of ml-m4 Muscarinic Acetylcholine Receptor Proteins in

... innervation. Thus, there were several goals of the present study. The first goal was to determine the light microscopic localization of mlm4 immunoreactivity in the dorsal hippocampus of the rat. Secondly, we sought to determine the magnitude and distribution of changes in subtypes that occur follow ...
Experimental Models of Parkinson`s Disease: Insights from Many
Experimental Models of Parkinson`s Disease: Insights from Many

... the first agent discovered that had specific neurotoxic prop- ...
Information processing in a neuron ensemble with the multiplicative
Information processing in a neuron ensemble with the multiplicative

... approximation, reports in the literature indicate some more details, particularly in relation to the term kij : One study (Zohary et al., 1994) suggested that the correlation between neurons, whose preferred stimuli are similar, is significantly higher than that between unsimilar neurons, while anot ...
Receptors in lateral hypothalamic area involved in - AJP
Receptors in lateral hypothalamic area involved in - AJP

... activity before the stimulus artifact. After the stimulus artifact, an excitatory sympathetic response was identified in which activity was calculated to be one standard deviation above baseline activity for five consecutive bins (1 bin 5 2 ms). The absolute response was determined by subtracting th ...
Can the negative deflections found with EEG on frontocentral
Can the negative deflections found with EEG on frontocentral

... Electroencephalography (EEG) is an non-invasive method to measure brain activity in healthy subjects. By measuring the electric field on the subjects scalp, researchers are trying to identify different processes, brain states, brain oscillations or find markers of mental diseases. An event-related p ...
Systematic Regional Variations in the Loss of Cortical Cholinergic
Systematic Regional Variations in the Loss of Cortical Cholinergic

... detected. There was, however, marked regional variations in the extent of this loss in different cortical areas. Cortical areas within the temporal lobe, particularly the temporal association areas, displayed a dramatic loss of cholinergic fibers. By contrast the anterior cingulate cortex, primary v ...
Exposure to As-, Cd-, and Pb-Mixture Induces Ab, Amyloidogenic
Exposure to As-, Cd-, and Pb-Mixture Induces Ab, Amyloidogenic

... 0.38, 0.098, and 0.22 ppm or 10 times of each, respectively, from gestation-05 to postnatal day-180. We identified dosedependent increase in amyloid-beta (Ab) in frontal cortex and hippocampus as early as post-weaning. The effect was strongly significant during early-adulthood, reaching levels compa ...
The Crash Course in Head, Neck, and Arm By Mike Sughrue
The Crash Course in Head, Neck, and Arm By Mike Sughrue

... Somatic Motor nuclei are named for the nerve they contribute to (i.e. the III has an Oculomotor nucleus, the VII a facial nucleus etc). The only exception is the Nucleus Ambiguus, which is the somatic motor nucleus for IX and X. There are 4 peripheral Ganglia in the head (Ciliary, Pterygopalatine, S ...
Promega Notes: Primer Pairs for Neurotrophic Factor mRNA Analysis
Promega Notes: Primer Pairs for Neurotrophic Factor mRNA Analysis

... TrkA receptor (1). Many neuronal types, especially sympathetic neurons cultured from neonatal animals, require NGF for survival (2). Moreover, NGF 'knockout' mice exhibit a selective loss of neurons in the sympathetic ganglia and dorsal root ganglia (2). Increasingly, NGF is being recognized for its ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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