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cerebellum
cerebellum

... – Each parallel fiber forms excitatory synaptic contacts with numerous Purkinje cells. – All output from the cerebellar cortex is carried by the axons of Purkinje cells into the cerebellar wm. – The Purkinje cells form inhibitory synapses onto the deep cerebellar nuclei and vestibular nuclei, which ...
Anti-Apoptotic Proteins in Nerve Cell Survival and
Anti-Apoptotic Proteins in Nerve Cell Survival and

... Genetical studies suggest that ces-1 and ces-2 (ces, cell death specification) regulate a subset of cell death in C. Elegans since mutations in these genes block the death of certain neural cells (Ellis and Horvitz, 1991a). However, mutations in ces-1 and ces-2 do not affect cell death in all cell ...
Imaging Auditory Representations of Song and Syllables in
Imaging Auditory Representations of Song and Syllables in

... was visualized under 2p imaging. Different HVC cell types were identified based on the presence of retrograde labeling and/or their intrinsic electrophysiological properties for in vitro and in vivo experiments and, for in vivo experiments, by their song-evoked electrophysiological properties (Dutar ...
autonomic nervous system
autonomic nervous system

... cells (from the Greek word for “glue”), another special type of cell found in the nervous system. • Glial cells have several functions: removing waste, occupying vacant space when neurons die, guiding the migration of neurons during brain development, and insulation. Copyright © 2010 Pearson Educati ...
Schwann Cell Surfaces but Not Extracellular Matrix Organized by
Schwann Cell Surfaces but Not Extracellular Matrix Organized by

... beena perplexing problem in neurobiology. Recent studieshave shown that componentsof the environment through which injured nervesgrow influence the extent of regeneration.In a direct comparison, segmentsof sciatic nerve, but not of optic nerve, supported PNS neurite outgrowth, demonstrating the fail ...
mGluR-dependent persistent firing in entorhinal cortex layer III neurons SYNAPTIC MECHANISMS Motoharu Yoshida,
mGluR-dependent persistent firing in entorhinal cortex layer III neurons SYNAPTIC MECHANISMS Motoharu Yoshida,

... Persistent firing is believed to be a crucial mechanism for memory function including working memory. Recent in vivo and in vitro findings suggest an involvement of metabotropic glutamate receptors (mGluRs) in persistent firing. Using whole-cell patch-recording techniques in a rat entorhinal cortex ...
Receptor Tyrosine Kinases: Molecular Switches Regulating CNS
Receptor Tyrosine Kinases: Molecular Switches Regulating CNS

... polypeptide growth factors, cytokines, and hormones. RTKmediated signals play pivotal and diverse roles in the regulation of various physiological functions, ranging from cell proliferation, differentiation, cell adhesion, cell migration, survival, and apoptosis [34, 35]. In the human genome alone, 5 ...
Relationship between muscle output and functional MRI
Relationship between muscle output and functional MRI

... trial was performed at each level, and the time during which the force was on the target was about 5 s for each contraction. At least a 30-s rest was provided between contractions. Five subjects performed the five levels in ascending order and the other five subjects in descending order. The purpose ...
basic mechanisms of sleep
basic mechanisms of sleep

... LDT and PPT with strong evidence that a subset of these are cholinergic (6). In rodent brainstem slices, mesopontine neurons can be divided according to their membrane current characteristics into types I, II and III, with types II and III being cholinergic and projecting to the thalamus (6). Many r ...
Neural Control of Eye Movements
Neural Control of Eye Movements

... Donder’s and Lis3ng’s Laws of Torsion •  Donder’s Law - Each gaze direcDon has a unique torsional posture, no maeer what path the eye took to get there. •  Lis3ng’s Law – Any eye posiDon can be described by rotaDon of the eye from primary posiDon about a single axis lying in a specific fronto-pa ...
Making Mirrors: Premotor Cortex Stimulation
Making Mirrors: Premotor Cortex Stimulation

... a movement involving a different muscle. After such training, action observation enhances MEPs from the nonmatching muscle (Catmur, Walsh, & Heyes, 2007). It is not known whether these counter-mirror effects involve the same brain areas that are involved in mirror effects. A demonstration that coun ...
Paper
Paper

... monkey (Cebus apella). The resulting pattern of labeled cells was assessed in relation to the three-dimensional geometry of the claustrum, as well as recent reports of claustrum-prefrontal connections in other primates. Claustrum-prefrontal projections were extensive, and largely concentrated in the ...
Locally evoked potentials in slices of the rat nucleus - UvA-DARE
Locally evoked potentials in slices of the rat nucleus - UvA-DARE

... followed by a small positive component, P1 (Fig. 2A), N2 by a relatively long-lasting positive wave, P2. This field potential could be recorded in all subregions of the Acb, although P2 was most clearly seen in the region surr o u n d i n g the A C and in other border regions of the Acb. T h e posit ...
Brain-Derived Neurotrophic Factor Reduces Amyloidogenic
Brain-Derived Neurotrophic Factor Reduces Amyloidogenic

... replicate Western blots revealed a statistical significant reduction in relative receptor levels from 100 ⫾ 26.1% in wild types (n ⫽ 4) to 56.0 ⫾ 21.6% in HT mice (n ⫽ 5; p ⬍ 0.05, Student’s t test). Again, a correlation with BDNF levels was specific for SORLA and not seen for sortilin or synaptophy ...
How do dendrites take their shape?
How do dendrites take their shape?

... growth cone dynamics strongly suggest that NGF can regulate local cytoskeletal changes without the need for transcriptional regulation. It will be interesting to see whether local applications of neurotrophins can selectively induce nearby dendrites to grow and turn as the neurites of the cultured n ...
Reward and Reinforcement I 1. Which of the following statements is
Reward and Reinforcement I 1. Which of the following statements is

... D. when the animal is presented with a stimulus previously paired with food E. B and D are TRUE A. FALSE VTA neurons increase their firing to appetitive (rewarding) stimuli B. TRUE VTA neurons increase their firing to appetitive (rewarding) stimuli C. FALSE VTA neurons increase their firing to appet ...
Age-Related Uptake of Heavy Metals in Human Spinal Interneurons
Age-Related Uptake of Heavy Metals in Human Spinal Interneurons

... the disease become clinically apparent and could no longer be detectable at the time of post mortem examination. Furthermore, after death from ALS/MND a severe loss of motoneurons is usually present, and the remaining motoneurons may have survived because they did not contain the toxicant. Finally, ...
A precocious adult visual center in the larva defines the unique optic
A precocious adult visual center in the larva defines the unique optic

... larvae of tiger beetles (Cicindelinae) suggest that this neuropil can develop in the larva. Relays from two pairs of large single-lens eyes (stemmata), via an underlying larval lamina neuropil, supply a reniform neuropil (called the tectum [1]) equipped with wide-field tangential neurons that are tu ...
document988
document988

... pressing the pedal. The majority (73%) of these units was activated during only one behavioural cycle, either at the front or the rear wall. The remainder (27%) were activated during both behavioural cycles. L units could be activated during the rabbit's approach to one or both feeders, and also dur ...
The Neurobehavioral Nature of Fishes and the
The Neurobehavioral Nature of Fishes and the

... organization, there are great differences across vertebrate taxa in the structure and complexity of the brain (Butler and Hodos, 1996; Nieuwenhuys et al., 1998a). A principal difference between mammalian brains and those of other vertebrates is the expansion and complexity of the mammalian cerebral ...
Somatic and Special Senses
Somatic and Special Senses

... http://thebrain.mcgill.ca/flash/d/d_02/d_02_m/d_02_m_vis/d_02_m_vis_1a.jpg ...
Anticipated synchronization in neuronal circuits
Anticipated synchronization in neuronal circuits

... AS was also verified in experiments with electronic circuits [13, 14, 15, 16]. The electronic circuits allow for a real-time anticipation of even strongly irregular signals. It was found that synchronization of the driven circuit with chaotic future states of the driving circuit is insensitive to si ...
Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling
Regulation of thalamocortical axon branching by BDNF and synaptic vesicle cycling

... transfected with EYFP or EGFP encoding plasmids so individual axons could be observed in the neocortical explant (Figures 1A,B). As demonstrated previously, thalamocortical axons branched extensively in the neocortical explant after 14 DIV (Figure 1E; Yamamoto et al., 1992; Uesaka et al., 2007). The ...
The Neuropsychology of Sigmund Freud
The Neuropsychology of Sigmund Freud

... this the third great step in the study of memory processes (1950). According to Rapaport, the first of these steps was the experimental study of rote memory by Ebinghaus, the second was the demonstration by the Gestalt investigators that remembering is lawfully organized, and the third is the notion ...
Individual olfactory sensory neurons project into more than one
Individual olfactory sensory neurons project into more than one

... 2D). Once the axon arrived in the olfactory bulb, it bifurcated into two axonal branches, a and b. Downstream, each of these branches bifurcated again giving rise to subbranches a1 and a2, as well as b1 and b2. The subbranches a1 and b1 innervated one glomerulus, and subbranches a2 and b2 ran into a ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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