
Individual olfactory sensory neurons project into more than one
... 2D). Once the axon arrived in the olfactory bulb, it bifurcated into two axonal branches, a and b. Downstream, each of these branches bifurcated again giving rise to subbranches a1 and a2, as well as b1 and b2. The subbranches a1 and b1 innervated one glomerulus, and subbranches a2 and b2 ran into a ...
... 2D). Once the axon arrived in the olfactory bulb, it bifurcated into two axonal branches, a and b. Downstream, each of these branches bifurcated again giving rise to subbranches a1 and a2, as well as b1 and b2. The subbranches a1 and b1 innervated one glomerulus, and subbranches a2 and b2 ran into a ...
Chapter 1: The Muscle Spindle and the Central
... fine axonal elongated end organs called trail endings (gamma nerve fibers account for 30% of the efferent nerve supply). The motor end plates occur only on the nuclear bag fibers (each fiber having several) and the trail endings occur only on the nuclear chain. These endings are supplied by efferent ...
... fine axonal elongated end organs called trail endings (gamma nerve fibers account for 30% of the efferent nerve supply). The motor end plates occur only on the nuclear bag fibers (each fiber having several) and the trail endings occur only on the nuclear chain. These endings are supplied by efferent ...
How humans distinguish between smells
... The particular axons that are activated depend upon which receptor protein is targeted. Each cell produces only one type of receptor protein. In humans, there are approximately 350 different types of receptor proteins produced (Axel, 2006). In other mammals, such as mice, the number of different re ...
... The particular axons that are activated depend upon which receptor protein is targeted. Each cell produces only one type of receptor protein. In humans, there are approximately 350 different types of receptor proteins produced (Axel, 2006). In other mammals, such as mice, the number of different re ...
... dimensions—for example, when a squirrel hunts for acorns on the ground—is similar to what is observed in the cortex, where the space is multidimensional, and many searches may take place in parallel (discussed in Section 5). The theory presented here is based on evidence from multiple disciplines, f ...
Leptin Receptor Signaling and Action in the Central Nervous System
... While several assays detect LRb expression within the CNS, each of these has limitations that prompted us to seek a more facile system for identifying LRb-expressing neurons. In situ hybridization histochemistry (ISH) for LRb is difficult, more so if done in combination with immunohistochemistry (IH ...
... While several assays detect LRb expression within the CNS, each of these has limitations that prompted us to seek a more facile system for identifying LRb-expressing neurons. In situ hybridization histochemistry (ISH) for LRb is difficult, more so if done in combination with immunohistochemistry (IH ...
Modulation of Inhibitory Synaptic Potentials in the Piriform Cortex
... In these equations, W represents the average strength of excitatory synapses arising from cortical pyramidal cells and synapsing on other excitatory neurons. If neuronal output is in spikes/ms, then synaptic strength reflects the change in membrane voltage per spike (mV/ spike) because of the membra ...
... In these equations, W represents the average strength of excitatory synapses arising from cortical pyramidal cells and synapsing on other excitatory neurons. If neuronal output is in spikes/ms, then synaptic strength reflects the change in membrane voltage per spike (mV/ spike) because of the membra ...
USF Hyperbaric Biomedical Research Laboratory
... positioned in the CA1 region of the hippocampal slice for measuring pre- and post-synaptic field potentials activated by electrical stimulation of CA3 axons before, during and following exposure to hyperbaric oxygen. Bottom Panel—Three electrically driven microdrives are used to position the various ...
... positioned in the CA1 region of the hippocampal slice for measuring pre- and post-synaptic field potentials activated by electrical stimulation of CA3 axons before, during and following exposure to hyperbaric oxygen. Bottom Panel—Three electrically driven microdrives are used to position the various ...
the effects of microstimulation and microlesions in the ventral and
... elicited by microstimulation were readily observed on slow sweep speed traces. The data also were displayed at faster sweep speeds with the oscilloscope triggered by the recorded stimulus pulses. Whenever a short latency response to stimulation was observed in a single trial in any of the recorded s ...
... elicited by microstimulation were readily observed on slow sweep speed traces. The data also were displayed at faster sweep speeds with the oscilloscope triggered by the recorded stimulus pulses. Whenever a short latency response to stimulation was observed in a single trial in any of the recorded s ...
Time-Dependent Activation of Feed-Forward Inhibition in
... FIG. 2. Effect of picrotoxin on the responses to visual stimuli of the LGMD and of neuronal populations recorded in the medulla. A: 5 sample traces of intracellular recordings from the LGMD in response to a looming stimulus (l/!v! & 30 ms, illustrated in the top panels) are shown at the bottom. The ...
... FIG. 2. Effect of picrotoxin on the responses to visual stimuli of the LGMD and of neuronal populations recorded in the medulla. A: 5 sample traces of intracellular recordings from the LGMD in response to a looming stimulus (l/!v! & 30 ms, illustrated in the top panels) are shown at the bottom. The ...
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... 52. Stimulus A depolarizes a neuron just barely above the threshold. Stimulus B depolarizes a neuron to 10 mV beyond threshold. What can we expect to happen? A. Stimulus B will produce an action potential that is conducted at a faster speed than A. B. Stimulus B will produce an action potential of g ...
... 52. Stimulus A depolarizes a neuron just barely above the threshold. Stimulus B depolarizes a neuron to 10 mV beyond threshold. What can we expect to happen? A. Stimulus B will produce an action potential that is conducted at a faster speed than A. B. Stimulus B will produce an action potential of g ...
body proportions in infancy and early childhood
... • Newborns can discriminate between smells. • Infants show innate preferences for some tastes: – Preference for human milk – Preference for sugar to other substances ...
... • Newborns can discriminate between smells. • Infants show innate preferences for some tastes: – Preference for human milk – Preference for sugar to other substances ...
Long-term potentiation in the anterior cingulate cortex and chronic
... chronic pain. In addition, opioids have many unwanted side effects after prolonged use. Recent integrative neuroscience studies have found that chronic pain and acute pain operate through different central mechanisms [1]. Inhibitors that reduce pain transmission do not prevent the induction of chron ...
... chronic pain. In addition, opioids have many unwanted side effects after prolonged use. Recent integrative neuroscience studies have found that chronic pain and acute pain operate through different central mechanisms [1]. Inhibitors that reduce pain transmission do not prevent the induction of chron ...
Properties and Functional Role of Voltage
... Patch pipettes were pulled from borosilicate glass tubing (outer diameter, 1.65 mm; inner diameter, 0.75 mm; Dagan, Minneapolis, MN) and heat polished before use. Pipettes were filled with an internal solution consisting of (in mM): 140 KCl, 2 MgCl2, 10 EGTA, 2 Na2 ATP, 10 HEPES, pH adjusted to 7.3 ...
... Patch pipettes were pulled from borosilicate glass tubing (outer diameter, 1.65 mm; inner diameter, 0.75 mm; Dagan, Minneapolis, MN) and heat polished before use. Pipettes were filled with an internal solution consisting of (in mM): 140 KCl, 2 MgCl2, 10 EGTA, 2 Na2 ATP, 10 HEPES, pH adjusted to 7.3 ...
Placing prediction into the fear circuit
... neurons, and studies have shown that LA neurons respond preferentially to an unexpected rather than expected US [20,21]. This suggests that LA neurons receive instructive teaching inputs that encode an aversive prediction error signal; if so, from where might this teaching signal derive? Several stu ...
... neurons, and studies have shown that LA neurons respond preferentially to an unexpected rather than expected US [20,21]. This suggests that LA neurons receive instructive teaching inputs that encode an aversive prediction error signal; if so, from where might this teaching signal derive? Several stu ...
Physiology of endocrine system
... gonadotropins) because they stimulate the gonads, are both secreted by the same cells. ...
... gonadotropins) because they stimulate the gonads, are both secreted by the same cells. ...
Dopamine in Schizophrenia
... in the treatment of amphetamine-induced psychosis and schizophrenia [neuroleptics or antipsychotic drugs (APDs)] decreased DA activity, and their clinical potency was correlated with their potency in blocking D2 receptors (Carlsson and Lindquist 1963; Creese et al. 1976; Hyttel et al. 1985; Farde et ...
... in the treatment of amphetamine-induced psychosis and schizophrenia [neuroleptics or antipsychotic drugs (APDs)] decreased DA activity, and their clinical potency was correlated with their potency in blocking D2 receptors (Carlsson and Lindquist 1963; Creese et al. 1976; Hyttel et al. 1985; Farde et ...
Neurological mechanisms involved in orthodontic tooth movement
... information) expression is noted ipsilaterally in the trigeminal subnucleus caudalis and bilaterally in the lateral parabranchial nucleus. These fos-like immunoreactive neurons are distributed in other brain regions such as the neocortex, dorsal raphe, and thalamic nucleus.[21] Nociceptive informati ...
... information) expression is noted ipsilaterally in the trigeminal subnucleus caudalis and bilaterally in the lateral parabranchial nucleus. These fos-like immunoreactive neurons are distributed in other brain regions such as the neocortex, dorsal raphe, and thalamic nucleus.[21] Nociceptive informati ...
Neural substrates for conditioned taste aversion in the rat.
... Several researchers [8.141.169] have shown that reliable CTAs can be established when the CS presentation coincides with the injection of LiC1 (US), or even when the US precedes the CS by 5 to 10 rain. In other words, when the US precedes the CS more than 10 min. no reliable CTAs can be formed. Comp ...
... Several researchers [8.141.169] have shown that reliable CTAs can be established when the CS presentation coincides with the injection of LiC1 (US), or even when the US precedes the CS by 5 to 10 rain. In other words, when the US precedes the CS more than 10 min. no reliable CTAs can be formed. Comp ...
Synapse formation in developing neural circuits.
... Most of the subsequent synaptic studies in the nineteenth century and earlier half of the twentieth century also focused around the functionality of synapses, or synaptic transmission. It is therefore befitting that the actual term ‘‘synapse’’ was not coined by a neuroanatomist, but by a physiologis ...
... Most of the subsequent synaptic studies in the nineteenth century and earlier half of the twentieth century also focused around the functionality of synapses, or synaptic transmission. It is therefore befitting that the actual term ‘‘synapse’’ was not coined by a neuroanatomist, but by a physiologis ...
Retinal Ganglion Cell Layer Thinning Within One Month of
... a reliable measure of retinal neuronal structure using three-dimensional segmentation. Thinning develops within 1 to 2 months of onset, which is prior to RNFL swelling resolution. This suggests GCLþIPL measurement is better than the RNFL thickness to use as biomarker of early structural loss in NAIO ...
... a reliable measure of retinal neuronal structure using three-dimensional segmentation. Thinning develops within 1 to 2 months of onset, which is prior to RNFL swelling resolution. This suggests GCLþIPL measurement is better than the RNFL thickness to use as biomarker of early structural loss in NAIO ...
Learned Movements Elicited by Direct Stimulation of Cerebellar
... antidromic activation of mossy fibers, we blocked the mossy fiber transmission ventral to the stimulation electrode in two animals. If the CS information is transmitted via the mossy fibers, this should abolish responses to the forelimb CS but leave responses to MCP stimulation unaffected. A micropi ...
... antidromic activation of mossy fibers, we blocked the mossy fiber transmission ventral to the stimulation electrode in two animals. If the CS information is transmitted via the mossy fibers, this should abolish responses to the forelimb CS but leave responses to MCP stimulation unaffected. A micropi ...
Encoding of target direction and speed during visual instruction and
... in terms of the amount of ®ring variability explained because the number of predictors was equal. A highly conservative criterion of 10 consecutive bins (200 ms) with an R2 > 0.2 (P < 0.05) for each bin was required to accept a relationship between the ®ring and a parameter as signi®cant. This stric ...
... in terms of the amount of ®ring variability explained because the number of predictors was equal. A highly conservative criterion of 10 consecutive bins (200 ms) with an R2 > 0.2 (P < 0.05) for each bin was required to accept a relationship between the ®ring and a parameter as signi®cant. This stric ...
Nitric Oxide Synthase Protein and mRNA Are
... of NOS. Higher magnifications emphasize the colocalization of these ...
... of NOS. Higher magnifications emphasize the colocalization of these ...
Probability of Transmitter Release at Neocortical
... states. When MK-801 is present in the medium, it blocks irreversibly some of the open channels, thus accelerating the EPSC decay. Despite its simplicity, this model describes the EPSC kinetics reasonably well, and it has been applied successfully for calculating the fraction of blocked channels (FB) ...
... states. When MK-801 is present in the medium, it blocks irreversibly some of the open channels, thus accelerating the EPSC decay. Despite its simplicity, this model describes the EPSC kinetics reasonably well, and it has been applied successfully for calculating the fraction of blocked channels (FB) ...
Median Nerve Conduction Velocity
... Although the IXTA can generate up to 100 Volts, the current delivered by the unit is limited to a maximum of 20 milliamperes, for a maximum duration of 10 milliseconds per pulse, and a maximum frequency of 50 pulses per second (Hz). At these levels, the maximum amount of power delivered by the IXTA ...
... Although the IXTA can generate up to 100 Volts, the current delivered by the unit is limited to a maximum of 20 milliamperes, for a maximum duration of 10 milliseconds per pulse, and a maximum frequency of 50 pulses per second (Hz). At these levels, the maximum amount of power delivered by the IXTA ...