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lmmunocytochemical Localization of Protein Kinase C lsozymes in
lmmunocytochemical Localization of Protein Kinase C lsozymes in

... isozyme-specific antibodies from the polyclonal antibodies previously prepared in goat against a mixture of rat brain PKC isozymes by immunoabsorbtion according to the method of Olmsted (198 1). While the unfractionated polyclonal&tibodies recognized all 3 types of PKC, the purified antibodies prefe ...
Full Article
Full Article

... and they were manifested by well-defined varicosities apparently lying directly on the apposed neuron. To be considered apposed by an axon, a neuron needed to exhibit only one, well-characterized, axonal varicosity on its soma or one of its dendrites. We inferred the existence of synapses by close a ...
audition - Neuroanatomy
audition - Neuroanatomy

... The Audiogram The auditory threshold curve provides detailed information about how quiet a sound we can detect. In practice, however, we’re usually more concerned about how well or poorly a person’s hearing might be, relative to normal, so such data as these are converted to a different and clinical ...
Neural Crest - bthsresearch
Neural Crest - bthsresearch

... – Cartilage, bone, cranial neurons, glia and connective tissues of the face, bones of middle ear, jaw, tooth primordia ...
Gross Anatomy
Gross Anatomy

... Reticular formation: motor control, ...
Transfer Effects and Conditional Learning in Rats With Selective
Transfer Effects and Conditional Learning in Rats With Selective

... Rats were divided into two groups: those receiving cholinergic medial septal lesions (MS/VDB, n ⫽ 12) and surgical controls (CONT, n ⫽ 12). Prior to surgery, each rat was deeply anaesthetized by an intramuscular injection of a ketamine–xylazine mixture (80 mg/kg ketamine and 5 mg/kg xylazine; Phoeni ...
Alterations of Mitochondria and Golgi Apparatus Are
Alterations of Mitochondria and Golgi Apparatus Are

... are the result of the post-translational proteolysis of the APP [18], by concerted actions of βand γ-secretases [19]. The amyloidogenic pathway for APP is initiated by β- site amyloid precursor proteincleavage enzyme 1 (BACE- 1), resulting in the generation of the intermediate product sAPPβ [20]. γ ...
Complete Pattern of Ocular Dominance Columns in Human Primary
Complete Pattern of Ocular Dominance Columns in Human Primary

... from six subjects of European descent with a history of monocular visual loss. They were patients of one of the authors (J.C.H.). Each patient, or surviving next-of-kin, provided written permission for postmortem histological examination, following a protocol approved by an Institutional Review Boar ...
Read Neuroglia
Read Neuroglia

... dictionary - looking for online definition of neuroglia in the medical dictionary neuroglia explanation free what is neuroglia meaning of neuroglia medical term, purinoceptors on neuroglia read by qxmd - purinergic transmission is one of the most ancient and widespread extracellular signalling syste ...
Glial heterogeneity: the increasing complexity of the brain
Glial heterogeneity: the increasing complexity of the brain

... Indeed, numerous examples of glial heterogeneity exist. This is especially conspicuous in the morphological specialization of astrocytes (.  Fig. 2). In some regions such as the cerebellar cortex and the retina, they exhibit a radial orientation. In contrast, astrocytes in the cortex or hippocampus ...
Cells of the Nervous System
Cells of the Nervous System

... 1.Name and describe the parts of a neuron and explain their functions. 2.Describe the supporting cells of the central and peripheral nervous systems and describe and explain the importance of the blood–brain barrier. 3.Briefly describe the neural circuitry responsible for a withdrawal reflex and its ...
The physiological role of orexin/hypocretin neurons in the regulation
The physiological role of orexin/hypocretin neurons in the regulation

... The hypothalamus monitors body homeostasis and regulates various behaviors such as feeding, thermogenesis, and sleeping. Orexins (also known as hypocretins) were identified as endogenous ligands for two orphan G-protein-coupled receptors in the lateral hypothalamic area. They were initially recognize ...
Dopamine Modulates the Function of Group II and Group III
Dopamine Modulates the Function of Group II and Group III

... dendrites (Bjorklund and Lindvall, 1975; Cheramy et al., 1981; Rice et al., 1997). By its actions on D2 autoreceptors located on SNc DA-ergic neurons, somatodendritically released DA can modulate SNc cell firing and subsequent DA release in the striatum (Santiago and Westerink, 1991). Furthermore, i ...
A táplálékfelvétel, a só- és vízháztartás neuroanatómiája
A táplálékfelvétel, a só- és vízháztartás neuroanatómiája

... NEUROPEPTIDE Y (NPY) - NPY is the most potent orexigenic agent known - NPY neurons in the arcuate nucleus co-express AgRP - arcuate preproNPY mRNA level is increased by food deprivation - arcuate NPY cells express leptin receptors (Ob-Rb form) - expression of NPY mRNA in the arcuate nucleus is inhi ...
Impact of correlated inputs to neurons
Impact of correlated inputs to neurons

... Received: 9 July 2013 / Revised: 2 April 2014 / Accepted: 4 April 2014 © The Author(s) 2014. This article is published with open access at Springerlink.com ...
Article Full Text PDF
Article Full Text PDF

... types of synapses: electrical inhibitory, electrical excitatory, chemical inhibitory, and chemical excitatory (Furshpan and Furukawa, 1962; Furukawa and Furshpan, 1963; Korn et al., 1990). They receive afferent sensory inputs from a variety of sources, notably auditory, and also many inhibitory inpu ...
Immunocytochemical Distribution of the
Immunocytochemical Distribution of the

... compared with primary sensory and motor cortices. Similar regional and laminar distributions of CB1-IR axons were also present in the human neocortex. CB1-IR axons had more prominent varicosities in human tissue, but this difference appeared to represent a postmortem effect as similar morphological ...
Single-Trial Decoding of Visual Attention from Local Field Potentials
Single-Trial Decoding of Visual Attention from Local Field Potentials

... Figure 2. Decoding of LFP. This figure represents the single-trial decoding accuracy as a function of task epoch for each LFP frequency band. Only correct trials from “Target” trials were included. Cutoff frequencies for each band are indicated on the y-axis. The results were aligned to cue onset or ...
Cellular and Molecular Mechanisms of Learning and Memory
Cellular and Molecular Mechanisms of Learning and Memory

... which a reinforcer is contingent upon an animal’s response, Pavlovian paradigms have been more useful for modeling associative learning on a cellular level, although some attempts are being made at determining the pathways involved in operant conditioning (15). Associative Learning in Aplysia Pavlov ...
Neuroanatomical correlates of the near response: voluntary
Neuroanatomical correlates of the near response: voluntary

... information by lacking directionality in focusing power, i.e. no direct information about the over- or under-focusing of a target. Yet, the visual system is exquisitely sensitive to dioptric blur (Legge et al., 1987). Secondary cues (e.g. chromatic aberration) must be processed in parallel within a ...
Trapped in endoderm-1 Reveals a Novel Role for Fruitless in
Trapped in endoderm-1 Reveals a Novel Role for Fruitless in

... 1950). Instinctive or innate behaviors are stereotyped behaviors of an organism induced by specific sensory stimuli, also called a fixed action pattern. Innate behaviors are capable of being performed without training. The study of these behaviors offers the advantage of dedicated neurological pathw ...
Immunohistochemical description of the endogenous cannabinoid
Immunohistochemical description of the endogenous cannabinoid

... lum, the substantial down-regulation of DAGL␤ contrasts with the strong staining of DAGL␣ in the Purkinje cell dendritic field (Bisogno et al., 2003). For this study, we selected NAPE-PLD as the anandamide-synthesizing enzyme. A recent paper described the molecular characterization of NAPE-PLD; its a ...
Pathways for emotions and memory prefrontal cortices in the rhesus monkey
Pathways for emotions and memory prefrontal cortices in the rhesus monkey

... of the prefrontal cortex (Barbas and Pandya, 1989). MPAll, OPAll, OPro and OLF refer to architectonic areas. Other letter combinations refer to cases (see Table 1). The injection site patterns refer to the type of tracer used: gray, HRP-WGA; black area, BDA; black outline, [3 H] amino acids. ...
On the role of primary motor cortex in arm movement
On the role of primary motor cortex in arm movement

... adhoc assumptions about poorly understood mechanisms (see Section 2). In particular, we use linear approximations to the spinal circuitry, muscle force production mechanisms, and kinematics of the multijoint arm. The effects of other descending systems are ignored, although there is evidence (Miller ...
Ontogeny, Compartmentation, and Turnover of Spectrin lsoforms in
Ontogeny, Compartmentation, and Turnover of Spectrin lsoforms in

... compartmentation comes from its ontogeny. Membrane-associated cuyspectrin is present at birth at its adult levels, but cytoplasmic a&spectrin is expressed only following the second postnatal week. Similarly, the 4-fold difference in cytoplasmic ay-spectrin content across brain regions develops durin ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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