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Supraspinal control of ejaculation
Supraspinal control of ejaculation

... Percentage of galanin cells that were Fos-ir after Home Cage, Anestrous Female, Mounts, M+I, 1 Ejac., 2 Ejacs ...
View Full Page PDF
View Full Page PDF

... cells becomes asymmetric (skewed) with experience, a prediction that was confirmed experimentally (673). This example illustrates how a learning mechanism specifically depends on temporal correlations of neural firing activity. Correlated activity (coherent rhythms in particular) also plays an impor ...
Effects of galanin on wide-dynamic range neuron activity
Effects of galanin on wide-dynamic range neuron activity

... findings showing that galanin expression in primary sensory neurons was up-regulated, and that the inhibitory action of galanin enhanced after sciatic nerve injury [18]. Galantide (galanin (1–13)–substance P (5–11) amide), the antagonist of galanin, can block the inhibitory actions of galanin [19]. ...
Downloadable Full Text - DSpace@MIT
Downloadable Full Text - DSpace@MIT

... on a different subpopulation of VTA DA neurons as well as on GABAergic cells in the RMTg. ChR2-EYFP expressing fibers from the LHb were found in medial posterior VTA in close proximity to DA neurons projecting to mPFC as well as in the RMTg (Supplementary Fig. 12, 13). Importantly, light-evoked EPSC ...
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descending projections from the trigeminal ganglion and
descending projections from the trigeminal ganglion and

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... Inc. All rights reserved. ...
attention - CMU Graphics
attention - CMU Graphics

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... One type of monitoring approach is to use a microelectrode -- a small, microscopic probe typically made of glass or metal -- to record the number of action potentials a dopamine neuron generates. This technique is called electrophysiology or monitoring the “electrical functioning” of the neuron. The ...
Specialized Elements of Orbitofrontal Cortex in Primates
Specialized Elements of Orbitofrontal Cortex in Primates

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Role of Feedforward and Feedback Projections in Figure
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kbook or W NEUROLOGICAL DISORDERS

... How likely is it that once we know exactly how the brain functions that we will be able to control another person’s brain? It sounds like science fiction, but we can actually do it right now, even with the limited knowledge we have. Transcranial magnetic stimulation (TMS) uses magnetic energy to sen ...
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Measurement of variability dynamics in cortical spike trains

... et al., 1967a, b; Tuckwell, 1988). Of particular interest is the class of renewal processes (Cox, 1962). Here, the intervals Xi between successive points (i.e. spikes) are independent and identically distributed (i.i.d.) with a fixed interval distribution f (x), implying a constant point process int ...
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Is Cell Death Primary or Secondary in the Pathophysiology of

... shown by others in DLB and Parkinson’s disease [41,50]. Looking at postsynaptic markers, an almost complete loss of drebrin was observed. Drebrin is an f-actin-binding postsynaptic protein known to be involved in the formation of dendritic spines [51]. By visualizing the dendritic tree of single cel ...
Review The Neural Basis of Perceptual Learning
Review The Neural Basis of Perceptual Learning

... outside the temporal lobe. One form of implicit memory, perceptual learning, involves improving one’s ability, with practice, to discriminate differences in the attributes of simple stimuli. Perceptual learning involves areas of neocortex upstream in the visual pathway from the temporal lobe, extend ...
Developmental Changes Revealed by Immunohistochemical
Developmental Changes Revealed by Immunohistochemical

... zones are present (Fig. IB). From ventricle to outer brain surface these are: the ventricular zone (VZ), which contains progenitor cells undergoing cell division; the intermediate zone (IZ), which can be further subdivided into the radiations (RA) and the subplate (SP); the cell-dense cortical plate ...
Hypothalamic Regulation of Sleep
Hypothalamic Regulation of Sleep

... Nambu et al. 1999). Because of the location of the hypocretin neurons in a region that has been implicated in feeding, this neuropeptide was initially thought to regulate appetite and energy metabolism (Sakurai et al. 1998). Application of hypocretin stimulates feeding (Dube et al. 1999; Sweet et al ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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