![Specific amino acids in the BAR domain allow homodimerization](http://s1.studyres.com/store/data/017818588_1-579bfb291f775f6396a98063341c4593-300x300.png)
Specific amino acids in the BAR domain allow homodimerization
... the functional versatility of the corresponding proteins, as the heterodimers may have different functions or subcellular localizations than the homodimers. However, the molecular mechanisms, which determine whether a BAR domain is able to form heterodimers, remain unknown. In order to address this ...
... the functional versatility of the corresponding proteins, as the heterodimers may have different functions or subcellular localizations than the homodimers. However, the molecular mechanisms, which determine whether a BAR domain is able to form heterodimers, remain unknown. In order to address this ...
biochemical, biophysical and electrophysiological characterisation
... The present study is focused on the production, biochemical and biophysical characterisation as well as crystallisation of the voltage-gated sodium channel from Maricaulis maris MCS10 (NaChMM). Thus, an optimised protocol for the production of milligram quantities (6 mg/L) of highly pure recombinant ...
... The present study is focused on the production, biochemical and biophysical characterisation as well as crystallisation of the voltage-gated sodium channel from Maricaulis maris MCS10 (NaChMM). Thus, an optimised protocol for the production of milligram quantities (6 mg/L) of highly pure recombinant ...
Impaired overload-induced muscle growth is associated with
... limb served as the control. Animals were kept on a water-circulation heating pad during surgery. Following each procedure, the incision was closed using stainless steel surgical clips, and animals were subcutaneously injected with ∼10 ml of warm saline as well as a one-time subcutaneous injection of ...
... limb served as the control. Animals were kept on a water-circulation heating pad during surgery. Following each procedure, the incision was closed using stainless steel surgical clips, and animals were subcutaneously injected with ∼10 ml of warm saline as well as a one-time subcutaneous injection of ...
Computational and genetic evidence that different structural
... and a large cytosolic domain located between TMH4 and 5 (Morgan et al., 2013). The BcsA/B heterodimer was co-crystallized with a putative short glucan chain bound within a central pore formed by TMH3-8 of BcsA, showing that BcsA synthesizes β-1,4 linked glucan while simultaneously transporting it ac ...
... and a large cytosolic domain located between TMH4 and 5 (Morgan et al., 2013). The BcsA/B heterodimer was co-crystallized with a putative short glucan chain bound within a central pore formed by TMH3-8 of BcsA, showing that BcsA synthesizes β-1,4 linked glucan while simultaneously transporting it ac ...
MILK - Sistem Informasi Terpadu UNIKA SOEGIJAPRANATA
... which are taken up in the blood. The composition of the organic acid mixture depends on the composition of the feed. Proteins are broken down into amino acids. The rumen flora uses these to make proteins but can also synthesize amino acids from lowmolar-mass nitrogenous components. Further on in the ...
... which are taken up in the blood. The composition of the organic acid mixture depends on the composition of the feed. Proteins are broken down into amino acids. The rumen flora uses these to make proteins but can also synthesize amino acids from lowmolar-mass nitrogenous components. Further on in the ...
the pdf - University of British Columbia
... chick spinal cord it is possible to examine developmental changes leading to the loss of regenerative ability. These findings (Nelson & Steeves, 1987; Ethell et al., 1988; Shimizu et al., 1990; Hasan et al., 1990) suggest that developmental events occur in the spinal cord around E13 leading to a los ...
... chick spinal cord it is possible to examine developmental changes leading to the loss of regenerative ability. These findings (Nelson & Steeves, 1987; Ethell et al., 1988; Shimizu et al., 1990; Hasan et al., 1990) suggest that developmental events occur in the spinal cord around E13 leading to a los ...
Selected Reaction Monitoring (SRM) to determine protein
... confirming the reduction in abundance of the encoded protein will often aid the link between genotype and phenotype. However, measuring specific protein abundance is particularly difficult in plant research where only a limited number of antibodies are available. This problem is enhanced when studyi ...
... confirming the reduction in abundance of the encoded protein will often aid the link between genotype and phenotype. However, measuring specific protein abundance is particularly difficult in plant research where only a limited number of antibodies are available. This problem is enhanced when studyi ...
PDF - SAGE Journals
... Methanococcus jannaschii is an autotrophic archaeon originally isolated from an oceanic thermal vent. The primary metabolic pathway for energy production in this hyperthermophilic microbe is methanogenesis from H2 and CO2. As an autotroph, M. jannaschii requires only CO2 as a carbon source for synth ...
... Methanococcus jannaschii is an autotrophic archaeon originally isolated from an oceanic thermal vent. The primary metabolic pathway for energy production in this hyperthermophilic microbe is methanogenesis from H2 and CO2. As an autotroph, M. jannaschii requires only CO2 as a carbon source for synth ...
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... adhesion. Recent evidence supports an important role for ROCK in the increased vasoconstriction and remodeling observed in various models of hypertension. This review will provide a commentary on the development of specific ROCK inhibitors and their clinical application. Fasudil will be discussed as ...
... adhesion. Recent evidence supports an important role for ROCK in the increased vasoconstriction and remodeling observed in various models of hypertension. This review will provide a commentary on the development of specific ROCK inhibitors and their clinical application. Fasudil will be discussed as ...
The Metamorphosis of the Aleurone Protein Storage Vacuole
... smaller protein storage vacuoles (Jones and Price, 1970). Several pieces of evidence from electron microscopy studies support this idea. First, protein storage vacuoles are not separate organelles, but are linked by tonoplast connections (Jones and Price, 1970). Second, the large vacuole formed afte ...
... smaller protein storage vacuoles (Jones and Price, 1970). Several pieces of evidence from electron microscopy studies support this idea. First, protein storage vacuoles are not separate organelles, but are linked by tonoplast connections (Jones and Price, 1970). Second, the large vacuole formed afte ...
A cap `n` collar protein isoform contains a selective Hox repressor
... 4556 N. McGinnis and others 2B). The predicted 805 amino acid CncB protein thus is distinguished from CncA by a 272 amino acid region that includes His-Pro repeats, Ala-repeats, a Pro-repeat and Val-Gly repeats, but exhibits no extended sequence similarity to other proteins in database searches bes ...
... 4556 N. McGinnis and others 2B). The predicted 805 amino acid CncB protein thus is distinguished from CncA by a 272 amino acid region that includes His-Pro repeats, Ala-repeats, a Pro-repeat and Val-Gly repeats, but exhibits no extended sequence similarity to other proteins in database searches bes ...
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... Although several PKA substrates have been described, the biological activities of these proteins are not sufficient to explain the global effect that PKA activity has on S. cerevisiae growth. In the past decade, there has been a tremendous accumulation of DNA sequence information for a wide variety ...
... Although several PKA substrates have been described, the biological activities of these proteins are not sufficient to explain the global effect that PKA activity has on S. cerevisiae growth. In the past decade, there has been a tremendous accumulation of DNA sequence information for a wide variety ...
Functional Analysis of Subunit e of the F1Fo
... Mitochondrial F1Fo-ATP synthase complexes do not exist as physically independent entities but rather form dimeric and possibly oligomeric complexes in the inner mitochondrial membrane. Stable dimerization of two F1Fo-monomeric complexes involves the physical association of two membrane-embedded Fo-s ...
... Mitochondrial F1Fo-ATP synthase complexes do not exist as physically independent entities but rather form dimeric and possibly oligomeric complexes in the inner mitochondrial membrane. Stable dimerization of two F1Fo-monomeric complexes involves the physical association of two membrane-embedded Fo-s ...
Endosomal transport of septin mRNA and protein indicates local
... therefore we underestimated the influence of microtubule-dependent transport under these conditions. ...
... therefore we underestimated the influence of microtubule-dependent transport under these conditions. ...
Translocation of Globin Fusion Proteins across the Endoplasmic
... is directed by a series of interactions between discrete sequences within the nascent chains and receptors (1). The mechanism by which this occurs has been studied by two general approaches. One approach used fractionation and reconstitution of translocation activity to identify critical components. ...
... is directed by a series of interactions between discrete sequences within the nascent chains and receptors (1). The mechanism by which this occurs has been studied by two general approaches. One approach used fractionation and reconstitution of translocation activity to identify critical components. ...
Functional analysis of the human CDC5L complex
... antibody and the protein revealed using ECL (Amersham). Lanes 1 and 2 are duplicates containing supernatants of mock immunodepletions using pre-immune IgG. Lane 3 contains the supernatant from antiCDC5L antibody immunodepleted nuclear extract and lane 4 is similar to lane 3 except that the antibody ...
... antibody and the protein revealed using ECL (Amersham). Lanes 1 and 2 are duplicates containing supernatants of mock immunodepletions using pre-immune IgG. Lane 3 contains the supernatant from antiCDC5L antibody immunodepleted nuclear extract and lane 4 is similar to lane 3 except that the antibody ...
Ribosylation of bovine serum albumin induces ROS accumulation
... et al. 2007; Bengmark 2007). Moreover, abnormal modification, including glycation, induces neuronal proteins to misfold and form amyloid fibrils in a stepwise process from prefibrils to fibrils (Necula and Kuret 2004). Glycation alters the biological activity of proteins and degradation mechanisms. ...
... et al. 2007; Bengmark 2007). Moreover, abnormal modification, including glycation, induces neuronal proteins to misfold and form amyloid fibrils in a stepwise process from prefibrils to fibrils (Necula and Kuret 2004). Glycation alters the biological activity of proteins and degradation mechanisms. ...
Overview for Electrophoresis and Western Blotting
... The discontinuous buffer systems employ different buffer ions and pH in the gel and in the electrode reservoirs. Samples are loaded onto a non-restrictive large pore gel, called a stacking gel, which overlays a smaller pore resolving gel. The major advantages of discontinuous buffer systems are that ...
... The discontinuous buffer systems employ different buffer ions and pH in the gel and in the electrode reservoirs. Samples are loaded onto a non-restrictive large pore gel, called a stacking gel, which overlays a smaller pore resolving gel. The major advantages of discontinuous buffer systems are that ...
Basic region of residues 228-231 of protein kinase CK1[alpha] is
... regulates the functioning of the Wnt signaling cascade involved in embryogenesis and carcinogenesis. b-catenin phosphorylation occurs in a multiprotein complex assembled on the scaffold protein axin. The interaction of CK1a from Danio rerio with mouse-axin has been studied using a pull-down assay th ...
... regulates the functioning of the Wnt signaling cascade involved in embryogenesis and carcinogenesis. b-catenin phosphorylation occurs in a multiprotein complex assembled on the scaffold protein axin. The interaction of CK1a from Danio rerio with mouse-axin has been studied using a pull-down assay th ...
Protein (nutrient)
Proteins are essential nutrients for the human body. They are one of the building blocks of body tissue, and can also serve as a fuel source. As a fuel, proteins contain 4 kcal per gram, just like carbohydrates and unlike lipids, which contain 9 kcal per gram. The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition.Proteins are polymer chains made of amino acids linked together by peptide bonds. During human digestion, proteins are broken down in the stomach to smaller polypeptide chains via hydrochloric acid and protease actions. This is crucial for the synthesis of the essential amino acids that cannot be biosynthesized by the body.There are nine essential amino acids which humans must obtain from their diet in order to prevent protein-energy malnutrition. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine. There are five dispensable amino acids which humans are able to synthesize in the body. These five are alanine, aspartic acid, asparagine, glutamic acid and serine. There are six conditionally essential amino acids whose synthesis can be limited under special pathophysiological conditions, such as prematurity in the infant or individuals in severe catabolic distress. These six are arginine, cysteine, glycine, glutamine, proline and tyrosine.Humans need the essential amino acids in certain ratios. Some protein sources contain amino acids in a more or less 'complete' sense. This has given rise to various ranking systems for protein sources, as described in the article.Animal sources of protein include meats, dairy products, fish and eggs. Vegan sources of protein include whole grains, pulses, legumes, soy, and nuts. Vegetarians and vegans can get enough essential amino acids by eating a variety of plant proteins. It is commonly believed that athletes should consume a higher-than-normal protein intake to maintain optimal physical performance.