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This is the accepted version of the following article:
... pathological conditions it can be abnormally phosphorylated which leads to aggregation and formation of neurofibrillary tangles representing pathological hallmark of Alzheimer's disease (AD). For its association with neurodegenerative diseases tau protein is intensively studied in various diagnostic ...
... pathological conditions it can be abnormally phosphorylated which leads to aggregation and formation of neurofibrillary tangles representing pathological hallmark of Alzheimer's disease (AD). For its association with neurodegenerative diseases tau protein is intensively studied in various diagnostic ...
this lecture as PDF here
... The nucleic acids of phages often contain unusual or modified bases. These modified bases protect phage nucleic acid from nucleases that break down host nucleic acids during phage infection. The size of the nucleic acid varies depending upon the phage. The simplest phages only have enough nucleic a ...
... The nucleic acids of phages often contain unusual or modified bases. These modified bases protect phage nucleic acid from nucleases that break down host nucleic acids during phage infection. The size of the nucleic acid varies depending upon the phage. The simplest phages only have enough nucleic a ...
pDsRed-Monomer Vector Information
... pDsRed-Monomer is primarily intended to serve as a source of DsRed-Monomer cDNA. The flanking MCS regions make it possible to excise the DsRed-Monomer coding sequence and insert it into other vector systems of choice. The vector can also be used in bacteria to produce DsRed-Monomer protein. For West ...
... pDsRed-Monomer is primarily intended to serve as a source of DsRed-Monomer cDNA. The flanking MCS regions make it possible to excise the DsRed-Monomer coding sequence and insert it into other vector systems of choice. The vector can also be used in bacteria to produce DsRed-Monomer protein. For West ...
4. Characterisation of novel proteins
... No differences of biological significance were observed between corn line 5307 and the nearisogenic line used as a comparator. A small number of statistical differences in some analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that ...
... No differences of biological significance were observed between corn line 5307 and the nearisogenic line used as a comparator. A small number of statistical differences in some analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that ...
A1060 GM Corn Line 5307 AppR SD1 Safety Assess
... No differences of biological significance were observed between corn line 5307 and the nearisogenic line used as a comparator. A small number of statistical differences in some analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that ...
... No differences of biological significance were observed between corn line 5307 and the nearisogenic line used as a comparator. A small number of statistical differences in some analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that ...
Possibilities and Limitations of Genetic Engineering
... sunflower seed albumin in alfalfa leaves (Tabe, 1995). Maize gamma zein, which codes for a sulfur amino acid-rich seed storage protein, has also been introduced into alfalfa in order to improve its nutritional quality for wool production (Bellucci et al., 1997; Bellucci et al., 2001). Lignin is the ...
... sunflower seed albumin in alfalfa leaves (Tabe, 1995). Maize gamma zein, which codes for a sulfur amino acid-rich seed storage protein, has also been introduced into alfalfa in order to improve its nutritional quality for wool production (Bellucci et al., 1997; Bellucci et al., 2001). Lignin is the ...
Cloning and characterization of an eukaryotic initiation factor
... together with pCoHYGRO containing Escherichia coli hygromycin B-phosphotransferase gene under control of the Drosophila copia promoter (Invitrogen). Transfected cells were selected with hygromycin (300 Ag/ml) for 6 weeks. Expression was induced in cells by addition of CuSO4 to the culture media at a ...
... together with pCoHYGRO containing Escherichia coli hygromycin B-phosphotransferase gene under control of the Drosophila copia promoter (Invitrogen). Transfected cells were selected with hygromycin (300 Ag/ml) for 6 weeks. Expression was induced in cells by addition of CuSO4 to the culture media at a ...
Quantitative RT-PCR Platform to Measure Transcript Levels of C and
... variability of their signal intensity was verified through 1,532 available bread wheat 55k microarrays in ...
... variability of their signal intensity was verified through 1,532 available bread wheat 55k microarrays in ...
Evolution of hard proteins in the sauropsid integument in relation to
... Fig. 1 Macroscopic aspect of reptilian scales (A–D) and histology of the epidermis in scales of different reptiles (E–M). (A) Overlapped trunk scale of snake (Natrix natrix). Bar, 0.5 mm. (B) Little overlapping scale of ventral region of midtrunk region of the tuatara (Sphenodon punctatus). Bar, 0.5 ...
... Fig. 1 Macroscopic aspect of reptilian scales (A–D) and histology of the epidermis in scales of different reptiles (E–M). (A) Overlapped trunk scale of snake (Natrix natrix). Bar, 0.5 mm. (B) Little overlapping scale of ventral region of midtrunk region of the tuatara (Sphenodon punctatus). Bar, 0.5 ...
Transcriptome and metabolite profiling the infection cycle of
... investigated both pathogen and host at two time points during the initial symptomless interaction (4- and 10-dpi) and at the onset of first symptoms (the transitional phase) which occurred at 13-dpi in these experiments. This study confirmed many previously published fungal transcriptional responses ...
... investigated both pathogen and host at two time points during the initial symptomless interaction (4- and 10-dpi) and at the onset of first symptoms (the transitional phase) which occurred at 13-dpi in these experiments. This study confirmed many previously published fungal transcriptional responses ...
Inhibition of the Particle-associated RNA
... every test as a standard reference compound. For accurate quantitative comparisons, various compounds were tested in parallel in the same experiment using a single virus preparation. Unless otherwise stated, inhibitory compounds at a range of different concentrations from o-I to o.ooi mM were added ...
... every test as a standard reference compound. For accurate quantitative comparisons, various compounds were tested in parallel in the same experiment using a single virus preparation. Unless otherwise stated, inhibitory compounds at a range of different concentrations from o-I to o.ooi mM were added ...
molecular phylogeny of the haplosporidia based on
... groups to the relative inclusion and exclusion of potentially phylogenetically informative sites. In the first series of analyses, which concerned the relative position of Haplosporidia within Eukaryota, it was noted that there were large inserted regions in the SSU rDNA sequences of some taxa, incl ...
... groups to the relative inclusion and exclusion of potentially phylogenetically informative sites. In the first series of analyses, which concerned the relative position of Haplosporidia within Eukaryota, it was noted that there were large inserted regions in the SSU rDNA sequences of some taxa, incl ...
Variations in amino acid composition in bacterial single stranded
... role. It interacts and modulates the activity of various proteins involved in all aspects of DNA metabolism. EcoSSB has become one of the standard models for studying ssDNA-SSB interactions, a comprehensive review of which can be found in the work of Shereda and co-authors (5). The crystal structure ...
... role. It interacts and modulates the activity of various proteins involved in all aspects of DNA metabolism. EcoSSB has become one of the standard models for studying ssDNA-SSB interactions, a comprehensive review of which can be found in the work of Shereda and co-authors (5). The crystal structure ...
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... quorum sensing systems, las and rhl. These systems control the transcription of genes in response to population density through the intercellular signals N-(3oxododecanoyl)-L-homoserine lactone (3-oxo-C12-HSL) and N-(butanoyl)-Lhomoserine lactone (C4-HSL). Also plays a significant role in the transc ...
... quorum sensing systems, las and rhl. These systems control the transcription of genes in response to population density through the intercellular signals N-(3oxododecanoyl)-L-homoserine lactone (3-oxo-C12-HSL) and N-(butanoyl)-Lhomoserine lactone (C4-HSL). Also plays a significant role in the transc ...
Slide 1
... and analysis of rare mRNA transcripts or other RNA present in low abundance. RNA cannot serve as a template for PCR, so it must be first transcribed into cDNA with reverse transcriptase from Moloney murine leukemia virus or Avian myeloblastosis virus, and the cDNA copy is then amplified. ...
... and analysis of rare mRNA transcripts or other RNA present in low abundance. RNA cannot serve as a template for PCR, so it must be first transcribed into cDNA with reverse transcriptase from Moloney murine leukemia virus or Avian myeloblastosis virus, and the cDNA copy is then amplified. ...
Membrane protein integration into the endoplasmic reticulum
... Introduction Helical integral membrane proteins have essential roles in the cell, and account for almost one-fourth of all proteins in most organisms [1]. However, our understanding of their biosynthesis and folding lags far behind our understanding of water-soluble proteins. The targeting and inser ...
... Introduction Helical integral membrane proteins have essential roles in the cell, and account for almost one-fourth of all proteins in most organisms [1]. However, our understanding of their biosynthesis and folding lags far behind our understanding of water-soluble proteins. The targeting and inser ...
Polypeptide Composition of Envelopes of Spinach Chloroplasts
... Preparation of intact chloroplasts—Spinach was purchased from a local farmer. Intact chloroplasts were prepared according to Siegenthaler and Dumont (1990) with some modifications. Leaves were homogenized for 10 s in the grinding medium containing 350 mM sorbitol, 25 mM 3-(/V-morpholino)propanesufon ...
... Preparation of intact chloroplasts—Spinach was purchased from a local farmer. Intact chloroplasts were prepared according to Siegenthaler and Dumont (1990) with some modifications. Leaves were homogenized for 10 s in the grinding medium containing 350 mM sorbitol, 25 mM 3-(/V-morpholino)propanesufon ...
Dietary protein for athletes - Inside Outside Wellness Center
... resistance and (or) endurance exercise require more protein than their sedentary counterparts. The RDA values for protein are clearly set at ‘‘. . .the level of protein judged to be adequate... to meet the known nutrient needs for practically all healthy people. . .’’. The RDA covers protein losses ...
... resistance and (or) endurance exercise require more protein than their sedentary counterparts. The RDA values for protein are clearly set at ‘‘. . .the level of protein judged to be adequate... to meet the known nutrient needs for practically all healthy people. . .’’. The RDA covers protein losses ...
The monocarboxylate transporter family
... affinities. They are part of the larger SLC16 family of solute carriers, also known as the MCT family, which has 14 members in total, all sharing conserved sequence motifs. The family includes a high-affinity thyroid hormone transporter (MCT8), an aromatic amino acid transporter (T-type amino acid tra ...
... affinities. They are part of the larger SLC16 family of solute carriers, also known as the MCT family, which has 14 members in total, all sharing conserved sequence motifs. The family includes a high-affinity thyroid hormone transporter (MCT8), an aromatic amino acid transporter (T-type amino acid tra ...
FASTA is a program for database searching by homology. FASTA
... and any sequence in a database. Each sequence is broken down into short words a few sequence characters long and these words are organized into a table indicating where they are in the sequence. If one or more words are present in both sequences, and especially if several words can be joined, the se ...
... and any sequence in a database. Each sequence is broken down into short words a few sequence characters long and these words are organized into a table indicating where they are in the sequence. If one or more words are present in both sequences, and especially if several words can be joined, the se ...
9.1 Amino Acids—A Second Look, Continued
... Proteins are classified into groups based on their three-dimensional shape. • Globular proteins are compact, spherical structures that are soluble in an aqueous environment. Myoglobin, which stores oxygen in muscle, is an example. • Fibrous proteins are long, threadlike structures that have high hel ...
... Proteins are classified into groups based on their three-dimensional shape. • Globular proteins are compact, spherical structures that are soluble in an aqueous environment. Myoglobin, which stores oxygen in muscle, is an example. • Fibrous proteins are long, threadlike structures that have high hel ...
... c) Regulation of glycogen levels. b) Regulation of glycolysis d) Regulation of mRNA synthesis. 1. Allosteric effects refer to the fact that a protein/enzyme has two structures. 2. One structure is “active” (R-state) the other structure is “inactive” (T-state). 3. The two states are in equilibrium wi ...
Preparation of Translationally Competent tRNA by Direct Chemical
... with the ability to perform precise structure-function studies with proteins, beyond that which can be performed with the 20 natural amino acids.1-3 This is usually achieved through nonsense suppression, in which the site of interest is mutated to a stop codon, and an aminoacyl-tRNA bearing the appr ...
... with the ability to perform precise structure-function studies with proteins, beyond that which can be performed with the 20 natural amino acids.1-3 This is usually achieved through nonsense suppression, in which the site of interest is mutated to a stop codon, and an aminoacyl-tRNA bearing the appr ...
Experimental Analysis of the Rice Mitochondrial
... mitochondria isolated by Suc gradient centrifugation and gel-based spot analysis. However, there is less than 20% overlap between the protein lists reported in these two studies. The removal of contaminants is essential for accurate curation of subcellular organelle proteomes. While dual targeting o ...
... mitochondria isolated by Suc gradient centrifugation and gel-based spot analysis. However, there is less than 20% overlap between the protein lists reported in these two studies. The removal of contaminants is essential for accurate curation of subcellular organelle proteomes. While dual targeting o ...
The deleterious effect of missense mutations on pre
... ABSTRACT The presence of missense mutations detected during genetic testing makes it difficult to classify their pathogenic effect. It is possible that the predicted amino acid change affects protein function; however, it is also possible that a missense mutation does not act at the protein level b ...
... ABSTRACT The presence of missense mutations detected during genetic testing makes it difficult to classify their pathogenic effect. It is possible that the predicted amino acid change affects protein function; however, it is also possible that a missense mutation does not act at the protein level b ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.