• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Supplementary Information (doc 7548K)
Supplementary Information (doc 7548K)

... that was heterozygous by exome sequencing (minimum coverage of 10 reads with >3 reads for each allele) showed 80% usage of a single allele. Patient samples where GATA2 gene expression was too low to assess allelic usage or where only homozygous SNPs were present were reported as non-informative (NI ...
bio_ch03-2
bio_ch03-2

... processing proteins. (continued) • Ribosomes link amino acids to form proteins. • Golgi Apparatus processes, sorts and delivers proteins. • Vesicles are membrane-bound sacs that separate material from cytoplasm….transports protein to Golgi App. ...
Antibody structure : the early studies
Antibody structure : the early studies

... together, the point of joining does not always need to be the same. In this way, the nucleotide triplet which encodes one a.a. may be different each time the same V and J segments are joined. • Similarly in H chains, additional variability occurs at the D-J and V-D-J joining points. • In addition to ...
Cell Size Limitations
Cell Size Limitations

... Normal Control of the Cell Cycle • This uncontrolled dividing of cells can result from the failure to produce certain enzymes, the overproduction of enzymes, or the production of other enzymes at the wrong time. • Cancer is a malignant growth resulting from uncontrolled cell division. ...
Chapter 3: Presentation Slides
Chapter 3: Presentation Slides

... • Many human genes are on the Xchromosome = X-linked • Males have XY genotype and only one copy of X-linked genes • Mutations = genetic changes in X-linked genes will be expressed phenotypically in males even if recessive = X-linked genetic disorder • Hemophilia A =X-linked disorder ...
Supplementary Figure Legend
Supplementary Figure Legend

... of the ATG translation initiation codon in the reference cDNA sequence (accession number U39817) and the initiation codon is amino acid residue 1 in the protein sequence. The two mutations present in each cell line are indicated, and the putative effects on the gene products are shown in Tables 1 an ...
TAN Huarong
TAN Huarong

... fold higher than that of wild-type strain. The sanJ gene was inactivated by the insertion of kanamycin resistance gene and the resulting disruption mutants failed to produce nikkomycins. Moreover, the nikkomycin production was recovered by cis-complementation with a single copy of sanJ. The result i ...
Angiosperms VII
Angiosperms VII

... large amounts of auxin (IAA) which is transported to the stem – This inhibits abscission of leaves and fruits – Environmental or age changes stimulate production of ethylene which stimulates production of abscission zone forming ...
Illumina Infinium HumanMethylation450 BeadChip Data
Illumina Infinium HumanMethylation450 BeadChip Data

... powerful embedded statistics and visualizations to yield deep biological interpretation. Going from raw data to biological interpretation has never been easier. ...
Imprinting evolution and the price of silence
Imprinting evolution and the price of silence

... a number of factors including histone methylation, histone acetylation and cytosine methylation. Cytosine methylation is a vital DNA modification(3) that is important for the regulation of many aspects of cellular function including imprinting.(4,5) The 5-carbon position of cytosines in the context ...
Deletion Map of Chromosome 9 and p16 (CDKN2A) Gene Alterations
Deletion Map of Chromosome 9 and p16 (CDKN2A) Gene Alterations

... Recent molecular studies have revealed that the genesis and pro gression of human cancer is largely attributed to accumulation of a series of genetic events that culminate in the transformation of a cell into a malignant clone (1). Central to this theory are the roles of oncogenes and tumor suppress ...
Reversing Chromatin Accessibility Differences that Distinguish
Reversing Chromatin Accessibility Differences that Distinguish

... metaphase is driven by mitotic-specific condensation factors [1, 2]. Broadly speaking, this is thought to include histone proteins undergoing post translational modifications and interaction of histone tails with neighboring nucleosomes [1]. This is complemented with a network of non-histone protein ...
Gene Section HDAC2 (histone deacetylase 2) Atlas of Genetics and Cytogenetics
Gene Section HDAC2 (histone deacetylase 2) Atlas of Genetics and Cytogenetics

... to be recruited by transcription factors such as YY1, SP1/SP3, the tumor suppressor genes p53 and BRCA1. HDAC2 can also be tethered to DNA as a part of the multiprotein corepressor complexes CoREST, mSin3 and NuRD. These complexes are targeted to specific genomic sequences by interactions with seque ...
Rhom-2 Expression Does Not Always Correlate With
Rhom-2 Expression Does Not Always Correlate With

... ern blot was prepared using BamHI-digested DNA. Hybridization of the Southern blot with a TCR-p probez4is shown in Fig 1A. As controls, DNAs from the KB and HPB cell lines were included. A germline band of 23 kb and two smaller rearranged bands for the TCR-p gene were observed for the Kl3 and HPB ce ...
view pdf - University of Arizona
view pdf - University of Arizona

... antipodal cells (six genes), whereas the remaining seven genes were expressed in two (four genes) or more (three genes) cell types, usually with one cell type showing a higher level of expression. The expression of a subset of these genes was also analysed during megagametogenesis and early seed dev ...
Identification of genes expressed in the angiosperm female
Identification of genes expressed in the angiosperm female

... antipodal cells (six genes), whereas the remaining seven genes were expressed in two (four genes) or more (three genes) cell types, usually with one cell type showing a higher level of expression. The expression of a subset of these genes was also analysed during megagametogenesis and early seed dev ...
scylla and charybde, homologues of the human apoptotic gene
scylla and charybde, homologues of the human apoptotic gene

... products represent the prototypes for a new family of proteins. These related genes code for pioneer proteins, and their deduced polypeptide sequences are most notable for excluding, rather than suggesting, protein function. Although the biochemical mechanism of the RTP801, Scylla and Charybde prote ...
THE INTERRELATIONSHIP OF CELL GROWTH AND
THE INTERRELATIONSHIP OF CELL GROWTH AND

... The coordination of cell growth and division has been examined in isoaenic hanloid and dioioid strains of Saccharomyccs cerevisiae. The average cell volume of the haploid and diploid ‘cells was unaffected by a range of environmental conditions and generation times. For most environments and generati ...
Page | 244 - FTHS Wiki
Page | 244 - FTHS Wiki

... Analysis Questions (continued): 3. Bryophytes are a phylum of the plant kingdom that lacks a vascular system. They have no specialized tubes for transporting water and organic products of photosynthesis. Instead, they rely upon diffusion. Examples of bryophytes are the mosses. Explain why mosses can ...
Discovery of MLL1 binding units, their localization to CpG Islands
Discovery of MLL1 binding units, their localization to CpG Islands

... interphase stage of cell-cycle [31]. However, how MLL1 bookmarks genes to maintain transcriptional memory has not been addressed. The finding that gene-bookmarking by MLL1 is largely independent of the methylation status of H3K4 on mitotic chromosomes [31] provokes the question of whether interactio ...
Neutral Competition for Drosophila Follicle and Cyst Stem Cell
Neutral Competition for Drosophila Follicle and Cyst Stem Cell

... multiple time points after clone induction. FRT recombination produces wildtype or homozygous mutant clones that are marked, in this case, by the lack of GFP expression (GFP–), and FSC clones can be identified as large contiguous groups of marked cells that extend from the Region 2a/2b border throug ...
Brooker Chapter 23
Brooker Chapter 23

... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Leukaemia Section t(14;18)(q32;q21) t(2;18)(p11;q21) t(18;22)(q21;q11)
Leukaemia Section t(14;18)(q32;q21) t(2;18)(p11;q21) t(18;22)(q21;q11)

... Clinics and pathology ...
application of stem cell - Website Staff UI
application of stem cell - Website Staff UI

... Intravenous injection of mesenchymal stem cells MSC isolated from bone marrow into the brain of 30 patient with cerebrovascular diseases increased the function of the brain according to the Barthel Index and ...
Chapter 15 Section 2: Gene Technologies in Our Lives
Chapter 15 Section 2: Gene Technologies in Our Lives

... Proteomics (PROH tee OHM iks): ...
< 1 ... 33 34 35 36 37 38 39 40 41 ... 174 >

Epigenetics in stem-cell differentiation

Embryonic stem cells are capable of self-renewing and differentiating to the desired fate depending on its position within the body. Stem cell homeostasis is maintained through epigenetic mechanisms that are highly dynamic in regulating the chromatin structure as well as specific gene transcription programs. Epigenetics has been used to refer to changes in gene expression, which are heritable through modifications not affecting the DNA sequence.The mammalian epigenome undergoes global remodeling during early stem cell development that requires commitment of cells to be restricted to the desired lineage. There has been multiple evidence suggesting that the maintenance of the lineage commitment of stem cells are controlled by epigenetic mechanisms such as DNA methylation, histone modifications and regulation of ATP-dependent remolding of chromatin structure. Based on the histone code hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell.This regulation of chromatin through epigenetic modifications is a molecular mechanism that will determine whether the cell will continue to differentiate into the desired fate. A research study performed by Lee et al. examined the effects of epigenetic modifications on the chromatin structure and the modulation of these epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) cells.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report