From mutation to gene
... infected plants. Plasmid vectors based on the TI plasmid are widely used in plant molecular biology. Transfer of a cloned DNA into Arabadopsis can be done by inverting a potted plant into a suspension of Agrobacterium containing a plasmid with the desired DNA. [XX Talk to arabadopsis students about ...
... infected plants. Plasmid vectors based on the TI plasmid are widely used in plant molecular biology. Transfer of a cloned DNA into Arabadopsis can be done by inverting a potted plant into a suspension of Agrobacterium containing a plasmid with the desired DNA. [XX Talk to arabadopsis students about ...
Synthetic Zinc Finger Transcription Factor Action at
... There is general agreement that the nucleosome can impede recognition of specific promoter elements by TFIIIA (15, 17–26) and that modification of histone-DNA interactions through nucleosome repositioning (18, 19), histone depletion (20, 21), and removal of the histone tails (22, 23) can promote TFI ...
... There is general agreement that the nucleosome can impede recognition of specific promoter elements by TFIIIA (15, 17–26) and that modification of histone-DNA interactions through nucleosome repositioning (18, 19), histone depletion (20, 21), and removal of the histone tails (22, 23) can promote TFI ...
Leukaemia Section t(6;14)(p21;q32) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... G-banding - Top: Courtesy Jean Luc Lai; Bottom: Courtesy Melanie Zenger and Claudia Haferlach. ...
... G-banding - Top: Courtesy Jean Luc Lai; Bottom: Courtesy Melanie Zenger and Claudia Haferlach. ...
- Wiley Online Library
... interacting partner [18]. c-Myc is an oncogene encoding a transcription factor that is important for stem cell maintenance [19] and induced pluripotency [20]. Third, Zfp281 has been identified and validated as a top candidate target of the skin microRNA203, which promotes differentiation and represse ...
... interacting partner [18]. c-Myc is an oncogene encoding a transcription factor that is important for stem cell maintenance [19] and induced pluripotency [20]. Third, Zfp281 has been identified and validated as a top candidate target of the skin microRNA203, which promotes differentiation and represse ...
The epigenetic basis of gender in flowering plants and mammals
... paternal expression is lost in PWS, and maternal expression in AS (Ref. 19). Therefore, maternalization and paternalization of this chromosomal region cause distinct disease phenotypes. Strikingly, abnormal biallelic expression of imprinted growth promoters, or deletion of imprinted genes involved i ...
... paternal expression is lost in PWS, and maternal expression in AS (Ref. 19). Therefore, maternalization and paternalization of this chromosomal region cause distinct disease phenotypes. Strikingly, abnormal biallelic expression of imprinted growth promoters, or deletion of imprinted genes involved i ...
Development of the Kidneys
... Park (2012) used Ch-IP/seq and transcription profiling to show that Six2 and Wnt (via b-catenin & Tcf/Lef) regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Some genes activated by one are repressed by the other while other genes require both Six2 a ...
... Park (2012) used Ch-IP/seq and transcription profiling to show that Six2 and Wnt (via b-catenin & Tcf/Lef) regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Some genes activated by one are repressed by the other while other genes require both Six2 a ...
Formation of synovial joints and articular cartilage
... neutral environment, but not in non-neutral environment. It occurs in the embryo once skeletogenic mesenchymal cells have condensed into precartilaginous masses. Most cells in these masses commit to the growth plate chondrocyte fate, while specific subpopulations commit to the articular fate and go ...
... neutral environment, but not in non-neutral environment. It occurs in the embryo once skeletogenic mesenchymal cells have condensed into precartilaginous masses. Most cells in these masses commit to the growth plate chondrocyte fate, while specific subpopulations commit to the articular fate and go ...
development, the Linker histone H1 is essential for Drosophila
... expression of H1-specific dsRNA is driven by the GAL4-responsive UAS promoter. (Open triangle) UAS promoter; (black arrows) H1 cDNA fragments; (dark-gray box) act5C intron; (open circle) SV40 polyadenylation site; (light arrow) white gene; (small black arrowheads) P-element sequences. (B) The expres ...
... expression of H1-specific dsRNA is driven by the GAL4-responsive UAS promoter. (Open triangle) UAS promoter; (black arrows) H1 cDNA fragments; (dark-gray box) act5C intron; (open circle) SV40 polyadenylation site; (light arrow) white gene; (small black arrowheads) P-element sequences. (B) The expres ...
The constitution and the control of the ovarian
... nests leads to massive apoptosis and formation of primordial follicles containing germ cells arrested at the diplotene stage. One main factor involved in ultimate stage of ovarian follicle formation is FIGLA, a germ cell-specific bHLH transcription factor (Fig. 1). Female mice lacking Figla are ster ...
... nests leads to massive apoptosis and formation of primordial follicles containing germ cells arrested at the diplotene stage. One main factor involved in ultimate stage of ovarian follicle formation is FIGLA, a germ cell-specific bHLH transcription factor (Fig. 1). Female mice lacking Figla are ster ...
Slide 1
... ChE 170: Engineering Cell Biology – Control of gene expression, manipulating genes 11/03/11 ...
... ChE 170: Engineering Cell Biology – Control of gene expression, manipulating genes 11/03/11 ...
Lecture 8 - Instructional Web Server
... or motivation, the methods, result s and conc lusions. It is often easier to complete the abstract after the rest of the paper is complete and all of the results are in place, but you shou ld still try to create a rough draft of the abstract at the beginning. When your abstract is finis hed, use the ...
... or motivation, the methods, result s and conc lusions. It is often easier to complete the abstract after the rest of the paper is complete and all of the results are in place, but you shou ld still try to create a rough draft of the abstract at the beginning. When your abstract is finis hed, use the ...
Assembly of additional heterochromatin distinct from centromere
... artificial chromosomes (HAC) with functional centromeres that depend on type I alphoid arrays composed of highly homogenous higher-order repeating units (Harrington et al., 1997; Ikeno et al., 1998; Masumoto et al., 1998; Henning et al., 1999; Ebersole et al., 2000; Mejia et al., 2001; Grimes et al. ...
... artificial chromosomes (HAC) with functional centromeres that depend on type I alphoid arrays composed of highly homogenous higher-order repeating units (Harrington et al., 1997; Ikeno et al., 1998; Masumoto et al., 1998; Henning et al., 1999; Ebersole et al., 2000; Mejia et al., 2001; Grimes et al. ...
Online Repository - Nederlands Tweelingen Register
... containing eQTLs in tissues relevant for other diseases or traits are also available but were not analysed in this study. Step 2: calculate a gene-based association statistic Q for each gene based on results from individual SNPs in a GWAS of interest. The 1-df disease association chi-square statisti ...
... containing eQTLs in tissues relevant for other diseases or traits are also available but were not analysed in this study. Step 2: calculate a gene-based association statistic Q for each gene based on results from individual SNPs in a GWAS of interest. The 1-df disease association chi-square statisti ...
Human cytomegalovirus mediates cell cycle progression through G1
... form, Rb binds and inactivates the cellular transcription factor E2F. As E2F activates expression of a number of S phase genes, Rb plays a major role in repressing gene expression associated with the S phase of the cell cycle. Induction of cell cycle progression by E1A is believed, in part, to be du ...
... form, Rb binds and inactivates the cellular transcription factor E2F. As E2F activates expression of a number of S phase genes, Rb plays a major role in repressing gene expression associated with the S phase of the cell cycle. Induction of cell cycle progression by E1A is believed, in part, to be du ...
3283 Proper chromatin condensation and sister chromatid
... Based on a sequence alignment of SMC2 proteins, we designed degenerate oligonucleotide primers to amplify an Arabidopsis genomic fragment encoding the conserved amino terminal nucleotide-binding domain. Sequencing of this fragment and computer analysis confirmed its identity as an SMC2 gene fragment ...
... Based on a sequence alignment of SMC2 proteins, we designed degenerate oligonucleotide primers to amplify an Arabidopsis genomic fragment encoding the conserved amino terminal nucleotide-binding domain. Sequencing of this fragment and computer analysis confirmed its identity as an SMC2 gene fragment ...
Molecular studies of major depressive disorder
... Association studies of a priori candidate genes in MDD research have primarily focussed on genes involved in the serotoninergic system. The rationale behind this approach is that considerable evidence implicates dysregulation of this system as being pivotal in the development of depression. Of parti ...
... Association studies of a priori candidate genes in MDD research have primarily focussed on genes involved in the serotoninergic system. The rationale behind this approach is that considerable evidence implicates dysregulation of this system as being pivotal in the development of depression. Of parti ...
Quantitative analysis of NOR expression in a B chromosome of the
... the so-called primary NORs, which are the only active NORs detected in Spanish populations, and the small clusters contain secondary NORs which are usually inactive in Spanish populations (López-León et al. 1995b), but are sometimes active in Moroccan populations (Bakkali et al. 2001). The rRNA gene ...
... the so-called primary NORs, which are the only active NORs detected in Spanish populations, and the small clusters contain secondary NORs which are usually inactive in Spanish populations (López-León et al. 1995b), but are sometimes active in Moroccan populations (Bakkali et al. 2001). The rRNA gene ...
Chapter 14: Cell Reproduction
... – 2. Certain critical processes (DNA replication, chromosome alignment) have not been properly completed ...
... – 2. Certain critical processes (DNA replication, chromosome alignment) have not been properly completed ...
Leukaemia Section t(3;7)(q26;q21) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... the fusion gene AML1 / MDS1 /EVI1 in CML-BC, or MDS or as part of the fusion gene ETV6 /MDS1/EVI1 in AML with t(3;12) translocation. EVI1 is also involved in other translocations such as t(2;3)(p13;q26), t(2;3)(q23;q26), t(3;17)(q26;q22) and t(3;13)(q26;q13-14). Other studies have reported abnormal ...
... the fusion gene AML1 / MDS1 /EVI1 in CML-BC, or MDS or as part of the fusion gene ETV6 /MDS1/EVI1 in AML with t(3;12) translocation. EVI1 is also involved in other translocations such as t(2;3)(p13;q26), t(2;3)(q23;q26), t(3;17)(q26;q22) and t(3;13)(q26;q13-14). Other studies have reported abnormal ...
Parental Legacy Determines Methylation and Expression of an
... referred to as methylated, was observed in all carrier offspring of female carriers mated with noncarrier males. It consisted of a 12 kb fragment and less intense 8 and 2.4 kb fragments (Figure 4, lane 2). A second pattern, referred to as undermethylated, was observed in all carrier offspring of car ...
... referred to as methylated, was observed in all carrier offspring of female carriers mated with noncarrier males. It consisted of a 12 kb fragment and less intense 8 and 2.4 kb fragments (Figure 4, lane 2). A second pattern, referred to as undermethylated, was observed in all carrier offspring of car ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... traits and disease, much attention has been drawn recently to these epigenetic mechanisms; non-DNA sequence-based regulation of gene expression by DNA methylation, histone modification, microRNAs etc 5. DNA methylation is one of the most extensively studied epigenetic mechanisms in human populations ...
... traits and disease, much attention has been drawn recently to these epigenetic mechanisms; non-DNA sequence-based regulation of gene expression by DNA methylation, histone modification, microRNAs etc 5. DNA methylation is one of the most extensively studied epigenetic mechanisms in human populations ...
PDF
... The process of generating differentiated cell types performing specific effector functions from their respective undifferentiated precursors is dictated by extracellular signals, which alter the host cell’s capacity to perform cellular functions. One major mechanism for bringing about such changes i ...
... The process of generating differentiated cell types performing specific effector functions from their respective undifferentiated precursors is dictated by extracellular signals, which alter the host cell’s capacity to perform cellular functions. One major mechanism for bringing about such changes i ...
Midterm Exam
... d. Peripheral giant cell granuloma e. More than one of the above 23. Kaposi sarcoma is associated with (or is caused by?) human herpesvirus 8 (HHV 8). This statement is: a. True b. False 26. Osseous choristoma is a benign neoplasm of long bones. This statement is: a. True b. False 27. Which of the ...
... d. Peripheral giant cell granuloma e. More than one of the above 23. Kaposi sarcoma is associated with (or is caused by?) human herpesvirus 8 (HHV 8). This statement is: a. True b. False 26. Osseous choristoma is a benign neoplasm of long bones. This statement is: a. True b. False 27. Which of the ...
A reliable and efficient method for deleting
... to study the importance of this cis-acting regulatory element in renin gene regulation. To build a targeting construct for homologous recombination, we used a vector that contains three appropriately placed Chi-sites on either side of the cloning cassette. Chi-sites stimulate a 50-fold higher recomb ...
... to study the importance of this cis-acting regulatory element in renin gene regulation. To build a targeting construct for homologous recombination, we used a vector that contains three appropriately placed Chi-sites on either side of the cloning cassette. Chi-sites stimulate a 50-fold higher recomb ...