Control of neural stem cell self-renewal and differentiation in
... and central brain, neuroblasts first arise by delamination from the neuroectoderm during embryonic development (Fig. 1A). In the embryonic neuroectoderm, groups of cells are singled out as proneural clusters through the expression of genes of the achaete-scute complex and daughterless. In these clus ...
... and central brain, neuroblasts first arise by delamination from the neuroectoderm during embryonic development (Fig. 1A). In the embryonic neuroectoderm, groups of cells are singled out as proneural clusters through the expression of genes of the achaete-scute complex and daughterless. In these clus ...
Coordinated repression and activation of two
... inappropriately express the neuronal protein Futsch (Hummel et al., 2000), the antigen of the 22C10 antibody (Zipursky et al., 1984), in somatic and visceral muscles (Giesen et al., 1997; Murawsky et al., 2001). We confirmed this observation and, in addition, found that Futsch is also misexpressed i ...
... inappropriately express the neuronal protein Futsch (Hummel et al., 2000), the antigen of the 22C10 antibody (Zipursky et al., 1984), in somatic and visceral muscles (Giesen et al., 1997; Murawsky et al., 2001). We confirmed this observation and, in addition, found that Futsch is also misexpressed i ...
Learning About DNA
... Griffith then used mice to conduct an experiment to test this question. He removed the protein capsule and injected mice with only the DNA; the mice died. He also discovered the one strain, smooth (S), was deadly while the other strain, rough (R), was harmless. He heated the (S) bacteria and found i ...
... Griffith then used mice to conduct an experiment to test this question. He removed the protein capsule and injected mice with only the DNA; the mice died. He also discovered the one strain, smooth (S), was deadly while the other strain, rough (R), was harmless. He heated the (S) bacteria and found i ...
concepts-of-biology
... Cytokinesis is the second part of the mitotic phase during which cell division is completed by the physical separation of the cytoplasmic components into two daughter cells. Although the stages of mitosis are similar for most eukaryotes, the process of cytokinesis is quite different for eukaryotes t ...
... Cytokinesis is the second part of the mitotic phase during which cell division is completed by the physical separation of the cytoplasmic components into two daughter cells. Although the stages of mitosis are similar for most eukaryotes, the process of cytokinesis is quite different for eukaryotes t ...
Developmental Genetics
... oped debilitating diseases as they matured (Humphreys et al. 2001; Jaenisch and Wilmut 2001; Kolata 2001). As we will shortly see, this problem is due in large part to the differences in methylation between the chromatin of the zygote and the differentiated cell. Second, the phenotype of the cloned ...
... oped debilitating diseases as they matured (Humphreys et al. 2001; Jaenisch and Wilmut 2001; Kolata 2001). As we will shortly see, this problem is due in large part to the differences in methylation between the chromatin of the zygote and the differentiated cell. Second, the phenotype of the cloned ...
list of publications
... governed by complex DNA-regions, called cis-regulators. Cis-regulators are and recent findings indicate the existence of a complex epigenetic maintenance activated in a sequential order along the anterior-posterior axis in the early system conserved in eukaryots which is responsible for the maintena ...
... governed by complex DNA-regions, called cis-regulators. Cis-regulators are and recent findings indicate the existence of a complex epigenetic maintenance activated in a sequential order along the anterior-posterior axis in the early system conserved in eukaryots which is responsible for the maintena ...
Using food and controlling growth - Delivery guide
... The majority of learners have difficulty when studying mitosis and meiosis due to a lack of understanding about when the chromosomes replicate. An effort should be made to highlight that the quantity of DNA has doubled even before mitosis begins. Learners are likely to have little understanding of s ...
... The majority of learners have difficulty when studying mitosis and meiosis due to a lack of understanding about when the chromosomes replicate. An effort should be made to highlight that the quantity of DNA has doubled even before mitosis begins. Learners are likely to have little understanding of s ...
Transcriptional Repression of Hox Genes by C. elegans HP1/HPL
... Linker histone (H1) and heterochromatin protein 1 (HP1) play central roles in the formation of higher-order chromatin structure and gene expression. Recent studies have shown a physical interaction between H1 and HP1; however, the biological role of histone H1 and HP1 is not well understood. Additio ...
... Linker histone (H1) and heterochromatin protein 1 (HP1) play central roles in the formation of higher-order chromatin structure and gene expression. Recent studies have shown a physical interaction between H1 and HP1; however, the biological role of histone H1 and HP1 is not well understood. Additio ...
6 | REPRODUCTION AT THE CELLULAR LEVEL
... Cytokinesis is the second part of the mitotic phase during which cell division is completed by the physical separation of the cytoplasmic components into two daughter cells. Although the stages of mitosis are similar for most eukaryotes, the process of cytokinesis is quite different for eukaryotes t ...
... Cytokinesis is the second part of the mitotic phase during which cell division is completed by the physical separation of the cytoplasmic components into two daughter cells. Although the stages of mitosis are similar for most eukaryotes, the process of cytokinesis is quite different for eukaryotes t ...
Seed specific polycomb group gene and methods of use for same
... 3(A): Late globular Wild type embryo. 3(B): Late globular mea embryo. 3(C): Mid-globular Wild type embryo. 3(D): Mid-globular mea embryo. 3(E): Early heart stage Wild type embryo. 3(F): Early heart stage mea embryo. ...
... 3(A): Late globular Wild type embryo. 3(B): Late globular mea embryo. 3(C): Mid-globular Wild type embryo. 3(D): Mid-globular mea embryo. 3(E): Early heart stage Wild type embryo. 3(F): Early heart stage mea embryo. ...
Tools for genetic analysis in Trypanosoma brucei unlinked fields
... pLEW20 is the prototypical regulated single-promoter (GPEETp) expression vector. In the prototypical pLEW100 dual-promoter vector, a T7 promoter drives the selectable marker and TetR-regulated GPEET promoter drives the gene of interest (incidentally, there do not appear to be any significant differe ...
... pLEW20 is the prototypical regulated single-promoter (GPEETp) expression vector. In the prototypical pLEW100 dual-promoter vector, a T7 promoter drives the selectable marker and TetR-regulated GPEET promoter drives the gene of interest (incidentally, there do not appear to be any significant differe ...
REVIEW ARTICLE Regulation of Expression of the Integrated
... evidence suggests that the activity of a provirus is strongly dependent upon its chromosomal environment. A hospitable chromosomal environment may be a necessary, although perhaps not a sufficient pre-condition for expression. Moreover, the permissiveness of this chromosomal environment may be modul ...
... evidence suggests that the activity of a provirus is strongly dependent upon its chromosomal environment. A hospitable chromosomal environment may be a necessary, although perhaps not a sufficient pre-condition for expression. Moreover, the permissiveness of this chromosomal environment may be modul ...
Th17/Treg ratio derived using DNA methylation asthmatic response
... shown to be higher in subjects with allergic asthma compared to healthy controls [3,4]. The percentage of Th17 cells and IL-17 levels in peripheral blood have been shown to be significantly elevated 24 hours after allergen challenge in dual responders compared to early responders or healthy controls ...
... shown to be higher in subjects with allergic asthma compared to healthy controls [3,4]. The percentage of Th17 cells and IL-17 levels in peripheral blood have been shown to be significantly elevated 24 hours after allergen challenge in dual responders compared to early responders or healthy controls ...
Probability – Parts 1, 3, Conclusion ?`s
... sickle cell trait, individuals may want to know whether or not future children will have the trait. If the pattern of how the trait is inherited and the individual’s family pedigree are known, doctors and genetic counselors can calculate the probability that an individual will express a trait. In Ac ...
... sickle cell trait, individuals may want to know whether or not future children will have the trait. If the pattern of how the trait is inherited and the individual’s family pedigree are known, doctors and genetic counselors can calculate the probability that an individual will express a trait. In Ac ...
RNA-dependent RNA polymerase is an essential component of a
... • Their Rdp1 mutant construct is expressed at the same level, but with the mutation normally silent genes are expressed • There is a similar level of Swi6 and H3K9me in the whole cell, but less at the otr1R region and centriole in the mutant; problem with heterochromatin assembly • Heterochromatin a ...
... • Their Rdp1 mutant construct is expressed at the same level, but with the mutation normally silent genes are expressed • There is a similar level of Swi6 and H3K9me in the whole cell, but less at the otr1R region and centriole in the mutant; problem with heterochromatin assembly • Heterochromatin a ...
Altered adherence properties of a Streptococcus
... the late exponential phase of growth in batch culture. The expression of CAT enzyme activity from the p-cshA+at promoter fusion was 28% decreased in early stationary phase cell extracts of mutant strain OB528 in which the hppA (oligopeptide-binding lipoprotein) gene was insertionally inactivated. Th ...
... the late exponential phase of growth in batch culture. The expression of CAT enzyme activity from the p-cshA+at promoter fusion was 28% decreased in early stationary phase cell extracts of mutant strain OB528 in which the hppA (oligopeptide-binding lipoprotein) gene was insertionally inactivated. Th ...
Gene Regulatory Network of Ikaros in T cell development and
... Ikaros is a master regulator of lymphogenesis, especially critical for lymphoid differentiation and maturation. Recurrent genomic lesions of Ikaros have been found associated with high risks of relapse of leukemia and poor outcome of therapy. However, it remains unclear about the gene regulatory net ...
... Ikaros is a master regulator of lymphogenesis, especially critical for lymphoid differentiation and maturation. Recurrent genomic lesions of Ikaros have been found associated with high risks of relapse of leukemia and poor outcome of therapy. However, it remains unclear about the gene regulatory net ...
Regionalization in the mammalian telencephalon - Fishell Lab
... layers of cortex are born sequentially, at distinct times, over a much more protracted period of development. The possibility that regional determination occurs at different times in different mammals warrants further investigation. Another issue that arises from these experiments is whether all cel ...
... layers of cortex are born sequentially, at distinct times, over a much more protracted period of development. The possibility that regional determination occurs at different times in different mammals warrants further investigation. Another issue that arises from these experiments is whether all cel ...
Polarity in Cell Division: Minireview What Frames Thy Fearful
... In a recent Cell paper, Yu et al. (2000) reported another important new component required for the asymmetric localization of Inscuteable. They used the central domain of Inscuteable, which is necessary and sufficient for its asymmetric localization as well as its ability to control spindle orientat ...
... In a recent Cell paper, Yu et al. (2000) reported another important new component required for the asymmetric localization of Inscuteable. They used the central domain of Inscuteable, which is necessary and sufficient for its asymmetric localization as well as its ability to control spindle orientat ...
Root organization and gene expression patterns
... These initials, or histogens (Hanstein, 1868) contribute to the initiation of different tissues; for example, in the most common closed type in monocotyledonous plants (e.g. Poaceae) there are three initial layers, the plerome (vascular cylinder), the periblem/dermatogen (cortex and epidermis) and t ...
... These initials, or histogens (Hanstein, 1868) contribute to the initiation of different tissues; for example, in the most common closed type in monocotyledonous plants (e.g. Poaceae) there are three initial layers, the plerome (vascular cylinder), the periblem/dermatogen (cortex and epidermis) and t ...
Gene Codon Composition Determines Differentiation
... milk–PBS and probed with fluorescein isothiocyanate-conjugated monoclonal antibody against keratin 14 (K14; Covance). Fixed KCs were probed with antibody against involucrin protein (Covance), followed by fluorescein isothiocyanate-conjugated secondary antibody. Nuclei were counterstained by 4⬘,6⬘-di ...
... milk–PBS and probed with fluorescein isothiocyanate-conjugated monoclonal antibody against keratin 14 (K14; Covance). Fixed KCs were probed with antibody against involucrin protein (Covance), followed by fluorescein isothiocyanate-conjugated secondary antibody. Nuclei were counterstained by 4⬘,6⬘-di ...
Investigation of the role of the Inflammasome triggering HIN200
... AIM2, a unique cytosolic DNA sensor which instigates the formation of the inflammasome yielding cell death via IL-1β and IL-182. This project sought to develop a novel subcongenic mouse model containing the HIN 200 locus, B10.Yaa.Bxs3.Ifi to investigate the potential role of this gene family in SLE ...
... AIM2, a unique cytosolic DNA sensor which instigates the formation of the inflammasome yielding cell death via IL-1β and IL-182. This project sought to develop a novel subcongenic mouse model containing the HIN 200 locus, B10.Yaa.Bxs3.Ifi to investigate the potential role of this gene family in SLE ...
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes
... chondrocytes. Activating six mutations in FGFR3 tyrosine kinase cause several forms of human skeletal dysplasia, there are four ways to identify different patients by molecular analysis: Hypochondrodysplasia, achondrodysplasia, thanatophoric dysplasia type I (TD1) and II (TD2). Previously, several s ...
... chondrocytes. Activating six mutations in FGFR3 tyrosine kinase cause several forms of human skeletal dysplasia, there are four ways to identify different patients by molecular analysis: Hypochondrodysplasia, achondrodysplasia, thanatophoric dysplasia type I (TD1) and II (TD2). Previously, several s ...
Meristematic sculpting in fruit development
... cells of the corpus can divide in all planes. Superimposed on this layer structure, the SAM can be divided into three functional zones. The central zone is maintained by a low cell division rate that generates cells for the peripheral zone and the rib meristem. The peripheral zone is responsible for ...
... cells of the corpus can divide in all planes. Superimposed on this layer structure, the SAM can be divided into three functional zones. The central zone is maintained by a low cell division rate that generates cells for the peripheral zone and the rib meristem. The peripheral zone is responsible for ...