The reverse control of irreversible biological processes
... In this box, we explain how the attractor landscape and phenotype landscape are obtained with the Boolean network model. In the Boolean network model, each node has two discrete states: turned ON (denoted as 1) or turned OFF (denoted as 0). We consider a toy example with three nodes: a, b, and c. Th ...
... In this box, we explain how the attractor landscape and phenotype landscape are obtained with the Boolean network model. In the Boolean network model, each node has two discrete states: turned ON (denoted as 1) or turned OFF (denoted as 0). We consider a toy example with three nodes: a, b, and c. Th ...
is involved in hair formation and spermatogenesis in mice gene
... mouse Ovo share 73% identity with equivalent segments of Drosophila Ovo/Svb (Garfinkel et al. 1994) and 94% identity with human Ovo1 (hOvo1; Chidambaram et al. 1997). On the basis of this similarity, we will refer to our sequence as mouse Ovo1a (mOvo1a). As this work was in progress, the sequence of ...
... mouse Ovo share 73% identity with equivalent segments of Drosophila Ovo/Svb (Garfinkel et al. 1994) and 94% identity with human Ovo1 (hOvo1; Chidambaram et al. 1997). On the basis of this similarity, we will refer to our sequence as mouse Ovo1a (mOvo1a). As this work was in progress, the sequence of ...
Transcriptional control of glial cell development in Drosophila
... and are easily identified by position, and by a large array of markers. Nearly all embryonic glial lineages have been completely described from progenitor to fully differentiated glia (Bossing et al., 1996; Ito et al., 1995; Schmid et al., 1999; Schmidt et al., 1997). Drosophila has also long been a ...
... and are easily identified by position, and by a large array of markers. Nearly all embryonic glial lineages have been completely described from progenitor to fully differentiated glia (Bossing et al., 1996; Ito et al., 1995; Schmid et al., 1999; Schmidt et al., 1997). Drosophila has also long been a ...
Modulation of CTCF Insulator Function by
... treatment with the inhibitor of transcriptional elongation, 5,6-dichloro-1-b-D-ribofuranosyl-benzimidazole, permitted transcription of many immediate-early genes but abrogated LPS-induced LINoCR expression, IKKa recruitment, histone H3 phosphoacetylation, and specific CTCF/ cohesin eviction. These d ...
... treatment with the inhibitor of transcriptional elongation, 5,6-dichloro-1-b-D-ribofuranosyl-benzimidazole, permitted transcription of many immediate-early genes but abrogated LPS-induced LINoCR expression, IKKa recruitment, histone H3 phosphoacetylation, and specific CTCF/ cohesin eviction. These d ...
Targeting construct, targeting, and generation of Gclc floxed
... were microinjected into C57BL/6J blastocysts and transferred into pseudo-pregnant mothers. The resulting chimeric male mice were bred to female C57BL/6J mice, and germ line transmission was identified by both Southern blot and PCR analysis. For abbreviations, the three different Gclc alleles (sup Fi ...
... were microinjected into C57BL/6J blastocysts and transferred into pseudo-pregnant mothers. The resulting chimeric male mice were bred to female C57BL/6J mice, and germ line transmission was identified by both Southern blot and PCR analysis. For abbreviations, the three different Gclc alleles (sup Fi ...
Cloning and Expression of Endoglucanase genes from Trichoderma
... 3-β-glucanases and β-1, 6-glucanases and about 15 genes are known to encode polypeptides with glucanase or related enzymatic activities [3 ]. Some of these glucanases have roles during cell separation, while others exhibit transglycosylase activity and may be involved in extending and rearranging 1, ...
... 3-β-glucanases and β-1, 6-glucanases and about 15 genes are known to encode polypeptides with glucanase or related enzymatic activities [3 ]. Some of these glucanases have roles during cell separation, while others exhibit transglycosylase activity and may be involved in extending and rearranging 1, ...
Simple allelic-phenotype diversity and differentiation
... derived from the duplication of a single genome and – at least initially – there is no significant differentiation between duplicate genomes. Conversely, allopolyploids are derived from interspecific hybridisation, and therefore comprise two (or more) differentiated genomes. However, as species boun ...
... derived from the duplication of a single genome and – at least initially – there is no significant differentiation between duplicate genomes. Conversely, allopolyploids are derived from interspecific hybridisation, and therefore comprise two (or more) differentiated genomes. However, as species boun ...
Gill: Gene Regulation II
... Histone Code Hypothesis Histone modifications serve to recruit other proteins by specific recognition of the modified histone via protein domains specialized for such purposes, rather than through simply stabilizing or destabilizing the interaction between histone and the underlying DNA. histone mo ...
... Histone Code Hypothesis Histone modifications serve to recruit other proteins by specific recognition of the modified histone via protein domains specialized for such purposes, rather than through simply stabilizing or destabilizing the interaction between histone and the underlying DNA. histone mo ...
Haploid embryonic stem cells serve as a new tool for mammalian
... stem (ES) cells have recently been established successfully in mice and monkeys, from either parthenogenetic or androgenetic haploid embryos. These haploid ES cells maintain haploidy and stable growth during extensive in vitro culture, express pluripotent markers, and possess the ability to differen ...
... stem (ES) cells have recently been established successfully in mice and monkeys, from either parthenogenetic or androgenetic haploid embryos. These haploid ES cells maintain haploidy and stable growth during extensive in vitro culture, express pluripotent markers, and possess the ability to differen ...
gene transfer - Bio-Rad
... of B. graminis f. sp. hordei isolate K1 approximately 24 hr after bombardment. Microscopic fungal growth was visible 3–4 days after inoculation as the formation of aerial hyphae and conidiophores. In the vast majority of sections, formation of fungal colonies originated from single infected cells ex ...
... of B. graminis f. sp. hordei isolate K1 approximately 24 hr after bombardment. Microscopic fungal growth was visible 3–4 days after inoculation as the formation of aerial hyphae and conidiophores. In the vast majority of sections, formation of fungal colonies originated from single infected cells ex ...
Recombinant Paper Plasmids Cut-and
... yielding “sticky ends,” single strands of nucleotide bases capable of binding with complementary sticky ends. By using enzymes that will cut the DNA on either side of the gene, the gene can be clipped out of the DNA strand. Once scientists obtain the gene they are looking for, they must somehow get ...
... yielding “sticky ends,” single strands of nucleotide bases capable of binding with complementary sticky ends. By using enzymes that will cut the DNA on either side of the gene, the gene can be clipped out of the DNA strand. Once scientists obtain the gene they are looking for, they must somehow get ...
Male idiopathic infertility and the TP53 polymorphism in
... spermatogenesis is crucial to fertility. Spontaneous germ cell death has been recognized as a normal cellular process in the mammalian testis (Kerr, 1992). Cell suppression has been found at different stages of development including in spermatogonia (Huckins, 1978; Allan et al., 1992), spermatocytes ...
... spermatogenesis is crucial to fertility. Spontaneous germ cell death has been recognized as a normal cellular process in the mammalian testis (Kerr, 1992). Cell suppression has been found at different stages of development including in spermatogonia (Huckins, 1978; Allan et al., 1992), spermatocytes ...
Plant germline formation: common concepts and developmental
... distinguished from the surrounding cells by its subepidermal localization and its enlarged size. In the sexual model species Arabidopsis, as in most species, the archesporial cell directly differentiates into a megaspore mother cell (MMC) without intervening divisions. The MMC is defined by its comm ...
... distinguished from the surrounding cells by its subepidermal localization and its enlarged size. In the sexual model species Arabidopsis, as in most species, the archesporial cell directly differentiates into a megaspore mother cell (MMC) without intervening divisions. The MMC is defined by its comm ...
Transmission disequilibrium test and haplotype analysis of the MCP-1
... inflammatory disorder [9-12]. An indirect evidence was provided by imaging studies which demonstrated both increases and decreases in volumes of nuclei and white matter structures of TS cases [30], because these imaging results have been reported to be closely associated to streptococcal infection [ ...
... inflammatory disorder [9-12]. An indirect evidence was provided by imaging studies which demonstrated both increases and decreases in volumes of nuclei and white matter structures of TS cases [30], because these imaging results have been reported to be closely associated to streptococcal infection [ ...
File
... b) The RNA fragments enhance protein synthesis by the mRNA. c) The RNA fragments bind the ribosome to enhance use of the mRNA and protein synthesis. d) The target mRNA is blocked from being used in translation. e) The RNA fragments act on the ribosome to shut down translation of all mRNAs. © 2014 Pe ...
... b) The RNA fragments enhance protein synthesis by the mRNA. c) The RNA fragments bind the ribosome to enhance use of the mRNA and protein synthesis. d) The target mRNA is blocked from being used in translation. e) The RNA fragments act on the ribosome to shut down translation of all mRNAs. © 2014 Pe ...
Imprinted SNRPN within chromosome territories
... territories. They analyzed the spatial relationships between chromosome territories and splicing machinery or the localization of DNA replication sites in the territories. Splicing machinery components are concentrated in between chromosome territories, and DNA replication foci are located in the in ...
... territories. They analyzed the spatial relationships between chromosome territories and splicing machinery or the localization of DNA replication sites in the territories. Splicing machinery components are concentrated in between chromosome territories, and DNA replication foci are located in the in ...
Chromatin: A sticky silence
... that a critical concentration of silencing factors must be reached to establish the repressed state. This can be provided by proximity to centromeric heterochromatin or telomeres, which provide multiple weak binding sites or a ‘molecular sink’ for the limiting species. This is most strongly supporte ...
... that a critical concentration of silencing factors must be reached to establish the repressed state. This can be provided by proximity to centromeric heterochromatin or telomeres, which provide multiple weak binding sites or a ‘molecular sink’ for the limiting species. This is most strongly supporte ...
Winter 2010
... sickle cell trait carriers (AS) in several studies; however, there are a few studies that have not found an increased rate of pregnancy related complications. A 1983 study by Tuck et. al.10 looked at 334 pregnancies of women with sickle cell trait compared to 717 patients of the same racial and soci ...
... sickle cell trait carriers (AS) in several studies; however, there are a few studies that have not found an increased rate of pregnancy related complications. A 1983 study by Tuck et. al.10 looked at 334 pregnancies of women with sickle cell trait compared to 717 patients of the same racial and soci ...
Sickle Cell Disease SS – No Sickle Cell
... • Sickle cell is a genetic condition that causes the red protein in blood (hemoglobin) to make the blood cells rigid and pointy. • The gene for sickle trait is spread throughout the world. • It was most common in the areas where there was a lot of malaria because sickle trait actually helps people s ...
... • Sickle cell is a genetic condition that causes the red protein in blood (hemoglobin) to make the blood cells rigid and pointy. • The gene for sickle trait is spread throughout the world. • It was most common in the areas where there was a lot of malaria because sickle trait actually helps people s ...
HIGH FREQUENCY GENE TARGETING USING INSERTIONAL
... vectors derived from the same genomic clone as ourselves, but with more homology to the Cftr gene than is present in our vectors. All other intrinsic factors being equal, we conclude that our Cftr insertional vectors give up to ~200-fold improved gene targeting frequencies over those reported for C ...
... vectors derived from the same genomic clone as ourselves, but with more homology to the Cftr gene than is present in our vectors. All other intrinsic factors being equal, we conclude that our Cftr insertional vectors give up to ~200-fold improved gene targeting frequencies over those reported for C ...
Mendel`sWork
... • When F1 hybrids were allowed to selfpollinate a 3:1 ratio of the 2 varieties occurred in the F2 generation. ...
... • When F1 hybrids were allowed to selfpollinate a 3:1 ratio of the 2 varieties occurred in the F2 generation. ...
The principles and methods formulated by Gregor Mendel provide
... People who are heterozygous for the sickle cell allele almost never experience the symptoms of sickle cell anemia that are observed in people who are homozygous for the sickle cell allele. These symptoms include pain and organ damage due to blocked circulation and anemia (low red blood cell levels) ...
... People who are heterozygous for the sickle cell allele almost never experience the symptoms of sickle cell anemia that are observed in people who are homozygous for the sickle cell allele. These symptoms include pain and organ damage due to blocked circulation and anemia (low red blood cell levels) ...
The Drosophila Expression System.
... • Your choice of DES® vector for inducible (pMT/V5-His), inducible/secreted (pMT/BiP/V5-His), or constitutive expression (pAc5.1/V5-His) • A positive expression control • pCoBlast or pCoHygro for stable selection ...
... • Your choice of DES® vector for inducible (pMT/V5-His), inducible/secreted (pMT/BiP/V5-His), or constitutive expression (pAc5.1/V5-His) • A positive expression control • pCoBlast or pCoHygro for stable selection ...
Identification of Genes Mediating Drosophila Follicle Cell Progenitor
... modifiers of variegation spanning nearly 70% of Drosophila euchromatin to identify new genes influencing follicle progenitor epigenetic maturation. The eight genes found include chromatin modifiers, but also cell cycle regulators and transcription factors. Five of the modifier genes accelerate the acqui ...
... modifiers of variegation spanning nearly 70% of Drosophila euchromatin to identify new genes influencing follicle progenitor epigenetic maturation. The eight genes found include chromatin modifiers, but also cell cycle regulators and transcription factors. Five of the modifier genes accelerate the acqui ...
Linker histone H1 in early mouse embryogenesis
... studies (Clarke et al., 1992; Stein and Schultz, 2000). The antibody raised against phosphorylated H1 (H1P) in Tetrahymena, which has been demonstrated to recognize only one of the mouse H1P subtypes (histone H1b; Chadee et al., 1995), reacted with one immunoreactive protein, present only in the mou ...
... studies (Clarke et al., 1992; Stein and Schultz, 2000). The antibody raised against phosphorylated H1 (H1P) in Tetrahymena, which has been demonstrated to recognize only one of the mouse H1P subtypes (histone H1b; Chadee et al., 1995), reacted with one immunoreactive protein, present only in the mou ...