stem cell
... transplanted nuclei came from cells of an early embryo, which are relatively undifferentiated cells. But with nuclei from the fully differentiated intestinal cells of a tadpole, fewer than 2% of the eggs developed into normal tadpoles, and most of the embryos died at a much earlier developmental sta ...
... transplanted nuclei came from cells of an early embryo, which are relatively undifferentiated cells. But with nuclei from the fully differentiated intestinal cells of a tadpole, fewer than 2% of the eggs developed into normal tadpoles, and most of the embryos died at a much earlier developmental sta ...
Supplementary Data File Supplementary Figures Figure S1
... Table S10. Top ten statistically significant KEGG pathways (adjusted P-value < 0.01) in the two-group cancer versus normal comparisons. We report the top ten pathways or all the significant pathways if there were less than ten for A. AML vs 1000 Genomes, B. GBM vs 1000 Genomes, C. OVC vs 1000 Genom ...
... Table S10. Top ten statistically significant KEGG pathways (adjusted P-value < 0.01) in the two-group cancer versus normal comparisons. We report the top ten pathways or all the significant pathways if there were less than ten for A. AML vs 1000 Genomes, B. GBM vs 1000 Genomes, C. OVC vs 1000 Genom ...
View - Max-Planck
... The expression of NKX2.1 was studied by wholemount in situ hybridization in young chick embryos (HH3-21; Hamburger and Hamilton 1951) probing with the 1784-bp BamHI cDNA fragment. In situ hybridization and histology of whole embryos was performed as described, except that specimens from all stages w ...
... The expression of NKX2.1 was studied by wholemount in situ hybridization in young chick embryos (HH3-21; Hamburger and Hamilton 1951) probing with the 1784-bp BamHI cDNA fragment. In situ hybridization and histology of whole embryos was performed as described, except that specimens from all stages w ...
New techniques in plant biotechnology
... EU legislation, the government says it can only make this judgement when an actual application is submitted. Thus a situation is created in which both parties are waiting for each other. Advice This advisory report, which to some degree has a informative character, discusses six new techniques: ‘rev ...
... EU legislation, the government says it can only make this judgement when an actual application is submitted. Thus a situation is created in which both parties are waiting for each other. Advice This advisory report, which to some degree has a informative character, discusses six new techniques: ‘rev ...
Pluripotent cells (stem cells) - an der Universität Duisburg
... of neuritic outgrowth. When these cells were replated as a monolayer, many cells had a neuronal appearance and expressed neuronal markers. The cells generated action potentials and expressed tetrodotoxin-sensitive sodium channels (Bain et al. 1995). Cells expressing glial precursor markers were obta ...
... of neuritic outgrowth. When these cells were replated as a monolayer, many cells had a neuronal appearance and expressed neuronal markers. The cells generated action potentials and expressed tetrodotoxin-sensitive sodium channels (Bain et al. 1995). Cells expressing glial precursor markers were obta ...
Clinical-Laboratory-Hematology-2nd-Edition
... predisposes individuals to retinoblastomas and other tumors when only one functional copy is present. Rb is present all throughout the cell cycle. Phosphorylations vary with each cell-cycle phase. In its hypophosphorylated (active) state, Rb has antiproliferative effects, inhibiting cell cycling. It ...
... predisposes individuals to retinoblastomas and other tumors when only one functional copy is present. Rb is present all throughout the cell cycle. Phosphorylations vary with each cell-cycle phase. In its hypophosphorylated (active) state, Rb has antiproliferative effects, inhibiting cell cycling. It ...
WOX4 and WOX14 act downstream of the PXY
... a role for localised CLE41 expression providing a positional signal to PXY that is required for correct orientation of the division plane in vascular stem cells (supplementary material Fig. S1A,B) (Etchells and Turner, 2010). Although these experiments are all consistent with a role for PXY and CLE4 ...
... a role for localised CLE41 expression providing a positional signal to PXY that is required for correct orientation of the division plane in vascular stem cells (supplementary material Fig. S1A,B) (Etchells and Turner, 2010). Although these experiments are all consistent with a role for PXY and CLE4 ...
WOX4 and WOX14 act downstream of the PXY
... Increases in WOX14 expression were not dependent on functional WOX4, as a clear WOX14 response to TDIF was observed in wox4 mutant lines (Fig. 3), demonstrating that WOX14 is not a downstream target of WOX4. Inflorescence stems represent a developmental series with most recently derived vascular tis ...
... Increases in WOX14 expression were not dependent on functional WOX4, as a clear WOX14 response to TDIF was observed in wox4 mutant lines (Fig. 3), demonstrating that WOX14 is not a downstream target of WOX4. Inflorescence stems represent a developmental series with most recently derived vascular tis ...
Functional Divergence of the Nuclear Receptor NR2C1
... evolutionary analysis of NR sequence evolution, which identified NR2C1 as a candidate for AGR-based experimental assays. Our functional assays revealed NR2C1 as a potential modulator of pluripotentiality during hominid evolution. Our investigation was divided into three phases. In the first phase, we ...
... evolutionary analysis of NR sequence evolution, which identified NR2C1 as a candidate for AGR-based experimental assays. Our functional assays revealed NR2C1 as a potential modulator of pluripotentiality during hominid evolution. Our investigation was divided into three phases. In the first phase, we ...
Developmental Biology and Morphogenesis of the Face, Lip and
... Once mapped out these cells continue with their peak period of cell differentiation, proliferation, and migration through the second intrauterine month.While the classical picture of craniofacial morphogenesis can be framed upon the morphogenesis of primary germ layer cells (i.e., ectoderm, mesoderm ...
... Once mapped out these cells continue with their peak period of cell differentiation, proliferation, and migration through the second intrauterine month.While the classical picture of craniofacial morphogenesis can be framed upon the morphogenesis of primary germ layer cells (i.e., ectoderm, mesoderm ...
A dioxin sensitive gene, mammalian WAPL, is implicated in
... interfering RNA (siRNA) induces cell death [3]. These observations suggest that unscheduled changes in hWAPL expression can cause severe damage to cells. Thus, although more experiments are needed to provide direct evidence linking mammalianWAPL with TCDD-induced reproductive toxicity, the present s ...
... interfering RNA (siRNA) induces cell death [3]. These observations suggest that unscheduled changes in hWAPL expression can cause severe damage to cells. Thus, although more experiments are needed to provide direct evidence linking mammalianWAPL with TCDD-induced reproductive toxicity, the present s ...
PDF
... were absent in all explants cultured with hydrocortisone only (Fig. 6). These blastemata exhibited a scarcity of cells and further growth of the regenerating spinal cord or fin was not observed. The epidermis became thickened and squamous and was accompanied by heavy molting. The results obtained wi ...
... were absent in all explants cultured with hydrocortisone only (Fig. 6). These blastemata exhibited a scarcity of cells and further growth of the regenerating spinal cord or fin was not observed. The epidermis became thickened and squamous and was accompanied by heavy molting. The results obtained wi ...
bluebird bio, Inc. - corporate
... Progress to late-stage clinical development of lentivirus based gene therapies and CAR T therapies will require enhanced characterization of the purified lentivirus product. LVV preparations are complex and utilize host cells that produce not only the viral particles of interest, but also a vari ...
... Progress to late-stage clinical development of lentivirus based gene therapies and CAR T therapies will require enhanced characterization of the purified lentivirus product. LVV preparations are complex and utilize host cells that produce not only the viral particles of interest, but also a vari ...
A Unified Statistical Framework for RNA Sequence Data from
... regression-type problem that aims at estimating W . Several algorithms have been proposed under this setting, including Cibersort (Newman et al., 2015) and csSAM (Shen-Orr et al., 2010). However, without knowing the signature matrix, deconvolution is highly nontrivial, and this line of methods inclu ...
... regression-type problem that aims at estimating W . Several algorithms have been proposed under this setting, including Cibersort (Newman et al., 2015) and csSAM (Shen-Orr et al., 2010). However, without knowing the signature matrix, deconvolution is highly nontrivial, and this line of methods inclu ...
Honors Biology Lab Manual
... make and control every cell within a living organism. DNA, which stands for deoxyribonucleic acid, resembles a long, spiraling ladder. It consists of just a few kinds of atoms: carbon, hydrogen, oxygen, nitrogen, and phosphorus. Combinations of these atoms form the sugar-phosphate backbone of the ...
... make and control every cell within a living organism. DNA, which stands for deoxyribonucleic acid, resembles a long, spiraling ladder. It consists of just a few kinds of atoms: carbon, hydrogen, oxygen, nitrogen, and phosphorus. Combinations of these atoms form the sugar-phosphate backbone of the ...
Three Full Blocks And Partial Time In Two Additional Blocks
... phenotype (i.e., not harmful). 2. Students fail to connect that phenotypes are controlled by proteins (rather than DNA). a. We will correlate a disease phenotype (sickle cell anemia) with a defective protein that’s encoded by a mutant gene. The defective protein aggregates and forms long fibers whic ...
... phenotype (i.e., not harmful). 2. Students fail to connect that phenotypes are controlled by proteins (rather than DNA). a. We will correlate a disease phenotype (sickle cell anemia) with a defective protein that’s encoded by a mutant gene. The defective protein aggregates and forms long fibers whic ...
Chapter 1: The Microbial World and You
... susceptible to mechanical breakage than that of Gram-positive bacteria. Consist of one or a few peptidoglycan layers and an outer membrane. Peptidoglycan is bonded to lipoproteins in: Outer membrane Periplasmic space: Region between outer membrane and plasma membrane. ...
... susceptible to mechanical breakage than that of Gram-positive bacteria. Consist of one or a few peptidoglycan layers and an outer membrane. Peptidoglycan is bonded to lipoproteins in: Outer membrane Periplasmic space: Region between outer membrane and plasma membrane. ...
Chapter 4: Functional Anatomy of Procaryotic and Eucaryotic Cells
... u Longer than fimbriae. u Cells only have one or two sex pili. u Attach two cells together, and allow the transfer of genetic material (DNA) between cells. u Medically important because allow for the transfer of antibiotic resistance genes from one cell to another. ...
... u Longer than fimbriae. u Cells only have one or two sex pili. u Attach two cells together, and allow the transfer of genetic material (DNA) between cells. u Medically important because allow for the transfer of antibiotic resistance genes from one cell to another. ...
Presentation Title - NCTM Illuminations
... • Sickle cell is a genetic condition that causes the red protein in blood (hemoglobin) to make the blood cells rigid and pointy. • The gene for sickle trait is spread throughout the world. • It was most common in the areas where there was a lot of malaria because sickle trait actually helps people s ...
... • Sickle cell is a genetic condition that causes the red protein in blood (hemoglobin) to make the blood cells rigid and pointy. • The gene for sickle trait is spread throughout the world. • It was most common in the areas where there was a lot of malaria because sickle trait actually helps people s ...
WormBase-Oct2004 - Gene Ontology Consortium
... Textpresso's two major elements are a collection of the full text of scientific articles split into individual sentences, and the implementation of categories of terms for which a database of articles and individual sentences can be searched. The categories are classes of biological concepts (e.g., ...
... Textpresso's two major elements are a collection of the full text of scientific articles split into individual sentences, and the implementation of categories of terms for which a database of articles and individual sentences can be searched. The categories are classes of biological concepts (e.g., ...
Transvection, nuclear structure, and chromatin proteins.
... including plants and vertebrates, also exists (reviewed by Grell, 1969). For example, Arnoldus et al. (1991) have found evidence for tissue specific somatic pairing in humans, suggesting that pairing is not only developmentally regulated but a form of regulation in itself. ...
... including plants and vertebrates, also exists (reviewed by Grell, 1969). For example, Arnoldus et al. (1991) have found evidence for tissue specific somatic pairing in humans, suggesting that pairing is not only developmentally regulated but a form of regulation in itself. ...
Full Text - American Diabetes Association
... measured the levels of the mRNAs encoding tryptophan hydroxylases TPH1 and TPH2, the two isoforms of the TPH enzyme that catalyze the initial and committed step in serotonin synthesis. The brain uses both isoforms, while nonneuronal tissues such as the gut express predominantly TPH1 (33). We could d ...
... measured the levels of the mRNAs encoding tryptophan hydroxylases TPH1 and TPH2, the two isoforms of the TPH enzyme that catalyze the initial and committed step in serotonin synthesis. The brain uses both isoforms, while nonneuronal tissues such as the gut express predominantly TPH1 (33). We could d ...
How to make knockout animals?
... Applications of Transgenic Animals Transgenic mice are often generated to 1. characterize the ability of a promoter to direct tissue-specific gene expression e.g. a promoter can be attached to a reporter gene such as LacZ or GFP 2. examine the effects of overexpressing and misexpressing endogenous ...
... Applications of Transgenic Animals Transgenic mice are often generated to 1. characterize the ability of a promoter to direct tissue-specific gene expression e.g. a promoter can be attached to a reporter gene such as LacZ or GFP 2. examine the effects of overexpressing and misexpressing endogenous ...
Chromosome Instability Mutants of Saccharomyces cerevisiae That Are Defective in Microtubule-Mediated Processes.
... that consists of an array of microtubules (the mitotic spindle). Yeast cells with impaired tubulin activity show unfaithful mitotic chromosome transmission (18, 55). These cells lose chromosomes at higher frequencies than do wild-type cells; that is, cells that have failed to inherit a particular ch ...
... that consists of an array of microtubules (the mitotic spindle). Yeast cells with impaired tubulin activity show unfaithful mitotic chromosome transmission (18, 55). These cells lose chromosomes at higher frequencies than do wild-type cells; that is, cells that have failed to inherit a particular ch ...
Smchd1 regulates a subset of autosomal genes subject to
... imprinted gene cluster is also disrupted, with Slc22a3 showing biallelic expression in the absence of Smchd1. In both cases, the disruption was not due to loss of the differential methylation that marks the imprint control region, but affected genes remote from this primary imprint controlling eleme ...
... imprinted gene cluster is also disrupted, with Slc22a3 showing biallelic expression in the absence of Smchd1. In both cases, the disruption was not due to loss of the differential methylation that marks the imprint control region, but affected genes remote from this primary imprint controlling eleme ...