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... become Pfr and translocate into the nucleus, where phys regulate the transcription of a number of genes that mediate plant light responses [12,13]. Interestingly, phy proteins form granular structures called photobodies (originally called nuclear speckles) in the nucleus in response to light. Althou ...
... become Pfr and translocate into the nucleus, where phys regulate the transcription of a number of genes that mediate plant light responses [12,13]. Interestingly, phy proteins form granular structures called photobodies (originally called nuclear speckles) in the nucleus in response to light. Althou ...
Protein O-linked β-N-acetylglucosamine
... we will discuss in more detail the fact that insulin increases both tyrosine phosphorylation and O-GlcNAcylation of OGT, leading to increased activity and transient translocation from nucleus to cytoplasm [74,75]. The Nterminal domain of OGT contains multiple tetratricopeptide repeats (TPR), which m ...
... we will discuss in more detail the fact that insulin increases both tyrosine phosphorylation and O-GlcNAcylation of OGT, leading to increased activity and transient translocation from nucleus to cytoplasm [74,75]. The Nterminal domain of OGT contains multiple tetratricopeptide repeats (TPR), which m ...
Properties of a newly characterized protein of the bovine - K-REx
... and the FAD was found to be associated with the large a-subunit The function of the a-subunit is as of yet unknown. ...
... and the FAD was found to be associated with the large a-subunit The function of the a-subunit is as of yet unknown. ...
Metabolic flux profiling of recombinant protein secreting Pichia
... Several studies have reported on the impact of recombinant protein over expression on different growth parameters of yeast, such as maximum growth rate, biomass yield or substrate specific consumption rate [11–14], suggesting a potential impact on the cell’s central metabolism. Nevertheless, the ...
... Several studies have reported on the impact of recombinant protein over expression on different growth parameters of yeast, such as maximum growth rate, biomass yield or substrate specific consumption rate [11–14], suggesting a potential impact on the cell’s central metabolism. Nevertheless, the ...
Eater, a Transmembrane Protein Mediating
... (C) Schematic depiction of the Eater protein as a type I membrane protein with an extracellular region consisting of an N-terminal domain (black oval), EGF-like repeats (boxes), a transmembrane region, and a short intracellular tail. Predicted glycosylation (lollipops) and tyrosine phosphorylation ( ...
... (C) Schematic depiction of the Eater protein as a type I membrane protein with an extracellular region consisting of an N-terminal domain (black oval), EGF-like repeats (boxes), a transmembrane region, and a short intracellular tail. Predicted glycosylation (lollipops) and tyrosine phosphorylation ( ...
Sensitive Interaction between Raptor a
... ies (Figure 1B). Unlike raptor, GL remains bound to mTOR in buffers containing the detergent Triton X-100, suggesting that the GL-mTOR interaction does not require raptor. In addition to HEK-293T cells, we also detected the endogenous mTOR-GL complex in mouse NIH-3T3 and C2C12 cell lines (data no ...
... ies (Figure 1B). Unlike raptor, GL remains bound to mTOR in buffers containing the detergent Triton X-100, suggesting that the GL-mTOR interaction does not require raptor. In addition to HEK-293T cells, we also detected the endogenous mTOR-GL complex in mouse NIH-3T3 and C2C12 cell lines (data no ...
Effects of Long-Term Thyroid Hormone Level Alterations, n
... functions, oxidative stress markers and cell death, changes in serum lipid levels, activities of key enzymes of thyroid hormone metabolism, activity of acetylcholine esterase and membrane anisotropy, as well as mobile behavior and thermal sensitivity. Additionally we also mention our pilot experimen ...
... functions, oxidative stress markers and cell death, changes in serum lipid levels, activities of key enzymes of thyroid hormone metabolism, activity of acetylcholine esterase and membrane anisotropy, as well as mobile behavior and thermal sensitivity. Additionally we also mention our pilot experimen ...
1-3 flagellum - Instituto de Higiene
... The flagellum and flagellar pocket are distinctive organelles present among all of the trypanosomatid protozoa. Currently, recognized functions for these organelles include generation of motility for the flagellum and dedicated secretory and endocytic activities for the flagellar pocket. The flagell ...
... The flagellum and flagellar pocket are distinctive organelles present among all of the trypanosomatid protozoa. Currently, recognized functions for these organelles include generation of motility for the flagellum and dedicated secretory and endocytic activities for the flagellar pocket. The flagell ...
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... sensitive transient drop of the membrane potential. The time required for the potential to be rebuilt by respiration was, on other hand, largely increased by AEA in the concentration dependent fashion (see inset in Fig. 3A). The extent of membrane potential generated by glutamate + malate addition ( ...
... sensitive transient drop of the membrane potential. The time required for the potential to be rebuilt by respiration was, on other hand, largely increased by AEA in the concentration dependent fashion (see inset in Fig. 3A). The extent of membrane potential generated by glutamate + malate addition ( ...
Effects of rare codon clusters on high-level expression
... system, a pL promoter controls transcription o f the heterologous product in an E. coli K-12 host containing a chromosomal copy o f ~. ci857 gene. A temperature shiti upwards induced product expression. Growth and expression occurred in 10 liter fermenters. Western analysis indicated a full-length p ...
... system, a pL promoter controls transcription o f the heterologous product in an E. coli K-12 host containing a chromosomal copy o f ~. ci857 gene. A temperature shiti upwards induced product expression. Growth and expression occurred in 10 liter fermenters. Western analysis indicated a full-length p ...
Factors Influencing the Early Phases of Growth of
... (1.25x 10-8 cells/ml.; Lodge & Hinshelwood, 19483). This age refers to the parent culture and the initial population of a daughter culture inoculated from it was 1/250of the population of the parent, at that age, in our experiments. The present work was undertaken because we found that inocula deriv ...
... (1.25x 10-8 cells/ml.; Lodge & Hinshelwood, 19483). This age refers to the parent culture and the initial population of a daughter culture inoculated from it was 1/250of the population of the parent, at that age, in our experiments. The present work was undertaken because we found that inocula deriv ...
Life and death of transcriptional co
... proteasome system in response to toxic proteins.65 The formation of aggresome is a cellular protective mechanism to sequester Increasing evidence has provided functional implications of cytoplasmic protein aggregates or to deliver them for disposal p300 modification and metabolic stability in epigen ...
... proteasome system in response to toxic proteins.65 The formation of aggresome is a cellular protective mechanism to sequester Increasing evidence has provided functional implications of cytoplasmic protein aggregates or to deliver them for disposal p300 modification and metabolic stability in epigen ...
Life Inside a Microtubule
... a direct relationship between a given kinase and actin phosphorylation1. For example, Ser and Tyr residues on actin are phosphorylated in response to insulin via unknown kinases, leading to reduced DNAse I binding1 (Fig. 1). Likewise, activation of the p21-activated kinase PAK1 leads to actin phosph ...
... a direct relationship between a given kinase and actin phosphorylation1. For example, Ser and Tyr residues on actin are phosphorylated in response to insulin via unknown kinases, leading to reduced DNAse I binding1 (Fig. 1). Likewise, activation of the p21-activated kinase PAK1 leads to actin phosph ...
The autophagy conundrum in cancer: influence of
... and autophagic clearance of certain cargo, such as organelles, and ubiquitinated or aggregated proteins, are mediated by specific targeting proteins (Narendra et al., 2008; Kirkin et al., 2009; Filimonenko et al., 2010). Autophagy is activated by limitations in glucose, amino acids and oxygen. Early ...
... and autophagic clearance of certain cargo, such as organelles, and ubiquitinated or aggregated proteins, are mediated by specific targeting proteins (Narendra et al., 2008; Kirkin et al., 2009; Filimonenko et al., 2010). Autophagy is activated by limitations in glucose, amino acids and oxygen. Early ...
NSPKU
... • A protein substitute contains NO Phe... But it contains all of the other amino acids in protein that your child needs. • Most protein substitutes also contain vitamins, minerals and other important nutrients to ensure your child is getting what they need. The protein substitute is an extremely imp ...
... • A protein substitute contains NO Phe... But it contains all of the other amino acids in protein that your child needs. • Most protein substitutes also contain vitamins, minerals and other important nutrients to ensure your child is getting what they need. The protein substitute is an extremely imp ...
The Amino Acid Sequences of the Myelin
... L-MAG also contains five segments of internal homology that resemble immunoglobulin domains, and are strikingly homologous to similar domains of the neural cell adhesion molecule and other members of the immunoglobulin gene superfamily. In addition, the two MAG proteins differ in the extent of their ...
... L-MAG also contains five segments of internal homology that resemble immunoglobulin domains, and are strikingly homologous to similar domains of the neural cell adhesion molecule and other members of the immunoglobulin gene superfamily. In addition, the two MAG proteins differ in the extent of their ...
212_spring_2005_Platelets
... • Exposure of flowing blood and platelets to subendothelial components • Platelets bind to the subendothelial collagen bound to von Willebrand factor (vWF), which is secreted from endothelial cells directly into the subendothelial space or adsorbed from plasma following endothelial cell secretion • ...
... • Exposure of flowing blood and platelets to subendothelial components • Platelets bind to the subendothelial collagen bound to von Willebrand factor (vWF), which is secreted from endothelial cells directly into the subendothelial space or adsorbed from plasma following endothelial cell secretion • ...
Glycolysi
... Irreversible, committed step in glycolysis Activation under low [ATP] or high [ADP and AMP] Phosphoryl group donor ATP PPi : some bacteria and protist, all plants ...
... Irreversible, committed step in glycolysis Activation under low [ATP] or high [ADP and AMP] Phosphoryl group donor ATP PPi : some bacteria and protist, all plants ...
On the role of gut microbiota in intestinal physiology and
... benefits. However, mechanistic knowledge of these has been limited, but are now becoming increasingly clear. We used germ-free mice to study three aspects of host physiology; the effects of the microbiota on small intestinal postnatal vascularization (I), small intestinal permeability (II), as well ...
... benefits. However, mechanistic knowledge of these has been limited, but are now becoming increasingly clear. We used germ-free mice to study three aspects of host physiology; the effects of the microbiota on small intestinal postnatal vascularization (I), small intestinal permeability (II), as well ...
HIGHLY VISCOUS DOUGH FORMING PROPERTIES OF MARAMA PROTEIN
... deformation analysis is non-destructive, it can provide some information on the types of molecular bonding that may be responsible for the structural stability of proteins (Mezger, 2006). A low tan δ value is often associated with a high degree of crosslinking (Tsiami, Bot, Agterof, & Groot, 1997; M ...
... deformation analysis is non-destructive, it can provide some information on the types of molecular bonding that may be responsible for the structural stability of proteins (Mezger, 2006). A low tan δ value is often associated with a high degree of crosslinking (Tsiami, Bot, Agterof, & Groot, 1997; M ...
Reducing Rice Seed Storage Protein Accumulation Leads to
... Copyright © 2010 American Society of Plant Biologists. All rights reserved. ...
... Copyright © 2010 American Society of Plant Biologists. All rights reserved. ...
Gene encoding the group B streptococcal protein R4, its
... prototypic reference antisera for R4 in double-diffusion (results not shown). The trypsin-extracted R4 showed a precipitin result with anti-R4 antiserum for both controls. As the classic example of pepsin sensitivity for pepsin at pH2, no precipitin result was shown. At pH4, pH6 and pH8, however, pr ...
... prototypic reference antisera for R4 in double-diffusion (results not shown). The trypsin-extracted R4 showed a precipitin result with anti-R4 antiserum for both controls. As the classic example of pepsin sensitivity for pepsin at pH2, no precipitin result was shown. At pH4, pH6 and pH8, however, pr ...
Sixth Southeast Enzyme Conference
... The Chemistry Department at Georgia State University is the lead organizer and founder of the Southeast Enzyme Conference. This conference attracts students, research scientists and faculty members from colleges and universities throughout the southeastern region. With the assistance of the GSU Foun ...
... The Chemistry Department at Georgia State University is the lead organizer and founder of the Southeast Enzyme Conference. This conference attracts students, research scientists and faculty members from colleges and universities throughout the southeastern region. With the assistance of the GSU Foun ...
Cloning and Characterization of Human Urocortin
... natural ligand for the type 2 CRF receptors. Using a genomiclibrary, we have cloned the humancounterpart of rat urocortin and localized it to humanchromosome2. Humanand rat urocortin share95% identity within the mature peptide region. Synthetic humanurocortin binds with high affinity to CRF receptor ...
... natural ligand for the type 2 CRF receptors. Using a genomiclibrary, we have cloned the humancounterpart of rat urocortin and localized it to humanchromosome2. Humanand rat urocortin share95% identity within the mature peptide region. Synthetic humanurocortin binds with high affinity to CRF receptor ...
Sequence-based predictions of membrane-protein topology, homology and insertion
... major role in the origin of the field of bioinformatics, which deals with annotation, storage and analysis of such biological data. Accordingly, one of the first disciplines within bioinformatics, and still one of the largest, has been that of sequence analysis. Methods for automatic annotation of ...
... major role in the origin of the field of bioinformatics, which deals with annotation, storage and analysis of such biological data. Accordingly, one of the first disciplines within bioinformatics, and still one of the largest, has been that of sequence analysis. Methods for automatic annotation of ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.