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Genetics Study Guide
Genetics Study Guide

... An organism that always produces offspring with the same form of a trait as the parent….all offspring have the same traits as the parent Instructions for an inherited trait…a segment of DNA on a chromosome that codes for a specific trait The different forms of a gene An allele whose trait always sho ...
CHAPTER 6 Molecular Genetics: From DNA to Proteins
CHAPTER 6 Molecular Genetics: From DNA to Proteins

... in which DNA is copied. It occurs during the synthesis (S) phase of the eukaryotic cell cycle. DNA replication begins when an enzyme breaks the bonds between complementary bases in DNA (see Figure 6.4). This exposes the bases inside the molecule so they can be “read” by another enzyme and used to bu ...
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File

... 4. Phenolic Compounds: are a large and diverse group of molecules, which includes many families of aromatic secondary metabolite in plants. 5. Enzymes: are group of molecules that serve as a catalyst with a high degree of specificity for a certain substrate or class of substrates. It can only act o ...
FREE Sample Here
FREE Sample Here

... Organic Substances contains the atoms carbon (and hydrogen). They are composed of small molecules covalently bonded together to form large polymers or macromolecules. The four major classes found in cells include carbohydrates, lipids, proteins, and nucleic acids ...
Document
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... The R groups can be saturated or unsaturated, the same or different ...
Construction of recombinant plasmid carrying the λ DNA fragment
Construction of recombinant plasmid carrying the λ DNA fragment

... the red gal + clones were not observed. RW842 does not revert spontaneously to gal + . In the case of transformation by RSF2124- AC plasmid the red gal + clones appeared but with low frequency. In contrast to the plating of int~xis+ phages the effect of complementation was not observed when int+xis~ ...
Water soluble Vit. Vit C: (Ascorbic Acid)
Water soluble Vit. Vit C: (Ascorbic Acid)

... Folic Acid Antagonist: Many drugs have been used for the treatment of malignant tumor and leukemia ,these drugs are more or less have a similar structure to the structure of folic acid , they inhibit DNA synthesis by a competitive inhibition to certain enzymes ,these are 6 mercaptopurine, methotrexa ...
Lecture 6
Lecture 6

... They are always negatively charged at neutral pH. All molecules will travel in the same direction Each additional nucleoside confers an additional charge, so charge is directly proportional to size. All molecules will have the same e The solution is to use a gel which consists of pores surrounded b ...
Facioscapulohumeral muscular dystrophy
Facioscapulohumeral muscular dystrophy

... With completion of the ‘human genome project’ has the gene causing FSHD been identified? Unfortunately the situation is a little more complex than as discussed (in answer 12.) above. Amongst genetic conditions, FSHD seems so far to be unique in that the genetic fault (‘mutation’) is the reduction ( ...
The Living World
The Living World

... The Hershey-Chase Experiment Viruses that infect bacteria have a simple structure DNA core surrounded by a protein coat Hershey and Chase used two different radioactive isotopes to label the protein and DNA Incubation of the labeled viruses with host bacteria revealed that only the DNA entered the ...
Applications of Recombinant DNA to Pathologic Diagnosis
Applications of Recombinant DNA to Pathologic Diagnosis

... material such that the chromosome breaks and a fragment of it is joined to a different chromosome. Cosmid: Plasmids into which the “cos” site of bacteriophage lambda has been inserted. A cosmid also allows plasmid molecules to be inserted into viral coat particles in vitro. DNA ligase: An enzyme cap ...
Agrobacterium tumefaciens
Agrobacterium tumefaciens

... circulate off shore, characterized by mild, rainy winters and long, hot, dry summers. Chemiosmosis The ability of certain membranes to use chemical energy to pump hydrogen ions and then harness the energy stored in the Hydrogen ion gradient to drive cellular work including ATP synthesis. Co factor A ...
Optional PowerPoint introduction to the case
Optional PowerPoint introduction to the case

... So far, you have discussed chirality amplification. This theory still requires a small excess of one enantiomer to begin the amplification process. Here you will discuss how that original excess appeared. One (disputed) theory of the original genesis of "chiral molecules" on Earth comes from outer s ...
GFP plasmid - Kiwi.mendelu.cz
GFP plasmid - Kiwi.mendelu.cz

... into a plasmid vector to create recombinant DNA molecules. ...
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bchm6280_lect1_16
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... 24.1 Nonspecific defenses against infection include the skin and mucous membranes, phagocytic cells, and antimicrobial proteins • The body’s first lines of defense against infection are nonspecific – They do not distinguish one infectious microbe from another ...
Genetic Manipulation of Bacteria
Genetic Manipulation of Bacteria

... what are called BACs - bacterial artificial chromosomes - which rely on the replication and partitioning system of low copy number plasmids such as F and the prophage of P1. Plasmid vectors have been manipulated to make it easier to detect or even select for the acquisition of an inserted fragment o ...
Polypeptides and Proteins
Polypeptides and Proteins

... Primary: sequence of amino acid residues. Secondary: way in which segments of polypeptide backbone are oriented in space; depends on planarity of peptide bond and, often, Hbonding. The only places in the protein chain where there is torsional flexibility is at the α-carbons: the angles Φ and Ψ can c ...
DNA Markers: Explanation of Validation and Utilization
DNA Markers: Explanation of Validation and Utilization

... ears and a hump, even though some of them are not genetically associated or linked with the ...
Accelerated Analysis of Amino Acids in Physiological
Accelerated Analysis of Amino Acids in Physiological

... difference was observed for ASA (12.9% RSD), which is due to the unstable nature of this compound: it converts easily to a pair of lactones. These compounds, referred to as Anhydrides I and II are also detectable chromatographically. ...
Abiogenesis
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... • RNA is (probably) still too complex to have arisen in one step • Plausible precursors are required • This is an area of ongoing research ...
Genomic DNA Purification Protocol
Genomic DNA Purification Protocol

... With the emergence of antimicrobial-resistant organisms and the increased prevalence of food-borne human pathogens, surveillance of these bacteria has become an important interest to public health. For example, methicillin-resistantStaphylococcus aureus (MRSA) is a leading cause of nosocomial infect ...
Protein Folding and The Impact of Mutations
Protein Folding and The Impact of Mutations

... Any change to the DNA is called a mutation The effect of a mutation is usually harmful, but it can also be beneficial or even have no impact whatsoever ...
A hypothesis on the possible contribution of free hypoxanthine and
A hypothesis on the possible contribution of free hypoxanthine and

... out at room temperature (RT) were compared to those at 60°C. Ala: alanine stan- ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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