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Genomic DNA Purification Protocol
Genomic DNA Purification Protocol

... With the emergence of antimicrobial-resistant organisms and the increased prevalence of food-borne human pathogens, surveillance of these bacteria has become an important interest to public health. For example, methicillin-resistantStaphylococcus aureus (MRSA) is a leading cause of nosocomial infect ...
Cells N5 Homework book - Deans Community High School
Cells N5 Homework book - Deans Community High School

... the base Thymine is relaced with a base called Uracil, represented by the letter U. This means that the codes for amino acids all contain the letter U instead of letter T. Use the genetic code to identify the amino acids being coded for in each of the sequences below. See if you can complete this ex ...
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... Figures 2A and 2B show a similar trend of average detection rate sharply decreasing from day 0 to day 9 followed by a slight additional decrease, except in female subjects’ urinary DNA preserved with EDTA. What is the source of this degradation, and how can the gender differences be explained? After ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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