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GCSE Cells Topic Learning Checklist
GCSE Cells Topic Learning Checklist

... Describe factors the affect the rate of diffusion Recall that a single-celled organism has a relatively large surface area to volume ratio to allow sufficient transport of molecules into and out of the cell Explain how the small intestine and lungs in mammals, gills in fish, and the roots and leaves ...
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... The discovery of cells was made possible by the development of the microscope in the 17th century. In 1665, the English scientist Robert Hooke used a microscope to examine a thin slice of cork. Hooke described it as consisting of “a great many little boxes.” These “little boxes” reminded him of the ...
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Artificial cell



An artificial cell or minimal cell is an engineered particle that mimics one or many functions of a biological cell. The term does not refer to a specific physical entity, but rather to the idea that certain functions or structures of biological cells can be replaced or supplemented with a synthetic entity. Often, artificial cells are biological or polymeric membranes which enclose biologically active materials. As such, nanoparticles, liposomes, polymersomes, microcapsules and a number of other particles have qualified as artificial cells. Micro-encapsulation allows for metabolism within the membrane, exchange of small molecules and prevention of passage of large substances across it. The main advantages of encapsulation include improved mimicry in the body, increased solubility of the cargo and decreased immune responses. Notably, artificial cells have been clinically successful in hemoperfusion.In the area of synthetic biology, a ""living"" artificial cell has been defined as a completely synthetically made cell that can capture energy, maintain ion gradients, contain macromolecules as well as store information and have the ability to mutate. Such a cell is not technically feasible yet, but a variation of an artificial cell has been created in which a completely synthetic genome was introduced to genomically emptied host cells. Although not completely artificial because the cytoplasmic components as well as the membrane from the host cell are kept, the engineered cell is under control of a synthetic genome and is able to replicate.
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