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Biology: semester one: course outline
Biology: semester one: course outline

... photosynthesis. In general terms, explain the role of redox reactions in photosynthesis. Describe the relationship between an action spectrum and an absorption spectrum. List the components of a photosystem and explain the function of each component. Trace the movement of electrons in linear electro ...
Cloning: A Critical Analysis of Myths and Media
Cloning: A Critical Analysis of Myths and Media

... animals rather than humans in their efforts to find effective treatments and cures. In addition, by using transgenic technology, extremely rare human or animal diseases can be produced in a sufficient number of animal subjects for study and experimentation, rather than relying only on naturally occu ...
Chapter 20 Prokaryotes
Chapter 20 Prokaryotes

... that photosynthesize. – Believed to be responsible for introducing oxygen into the primitive atmosphere.  Lack visible means of locomotion.  Can live in extreme environments. ...
University of Groningen Sugar transport in
University of Groningen Sugar transport in

... Due to the glycosylation, binding proteins can bind to concanavalin A (ConA) affinity columns [1,9,12,16,17], which allows the convenient and rapid enrichment of S-layer and binding proteins from a solubilized membrane fraction. Glycosylation is, however, not essential for substrate recognition, as ...
Dynamic changes of yak (Bos grunniens) gut microbiota during
Dynamic changes of yak (Bos grunniens) gut microbiota during

... alignment length, and finally we identified a total of 6754 KEGG orthologous groups (KOs). Classifications of ...
Supplementary Data
Supplementary Data

... Figure S6: The R1 domain: Top) Sequence alignment deduced from the HCA comparison of the N-terminal part of the CFTR R domain (here named the R1 domain) with the regulatory domains found in some bacterial ABC transporters immediately after their NBDs (TOBE domains). The sequences of six of these pr ...
Correlating mRNA and protein Abundance
Correlating mRNA and protein Abundance

... 441) have significantly uncorrelated mRNA and protein levels (2STDEV from trendline) Transcription Assoc. genes are 25% of the essential genes in yeast. Essential Genes as a group have higher correlations than the general yeast population 7% of Cell Cycle associated genes (n = 432) have ...
Lysines 72, 80 and 213 and aspartic acid 210 of the
Lysines 72, 80 and 213 and aspartic acid 210 of the

... No crystal structure of the L, lactis LacR repressor or any of the other members of the DeoR family is available yet. Therefore, it is impossible to predict the effects of individual mutations on the overall structure and, hence, biological activity of the LacR repressor. An extensive study has been ...
Probing the Performance Limits of the Escherichia
Probing the Performance Limits of the Escherichia

... April 2001, over 45 microbial genomes have been completely sequenced (TIGR microbial database; website http:// www.tigr.org) and bioinformatic tools have allowed the functional assignment of 45–80% of their coding regions (Pennisi, 1997). This newly acquired information can be used in conjunction wi ...
Molecular evolution of proteins and Phylogenetic Analysis Fred R
Molecular evolution of proteins and Phylogenetic Analysis Fred R

... Flanking region ...
Gene Section BUB1 (budding uninhibited by benzimidazoles 1 homolog (yeast))
Gene Section BUB1 (budding uninhibited by benzimidazoles 1 homolog (yeast))

... cancer cell line V400 revealed an internal deletion of 197 bp of this gene (Cahill et al., 1998). The deletion results in the remotion of codons 76 to 141 and creates a frameshift immediately thereafter. Sequence analysis of cDNA from another colorectal cancer cell line, V429, revealed a missense mu ...
Te gades
Te gades

... Why  Te#gades?   •  *Not  all  Te#gades  species  studied  has  this   double  lineage  of  Hodgkina   •  To  look  at  this  phenomena  phylogene0cally,   we  decided  to  sequence  the  cicadas  harboring   these  bacteria   •  Thus  we ...
Intrastrand Self-complementary Sequences in Bacillus subtilis DNA
Intrastrand Self-complementary Sequences in Bacillus subtilis DNA

... widely scattered throughout the B. subtilis genome were transformed by the DNA which contained secondary structure suggesting that the location of such sequences is not unique. The biological nature of the self-annealing DNA has been further characterized using transformation assays and by hybridiza ...
of the number of ISs / Genome
of the number of ISs / Genome

... Solution : Reannotation of ISs using comparative study by adopting the nomenclature defined by Chandler (1998) - ISs have one or two consecutive ORFs encoding transposase protein ...
The role of carbohydrate in sperm
The role of carbohydrate in sperm

... is carbohydrate mediated, then other carbohydrate epitopes are being recognized by ZP3 receptors located on the spermatozoa, e.g. either NAG (Miller et ai, 1992) and/or fucose (Bleil and Wassarman, 1988). The latter is based on the observation that treatment of mouse ZP3 with a-fucosidase reduced sp ...
Glycolytic enzymes localize to ribonucleoprotein
Glycolytic enzymes localize to ribonucleoprotein

... cause defects in germ cell development and transposon silencing mechanisms. Therefore, the entire glycolytic pathway, rather than individual components, might play a special role in germ cell specification and contribute to the protection of germline DNA against transposons. These data provide the f ...
Discovery of Paralogous Nuclear Gene Sequences Coding for the
Discovery of Paralogous Nuclear Gene Sequences Coding for the

... Thus, it is generally thought that suitable target regions for phylogenetic studies should be single-copy regions or, minimally, regions in which orthologous copies of multigene families can be unambiguously identified. In contrast to the chloroplast genome, there is a level in the plant taxonomic h ...
Histone Deacetylase 4 Antibody
Histone Deacetylase 4 Antibody

... members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about twofold larger than those of the class I members, and the deace ...
Type="Italic">AtGRP7 is involved in the
Type="Italic">AtGRP7 is involved in the

... transduction pathways [2, 4]. These components range from early signaling intermediates, such as G proteins and protein kinases/phosphatases, to transcription factors (TFs) and RNA metabolic proteins; thus, the modulation of ABA responses in plants involves a complex molecular network [2-9]. A famil ...
Phylogenetic tree construction based on amino acid composition
Phylogenetic tree construction based on amino acid composition

... classification was obtained through analysis of 16S rRNA sequences. Because organisms were randomly chosen in our previous study [10], it was difficult to evaluate the accuracy of the resulting classifications. In that study, vertebrates were completely classified into two groups— terrestrial and aq ...
DNA Sequencing of the eta Gene Coding for
DNA Sequencing of the eta Gene Coding for

... containing a markedly hydrophobic region in the middle. However, it is not yet known what domains in the nucleotide sequence of this gene play essential roles in coding for the biological properties of ETA. We have recently cloned the gene coding for ETB (etb) and determined the DNA sequence (unpubl ...
The novel genome organization of the insect picorna
The novel genome organization of the insect picorna

... virus families. The 3« ORF encodes the capsid proteins as confirmed by N-terminal sequence analysis of these proteins. The capsid protein coding region is unusual in two ways : firstly the cistron appears to lack an initiating methionine and secondly no subgenomic RNA is produced, suggesting that th ...
Sequence analysis of 16S rRNA, gyrB and catA genes and DNA
Sequence analysis of 16S rRNA, gyrB and catA genes and DNA

... of cells and nucleic acids prior to DNA purification. DDH was carried out as described by De Ley et al. (1970) under consideration of the modifications described by Huss et al. (1983) using a model Cary 100 Bio UV/VIS-spectrophotometer with a Peltier-thermostat-equipped 666 multicell changer and a t ...
Sequence analysis of 16S rRNA, gyrB and catA genes and DNA
Sequence analysis of 16S rRNA, gyrB and catA genes and DNA

... of cells and nucleic acids prior to DNA purification. DDH was carried out as described by De Ley et al. (1970) under consideration of the modifications described by Huss et al. (1983) using a model Cary 100 Bio UV/VIS-spectrophotometer with a Peltier-thermostat-equipped 666 multicell changer and a t ...
Off-target Effects: Disturbing the Silence of RNA
Off-target Effects: Disturbing the Silence of RNA

... Early studies in RNAi established that single base pair mismatches between the siRNA and the target transcript dramatically alter siRNA functionality.13 From this result it was inferred that overall sequence identity played a role in siRNA specificity, thus leading to the adoption of local alignment ...
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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