PRH/Hex - Biochemical Journal
... located downstream of the homeodomain in NK proteins. These differences suggest the possibility that PRH could equally be placed in a subclass of its own. The consensus PRH-binding site is 5 -C/TA/TATTAAA/G-3 as determined by SELEX (systematic evolution of ligands by exponential enrichment) experi ...
... located downstream of the homeodomain in NK proteins. These differences suggest the possibility that PRH could equally be placed in a subclass of its own. The consensus PRH-binding site is 5 -C/TA/TATTAAA/G-3 as determined by SELEX (systematic evolution of ligands by exponential enrichment) experi ...
D3.1 - transPLANT
... ENVO is a very general ontology maintained by known experts of bioontologies (S. Lewis, C. Mungall, M. Ashburner, B. Smith, …). ENVO contains terms for biomes, environmental features, and environmental material. The drawback of this general approach is that only a very small subset of the ontology m ...
... ENVO is a very general ontology maintained by known experts of bioontologies (S. Lewis, C. Mungall, M. Ashburner, B. Smith, …). ENVO contains terms for biomes, environmental features, and environmental material. The drawback of this general approach is that only a very small subset of the ontology m ...
General principles of cellular organization in the genome
... and extensive sharing of components implying protein multifunctionality. Incorporation of structural models for 484 proteins, single particle EM and cellular electron tomograms provided supporting structural details for this proteome organization. To understand basic principles of bacterial metaboli ...
... and extensive sharing of components implying protein multifunctionality. Incorporation of structural models for 484 proteins, single particle EM and cellular electron tomograms provided supporting structural details for this proteome organization. To understand basic principles of bacterial metaboli ...
Applied Biosystems Real-Time PCR Rapid Assay Development
... patents and foreign equivalents for research purposes only. No right for use in other applications, including the diagnosis of disease in humans, animals, or plants under any patents owned by Life Technologies, Inc. are covered by the purchase of this product. TaqMan Gene Expression and SNP Genotypi ...
... patents and foreign equivalents for research purposes only. No right for use in other applications, including the diagnosis of disease in humans, animals, or plants under any patents owned by Life Technologies, Inc. are covered by the purchase of this product. TaqMan Gene Expression and SNP Genotypi ...
The cuticle
... To whom correspondence should be addressed. E-mail: [email protected] or [email protected] ...
... To whom correspondence should be addressed. E-mail: [email protected] or [email protected] ...
Review: can diet influence the selective advantage of mitochondrial
... mitohormesis [7]. Although varied, this response appears to induce a wide-ranging cytoprotective state resulting in long lasting metabolic and biochemical changes. Remarkably, rather than being harmful, these changes may increase evolutionary potential and decrease susceptibility for disease. Althou ...
... mitohormesis [7]. Although varied, this response appears to induce a wide-ranging cytoprotective state resulting in long lasting metabolic and biochemical changes. Remarkably, rather than being harmful, these changes may increase evolutionary potential and decrease susceptibility for disease. Althou ...
Understanding the Regulation of Metabolic Enzyme Acetylation in E
... Global protein acetylation is a newly discovered phenomenon in bacteria. Of the more than 250 acetylations reported in E. coli, many are of metabolic enzymes [1-3]. Thus, acetylation could represent a novel posttranslational mechanism of metabolic control. Yet, almost nothing is known about the regu ...
... Global protein acetylation is a newly discovered phenomenon in bacteria. Of the more than 250 acetylations reported in E. coli, many are of metabolic enzymes [1-3]. Thus, acetylation could represent a novel posttranslational mechanism of metabolic control. Yet, almost nothing is known about the regu ...
Queuosine formation in eukaryotic tRNA occurs via a mitochondria
... Eubacteria are unique in their ability to synthesize Q. As part of this biosynthetic process, the eubacterial TGT enzyme inserts the Q-precursor molecule, 7-aminomethyl-7-deazaguanine (preQ1) into tRNA, which is then converted to Q by two further enzymatic steps at the tRNA level (6). Eukaryotes by ...
... Eubacteria are unique in their ability to synthesize Q. As part of this biosynthetic process, the eubacterial TGT enzyme inserts the Q-precursor molecule, 7-aminomethyl-7-deazaguanine (preQ1) into tRNA, which is then converted to Q by two further enzymatic steps at the tRNA level (6). Eukaryotes by ...
SOD is an enzyme with four different types of metal
... SOD is an enzyme with four different types of metal ions, dividing this family into Cu,Zn-, Fe-, Mn- and Ni-SODs. About 2 billion years ago during the oxygenation of biosphere the evolution of SOD and other antioxidant enzymes was probably triggered by production of O2 by photosynthetic organisms. ...
... SOD is an enzyme with four different types of metal ions, dividing this family into Cu,Zn-, Fe-, Mn- and Ni-SODs. About 2 billion years ago during the oxygenation of biosphere the evolution of SOD and other antioxidant enzymes was probably triggered by production of O2 by photosynthetic organisms. ...
Effect of Aminoguanidine (Inducible Nitric Oxide Synthase Inhibitor
... particularly high expression in heart, liver and kidney [16], while PDK3 is expressed in testes, kidney and brain [39]. PDK4 is highly expressed in several tissues, including heart [26,40], skeletal muscle [29,38], liver [41], kidney [16,37] and the pancreatic islets [37]. The distribution of the f ...
... particularly high expression in heart, liver and kidney [16], while PDK3 is expressed in testes, kidney and brain [39]. PDK4 is highly expressed in several tissues, including heart [26,40], skeletal muscle [29,38], liver [41], kidney [16,37] and the pancreatic islets [37]. The distribution of the f ...
Comparative Sequence Analysis of the Genomic Segment 6 of Four
... pelleting through a cushion of 30~ (w/v) sucrose. The virus pellet was resuspended in buffer containing 20 mMTris-HC1 pH 7.4 and 15 mM-EDTAand incubated at 37 °C for 1 h. Single capsid viral particles produced by this treatment were purified by isopycnic centrifugation in a CsCI gradient. Single-str ...
... pelleting through a cushion of 30~ (w/v) sucrose. The virus pellet was resuspended in buffer containing 20 mMTris-HC1 pH 7.4 and 15 mM-EDTAand incubated at 37 °C for 1 h. Single capsid viral particles produced by this treatment were purified by isopycnic centrifugation in a CsCI gradient. Single-str ...
Polymerase Chain Reaction In Ophthalmology
... • PCR cannot detect the organism for which primers have not been provided. So a narrow and well defined differential diagnosis is required for PCR to be effectively useful. PCR and Koch's postulates 6, 7 Koch's postulates include isolation of suspected pathogen from all cases of a disease, successfu ...
... • PCR cannot detect the organism for which primers have not been provided. So a narrow and well defined differential diagnosis is required for PCR to be effectively useful. PCR and Koch's postulates 6, 7 Koch's postulates include isolation of suspected pathogen from all cases of a disease, successfu ...
Fungal denitrification and nitric oxide reductase cytochrome P450nor
... occurrence of denitrification was previously thought to be restricted to bacteria (prokaryotes), and have characterized the fungal denitrification system. It comprises NirK (copper-containing nitrite reductase) and P450nor (a cytochrome P450 nitric oxide (NO) reductase (Nor)) to reduce nitrite to ni ...
... occurrence of denitrification was previously thought to be restricted to bacteria (prokaryotes), and have characterized the fungal denitrification system. It comprises NirK (copper-containing nitrite reductase) and P450nor (a cytochrome P450 nitric oxide (NO) reductase (Nor)) to reduce nitrite to ni ...
Cyclic-‐di-‐AMP: another second messenger enters the fray
... phosphate mutase gene (glmM), which encodes a protein involved in an initial step of peptidoglycan synthesis. In B. subtilis this three gene dacA, ybbR, glmM operon is constitutively expre ...
... phosphate mutase gene (glmM), which encodes a protein involved in an initial step of peptidoglycan synthesis. In B. subtilis this three gene dacA, ybbR, glmM operon is constitutively expre ...
Zebrafish Collagen Type I: Molecular and Biochemical
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
Recycling of vitamin B12 and NAD+ within the Pdu
... products (56). The extract was the first workable treatment for the disease. These events in turn led to discovery of the water soluble vitamin, called vitamin B12, in the liver juice in 1948 by Karl A. Folkers (181) and E. Lester Smith (212). In 1955, the B12 structure was elucidated by X-ray cryst ...
... products (56). The extract was the first workable treatment for the disease. These events in turn led to discovery of the water soluble vitamin, called vitamin B12, in the liver juice in 1948 by Karl A. Folkers (181) and E. Lester Smith (212). In 1955, the B12 structure was elucidated by X-ray cryst ...
Quantitative Analysis of the Kinetics of End
... The monomer-monomer interfaces are presumably the same at either end (and everywhere else) in the ®lament. As pointed out by Wegner (1982), the KD for monomer addition to either ®lament end cannot be different unless an independent source of chemical energy is provided to affect the binding to one e ...
... The monomer-monomer interfaces are presumably the same at either end (and everywhere else) in the ®lament. As pointed out by Wegner (1982), the KD for monomer addition to either ®lament end cannot be different unless an independent source of chemical energy is provided to affect the binding to one e ...
Characterization of the Sucrose Phosphate Phosphatase (SPP
... been characterized. The enzyme has been shown to be a dimer with a molecular mass of around 100 kDa, formed by subunits of approximately 50 kDa [19–21]. A carboxy-terminal domain of about 160 amino acids is present in higher plant SPPs that has been proposed to participate in dimerization (S6PPc dom ...
... been characterized. The enzyme has been shown to be a dimer with a molecular mass of around 100 kDa, formed by subunits of approximately 50 kDa [19–21]. A carboxy-terminal domain of about 160 amino acids is present in higher plant SPPs that has been proposed to participate in dimerization (S6PPc dom ...
The Protein Cevalently Linked to the 5'... of Poliovirus RNA by Victor Robert Ambros
... or 6 M guanidine HC1 indicates that it has a molecular weight of about ...
... or 6 M guanidine HC1 indicates that it has a molecular weight of about ...
Engineering Cytosolic Acetyl-CoA Metabolism in
... evolved strains were obtained, which can grow on glucose as the sole carbon source at maximum specific rates of 0.138 h-1, 0.148 h-1, 0.141 h-1, respectively. Several genetic changes were identified in the evolved Pdc negative strains by genome sequencing. Among these genetic changes, 4 genes were f ...
... evolved strains were obtained, which can grow on glucose as the sole carbon source at maximum specific rates of 0.138 h-1, 0.148 h-1, 0.141 h-1, respectively. Several genetic changes were identified in the evolved Pdc negative strains by genome sequencing. Among these genetic changes, 4 genes were f ...
EFFECTS OF INSULIN DEFICIENCY ON EXERCISE
... hours after exercise in healthy mice (p < 0.05) while p38 MAPK phosphorylation was decreased in diabetic mice three hours after exercise (p < 0.05). There were no significant changes in proteins PDK4, CPT1B, sirtuins 1, 3 and 6, ACC or Cyt c. These results suggest that diabetic mice have more pronou ...
... hours after exercise in healthy mice (p < 0.05) while p38 MAPK phosphorylation was decreased in diabetic mice three hours after exercise (p < 0.05). There were no significant changes in proteins PDK4, CPT1B, sirtuins 1, 3 and 6, ACC or Cyt c. These results suggest that diabetic mice have more pronou ...
Multiomics of tomato glandular trichomes reveals
... al., 2012; Schilmiller et al., 2012; Brückner et al., 2014), and no comprehensive study has been conducted to link the downstream biosynthesis steps to central and energy metabolisms in these cells. Understanding how the core metabolic network in these specialized cells is organized t ...
... al., 2012; Schilmiller et al., 2012; Brückner et al., 2014), and no comprehensive study has been conducted to link the downstream biosynthesis steps to central and energy metabolisms in these cells. Understanding how the core metabolic network in these specialized cells is organized t ...
Biosynthesis of Glucosyl Glycerol, a Compatible Solute, Using
... the intermolecular transglycosylation activity of ASase has gained increasing attention because it uses a relatively cheap substrate, sucrose, as well as its broad range of acceptor specificity [7, 8]. ASase can employ not only various glycones such as salicin [9] and arbutin [10] but also numerous ...
... the intermolecular transglycosylation activity of ASase has gained increasing attention because it uses a relatively cheap substrate, sucrose, as well as its broad range of acceptor specificity [7, 8]. ASase can employ not only various glycones such as salicin [9] and arbutin [10] but also numerous ...
Molecular and General Genetics.
... tryptophan produced IAA if tryptophan was present but did not synthesise IAA from indole. Similar results were obtained for a mutant strain with additional mutations in the genes ipdC and trpD . This suggests the existence of an alternative Trp-dependent route for IAA synthesis. On gluconate as a ca ...
... tryptophan produced IAA if tryptophan was present but did not synthesise IAA from indole. Similar results were obtained for a mutant strain with additional mutations in the genes ipdC and trpD . This suggests the existence of an alternative Trp-dependent route for IAA synthesis. On gluconate as a ca ...