BCH 401G Lecture 44 Eukaryotic gene expression Andres
... In general, eukaryotic RNA polymerases have little or no intrinsic affinity for their promoters. Initiation of transcription is almost always dependent on the action of one or, more often, several regulatory (activator) proteins. The extensive use of positive regulatory mechanisms is probably a cons ...
... In general, eukaryotic RNA polymerases have little or no intrinsic affinity for their promoters. Initiation of transcription is almost always dependent on the action of one or, more often, several regulatory (activator) proteins. The extensive use of positive regulatory mechanisms is probably a cons ...
Nucleic Acids - faculty at Chemeketa
... What will be the composition of the DNA strand complementary to –AGCCA– ? a. b. c. d. ...
... What will be the composition of the DNA strand complementary to –AGCCA– ? a. b. c. d. ...
10-DNA-TranslationControl
... The lac operon is also regulated by an activator The activator is a protein called CAP It binds to the CAP-binding site and gives the RNA polymerase more access to the promoter However, a “low glucose” signal molecule has to bind to CAP before CAP can bind to the DNA ...
... The lac operon is also regulated by an activator The activator is a protein called CAP It binds to the CAP-binding site and gives the RNA polymerase more access to the promoter However, a “low glucose” signal molecule has to bind to CAP before CAP can bind to the DNA ...
Unit 6B Learning Targets
... Transcription factors bind to specific DNA sequences and/or other regulatory proteins. b. Some of these transcription factors are activators (increase expression), while others are repressors (decrease expression). c. The combination of transcription factors binding to the regulatory regions at any ...
... Transcription factors bind to specific DNA sequences and/or other regulatory proteins. b. Some of these transcription factors are activators (increase expression), while others are repressors (decrease expression). c. The combination of transcription factors binding to the regulatory regions at any ...
UTACCEL 2010
... •Easy to perform crosses •Large numbers or progeny •Interesting features e.g. Frog morphogenesis •Plant photosynthesis •Representative of diverse lineages •Similar to ourselves (mammals) •Extensive knowledge base ...
... •Easy to perform crosses •Large numbers or progeny •Interesting features e.g. Frog morphogenesis •Plant photosynthesis •Representative of diverse lineages •Similar to ourselves (mammals) •Extensive knowledge base ...
Gene Expression
... A large signaling network Characterize “devices” Identify “connections” Little spatial segregation Physical systems use channels to direct signals; media are common to many channels • Biological systems use highly differentiated chemical complementation. ...
... A large signaling network Characterize “devices” Identify “connections” Little spatial segregation Physical systems use channels to direct signals; media are common to many channels • Biological systems use highly differentiated chemical complementation. ...
Regulation
... 2. Definition of constitutive, inducible, and repressible enzyme systems. Lectures will focus on regulatory mechanisms in which the central theme is that control is mediated by low molecular substances that are either synthesized by the cell or present in the environment. These low MW molecules, cal ...
... 2. Definition of constitutive, inducible, and repressible enzyme systems. Lectures will focus on regulatory mechanisms in which the central theme is that control is mediated by low molecular substances that are either synthesized by the cell or present in the environment. These low MW molecules, cal ...
From DNA to Protein: Transcription and Translation
... replication in that the DNA is unwound and complementary nucleotides are added. Differences: • Only a gene is copied, not the whole chromosome. • RNA nucleotides are added instead of DNA nucleotides. – Uracil is paired with adenine instead of thymine. • Transcription occurs on an ongoing basis as pr ...
... replication in that the DNA is unwound and complementary nucleotides are added. Differences: • Only a gene is copied, not the whole chromosome. • RNA nucleotides are added instead of DNA nucleotides. – Uracil is paired with adenine instead of thymine. • Transcription occurs on an ongoing basis as pr ...
Lecture 15 POWERPOINT here
... We could perform alternative splicing as we saw in the last lecture. We could control how much of the mRNA was transported to the cytoplasm. We could control how much protein was made by the ribosomes. We could even regulate which proteins were activated once they have been made. ...
... We could perform alternative splicing as we saw in the last lecture. We could control how much of the mRNA was transported to the cytoplasm. We could control how much protein was made by the ribosomes. We could even regulate which proteins were activated once they have been made. ...
Chapter 1 Study Questions
... Colinearity of gene and protein 6. Eukaryotic transcription Promoters Enhancers/Silencers Transcription factors 7. RNA processing GT-AG rule Branch site Splicesome Capping Polyadenylation 8. Translation Ribosomes Genetic code Wobble hypothesis 9. Post-translational modificati ...
... Colinearity of gene and protein 6. Eukaryotic transcription Promoters Enhancers/Silencers Transcription factors 7. RNA processing GT-AG rule Branch site Splicesome Capping Polyadenylation 8. Translation Ribosomes Genetic code Wobble hypothesis 9. Post-translational modificati ...
6D * Recognize that a gene expression is a regulated process.
... Lactose present (enzymes are needed) Lactose binds to repressor and changes its shape= Can’t bind to the Operator RNA Polymerase transcribes genes into mRNA translation Enzymes are made to break down lactose sugar for energy ...
... Lactose present (enzymes are needed) Lactose binds to repressor and changes its shape= Can’t bind to the Operator RNA Polymerase transcribes genes into mRNA translation Enzymes are made to break down lactose sugar for energy ...
PPT File
... with single-stranded RNA. It infects white blood cells. HIV is enclosed in a membrane from the previous host cell—it fuses with the new host cell’s membrane. After infection, RNA-directed DNA synthesis is catalyzed by reverse transcriptase. Two strands of DNA are synthesized and reside in the host’s ...
... with single-stranded RNA. It infects white blood cells. HIV is enclosed in a membrane from the previous host cell—it fuses with the new host cell’s membrane. After infection, RNA-directed DNA synthesis is catalyzed by reverse transcriptase. Two strands of DNA are synthesized and reside in the host’s ...
Molecular Genetics (Unit 6 and Unit 6.2) Study Guide Each of the
... Each of the major scientists, their experiment, their contribution to molecular biology Structure of DNA and RNA o Direction, components, differences and similarities between the two, reads/builds, 5’ and 3’ ends, antiparallel, H-bonding, nucleotide/nucleoside, o Types of RNA – job of each, structur ...
... Each of the major scientists, their experiment, their contribution to molecular biology Structure of DNA and RNA o Direction, components, differences and similarities between the two, reads/builds, 5’ and 3’ ends, antiparallel, H-bonding, nucleotide/nucleoside, o Types of RNA – job of each, structur ...
Chapter 18, 19, 20 Summaries
... important in development of embryos • Almost all the genes in a cell are genetically identical, so how do we get our many types of cells? • Differential gene expression is the expression of different genes by cells with the same genome • Errors in gene expression can lead to cancer and other disease ...
... important in development of embryos • Almost all the genes in a cell are genetically identical, so how do we get our many types of cells? • Differential gene expression is the expression of different genes by cells with the same genome • Errors in gene expression can lead to cancer and other disease ...
Regulation of Gene Expression
... Control of Transcription DNA has “on” and “off” switches Activator –protein that binds near gene’s promoter region - allows RNA polymerase to transcribe (allows it to fit) Repressor – protein that binds to DNA and prevents RNA polymerase from binding -coded for by “regulator” gene ...
... Control of Transcription DNA has “on” and “off” switches Activator –protein that binds near gene’s promoter region - allows RNA polymerase to transcribe (allows it to fit) Repressor – protein that binds to DNA and prevents RNA polymerase from binding -coded for by “regulator” gene ...
Gene Expression
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
Gene Expression
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
... All levels of transcription and translation are involved: 1. DNA sequence will encode for specific regulation – promoters, exons/introns, etc 2. RNAs – will affect which genes complete the process to become proteins 3. Proteins – function as enzymes and machinery to activate or silence specific gene ...
Chapter 17 Transcriptional Regulation In Eukaryotes
... -initiation of transcription is the most pervasively (왕성하게) regulated step, i.e., before the assembly of RNA Pol II machinery -Diverse (다양한) regulatory factors are involved 1)activators & repressors: DNA binding proteins and help or hinder (방해하다) transcription initiation at specific genes in respons ...
... -initiation of transcription is the most pervasively (왕성하게) regulated step, i.e., before the assembly of RNA Pol II machinery -Diverse (다양한) regulatory factors are involved 1)activators & repressors: DNA binding proteins and help or hinder (방해하다) transcription initiation at specific genes in respons ...
File - Mrs. Badger`s Honors Biology Class
... _____ 2. The main function of tRNA is to a. carry a message that, when translated, forms proteins. b. form a portion of ribosomes, a cell’s protein factories. c. string together complementary RNA and DNA strands. d. bring amino acids from the cytoplasm to the ribosomes. _____ 3. What is the term for ...
... _____ 2. The main function of tRNA is to a. carry a message that, when translated, forms proteins. b. form a portion of ribosomes, a cell’s protein factories. c. string together complementary RNA and DNA strands. d. bring amino acids from the cytoplasm to the ribosomes. _____ 3. What is the term for ...
Protein Synthesis - Helena High School
... Use notes from the PowerPoint and complete the following questions. This will be the study guide for questions about transcription/translation. 1. DNA codes for what macromolecule? Provide three examples of proteins necessary in our bodies a. b. c. 2. Where is the code within the DNA molecule that p ...
... Use notes from the PowerPoint and complete the following questions. This will be the study guide for questions about transcription/translation. 1. DNA codes for what macromolecule? Provide three examples of proteins necessary in our bodies a. b. c. 2. Where is the code within the DNA molecule that p ...
Lecture 4: DNA transcription
... Performed by spliceosomes (large RNA-protein complex made of small nuclear ribonucleoproteins) Recognise exon-intron boundaries and splice exons together by transesterification reactions Cell type-specific splicing ...
... Performed by spliceosomes (large RNA-protein complex made of small nuclear ribonucleoproteins) Recognise exon-intron boundaries and splice exons together by transesterification reactions Cell type-specific splicing ...
Controlling Gene Expression
... There are four levels of control: ◦ transcriptional (controls transcription from DNA to mRNA) ◦ posttranscriptional (controls the removal of introns) ◦ translational (controls rate that mRNA is activated through ribosomes) ◦ posttranslational (affects the rate proteins can leave the cell) ...
... There are four levels of control: ◦ transcriptional (controls transcription from DNA to mRNA) ◦ posttranscriptional (controls the removal of introns) ◦ translational (controls rate that mRNA is activated through ribosomes) ◦ posttranslational (affects the rate proteins can leave the cell) ...
Transcriptional Control
... A. Structural Genes: The sequence of genes required to produce the desired product. Many are part of the same metabolic pathway and are in a specific order. ...
... A. Structural Genes: The sequence of genes required to produce the desired product. Many are part of the same metabolic pathway and are in a specific order. ...