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PG1005 Lecture 17 Gene Transcription
PG1005 Lecture 17 Gene Transcription

... transcribed into a portable template set of instructions for protein synthesis •  Detail the sequence of events occurring during the initiation, elongation and termination of transcription •  Describe the reactions catalysed by the spliceiosome and define what introns and exons •  Provide examples o ...
Virtual Labs: Class Set Building DNA, transcription, translation
Virtual Labs: Class Set Building DNA, transcription, translation

... 4. What is the name of the protein found in hair and nails? 5. List the different types of proteins and give an example of each and the function. 6. Write the name and function of each molecule involved in protein synthesis. 7. How are our traits determined? 8. How are our traits inherited? 2. Next: ...
Proteins
Proteins

... pries DNA apart and hooks RNA nucleotides together from the DNA code Promoter region on DNA: where RNA polymerase attaches and where initiation of RNA begins ...
Mock Exam 2BY330 Summer 2014 Assume that 4 molecules of
Mock Exam 2BY330 Summer 2014 Assume that 4 molecules of

... 9. Describe the “9 + 2 arrangement” of microtubules. In what two structures can this arrangement be found? ...
Eukaryotic Genomes - Building Directory
Eukaryotic Genomes - Building Directory

... All cells in an organism contain an identical genome (set of genes) However, the genes expressed in the cells of each type are unique Most of the DNA in eukaryotic genomes are noncoding – unsure of its purpose  25,000 genes in humans  Only about 1.5% codes for protein The expression of specific ge ...
DNA Technology
DNA Technology

... So what does all this mean? • We can already economically sequence a human genome. • These technologies present a huge variety of opportunities and dangers. • Your generation must be aware of these technologies as you will make the ultimate decisions about how these technologies are used. ...
Targeted knock-up of endogenous genes using a
Targeted knock-up of endogenous genes using a

The aim of the thesis was to characterize chosen expression vectors
The aim of the thesis was to characterize chosen expression vectors

... The aim of the thesis was to characterize chosen expression vectors used in biotechnologically important bacterial species, Corynebacterium glutamicum, and to test their use in studies of promoter activity control by sigma factors of RNA polymerase. Different properties of these vectors (level of ex ...
Gene Regulation of Eukaryotes
Gene Regulation of Eukaryotes

... A regulatory DNA sequence that greatly ...
Proteins
Proteins

... Alternative splicing • There are more than 1,000,000 different human antibodies. How is this possible with only ~30,000 genes? • Alternative splicing refers to the different ways of combining a gene’s exons. This can produce different forms of a protein for the same gene. • Alternative pre-mRNA spl ...
Document
Document

Tuesday5/10
Tuesday5/10

... The ability to repair damaged DNA is critical to long-term survival. Individuals with xeroderma pigmentosum produce defective repair enzymes. Without these repair enzymes, mutated DNA in skin cells (UV) is not repaired, leading to skin cancers. ...
Review Topics for Final Part 2
Review Topics for Final Part 2

A comprehensive catalogue of human RNA-binding
A comprehensive catalogue of human RNA-binding

... the team were able to map so-called connectivity quantitative trait loci (cQTLs). These cQTLs are natural genetic variants that influence the regulatory interactions of specific transcription factors and their target genes (for example, a polymorphism that occurs in the coding or promoter sequence o ...
biological sciences 354
biological sciences 354

... Prerequisites: Students must have Graduate Standing or passed BioSci 325 (P) or BioSci 315 (P) with C or better Course Content: The goal of this course is to provide students with a comprehensive understanding of transcriptional and post-transcriptional regulation of eukaryotic genes. This goal will ...
chapt13_image
chapt13_image

... • If inherited, the gene is not expressed • Transcriptional control is the most critical of all controls • No operons like those in prokaryotic cells have been found in eukaryotes • Every cell contains transcriptional factors, proteins that help regulate transcription ...
Powerpoint file - revised
Powerpoint file - revised

... Half-life of most mRNAs is short (on the order of a few minutes). ...
Biology 340 Molecular Biology
Biology 340 Molecular Biology

... Other regulatory elements are found in genes expressed only in certain tissues or that are coordinately controlled in response to a particular cellular signal. Globin genes: CCAAT box Muscle specific genes: E box, CANNTG --Elements such as the TATA box and Sp1 sites are found in close proximity to t ...
Cell type specific chromatin architecture defines erythropoiesis and
Cell type specific chromatin architecture defines erythropoiesis and

... tity  of  EB  and  MK.  We  established  regulatory  elements  opening  dynamics  from  the  haematopoietic  stem  cell   compartment  (HSC)  through  a  series  of  progressively  lineage-­‐restricted  progenitors  to  EB  and  MK  using   ...
Characterization of Genes Expressed During the Early Stages of
Characterization of Genes Expressed During the Early Stages of

... clones were identified. After DNA sequence characterization, the majority of these clones were identified by sequence homology and categorized by function. The largest group of genes encodes a range of proteins involved in ribosome biosynthesis, translation and post-translational modification. This ...
Lecture 6, Exam III Worksheet Answers
Lecture 6, Exam III Worksheet Answers

... within the protein? Which causes only minimal damage usually? 1. Silent mutation- causes no change within the protein. A change in a base pair may make one codon into another codon that codes for the exact same amino acid as the first one. 2. Missense mutation- usually causes only minimal damage. Th ...
Gene Regulation
Gene Regulation

... do not alter DNA sequence, they may be passed to future generations of cells • The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence is called ...
Lecture 40_GeneRegulationI_transcriptional_control_RoadMap
Lecture 40_GeneRegulationI_transcriptional_control_RoadMap

... o Four subunits form the core: α, α, β, β’ o The “holoenzyme” (functional RNA Pol) is made of the core plus σ factor o σ factor recognizes and binds the promoter region • Pribnow Box: TATAAT consensus sequence o Part of the promoter sequence in bacterial promoters o About 10 bp upstream of transcrip ...
Ch. 19 The Organization and Control of Eukaryotic Genomes
Ch. 19 The Organization and Control of Eukaryotic Genomes

... Requires protein-protein interactions to initiate transcription Key to efficient transcription are control elements ...
Transcription
Transcription

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Silencer (genetics)

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